Growth hormone and parathyroid hormone stimulate intestinal calcium absorption in aged female rats.

abstract：:GHRH stimulates GH secretion in chickens as in mammals. However, nothing is known about the chicken GHRH receptor (GHRH-R). Here we report the cDNA sequence of chicken GHRH-R. Comparison of the cDNA sequence with the chicken genome localized the GHRH-R gene to chicken chromosome 2 and indicated that the chicken GHRH-R...

journal_title：Endocrinology

authors： Porter TE,Ellestad LE,Fay A,Stewart JL,Bossis I

更新日期：2006-05-01 00:00:00

abstract：:Explants from nonmenstrual endometria cultured in the absence of ovarian hormones undergo tissue breakdown. Addition of estradiol and progesterone (EP) prevents proteolysis. Explants include stromal and epithelial compartments which play different but complementary roles in endometrial physiology, including tissue rem...

journal_title：Endocrinology

authors： Gaide Chevronnay HP,Lemoine P,Courtoy PJ,Marbaix E,Henriet P

更新日期：2010-09-01 00:00:00

abstract：:Aprotinin caused a dose-dependent inhibition of [125I]hCG binding to its receptor in plasma membranes prepared from luteinized rat ovaries. Displacement of [125I]hCG from its receptor by aprotinin was temperature dependent, with an ID50 of 300 microM at 4 C and an ID50 of 3700 microM at 22 C. Equilibrium binding data ...

journal_title：Endocrinology

authors： Wilks JW,Hui OJ

更新日期：1987-03-01 00:00:00

abstract：:Thyroid cell growth and function are regulated by hormones and growth factors binding to cell surface receptors that are coupled via G proteins, Gs and Gq, to the adenylyl cyclase and phospholipase C signal transduction systems, respectively. Activating mutations of the TSH receptor and G alpha s have been documented ...

journal_title：Endocrinology

authors： Zeiger MA,Saji M,Gusev Y,Westra WH,Takiyama Y,Dooley WC,Kohn LD,Levine MA

更新日期：1997-08-01 00:00:00

abstract：:We have measured the concentrations of vasopressin in sequential samples of cerebrospinal fluid (CSF) obtained from fetal lambs between 108 and 130 days gestation. There was a clear and significant (F = 4.46; P less than 0.005) rhythm in vasopressin concentrations in the CSF of nine fetuses, characterized by a mean tr...

journal_title：Endocrinology

authors： Stark RI,Daniel SS

更新日期：1989-06-01 00:00:00

abstract：:Steroid hormone synthesis is a vital function of the adrenal cortex, serves a critical role in gonadal function, and maintains pregnancy if normally executed in the placenta. The substrate for the synthesis of all steroid hormones is cholesterol, and its conversion to the first steroid, pregnenolone, by the cholestero...

journal_title：Endocrinology

authors： Yivgi-Ohana N,Sher N,Melamed-Book N,Eimerl S,Koler M,Manna PR,Stocco DM,Orly J

更新日期：2009-02-01 00:00:00

abstract：:Prostaglandin (PG) E2 (PGE(2)) plays a central role in the regulation of smooth muscle contractions. Classically, PGE(2) stimulates contractions via EP1 and EP3 receptors, whereas EP2 and EP4 maintain quiescence. Labor involves a change from myometrial quiescence to contractions with a shift from anti- to proinflammat...

journal_title：Endocrinology

authors： Kandola MK,Sykes L,Lee YS,Johnson MR,Hanyaloglu AC,Bennett PR

更新日期：2014-02-01 00:00:00

abstract：:The specific uptake by rat liver of human (hGH) and bovine (bGH) GHs labeled with 125I was studied by an in vivo procedure. A significant reduction of the uptake was observed when labeled hormones were injected together with different amounts of the corresponding native GH. This reduction was dose dependent, and the c...

journal_title：Endocrinology

authors： Turyn D,Dellacha JM

更新日期：1978-10-01 00:00:00

abstract：:In seasonal species, various physiological processes including reproduction are organized by photoperiod via melatonin, but the mechanisms of melatonin action are still unknown. In birds, the peptide gonadotropin-inhibiting hormone (GnIH) has been shown to have inhibitory effects on reproductive activity and displays ...

journal_title：Endocrinology

authors： Revel FG,Saboureau M,Pévet P,Simonneaux V,Mikkelsen JD

更新日期：2008-03-01 00:00:00

abstract：:In order to delineate the ages of onset and decline in sensitivity to growth hormone (GH) in rats, the ability of ovine GH in vitro to stimulate amino acid uptake and protein synthesis was studied in diaphragm muscle. GH (25 mug/ml) produced a significant, but small (12-17%), stimulation of alpha-aminoisobutyric acid ...

