Abstract:
:Transient DST non-suppression during disulfiram-treatment was fortuitously observed in a depressed patient. A disulfiram-potentiated DST (DSTd) was constructed by giving 800 mg disulfiram on the dexamethasone and postdexamethasone days. DST and DSTd were compared intraindividually in 21 patients and 14 controls. Disulfiram-potentiation was significant in constantly depressed patients, and in questionable controls due to possible subclinical depression or somatic factors which may cause 'false-positive' results. It did not occur in depressed patients during marked improvement or long-term recovery, and not in accurately screened controls. DSTd was significantly correlated with depression ratings, whereas DST was not.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Bergsholm P,Oulie D,Holsten F,Myking Odoi
10.1016/0165-0327(93)90059-ssubject
Has Abstractpub_date
1993-08-01 00:00:00pages
241-7issue
4eissn
0165-0327issn
1573-2517pii
0165-0327(93)90059-Sjournal_volume
28pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:Abnormalities in the glucose metabolism cause nervous and organic damage and are a cardiovascular risk factor. They could be a main cause for the increased morbidity and mortality rates found in patients with bipolar disorders. The exact prevalence of diabetes and pre-diabetic abnormalities, however, is not ...
journal_title:Journal of affective disorders
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更新日期:2016-01-01 00:00:00
abstract::Thirteen patients with major depressive disorder, 25 patients with dysthymia and 12 healthy controls underwent ergopsychometric testing. The effect of self-paced and set-paced load on mood, vigilance and perseveration tendency was recorded. Within the clinical groups, various types of load seemed to result mainly in v...
journal_title:Journal of affective disorders
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doi:10.1016/0165-0327(91)90095-a
更新日期:1991-10-01 00:00:00
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journal_title:Journal of affective disorders
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doi:10.1016/0165-0327(96)00037-7
更新日期:1996-09-09 00:00:00
abstract::Previous studies of illness onset in mania lack a frequency distribution for the interval between symptom onset and hospitalization (hospital latency), although a bimodal distribution of illness onset been suggested. We identified 100 patients hospitalized for mania and found a unimodal distribution, with mean +/- SD ...
journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
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更新日期:2005-12-01 00:00:00
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journal_title:Journal of affective disorders
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更新日期:2016-01-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.12.024
更新日期:2014-03-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.05.043
更新日期:2015-09-15 00:00:00
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journal_title:Journal of affective disorders
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doi:10.1016/j.jad.2018.06.023
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journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2014.08.044
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journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
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更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Psychotic major depression (PMD) and delusional misidentification syndromes (DMS) exhibit cognitive deficits. Since the P300 component of event-related potentials (ERPs) provides valuable information concerning cognition, we studied this component of ERPs in DMS and PMD patients. METHODS:Nine patients with ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/S0165-0327(03)00136-8
更新日期:2004-08-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2018-04-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.04.046
更新日期:2014-08-01 00:00:00
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journal_title:Journal of affective disorders
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doi:10.1016/j.jad.2015.05.020
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Socioeconomic status, as measured by education, occupation or income, is associated with depression. However, data are lacking on the psychosocial, material and behavioral mediators of these associations. We have examined the association of education, occupation and income with depression and the potential m...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.08.077
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Depression is the most prevalent psychiatric disorder in the elderly and several studies indicate that 10-15% of persons over 65 years suffer from significant depressive symptoms. Despite the high prevalence, most cases of depression in the elderly remain unrecognized and untreated, maybe because of a differ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00245-7
更新日期:2001-05-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
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更新日期:2019-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.11.015
更新日期:2013-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.jad.2012.10.010
更新日期:2013-05-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.08.030
更新日期:2013-12-01 00:00:00
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journal_title:Journal of affective disorders
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doi:10.1016/j.jad.2020.04.007
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.11.045
更新日期:2013-05-15 00:00:00
abstract:BACKGROUND:Major depression (MD) results from a complex synergy between genetic and environmental factors. The aim of this study is to analyze the interaction of tryptophan hydroxylase 2 gene (TPH2) variation and negative life events in the pathogenesis of MD. Three TPH2 polymorphisms, -703G/T (rs4570625), -473T/A (rs1...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.07.041
更新日期:2015-12-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2009-03-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究
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更新日期:2008-02-01 00:00:00
abstract::The nature and structure of posttraumatic stress disorder (PTSD) has been the subject of much interest in recent times. This research has been represented by two streams, the first representing a substantive body of work which focuses specifically on the factor structure of PTSD and the second exploring PTSD's relatio...
journal_title:Journal of affective disorders
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