MR spectroscopy in the evaluation of recurrent contrast-enhancing lesions in the posterior fossa after tumor treatment.

Abstract:

:Recurrent contrast-enhancing lesions arising within foci of prior brain neoplasms treated with chemotherapy and/or radiation therapy pose a significant diagnostic dilemma, as they may represent recurrent or residual tumor, treatment-related changes, or a combination of both. Those lesions specifically in the posterior fossa are even more difficult to assess, given the technical limitations of 2D CSI in the infratentorial compartment. We explored the feasibility of 2D-CSI MR spectroscopy in the evaluation of recurrent contrast-enhancing lesions in eight consecutive patients who had undergone treatment for posterior fossa or brainstem tumors. Mean Cho/Cr (choline/creatine) ratios obtained by 2D-CSI in recurrent tumor, treatment-related changes, and normal white matter were 2.93, 1.62, and 0.97, respectively, mean Cho/NAA (choline/N-Acetyl aspartate) ratios were 4.34, 1.74, and 0.93, and mean NAA/Cr (N-acetyl aspartate/creatine) ratios were 0.74, 0.92, and 1.26, respectively. In conclusion, also in the posterior fossa, MR spectroscopy is likely to be useful as an adjunct to conventional imaging characteristics in distinguishing recurrent tumor from treatment-related changes, irrespectively of the MRS technique used. In most cases spectra of diagnostic quality can be obtained using 2D-CSI to include coverage of both the lesion and its vicinity.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

Weybright P,Maly P,Gomez-Hassan D,Blaesing C,Sundgren PC

doi

10.1007/s00234-004-1195-1

subject

Has Abstract

pub_date

2004-07-01 00:00:00

pages

541-9

issue

7

eissn

0028-3940

issn

1432-1920

journal_volume

46

pub_type

杂志文章
  • Resistive NMR of intracranial hematomas.

    abstract::Comparison between computed tomography and nuclear magnetic resonance imaging in 17 patients with intracranial hematomas indicates a distinct role for NMR in evaluating the stable patient with hematoma. NMR is useful for delineating the extent of the hematoma, the relationship of the hematoma to brain anatomy, and the...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00342511

    authors: Zimmerman RA,Bilaniuk LT,Grossman RI,Levine RS,Lynch R,Goldberg HI,Samuel L,Edelstein W,Bottomley P,Redington RW

    更新日期:1985-01-01 00:00:00

  • Contrast-enhanced MRI of intrasellar arachnoid cysts: relationship between the pituitary gland and cyst.

    abstract::We recently encountered two large intrasellar arachnoid cysts extending to the suprasellar region. The intensity of the cyst contents was identical to that of the cerebrospinal fluid on both T1- and T2- weighted MRI. On contrast-enhanced MRI, the pituitary gland was compressed posteroinferiorly and flattened in the se...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00626100

    authors: Nomura M,Tachibana O,Hasegawa M,Kohda Y,Nakada M,Yamashima T,Yamashita J,Suzuki M

    更新日期:1996-08-01 00:00:00

  • Neuroendovascular magnetic navigation: clinical experience in ten patients.

    abstract:INTRODUCTION:The magnetic navigation system consists of an externally generated magnetic field that is used to control and steer a magnetically tipped microguidewire. The goal of this study was to demonstrate that the use of the magnetic navigation system and its magnetic microguidewire is feasible and safe in all type...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-006-0202-0

    authors: Dabus G,Gerstle RJ,Cross DT 3rd,Derdeyn CP,Moran CJ

    更新日期:2007-04-01 00:00:00

  • Pericallosal lipoma extending through the choroidal fissure: US/CT/MRI correlation.

    abstract::Choroid plexus lipomas (CPL) are known to be associated with pericallosal lipomas (lipomas of the corpus callosum--LCC). Twenty-six cases have previously been reported. Approximately half of these lipomas are connected via the choroidal fissure (LCC-CPL); this connection is almost always bilateral. We present an unusu...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00596500

    authors: Melin GI,Keller MS

    更新日期:1992-01-01 00:00:00

  • CT scan appearances in Leigh's disease (subacute necrotizing encephalomyelopathy).

