Abstract：
:This study sought to determine possible causal linkages among stressful life events, social rhythms, and levels of depressive symptomatology for 81 elderly subjects (51 recently widowed, 30 healthy controls). We examined the associations among stressful life events (i.e., bereavement status at baseline or a severely threatening event occurring between baseline and followup), social rhythm stability, and the level of depressive symptoms. Results indicated that while stressful life events were not associated with significant changes in social rhythm stability, social rhythm stability was a significant negative correlate of both baseline and followup levels of depressive symptomatology; that is, lower levels of social rhythm stability at baseline were associated with high levels of depressive symptoms at baseline (rho = -0.33, n = 81, p < 0.001) and at followup (rho = -0.23, n = 81, p < 0.05). Bereavement was also a significant positive correlate of depressive symptomatology both at baseline (rho = 0.79, n = 81), p < 0.0001) and at followup (rho = 0.55, n = 81, p < 0.0001). It is likely that future research will benefit from social rhythm assessment obtained temporally closer to major life events and from the use of structured interviews to ascertain the presence of syndromal major depression at followup as well as the inclusion of subjects with a wider range of functional impairments. Nevertheless, these results represent a first step in disentangling possible causal connections among stressful life events, social rhythms, and depressive symptomatology.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Prigerson HG,Reynolds CF 3rd,Frank E,Kupfer DJ,George CJ,Houck PRdoi
10.1016/0165-1781(94)90045-0subject
Has Abstractpub_date
1994-01-01 00:00:00pages
33-49issue
1eissn
0165-1781issn
1872-7123pii
0165-1781(94)90045-0journal_volume
51pub_type
杂志文章abstract：:Memory and symptomatology were examined as predictors of social skill acquisition in psychiatric inpatients participating in a social skills training program. Poor memory was related to pretreatment social skill impairments and slower rates of skill improvement during the intervention for patients with schizophrenia o...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(91)90064-v
更新日期：1991-06-01 00:00:00
abstract：:Tourette syndrome (TS) is a heritable disorder characterized by tics that are decreased in some patients by treatment with alpha adrenergic agonists and dopamine receptor blockers. Thus, this study examines the relationship between catecholamine gene expression in blood and tic severity. TS diagnosis was confirmed usi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.04.034
更新日期：2012-12-30 00:00:00
abstract：:Bipolar disorder has the highest suicide attempt rate among psychiatric disorders. Many factors are associated with the risk of suicide attempt in patients with type 1 bipolar disorder, but the relation between them has still not been explicitly stated. This study aimed to examine the predictability of suicide attempt...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.04.012
更新日期：2019-05-01 00:00:00
abstract：:Religion and/or spirituality (R/S) can play a vital, multifaceted role in mental health. While beliefs about God represent the core of many psychiatric patients' meaning systems, research has not examined how internalized images of the divine might contribute to outcomes in treatment programs/settings that emphasize m...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.05.003
更新日期：2017-08-01 00:00:00
abstract：:This study test the effects on autonomic nervous system (ANS) activity of two doses (0.25 mg/kg and 0.50 mg/kg) of dextroamphetamine in normal men. Skin conductance and heart rate were recorded during rest, tone presentation, and a reaction time task. Compared to placebo, dextroamphetamine increased both skin conducta...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/0165-1781(81)90006-8
更新日期：1981-02-01 00:00:00
abstract：:High rates of psychiatric impairment in adults with 22q11 deletion syndrome (22q11DS, also referred to as DiGeorge or velocardiofacial syndrome) suggest that behavioral trajectories of children with 22q11DS may provide critical etiologic insights. Past findings that report Diagnostic and Statistical Manual (DSM) diagn...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.03.023
更新日期：2009-03-31 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2015.06.005
更新日期：2015-08-30 00:00:00
abstract：:The association between cognitive performance and general functioning in depression is controversial. The present study evaluated the association between cognitive dysfunction and major depressive disorder (MDD, N=70) as compared with age- and gender-matched healthy controls (n=206) and its relationship to general fun...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.12.001
更新日期：2010-04-30 00:00:00
abstract：:In schizophrenia, psychomotor slowing and stereotypy are poorly delineated from cognitive deficits like diminished processing speed. Inpatients' performance outcomes on a line-copying task, a task assessing stereotypy and a processing-speed task are compared. Results suggested that psychomotor slowing and stereotypy a...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.01.017
更新日期：2008-10-30 00:00:00
abstract：:Voxel-based morphometry (VBM) is an objective whole-brain technique for characterizing regional cerebral volume and tissue concentration differences in structural magnetic resonance images. In the current study, we used VBM to examine possible cerebral gray matter abnormalities in patients with posttraumatic stress di...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2005.09.006
更新日期：2006-01-30 00:00:00
abstract：:Both major depressive disorders (MDD) and schizophrenia (SZ) have been associated with reductions in slow-wave (Stages 3 and 4) sleep, although these findings are controversial. The present study compared quantitative EEG measures of slow-wave activity (0.5-4 Hz) during non-REM (NREM) sleep among age-matched, symptoma...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(00)00181-5
更新日期：2000-09-11 00:00:00
abstract：:It is not only unclear why hallucinations in schizophrenia occur with different prevalence by modality, but also to what extent they do. Reliable prevalence estimates of hallucinations by modality in schizophrenia are currently lacking, particularly for non-auditory hallucinations. Studies have also tended to report l...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.01.102