journal_title：Endocrinology

authors： Nutting DF

更新日期：1976-05-01 00:00:00

abstract：:Despite the specificity inferred by its name, glycogen synthase kinase (GSK)-3beta is an important kinase with a plethora of significant cellular targets, including cytoskeletal proteins and transcription factors, and its activity is regulated by phosphorylation on tyrosine/serine residues. As part of our efforts to d...

journal_title：Endocrinology

authors： Liao X,Thrasher JB,Holzbeierlein J,Stanley S,Li B

更新日期：2004-06-01 00:00:00

abstract：:Although GH plays a key role in postnatal growth and differentiation, its role in fetal differentiation is not clear at the present. The aim of the present study was to investigate whether GH plays a role in fetal sexual differentiation, and we used in vitro organ culture assay of sexual differentiation to determine t...

journal_title：Endocrinology

authors： Nguyen AP,Chandorkar A,Gupta C

更新日期：1996-09-01 00:00:00

abstract：:Human livers, obtained from donors at the time of transplant, were homogenized in 0.25 M sucrose and fractionated by differential centrifugation. The specific binding of [125I] human (h) GH to total particulate fractions from 18 livers varied from 0.4-5.1% of the total radioactivity/100 micrograms protein. Binding aff...

journal_title：Endocrinology

authors： Hocquette JF,Postel-Vinay MC,Kayser C,de Hemptinne B,Amar-Costesec A

更新日期：1989-10-01 00:00:00

abstract：:We investigated the effect of TSH on calcium transport in mouse thyroid, as well as the influence of iodide thereupon. Thyroid lobes were incubated in Krebs-Ringer bicarbonate buffer containing [45Ca2+] and the time-dependent uptake of [45Ca2+] by the lobes was observed. In the presence of 0.5 mU/ml TSH, the uptake of...

journal_title：Endocrinology

authors： Hashizume K,Ichikawa K,Komiya I,Onaya T

更新日期：1984-05-01 00:00:00

abstract：:Cholera toxin (CT) injected ip on day 1 (day of ovulation) of the 4-day hamster estrous cycle, when circulatory progesterone is high and estrogen low, induced a massive uterine decidual reaction, a progesterone-dependent growth normally triggered by the implanting blastocyst. However, CT injected ip on day 3, when cir...

journal_title：Endocrinology

authors： Alleva JJ,Kenimer JG,Jordan AW,Lamanna C

更新日期：1983-06-01 00:00:00

abstract：:Primary functional bovine adrenal cortical cell cultures have been developed to study the factors controlling adrenal cell growth. Cells were prepared by the collagenase technique and maintained in F-12 medium containing fetal calf serum and horse serum. Cells contained abundant lipid as demonstrated by staining with ...

journal_title：Endocrinology

authors： Gospodarowicz D,Ill CR,Hornsby PJ,Gill GN

更新日期：1977-04-01 00:00:00

abstract：:The pattern of glucagon gene expression and the posttranslational processing of proglucagon was studied in the fetal and neonatal rat. Pancreatic immunoreactive glucagon (IRG) and glucagon-like immunoreactivity (GLI) were low in both fetal pancreas and intestine, respectively. Immediately after birth, pancreatic IRG r...

journal_title：Endocrinology

authors： Lee YC,Brubaker PL,Drucker DJ

更新日期：1990-11-01 00:00:00

abstract：:The present study was undertaken to evaluate the efficacy of an estradiol-chemical delivery system (E2-CDS) for the brain vs. estradiol benzoate (E2-BNZ) in suppressing serum testosterone (T) and weights of the ventral prostate and seminal vesicle in male rats. Also, the role of serum T in the weight reduction of andr...

journal_title：Endocrinology

authors： Anderson WR,Rahimy MH,Brewster ME,Bodor N,Simpkins JW

更新日期：1991-08-01 00:00:00

abstract：:Glucocorticoid (Gc) excess, from endogenous overproduction in disorders of the hypothalamic-pituitary-adrenal axis or exogenous medical therapy, is recognized to cause adverse metabolic side effects. The Gc receptor (GR) is widely expressed throughout the body, including brain regions such as the hypothalamus. However...

journal_title：Endocrinology

authors： Sefton C,Harno E,Davies A,Small H,Allen TJ,Wray JR,Lawrence CB,Coll AP,White A

更新日期：2016-11-01 00:00:00

abstract：:Because there are sex differences in feeding behavior in rats, we looked for a possible sex difference in the response to glucose of melanin-concentrating hormone (MCH) neurons in the lateral hypothalamic area using phosphorylated cAMP response element-binding protein (pCREB) as a marker of neural activity. Intact mal...

