Partial unilateral lentiginosis.

abstract：:During 1 year of continuous suppressive therapy for frequent recurrent genital herpes, about 44% of patients taking 400 mg acyclovir twice a day had no recurrences and 4% of patients taking placebo had no recurrences (i.e., fewer patients taking acyclovir had recurrences, and when they did there were fewer recurrences...

journal_title：Journal of the American Academy of Dermatology

authors： Conant MA

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:A number of factors other than those identified by the American Joint Committee on Cancer (AJCC) may have prognostic significance in the evaluation of melanoma. OBJECTIVE:We sought to evaluate commonly recorded clinical features potentially associated with aggressive melanoma. METHODS:We conducted a retros...

journal_title：Journal of the American Academy of Dermatology

authors： Donahue T,Lee CY,Sanghvi A,Obregon R,Sidiropoulos M,Cooper C,Merkel EA,Yélamos O,Ferris L,Gerami P

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Hereditary palmoplantar keratoderma (HPPK), type papulosa, is rare, and epidemiologic data are sporadic and inconsistent. An epidemiologic population study of this disease has not been performed previously. OBJECTIVE:We performed a large population study on prevalence of HPPK, type papulosa, in Croatia. ME...

journal_title：Journal of the American Academy of Dermatology

authors： Stanimirović A,Kansky A,Basta-Juzbasić A,Skerlev M,Beck T

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma, typically presents in middle-aged to elderly individuals. OBJECTIVE:We sought to study the demographics, clinicopathologic features, treatment response, and prognosis of patients with biopsy-proven MF diagnosed before 20 years of age...

journal_title：Journal of the American Academy of Dermatology

authors： Boulos S,Vaid R,Aladily TN,Ivan DS,Talpur R,Duvic M

更新日期：2014-12-01 00:00:00

abstract：:Disseminated superficial actinic porokeratosis (DSAP) is associated with sun exposure and tanning bed usage and has been rarely reported in association with systemic PUVA. We report the first case of DSAP occurring after topical foot PUVA. ...

journal_title：Journal of the American Academy of Dermatology

authors： Allen AL,Glaser DA

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Dengue fever is the most common identifiable cause of acute febrile illness among travelers returning from South America, South Central Asia, Southeast Asia, and the Caribbean. Although the characteristic exanthem of dengue fever occurs in up to 50% of patients, few descriptions of it are found in the dermat...

journal_title：Journal of the American Academy of Dermatology

authors： Pincus LB,Grossman ME,Fox LP

更新日期：2008-02-01 00:00:00

abstract：:Recent advances in our basic understanding of immunology, specifically the roles of various cell types involved in immune response and the action of cytokines they produce, has radically changed our understanding of the origin of inflammatory dermatoses, and other autoimmune diseases. Broadened comprehension of the im...

journal_title：Journal of the American Academy of Dermatology

authors： Nickoloff BJ,Stevens SR

更新日期：2006-03-01 00:00:00

abstract：:Human papillomavirus infection is one of the most common and most distressing cutaneous diseases in patients with HIV infection. It is also a common, and often therapeutically challenging, infection in individuals who are immunologically competent. A wide range of therapeutic options exists for treating cutaneous huma...

journal_title：Journal of the American Academy of Dermatology

authors： Kottke MD,Parker SR

更新日期：2006-09-01 00:00:00

abstract：:A group of 420 neonates underwent total cutaneous and oral mucosal examinations during the first week of life. Skin lesions were seen in almost every baby (99.3%). The eight most common dermatoses were desquamation (65.0%), Epstein's pearls (56.0%), sebaceous hyperplasia (48.0%), milia (36%), toxic erythema (34.8%), s...

journal_title：Journal of the American Academy of Dermatology

authors： Rivers JK,Frederiksen PC,Dibdin C

更新日期：1990-07-01 00:00:00

abstract：:Dermatologists frequently are consulted by a pregnant patient or a woman of childbearing age who desires acne therapy. Because there are no published studies in which women took acne medications throughout pregnancy, information about safety must be obtained indirectly from studies in which the agents were taken for a...