    abstract::Four cases of Leigh's disease (subacute necrotizing encephalomyelopathy), two confirmed at postmortem examination, have been investigated recently by CT scanning. All four showed the same symmetrical areas of low attenuation in the basal ganglia, especially the putamina. These areas corresponded with the typical areas...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00395200

    authors: Hall K,Gardner-Medwin D

    更新日期:1978-01-01 00:00:00

  • In vivo quantitative whole-brain diffusion tensor imaging analysis of APP/PS1 transgenic mice using voxel-based and atlas-based methods.

    abstract:INTRODUCTION:Diffusion tensor imaging (DTI) has been applied to characterize the pathological features of Alzheimer's disease (AD) in a mouse model, although little is known about whether these features are structure specific. Voxel-based analysis (VBA) and atlas-based analysis (ABA) are good complementary tools for wh...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-013-1195-0

    authors: Qin YY,Li MW,Zhang S,Zhang Y,Zhao LY,Lei H,Oishi K,Zhu WZ

    更新日期:2013-08-01 00:00:00

  • Spinal cord magnetic resonance imaging in autosomal dominant hereditary spastic paraplegia.

    abstract::Hereditary spastic paraplegia (HSP) is a genetically heterogeneous group of neurodegenerative disorders characterized by progressive lower extremity weakness and spasticity. HSP pathology involves axonal degeneration that is most pronounced in the terminal segments of the longest descending (pyramidal) and ascending (...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-005-1415-3

    authors: Hedera P,Eldevik OP,Maly P,Rainier S,Fink JK

    更新日期:2005-10-01 00:00:00

  • Intracranial fibromuscular dysplasia and stroke in children.

    abstract::Fibromuscular dysplasia (FMD) is an arterial lesion of unknown origin which may sometimes affect intracranial arteries. In recent years a few rare cases, mostly involving younger people, have been described. The present case concerns a child of 8 years in whom the finding of hemiplegia led to a diagnosis of intracrani...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00344830

    authors: Lemahieu SF,Marchau MM

    更新日期:1979-08-15 00:00:00

  • MRI of intracerebral haematoma at low field (0.15T) using T2 dependent partial saturation sequences.

    abstract::Results of MRI at 0.15T in twelve successive patients with intracerebral haematoma are reviewed. Using T2 weighted spin echo (SE) and partial saturation (PS without a refocussing 180 degree pulse) sequences, low intensity areas were seen in eleven of the twelve cases. These included central regions (three cases), a pe...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00404099

    authors: Bydder GM,Pennock JM,Porteous R,Dubowitz LM,Gadian DG,Young IR

    更新日期:1988-01-01 00:00:00

  • Amyloid tumor of the orbit.

    abstract::A patient with an amyloid tumor of the orbit was studied by computed tomographic scanning. The tumor density was 10 delta units unenhanced and 72 units enhanced. ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00346872

    authors: Cohen MM,Lessell S

    更新日期:1979-09-26 00:00:00

  • Cervical analgesic facet joint arthrography.

    abstract::We report on our experience with cervical analgesic facet joint arthrography in 11 patients (30 joints), of whom nine had previous spinal surgery. In this type of patient we have found the procedure to be a diagnostic test as well as a preoperative guide to the neurosurgeon, but not a permanent therapy. ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF02426454

    authors: Hove B,Gyldensted C

    更新日期:1990-01-01 00:00:00

  • Membrane stain in chronic subdural hematoma: a rare angiographic sign. A case report.

    abstract::Chronic subdural hematoma is diagnosed angiographically by the presence of an avascular zone as a result of medial displacement of the cerebral surface vessels from the inner table. A rare angiographic sign, membrane stain, is reported in a case of chronic subdural hematoma. The stain is presumed to represent the vasc...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00369091

    authors: Kumar AJ,Koslow M,George AE

    更新日期:1980-01-01 00:00:00

  • Magnification angiography of dural carotid-cavernous sinus fistulae with emphasis on clinical and angiographic evolution.

    abstract::Eleven patients with dural carotid-cavernous sinus fistulae were studied with selective magnification angiography. The angiographic features of this condition were analyzed in detail. The arterial plexus normally present in and around the cavernous sinus has been thought to rupture into the sinus and establish an arte...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00347804

    authors: Takahashi M,Nakano Y

    更新日期:1980-01-01 00:00:00

  • Syndesmo-odontoid joint and calcium pyrophosphate dihydrate deposition disease (CPPD).

