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Lipids, lipoproteins and other coronary risk factors in Chinese male survivors of myocardial infarction.

Abstract：

OBJECTIVE:To assess the importance of an abnormal lipid profile as a risk factor in relation to non-biochemical risk factors, and to define the risk levels for lipid, lipoprotein and apolipoprotein in a Chinese population. PATIENTS AND METHODS:Serum lipids, lipoproteins, apolipoproteins and other cardiovascular risk factors were studied in 89 Chinese men 3 months after acute myocardial infarction and 56 controls. RESULTS:Cases had higher mean total cholesterol (TC), LDL- and VLDL-cholesterol, triglycerides and apolipoprotein B (Apo B), and lower mean HDL-cholesterol and apolipoprotein AI (Apo AI). Mean BMI was also higher, as was the prevalence of smokers and subjects with a history of hypertension. In univariate analysis, the odds ratios for TG > or = 1.6 mmol/l, LDL-cholesterol > or = 4.1 mmol/l, VLDL-cholesterol > or = 0.73 mmol/l, Apo B > or = 104 mg/dl were of the same order of magnitude as being a current smoker, having a BMI > or = 24.3 kg/m2, and a history of hypertension. High HDL-cholesterol (> or = 1.39 mmol/l) and Apo AI (> or = 139 mg/dl) were protective factors. The odds ratios for successively higher quartile values of cholesterol were not statistically significant. Multiple logistic regression identified smoking habit, history of hypertension, obesity, high Apo B and low Apo AI concentrations as independent risk factors for myocardial infarction. CONCLUSIONS:In a Chinese population, low serum Apo AI and high Apo B are risk factors for myocardial infarction of a comparable magnitude to smoking, hypertension and obesity.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Woo J,Ho SC,Wong SL,Woo KS,Tse CY,Chan KK,Kay CS,Mak WP,Cheung KO,Lam CW

doi

10.1016/0167-5273(93)90038-i

subject

Has Abstract,Author List Incomplete

pub_date

1993-06-01 00:00:00

pages

195-202

issue

3

eissn

0167-5273

issn

1874-1754

pii

0167-5273(93)90038-I

journal_volume

39

pub_type

杂志文章

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