Abstract:
:Recent interest has focused on natural killer T (NKT) cells as effector cells in a possible new form of immunotherapy. NKT cells express T cell and natural killer cell receptors. They are CD1d-dependent and can be stimulated by alpha-galactosylceramide. We have studied peripheral blood levels of NKT cells simultaneously with CD8+ cells and natural killer cells in 54 patients with prostatic carcinoma. Levels of NKT cells in patients with androgen withdrawal and stable PSA levels were 211.8 +/- 138.4 cells/microl and in patients with rising PSA levels were 27.0 +/- 22.1 cells/microl. A similar but less pronounced difference in CD8+ cells between these groups was found (656.4 vs. 212.0 cells/microl). Comparing all 54 patients studied, a positive correlation was found between the levels of NKT cells and CD8+ cells (r = 0.83). Our results suggest an important and regulatory role of NKT cells in patients with prostatic carcinoma.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Schwemmer Bdoi
10.1159/000071836subject
Has Abstractpub_date
2003-01-01 00:00:00pages
146-9issue
2eissn
0042-1138issn
1423-0399pii
71836journal_volume
71pub_type
杂志文章abstract:OBJECTIVE:The objective of this study is to present the experience of 3 institutions performing renal autotransplantation (RAT) and to discuss surgical techniques employed and the results in the light of the medical literature. MATERIALS AND METHODS:A total of 14 patients (11 male and 3 female) with a mean age of 47 ±...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000448482
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:To develop risk predictive models of postpartum stress urinary incontinence (SUI) for both primiparous and multiparous women. MATERIALS AND METHODS:From July 2016 to July 2017, 815 singleton pregnant women without incontinence before pregnancy who were 18 years or older and admitted to 2 hospitals in Shenzh...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000508416
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:To determine whether diffusion-weighted magnetic resonance imaging (DWMRI), a noninvasive procedure, can contribute to the diagnosis of bladder pain syndrome/interstitial cystitis (BPS/IC). METHODS:The pelvic DWMRI of patients with chronic pelvic pain syndrome was selected between January 2012 and June 2017...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000493507
更新日期:2019-01-01 00:00:00
abstract::An unusual case of metastatic carcinoma of prostate, which presented as a huge abdominal mass and responded extremely well to endocrine therapy, is presented. The literature is reviewed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281205
更新日期:1986-01-01 00:00:00
abstract::In 47 patients with transitional cell carcinoma (TCC) of the bladder, we investigated the relationship between tissue laminin distribution and serum laminin levels. The results were compared with those obtained from 6 patients with pathologically proven normal bladder mucosa as well as those obtained previously from 5...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282440
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:Mini percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are well-established techniques with little morbidity. The combined use of standard PCNL and the mini-PCNL or the RIRS technique was evaluated and compared to investigate their own role in the management of staghorn calc...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000360708
更新日期:2015-01-01 00:00:00
abstract::We examined Southern blot analysis of genomic DNAs from 70 patients with sporadic renal cell carcinoma, using the human L-myc oncogene fragment as a hybridization probe. Our purpose was to study the relationship between the restriction fragment length polymorphism (RFLP) of the L-myc and the frequencies of metastasis....
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282261
更新日期:1991-01-01 00:00:00
abstract:AIM:Since DNA damage-related apoptosis is raising concerns regarding abnormal spermatogenesis, we investigated the changes in γ-H2AX during testicular germ cell apoptotic responses in the varicocele model. MATERIALS AND METHODS:Varicocele was induced by partial ligation of the left renal vein and animals were sacrific...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000316356
更新日期:2010-01-01 00:00:00
abstract:AIMS:To determine factors for treatment persistence in a real-life cohort of adult neurogenic lower urinary tract dysfunction. METHODS:We reviewed records of patients with neurogenic lower urinary tract dysfunction and mirabegron prescriptions. Exclusion criteria were indwelling urethral or suprapubic catheters and im...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000500349
更新日期:2019-01-01 00:00:00
abstract::The functional activity of the sphincter muscle of the urethra is known to be controlled largely by the hypogastric and pudendal nerves. It remains unknown, however, whether innervation of the muscle by these peripheral nerves is ipsi- or bilateral. In an attempt to answer this question urethral closure pressure was d...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281328
更新日期:1988-01-01 00:00:00
abstract::Inflammatory myofibroblastic tumors are commonly seen in young adults and adolescents and commonly present with painless hematuria. We report a case of a 38-year-old woman who presented to us with urinary retention due to a prolapsing tumor mass from the urethra, which was discovered to be an inflammatory myofibroblas...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000350516
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:We aimed to perform a multi-institutional study using a national database led by the Japanese Society of Endourology to investigate the effect of surgeon or hospital volume on the safety of robot-assisted radical prostatectomy (RARP). MATERIALS AND METHODS:Clinical data of 3,214 patients who underwent RAR...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000460304
更新日期:2017-01-01 00:00:00
abstract::We report on a 32-year-old man with a history of chronic lower abdominal pain and urogenital symptoms, leading to the diagnosis of coloseminal fistula complicating diverticular disease. We reviewed the literature on this rare clinical entity and would like to stress the role of pelvic imaging with rectal contrast to i...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000353351
更新日期:2014-01-01 00:00:00
abstract::Alternative minimally invasive methods treating benign prostate hyperplasia (BPH) have become more and more important. Transurethral needle ablation (TUNATM) has been demonstrated to be effective in both canine and the human prostate. The goal of our study was to prove the safety, feasibility and tolerance of this new...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章