    abstract::Twenty-seven patients with definite or probable CPPS have been investigated with systematic frontal and lateral tomograms of the cervicooccipital region. In 12 cases there were calcifications of the syndesmo-odontoid region. These calcifications are of two different types: linear calcifications (5 cases) and mottled c...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00439211

    authors: Dirheimer Y,Bensimon C,Christmann D,Wackenheim C

    更新日期:1983-01-01 00:00:00

  • Cerebral sparganosis: analysis of 34 cases with emphasis on CT features.

    abstract::Cerebral sparganosis is a rare parasitic CNS disease, producing chronic active granulomatous inflammation. We retrospectively reviewed the clinical data, CT scans and histopathologic specimens in 34 patients with cerebral sparganosis. The majority of the patients (89%) were rural inhabitants; 75% had a history of inge...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00588423

    authors: Chang KH,Chi JG,Cho SY,Han MH,Han DH,Han MC

    更新日期:1992-01-01 00:00:00

  • A case of ochronosis: MRI of the lumbar spine.

    abstract::We present the MRI features of the lumbar spine in a patient with ochronosis. ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340000428

    authors: Choudhury R,Rajamani SS,Rajshekhar V

    更新日期:2000-12-01 00:00:00

  • Primary intrasellar germinoma with synchronous pineal tumor.

    abstract::Germinomas arising within the sella turcica are extremely rare. The association of intrasellar and a pineal region tumours is even more unusual. We report a 30-year-old man with germinomas in the sellar and pineal region. ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340050521

    authors: Ballesteros MD,Durán A,Arrazola J,Redondo MJ,Bordiú E,de Abajo S,Charro AL

    更新日期:1997-12-01 00:00:00

  • The evaluation of occipital lobe atrophy by computerized tomography before consideration of vertebral artery reconstructive surgery.

    abstract::Occipital lobe atrophy can be identified on CT. In a review of 90 selected cases with brain ischemia symptoms, 45 cases were found to have hindbrain ischemia with symptoms of vertigo and/or 'blurred vision.' Ten cases (22%) had normal CT studies and 35 cases (78%) had abnormal CT studies. The CT brain scan of the cere...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00395225

    authors: Dobben G,Valvassori G,Mafee M

    更新日期:1978-01-01 00:00:00

  • Cranial computed tomography of patients with malignant melanoma.

    abstract::Sixty-eight patients with malignant melanoma were examined by CCT and the findings analyzed. Cerebral metastases were detected in 19 patients. Meningiomas were found in three patients, one with neurological symptoms and two without. Typical metastases less than 10 mm in diameter were located superficially in the grey ...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00346752

    authors: Holtås S,Cronqvist S

    更新日期:1981-01-01 00:00:00

  • Carotid artery occlusion and computed tomography. A clinicoradiological study.

    abstract::Computed tomography (CT scanning) was carried out on 35 patients with proven occlusion of the carotid artery. There was a clear correlation of the clinical picture with the CT demonstration of cerebral infarct; 14 patients had no identifiable infarct. The findings were also correlated with angiographic data. The degre...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00345262

    authors: Radü EW,Moseley IF

    更新日期:1978-11-24 00:00:00

  • Atypical demyelinating lesions in patients with multiple sclerosis.

    abstract::We describe an atypical MRI appearance of multiple sclerosis (MS). Lesions characterized on T2-weighted images by a well-defined rim of increased signal intensity and a concentric region of higher signal intensity were seen in 6 of 132 patients with MS. On T1-weighted images these lesions were evident as regions of lo...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00588333

    authors: Yetkin Z,Haughton VM

    更新日期:1995-05-01 00:00:00

  • The value of computed tomography in cerebral syphilis.

    abstract::The computed tomographic findings of three patients with cerebral syphilis, including cerebral gumma, which regressed completely under penicillin therapy, syphilitic angiitis with cerbral infarction, and syphilitic cerebral atrophy, are reported. CT is unable to provide specific diagnostic data for these conditions. T...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00345725

    authors: Godt P,Stoeppler L,Wischer U,Schroeder HH

    更新日期:1979-10-31 00:00:00

  • Local intra-arterial fibrinolysis in thromboembolic "T" occlusions of the internal carotid artery.

