Abstract:
:Drug-resistant epilepsy is an important clinical challenge, both diagnostically and therapeutically. More and more surgical options are being considered, but precise presurgical assessment is necessary. We prospectively studied eight patients with drug-resistant epilepsy, who underwent clinical examination, single photon emission computed tomography (SPECT) and interictal MRI, including diffusion- and perfusion-weighted echoplanar sequences. Lesions suspected on SPECT of being epileptogenic showed mild hypoperfusion, while the diffusion-weighted MRI (DWI) revealed increased apparent diffusion coefficients relative to the other side. However, these abnormalities were not visible on the corresponding maps. We showed that DWI and perfusion-weighted MRI could be used confirm the characteristics and site of an epileptogenic area in patients with drug-resistant epilepsy.
journal_name
Neuroradiologyjournal_title
Neuroradiologyauthors
Heiniger P,el-Koussy M,Schindler K,Lövblad KO,Kiefer C,Oswald H,Wissmeyer M,Mariani L,Donati F,Schroth G,Weder Bdoi
10.1007/s00234-002-0785-zsubject
Has Abstractpub_date
2002-06-01 00:00:00pages
475-80issue
6eissn
0028-3940issn
1432-1920journal_volume
44pub_type
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