Tissue effects resulting from eraser laser enucleation of the prostate: in vivo investigation.

Abstract:

UNLABELLED:BACKGROUND/AIMS/OBJECTIVES: To describe the depth of the laser coagulation zone in vivo based on histological examinations and the functional outcome of a 1,318-nm diode laser for enucleation in benign prostatic enlargement (BPE). METHODS:A total of 20 patients with BPE were treated by laser Eraser® enucleation of the prostate (ELEP). Prostatic tissue wedges were evaluated to assess the depth of the ELEP coagulation zones. Additionally, patients were assessed preoperatively and 12 months postoperatively. RESULTS:The coagulation zones were 0.36 ± 0.17 mm in epithelial tissue, 0.28 ± 0.15 mm in stromal tissue, and 0.25 ± 0.12 mm in mixed tissue. The coagulation area at the cutting edge completely sealed capillary vessels, reaching a depth of 0.35 ± 0.15 mm. The diameter of the coagulated vessels measured 1.75 ± 0.83 mm. Mean blood loss was 115.54 ± 93.12 ml, catheter time 1.35 ± 0.33 days, and hospital stay 1.89 ± 0.52 days. The International Prostate Symptom Score, maximal flow rate, and quality of life significantly improved 12 months after the procedure. CONCLUSIONS:ELEP is safe and effective for BPE treatment and yields good results at a follow-up of 1 year. Because of the limited penetration depth, damage to the urinary sphincter is not expected.

journal_name

Urol Int

journal_title

Urologia internationalis

authors

Lusuardi L,Hager M,Kloss B,Hruby S,Colleselli D,Zimmermann R,Janetschek G,Mitterberger M

doi

10.1159/000353554

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

391-6

issue

4

eissn

0042-1138

issn

1423-0399

pii

000353554

journal_volume

91

pub_type

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