    abstract::Local intra-arterial fibrinolysis (LIF) is considered to support spontaneous recanalisation, which does not usually occur fast enough to prevent an infarct. Therefore, LIF may, at least theoretically, be especially useful in occlusions with large thromboembolic masses. We report our experience of LIF with urokinase in...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340050375

    authors: Urbach H,Ries F,Ostertun B,Solymosi L

    更新日期:1997-02-01 00:00:00

  • PHACES syndrome: a review of eight previously unreported cases with late arterial occlusions.

    abstract::PHACE and PHACES are acronyms for a syndrome of variable expression comprising posterior cranial fossa malformations, facial haemangiomas, arterial anomalies, aortic coarctation and other cardiac disorders, ocular abnormalities and stenotic arterial disease. We review five girls and three boys aged 1 month-14 years wi...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-002-0902-z

    authors: Bhattacharya JJ,Luo CB,Alvarez H,Rodesch G,Pongpech S,Lasjaunias PL

    更新日期:2004-03-01 00:00:00

  • MRI of primary meningeal sarcomas in two children: differential diagnostic considerations.

    abstract::Meningeal sarcomas are very rare, highly aggressive tumours affecting children more frequently than adults. The clinical course and MRI of meningeal sarcomas in two cases are discussed with special regard to possible misinterpretation. In one case MRI demonstrated a circumscribed mass in contact with the meninges, wit...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340050399

    authors: Pfluger T,Weil S,Weis S,Bise K,Egger J,Hadorn HB,Hahn K

    更新日期:1997-03-01 00:00:00

  • MRI of active otosclerosis.

    abstract::Our aim was to determine whether MRI reliably shows pathology in patients with active otosclerosis (otospongiosis). We studied five patients with clinical and audiometric signs of this disorder and positive findings on high-resolution CT and tympanocochlear scintigraphy. Contrast enhancement of otospongiotic lesions w...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340050445

    authors: Ziyeh S,Berlis A,Ross UH,Reinhardt MJ,Schumacher M

    更新日期:1997-06-01 00:00:00

  • Tumors and cysts.

    abstract::"Congenital" tumors that cause hydrocephalus early in life are large masses and can easily be detected by ultrasound. CT is better for differentiating among the diverse types of mass lesions and is performed after screening by ultrasound. In our experience, ultrasound has proved successful for visualizing all of the i...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/BF00344100

    authors: Chuang S,Harwood-Nash D

    更新日期:1986-01-01 00:00:00

  • Primary CNS lymphoma in the spinal cord: clinical manifestations may precede MRI detectability.

    abstract::We report a 36-year-old woman whose first MRI after developing symptoms of cervical nerve root irritation was normal. Eight months later, after progression to tetraparesis and demonstration of an extensive contrast-enhancing intramedullary lesion giving high signal on T2-weighted images, the diagnosis of lymphoblastic...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002340100701

    authors: Herrlinger U,Weller M,Küker W

    更新日期:2002-03-01 00:00:00

  • Chronological changes in nonhaemorrhagic brain infarcts with short T1 in the cerebellum and basal ganglia.

    abstract::Our purpose was to investigate nonhaemorrhagic infarcts with a short T1 in the cerebellum and basal ganglia. We carried out repeat MRI on 12 patients with infarcts in the cerebellum or basal ganglia with a short T1. Cerebellar cortical lesions showed high signal on T1-weighted spin-echo images beginning at 2 weeks, wh...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s002349900242

    authors: Komiyama M,Nakajima H,Nishikawa M,Yasui T

    更新日期:2000-07-01 00:00:00

  • Labyrinthine enhancement on 3D black blood MR images of the brain as an imaging biomarker for cisplatin ototoxicity in (lung) cancer patients.

    abstract:PURPOSE:Cancer patients treated with platinum-based chemotherapy can present with ototoxicity symptoms. The purpose of this work is to report the imaging features related to cisplatin ototoxicity. METHODS:Between December 2015 and March 2019, a cohort of 96 consecutive patients with lung cancer was selected. Only pati...

    journal_title:Neuroradiology

    pub_type: 杂志文章

    doi:10.1007/s00234-020-02504-x

    authors: Veiga M,Kuhweide R,Demaerel V,De Pauw R,De Foer B,Casselman JW

    更新日期:2021-01-01 00:00:00