journal_title：Endocrinology

authors： Mogi K,Funabashi T,Mitsushima D,Hagiwara H,Kimura F

更新日期：2005-08-01 00:00:00

abstract：:Mesenchymal stem cells can differentiate into mature chondrocytes, osteoblasts, and adipocytes. Excessive and dysfunctional visceral adipocytes increase upon menopause and importantly contribute to altered metabolism in postmenopausal women. We previously showed both plasma membrane and nuclear estrogen receptors alph...

journal_title：Endocrinology

authors： Ahluwalia A,Hoa N,Ge L,Blumberg B,Levin ER

更新日期：2020-11-01 00:00:00

abstract：:Uterine ornithine decarboxylase (ODC) activity is reported to increase after estrogen administration to fetal, neonatal, immature, and adult rats, suggesting that it may be a useful marker in studies of the development of estrogen responsiveness. Standard conditions were validated for enzyme assay of uterine cytosols ...

journal_title：Endocrinology

authors： Olson ME,Sheehan DM,Branham WS

更新日期：1983-11-01 00:00:00

abstract：:Calcitonin (CT) and related peptides, such as CT gene-related peptide and salmon CT (sCT)-like peptide, are present in the rat nervous system and the pituitary gland, and sCT markedly inhibits basal and TRH-stimulated PRL release from anterior pituitary (AP) cells. Because TRH-induced PRL release is known to involve i...

journal_title：Endocrinology

authors： Shah GV,Kennedy D,Dockter ME,Crowley WR

更新日期：1990-08-01 00:00:00

abstract：:The existence of cytoplasmic estrogen receptors (ERs) has been reported in the guinea pig brain using immunocytochemical techniques. While cytoplasmic ERs have been reported recently in other species, such as opossum, musk shrew, and ferrets, an exclusively cell nuclear pattern of ER immunoreactivity has been reported...

journal_title：Endocrinology

authors： Blaustein JD

更新日期：1992-09-01 00:00:00

abstract：:The developmental patterns of thyroid-stimulating hormone (TSH) was examined in female Long-Evans rats by radioimmunoassay of pituitary and plasma from 5 through 80 days of age. The effects of hypothyroidism on normal TSH levels were examined in animals radiothyroidectomized at birth. Control animals showed a peak in ...

journal_title：Endocrinology

authors： Cons JM,Umezu M,Timiras PS

更新日期：1975-07-01 00:00:00

abstract：:Serum retinol-binding protein 4 (RBP4) levels are increased in insulin-resistant humans and correlate with severity of insulin resistance in metabolic syndrome. Quantitative Western blotting (qWestern) has been the most accurate method for serum RBP4 measurements, but qWestern is technically complex and labor intensiv...

journal_title：Endocrinology

authors： Yang Q,Eskurza I,Kiernan UA,Phillips DA,Blüher M,Graham TE,Kahn BB

更新日期：2012-03-01 00:00:00

abstract：:Angiotensin type 1 receptor blockers are widely used for the treatment of hypertension, and one angiotensin type 1 receptor blocker, telmisartan, specifically activates the peroxisome proliferator-activated receptor (PPAR)-gamma. We studied the impact of PPARgamma mutants on transcriptional control and interaction wit...

journal_title：Endocrinology

authors： Tagami T,Yamamoto H,Moriyama K,Sawai K,Usui T,Shimatsu A,Naruse M

更新日期：2009-02-01 00:00:00

abstract：:Cloning of GnRH receptors from several animal species has made it possible to investigate receptor function using site-directed mutagenesis. However, many mutant GnRH receptors exhibit decreased ligand binding, which makes analysis of their ligand binding characteristics technically difficult. To increase the affinity...

journal_title：Endocrinology

authors： Flanagan CA,Fromme BJ,Davidson JS,Millar RP

更新日期：1998-10-01 00:00:00

abstract：:The localization of calcitonin gene-related peptide (CGRP)-like immunoreactivity in the adrenal gland of the frog, Rana ridibunda, was examined by the indirect immunofluorescence technique. Using an antiserum directed against rat alpha-CGRP, the presence of a network of positive fibers was observed in the adrenal pare...

journal_title：Endocrinology

authors： Esneu M,Delarue C,Remy-Jouet I,Manzardo E,Fasolo A,Fournier A,Saint-Pierre S,Conlon JM,Vaudry H

更新日期：1994-07-01 00:00:00

abstract：:Little is known about the mechanisms of action of polypeptide hormones on chromatin structure and nuclear function. We have employed micrococcal nuclease to examine the effect of TSH on the accessibility of DNA in thyroid nuclei. Brief digestion of nuclear suspensions with 0.05-0.2 U/ml micrococcal nuclease at 26-28 C...

journal_title：Endocrinology

authors： Abe Y,Cooper E,Spaulding SW

更新日期：1982-06-01 00:00:00