journal_title：Journal of the American Academy of Dermatology

authors： Rothman KF,Pochi PE

更新日期：1988-09-01 00:00:00

abstract：:Most clinicians agree that mycosis fungoides is the prototypic cutaneous T cell lymphoma. However, certain clinical characteristics indicate that this disorder may begin as a reactive rather than a neoplastic process. The concept of a nonneoplastic etiopathogenesis of mycosis fungoides is further supported by recent d...

journal_title：Journal of the American Academy of Dermatology

authors： Thiers BH

更新日期：1982-07-01 00:00:00

abstract：:Arthropod bites remain a major cause of patient morbidity. These bites can cause local or systemic effects that may be infectious or inflammatory in nature. Arthropods, notably insects and arachnids, are vectors of potentially serious ailments including malaria, West Nile virus, dengue, and Lyme disease. Measures to c...

journal_title：Journal of the American Academy of Dermatology

authors： Katz TM,Miller JH,Hebert AA

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Mycophenolate mofetil (MMF) has enjoyed increasing popularity as an emerging immunosuppressant treatment for various autoimmune dermatologic conditions, including pyoderma gangrenosum (PG). OBJECTIVE:The aim of this study was to examine the efficacy and safety of MMF as used in PG. METHODS:A retrospective ...

journal_title：Journal of the American Academy of Dermatology

authors： Li J,Kelly R

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Often after biopsy a skin cancer appears to resolve clinically and a repeat biopsy may be done on the area in question before proceeding with further treatment. OBJECTIVE:Our purpose was to assess the value of a subsequent biopsy in the treatment of skin cancers previously diagnosed by biopsy results. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Torres A,Seeburger J,Robison D,Glogau R

更新日期：1992-07-01 00:00:00

abstract：:Isotretinoin is most effective for patients with acne who fail to respond to other forms of treatment; virtually all patients respond to isotretinoin, 0.5 to 1.0 mg/kg/day. As many as 61% of patients are cured after one course, but 39% require further isotretinoin (16%) or oral antibiotics (23%). The relapse rate can ...

journal_title：Journal of the American Academy of Dermatology

authors： Layton AM,Cunliffe WJ

更新日期：1992-12-01 00:00:00

abstract：:A 60-year-old man with postpolycythemic myeloid metaplasia developed acute neutrophilic dermatosis (Sweet's syndrome), which responded to systemic steroid therapy. Six months later he developed acute myelogenous blast crisis refractory to leukemic induction therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Horan MP,Redmond J,Gehle D,Dabe IB,Fort SL

更新日期：1987-02-01 00:00:00

abstract：:Verruciform xanthomas occur on mucocutaneous surfaces and are characterized by hyperkeratosis, acanthosis, and the occurrence of "foam cells" stuffed with lipid surrounding capillaries in the dermis between rete pegs. Ultrastructural examination of a lesion on the penis revealed the presence of melanocytes with many l...

journal_title：Journal of the American Academy of Dermatology

authors： Balus S,Breathnach AS,O'Grady AJ

更新日期：1991-05-01 00:00:00

abstract：:Melasma is an acquired brown hypermelanosis of the face. Although it is thought that melasma is associated with multiple etiologic factors (pregnancy, gastric, racial, and endocrine), one of the primary causes of its exacerbation appears to be exposure to sunlight. Three patterns of melasma are recognized clinically: ...

journal_title：Journal of the American Academy of Dermatology

authors： Sanchez NP,Pathak MA,Sato S,Fitzpatrick TB,Sanchez JL,Mihm MC Jr

更新日期：1981-06-01 00:00:00

abstract：:The presence of immunoglobulin and complement deposits in the skin of three patients with papular urticaria suggests that these lesions may be due to a cutaneous vasculitis. These deposits were most frequently found in biopsy specimens taken from lesions within 24 hours of their development. The presence of granular d...

journal_title：Journal of the American Academy of Dermatology

authors： Heng MC,Kloss SG,Haberfelde GC

更新日期：1984-06-01 00:00:00

abstract：:We describe a 4-year-old, otherwise healthy boy with a congenital history of a perioral and labial segmental café-au-lait macule, who was noted to have unilateral localized gingival hyperpigmentation that aligned with the café-au-lait macule. This case is highly illustrative of the embryologic timing of the genetic ev...

