Abstract:
:In keeping with current interest in bactericidal effects of lasers to treat localized infection, we examined the effect of CO2 laser light on three bacterial species. Cell monolayers were placed atop filters minimizing the presence of extracellular water. Samples were exposed to irradiance values between 0 and 520 W/cm2 for 0.1 s. Cell survival was determined by colony counts. There was logarithmic killing of the bacteria with increasing irradiance; 90% kill was effected at 180 W/cm2 for Escherichia coli, 350 W/cm2 for Streptococcus mutans, and 250 W/cm2 for Bacillus stearothermophilus. However, standard deviations suggest no significant difference between cell types. Our results show the bactericidal effect of the CO2 laser with no remarkable difference between Gram types. However, substantial cell kill was achieved at relatively low irradiance. Whereas selectivity of damage may not be afforded by the CO2 laser, it may minimize collateral damage.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Talebzadeh N,Morrison PR,Fried MPdoi
10.1002/1096-9101(1994)14:2<164::aid-lsm1900140209subject
Has Abstractpub_date
1994-01-01 00:00:00pages
164-7issue
2eissn
0196-8092issn
1096-9101journal_volume
14pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVE:Verteporfin is a new photosensitizer with short-term skin photosensitivity. The objective of this preclinical study was to find the light dose that effectively ablates canine esophageal mucosa when delivered 30 minutes after Verteporfin injection. STUDY DESIGN/MATERIALS AND METHODS:Verteporfin...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.10014
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The recently introduced Er:YAG laser seems to be a promising alternative in periodontal treatment due to its thermo-mechanical ablation mechanism. The present study attempted to compare the effects of an Er:YAG laser on periodontally involved root surfaces at different power settings in vivo an...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
doi:10.1002/lsm.1125
更新日期:2001-01-01 00:00:00
abstract::This article reviews the principle uses of ophthalmic lasers, providing historical background with an emphasis on new applications and areas of investigation. Ophthalmic photocoagulation was the first medical laser application and has restored or maintained vision in millions of people. More recently, photodisruption ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,评审
doi:10.1002/lsm.1900170203
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Er:YAG laser has been used for caries removal and cavity preparation, using ablative parameters. Its effect on the margins of restorations submitted to cariogenic challenge has not yet been sufficiently investigated. The aim of this study was to assess the enamel adjacent to restored Er:YAG la...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
doi:10.1002/lsm.20684
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The argon laser-assisted vascular anastomosis may solve the problems of conventional sutured anastomosis, such as vascular stenosis and arrest of growth owing to a foreign-body reaction to suture material. STUDY DESIGN/MATERIALS AND METHODS:Twelve argon laser-assisted vascular anastomoses, se...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900160105
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Laser-assisted treatment of tattoos is well recognized to produce opaque epidermal whitening that prevents multiple sequential passes during a single treatment session. The amount of epidermal whitening produced in association with the procedure can be minimized by topical application of perflu...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
doi:10.1002/lsm.22659
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Many studies have investigated the application of micro-insulated needles with radio frequency (RF) to treat acne in humans; however, the use of a micro-insulated needle RF applicator has not yet been studied in an animal model. The purpose of this study was to evaluate the effectiveness of a ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22599
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Basal cell carcinoma (BCC) is an indolent form of skin cancer that is rarely life threatening, but can cause significant cosmetic and functional morbidity. Surgical treatments often result in disfiguring scars, while topical therapies frequently result in recurrence. The need for a more effecti...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22803
更新日期:2018-02-13 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Despite laser applications targetted toward tonsillar tissue, there has been no characterization of underlying optical and thermal events during laser irradiation of tonsillar tissue. STUDY DESIGN/MATERIALS AND METHODS:The optical properties of canine and human tonsils were determined at 805 n...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1055
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to examine the influence of implant bed preparation, using either Er:YAG laser ablation, piezoelectric surgery or drill osteotomy, on osseointegration of titanium dental implants after 4, 6, and 8 weeks. MATERIAL AND METHODS:A total of 108 implants (Camlog) were plac...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20944
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Acne scarring is a common complication of acne but no effective single treatment modality has been developed. To compare the efficacy of 1,550 nm Er:Glass fractional laser and chemical reconstruction of skin scar (CROSS) method in the treatment of acne scars. STUDY DESIGN/MATERIALS AND METHODS...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
doi:10.1002/lsm.20796
更新日期:2009-10-01 00:00:00
abstract::Hematoporphyrin derivative (HpD) is a photoactive, oncophilic substance that produces cutaneous photosensitivity as its only significant side effect. Twenty-three patients who received systemic HpD and the usual light-avoidance precautions were studied prospectively to determine the incidence and severity of cutaneous...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900080312
更新日期:1988-01-01 00:00:00
abstract::Using an optically shielded fiber optic laser catheter, the amount of gas produced when firing an argon ion laser into 0.9% saline solution or blood alone and into atheromatous aorta in either a blood or 0.9% saline medium was quantitated. Energies from 0.25 to 4 joules (J) were used at powers of 2, 5, and 8 W. We fou...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900080113