doi:10.1159/000030298
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:This article describes our experience of using a totally extraperitoneal approach for endoscopic pelvic lymphadenectomy and inguinal hernia repair with the mesh technique in one procedure. MATERIALS AND METHODS:A total of 52 patients underwent modified pelvic lymph node dissection for the staging of prostate c...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000050938
更新日期:2001-01-01 00:00:00
abstract:UNLABELLED:BACKGROUND/AIMS/OBJECTIVES: To describe the depth of the laser coagulation zone in vivo based on histological examinations and the functional outcome of a 1,318-nm diode laser for enucleation in benign prostatic enlargement (BPE). METHODS:A total of 20 patients with BPE were treated by laser Eraser® enuclea...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000353554
更新日期:2013-01-01 00:00:00
abstract::Sex-dependent stone formation following portacaval shunt (PCS) was investigated in 82 male and 71 female Sprague-Dawley rats. 72.6% of male PCS rats and none of the female PCS rats developed urolithiasis, in 90.2%, potassium-hydrogen-urate stones formed. Hormonal analysis revealed significant alterations in steroid ho...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282544
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:Whereas the excellent functional outcomes after Holmium laser enucleation of the prostate (HoLEP) and its equivalency to open prostatectomy (OP) have been studied in detail in the past years, the oncological equivalency has yet to be investigated. Therefore, we conducted a matched pair analysis to evaluate...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000492923
更新日期:2018-01-01 00:00:00
abstract:AIM:To determine efficacy and clinical predictors of stone fragmentation when using slow-rate shock wave lithotripsy (SWL). PATIENTS AND METHODS:In total, 116 patients with radiopaque urinary tract stones were randomized into two groups: 57 patients were treated with SWL at 90 shocks/min, and 59 patients were treated ...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000106324
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To assess the role of primary open surgery versus the recommended combination approach (percutaneous and lithotripsy) to treat staghorn calculi in a developing country. PATIENTS AND METHODS:Available records (n = 91) of patients with staghorn managed during the last 4 years were retrieved. Patients were plac...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030456
更新日期:1999-01-01 00:00:00
abstract::In a combined (cross-sectional and longitudinal) study, the serum concentration of laminin P1 was measured by radioimmunoassay in 16 patients with benign inflammatory bladder disorders and 47 patients with transitional cell carcinoma of the bladder. The results were compared with the serum laminin P1 values in 50 heal...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282410
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVES:There is a considerable lack of consensus regarding indications and long-term efficacy of the many techniques for treating urinary stress incontinence. We report the long-term results of a modified pubovaginal sling procedure. METHODS:From 1989 to 1998, 129 consecutive patients underwent a pubovaginal sling...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000077685
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:When feasible, the treatment for all-invasive bladder cancer is radical cystectomy. The aim of the present study was to analyze the prognostic difference, disease-specific survival rate, of muscle-invasive transitional cell cancer of the bladder (TCCB) for progressive invasive TCCB. PATIENTS...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000107950
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to compare vesical and renal calcium oxalate crystalluria in an attempt to correlate crystal formation with chemical composition and calcium oxalate saturation of renal urine. MATERIAL AND METHODS:Urine specimens were directly collected from the bladder and the kidney, of 11 stone fo...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章
doi:10.1159/000030201
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:Immunotherapy effectively treats advanced renal cell carcinoma in only a limited number of patients. However, the predicted prognosis for each patient in relation to immune status and response to immunotherapy remains problematic. We analyzed tumor-infiltrating lymphocyte (TIL) subsets to determine whether...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000064361
更新日期:2002-01-01 00:00:00
abstract::This is the first report of urothelial carcinoma (UC) in a hemodialysis (HD) patient treated with almost the same doses of gemcitabine and paclitaxel (GP) as those administered to patients with normal renal function. There have been some reports of UC treated with cisplatin-based chemotherapy in HD patients. However, ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000327511
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Robot-assisted bladder diverticulectomy (RABD) through a technique for easier identification of diverticulum along with concomitant management of bladder outlet obstruction (BOO) utilizing a combination of transurethral prostatectomy (TUR-P) and photoselective vaporization of prostate (PVP) is presented. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000443799
更新日期:2016-01-01 00:00:00
abstract::Seventeen patients, age 1 day to 6 years with infantile polycystic kidney disease were evaluated with ultrasound and other imaging techniques. Most patients showed bilaterally enlarged kidneys with hyperechoic renal parenchyma, which had poor differentiation in outlines as well as between renal sinus, cortex and medul...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282303
更新日期:1992-01-01 00:00:00
abstract::A 33-year-old male presented to the Chiba University Hospital with the main complaint of right flank pain. Bilateral vas deferens were not palpable. Hormonal examination revealed hypergonadotropic hypogonadism and cytogenetic studies a 47,XXY karyotype. The significance of the association of this karyotype with the ab...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281703
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Augmentation cystoplasty is an effective approach to the detrusor hyperreflexia which is refractory to conservative treatment. Sporadic data have been published in patients with progressive diseases such as multiple sclerosis (MS). MATERIALS AND METHODS:Augmentation ileocystoplasty (Goodwin 'cup-patch') w...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000067708
更新日期:2003-01-01 00:00:00