更新日期：2017-06-01 00:00:00
abstract：:Both psychiatric disorders and psychiatric drug treatments produce changes of psychomotor performance which can disturb and/or interfere with the ability to drive safely. We studied the influence of current psychiatric drug treatments on psychomotor functions and on driving performance of 77 consecutive psychiatric ou...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2009.02.013
更新日期：2010-04-30 00:00:00
abstract：:Childhood maltreatment history is a prevalent risk factor for substance use disorder and has lifelong adverse consequences on psychiatric wellbeing. The role of personality variations in determining childhood maltreatment-associated outcomes is poorly understood. This study sought to test neuroticism and agreeableness...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.07.010
更新日期：2018-10-01 00:00:00
abstract：:Catechol-O-methyltransferase (COMT) is a candidate gene for the pathogenesis of some psychiatric disorders. The aim of this study is to examine the role of the COMT gene Val158Met polymorphism on the clinical aspects of bipolar disorder including symptomatology and therapeutic response. This study comprised 144 unrela...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.psychres.2008.09.011
更新日期：2010-01-30 00:00:00
abstract：:Predicting the outcome of antidepressant treatment by pre-treatment features would be of great usefulness for clinicians as up to 50% of major depressives may not have a satisfactory response in spite of adequate trials of antidepressant drugs. In the present article we compared a linear multivariate model of predicto...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.07.009
更新日期：2007-08-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.11.038
更新日期：2019-01-01 00:00:00
abstract：:Determining meaningful activation thresholds in functional magnetic resonance imaging (fMRI) paradigms is complicated by several factors. These include the time-series nature of the data, the influence of physiological rhythms (e.g. respiration) and vacillations introduced by the experimental design (e.g. cueing). We ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(97)00024-3
更新日期：1997-08-08 00:00:00
abstract：:General practitioners (GP), on the frontline for individuals with mental health problems, often deal with work-related common psychiatric disorders. We aimed to determine the prevalence of work-related common psychiatric disorders in general practice and associated patients' and GPs' characteristics. HERACLES, a cross...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.09.008
更新日期：2018-01-01 00:00:00
abstract：:Schizophrenia is considered a neurodevelopmental disorder, but whether the adolescent period, proximal to onset, is associated with aberrant development in individuals at clinical high risk (CHR) for psychosis is incompletely understood. While abnormal gray and white matter development has been observed, alterations i...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2013.08.004
更新日期：2014-01-30 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(92)90001-k
更新日期：1992-08-01 00:00:00
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.05.088
更新日期：2015-08-30 00:00:00
abstract：:Social cognition refers to a set of cognitive abilities that allow us to perceive and interpret social stimuli. Social cognition is affected in schizophrenia and impairments have also been documented in unaffected relatives, suggesting that social cognition may be related to a genetic vulnerability to the disease. Thi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.07.055
更新日期：2014-12-15 00:00:00
abstract：:A comprehensive study was conducted 8 months after the 2010 Yushu earthquake to assess the prevalence of posttraumatic stress disorder (PTSD) among medical rescuers and the rescuers' quality of life. Additionally, the study examines differences between local and supporting forces, as well as the relationship between P...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.09.047
更新日期：2015-12-15 00:00:00
abstract：:Schizophrenia patients have well-established deficits in facial emotion perception, which contribute to their poor social functioning. A number of studies have related these deficits to a differential dysfunction in the magnocellular (M) versus parvocellular (P) visual pathway. We assessed 35 schizophrenia patients an...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.03.031
更新日期：2017-07-01 00:00:00
abstract：:This study aimed to assess stigma and its sociodemographic and clinical correlates among patients with bipolar disorder while in remission. 185 patients currently in remission were assessed on Internalized Stigma of Mental Illness Scale (ISMIS) for internalized stigma, Explanatory Model Interview Catalogue Stigma Scal...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.07.012
更新日期：2016-10-30 00:00:00
abstract：:Imaging studies in patients with Type II alcohol dependence have revealed significant reductions in dopamine (DA) D2 receptor availability. Here we assessed the effects of alcohol detoxification in DA D2 receptors in alcoholic subjects. We evaluated 14 patients with Type II alcohol dependence tested within 6 weeks of ...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/s0925-4927(02)00087-2
更新日期：2002-12-30 00:00:00
abstract：:Orexins have played a role in reward-seeking and addiction-related behavior. There are few reports in the literature on serum levels of orexins in patients with heroin use disorder (HUD) undergoing methadone maintenance treatment (MMT). The aim of this study was to investigate the serum levels of orexin A in HUD patie...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.010
更新日期：2018-06-01 00:00:00
abstract：:Biopterin, neopterin and the large neutral amino acids (LNAA), i.e. phenylalanine, tyrosine, tryptophan, isoleucine, leucine and valine were measured in plasma of 20 severely depressed inpatients before and after a course of electroconvulsive therapy (ECT). These patients showed a significantly lower plasma biopterin ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(01)00282-7
更新日期：2001-09-20 00:00:00
abstract：:Semantic disturbances have been proposed as a possible cause of formal thought disorder in schizophrenia. Fluency tasks, in which volunteers are asked to produce as many exemplars as they can for a given category during one minute, are usually applied to the assessment of semantic processing. However, studies associat...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.11.074
更新日期：2019-01-01 00:00:00