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Intravascular ultrasound (IVUS) has been used successfully to detect intravascular lesions. This study evaluates the ability of IVUS to detect acoustic damage to the arterial wall following high power, pulsed laser ablation. STUDY DESIGN/MATERIALS AND METHODS:Arterial ablation and disruption w...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900160205
更新日期:1995-01-01 00:00:00
abstract::The author's experience in the use of the argon laser in the treatment of superficial vascular lesions in children is reviewed. Deteriorating portwine stains, strawberry hemangiomas, other hemangiomas, telangiectasias, and other lesions are discussed. Their natural histories are discussed. Details are given regarding ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900060106
更新日期:1986-01-01 00:00:00
abstract::Since the first use of lasers in ophthalmology in the early 1960s, applications for the medical laser have been found in many medical specialties. Despite their increasing usefulness, lasers have been reported to induce injuries. Few studies have tried to quantify the number of injuries caused by the clinical use of l...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900070603
更新日期:1987-01-01 00:00:00
abstract::Assessments of non-surgical office-based aesthetic treatments' efficacy including lasers are mostly based on subjective evaluation of clinical photography. Accumulating evidence suggest that non-invasive skin imaging such as optical coherence tomography (OCT) can be effectively used to assess not only the skin surface...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,评审
doi:10.1002/lsm.23219
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Helicobacter pylori (HP) is an endemic pathogenic bacterium causing gastritis and gastroduodenal ulceration in humans and is linked to the development of gastric malignancies. These first human in vivo studies investigated the photoeradication of HP using laser and white light. STUDY DESIGN/M...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
doi:10.1002/lsm.10066
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Ovarian cancer remains the deadliest malignancy of the female reproductive system. The ability to identify and destroy all ovarian tumor nodules may have a termendous impact on preventing tumor recurrence, and patient survival. The objective of this study is to investigate the effectiveness of...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22269
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Enzyme histochemical stains of frozen sections have been used by investigators to assess thermal damage. The assessment of thermal damage to cells in lipid-rich tissues such as subcutaneous tissue and sebaceous glands can be difficult due to the quality of frozen sections of such tissues. The p...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20450
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In this study, methylene blue-mediated photodynamic therapy (MB-PDT) was used as a possible alternative method for the treatment of oral lichen planus (OLP). STUDY DESIGN/MATERIALS AND METHODS:Thirteen patients with 26 OLP lesions were enrolled in this study. Patients were instructed to gargl...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20278
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this clinical study was to evaluate the safety of local delivery of a photosensitizer followed by photodynamic therapy (PDT), to determine its effectiveness in reducing in-stent restenosis. STUDY DESIGN/PATIENTS AND METHODS:Porfimer sodium was administered via a local delivery cath...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20018
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of relatively novel approach of application of polychromatic light waves on flap survival of experimental musculocutaneous flap model and to investigate efficacy of this modality as a delay procedure to increase vascularization of zone 4 of transverse rectus ab...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.23063
更新日期:2019-08-01 00:00:00
abstract:INTRODUCTION:The pulsed dye laser (PDL) using varying fluences and pulse durations have been used to treat hemangiomas. This study aims to examine the efficacy and safety of the 595-nm PDL for the treatment of infantile hemangiomas using short (1.5-3 milliseconds) versus long (10 milliseconds) pulse durations and high ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.21159
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The Holmium: YAG (Ho: YAG) laser has been used for the ablation of prolapsed discs but alternative techniques are available, and this application remains controversial. It also has potential for the decompression of nerve roots within narrowed foraminae with the technique of endoscopic laser fo...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1083
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Enhancement of photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) has been demonstrated experimentally using light dose fractionation or CP94 iron chelation. This study extends this research. STUDY DESIGN/MATERIALS AND METHODS:In normal rat colon, CP94 administration and light dose f...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20328
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In the last decade, many different kinds of therapies have emerged as a consequence of advances in the field of applied technology. It is known that low level laser therapy contributes to tissue healing; however, the use of photodynamic therapy (PDT) in healing and the scar formation processes...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20062
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Pores in the sclera are a candidate pathway for aqueous transport and therefore can be utilized to decrease the intraocular pressure (IOP) in glaucomatous eyes. Since pore formation is a well-known mechanism for stress relaxation in solids, laser-induced creation of pores in cartilage increase...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22202
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To demonstrate that high color fidelity light-emitting diode (LED) sources are preferred by dermatologists for the evaluation of patients during standard-of-care, outpatient visits when compared to low color fidelity LED sources similar to fluorescent lighting. STUDY DESIGN/MATERIALS AND METH...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.23352
更新日期:2020-11-08 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Cosmeceuticals, chemical peels and collagen injections are used to rejuvenate skin, but none of these methods is effective or permanent. Recently, laser resurfacing has been found to be effective, but the incidence of side effects is relatively high. Two years ago, the non-ablative wrinkle red...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
doi:10.1002/lsm.10119
更新日期:2003-01-01 00:00:00