journal_title：Journal of the American Academy of Dermatology

authors： Sergay A,Silverberg NB

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Inability of topical medications to penetrate via nail plate brings a great challenge to clinicians in treating onychomycosis. Furthermore, oral medications are not appropriate for all patients because of drug interactions, adverse effects, and contraindications. OBJECTIVE:We sought to evaluate the clinical...

journal_title：Journal of the American Academy of Dermatology

authors： Bhatta AK,Keyal U,Huang X,Zhao JJ

更新日期：2016-05-01 00:00:00

abstract：:New and relatively old types of vascular (capillary) proliferations in the skin have been described or better categorized in the last few years. They include reactive angioendotheliomatosis, acroangiodermatitis (pseudo-Kaposi sarcoma), diffuse dermal angiomatosis, intravascular histocytosis, glomeruloid angioendotheli...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：2003-11-01 00:00:00

abstract：:Hyperpigmentation, pulmonary infiltration, and erythema nodosum occurred in a patient receiving long-term minocycline therapy. Bronchoalveolar lavage revealed both a neutrophilic and an eosinophilic alveolitis. The pulmonary and systemic symptoms promptly resolved after discontinuation of minocycline. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bridges AJ,Graziano FM,Calhoun W,Reizner GT

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:The eruptive appearance of numerous seborrheic keratoses, the sign of Leser-Trélat, has been regarded as a reliable cutaneous marker of internal malignancy. OBJECTIVE:We have evaluated the possible association of malignant disease and the sign in 1752 consecutive cases of seborrheic keratoses. METHODS:Firs...

journal_title：Journal of the American Academy of Dermatology

authors： Lindelöf B,Sigurgeirsson B,Melander S

更新日期：1992-06-01 00:00:00

abstract：:As summarized in the first article in this continuing medical education series, the currently available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic disease. Emerging data also suggest associations between psoriasis and other comorbidities beyond psoriatic arthritis, including chr...

journal_title：Journal of the American Academy of Dermatology

authors： Takeshita J,Grewal S,Langan SM,Mehta NN,Ogdie A,Van Voorhees AS,Gelfand JM

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Erythema induratum of Bazin is a mostly lobular panniculitis. There is considerable controversy in the literature about whether or not vasculitis is a histopathologic requirement to establish the diagnosis of erythema induratum of Bazin. Even accepting vasculitis as a histopathologic criterion, there is no a...

journal_title：Journal of the American Academy of Dermatology

authors： Segura S,Pujol RM,Trindade F,Requena L

更新日期：2008-11-01 00:00:00

abstract：:Good to excellent clinical results have been obtained in the treatment of severe inflammatory acne (acne conglobata, acne fulminans, and acne conglobata with hidradenitis and dissecting cellulitis of the scalp) with orally administered isotretinoin (13-cis-retinoic acid). Similar promising results have been obtained i...

journal_title：Journal of the American Academy of Dermatology

authors： Plewig G,Nikolowski J,Wolff HH

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Increasing incidence and mortality rates from cutaneous melanoma are a major public health concern. As part of a national effort to enhance early detection of melanoma/skin cancer, the American Academy of Dermatology (AAD) has sponsored an annual education and early detection program that couples provision o...

journal_title：Journal of the American Academy of Dermatology

authors： Koh HK,Norton LA,Geller AC,Sun T,Rigel DS,Miller DR,Sikes RG,Vigeland K,Bachenberg EU,Menon PA,Billon SF,Goldberg G,Scarborough DA,Ramsdell WM,Muscarella VA,Lew RA

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Clusters of rare cylindroma or spiradenoma tumors are a recurrent clinical presentation, yet conventional genetic testing results in individuals with these tumors are frequently normal. OBJECTIVE:To determine if genetic mosaicism accounts for such cases. METHODS:A study of 6 cases from a series of 55 patie...

journal_title：Journal of the American Academy of Dermatology

authors： Arefi M,Wilson V,Muthiah S,Zwolinski S,Bajwa D,Brennan P,Blasdale K,Bourn D,Burn J,Santibanez-Koref M,Rajan N

更新日期：2019-12-01 00:00:00