Decomposition of alpha-hydroxyaryl ketones and characterization of some unusual products.


:Alpha-Hydroxyaryl ketones such as 2-hydroxypropiophenone and 1-(2,4-difluorophenyl)-2-hydroxy-1-propanone, the key intermediates in the preparation of antifungal agents, decompose into oxidized, rearranged, and condensed products. These products were isolated and characterized. The possible mechanisms for the formation of the products are discussed.


J Pharm Sci


Gala D,Puar MS,Das PR,Kugelman M,DiBenedetto DJ




Has Abstract


1992-12-01 00:00:00














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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Acree WE Jr,McHan DR,Rytting JH

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    pub_type: 杂志文章


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    更新日期:1996-08-01 00:00:00