[Efficacy, safety, and pharmaco-economical aspects of the therapy for dyslipidemia with brand-name and generic statins].

Abstract:

AIM:To compare clinical, cost-effect efficacies and safety of simvastatin Zokor and generic Vasilip in correction of dislipoproteinemia in patients with ischemic heart disease. MATERIAL AND METHODS:The original statin Zokor and generic statin Vasilip were given for 8 weeks in a dose 20 mg/day. RESULTS:Vasilip and Zokor demonstrated similar hypolipidemic efficacy and safety, but Vasilip administration was more cost-effective. CONCLUSION:Simvastatin Vasilip is recommended for wider use in clinical practice because it is clinically and cost effective.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Ol'binskaia LI,Danilogorskaia IuA

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

47-50

issue

12

eissn

0040-3660

issn

2309-5342

journal_volume

75

pub_type

临床试验,杂志文章
  • Hepatic involvement in sarcoidosis.

    abstract::Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Liver is frequently involved in the pathological process. Wide range of clinical manifestations can be seen: from asymptomatic lesion with normal liver function tests to cirrhosis with portal hypertension. Biopsy plays the key role in diagnosis of...

    journal_title:Terapevticheskii arkhiv

    pub_type: 社论

    doi:10.26442/00403660.2019.04.000179

    authors: Fomin VV,Brovko MY,Kalashnikov MV,Sholomova VI,Rozina TP,Akulkina LA,Pershina AE,Yanakayeva AS,Nekrasova TP

    更新日期:2019-05-15 00:00:00

  • [Effect of long-term epidural analgesia and nitroglycerin infusion on formation of necrosis zone and clinical course of myocardial infarction].

    abstract:AIM:To study effects of long-term morphine-clofelin epidural analgesia and infusion of nitroglycerin on formation of the necrosis focus and the clinical course of acute myocardial infarction (MI). MATERIAL AND METHODS:Ninety patients were examined within the first 12 hours of anterior macrofocal MI. Forty six patients...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Tumak VN,Dzizinskiĭ AA

    更新日期:2004-01-01 00:00:00

  • [Clinical, Virusological and Immunological characteristics of hospitalised HIV-infected patients].

    abstract:AIM:The primary objective of this study was to describe clinical, virusological and immunological characteristics of hospitalised HIV-infected patients, who had different stages of the disease. MATERIALS AND METHODS:This study was conducted at Moscow Infectious Diseases Hospital №2 in 2012-2015. We have clinically obs...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890114-23

    authors: Shakhgildyan VI,Yadrikhinskaya MS,Orlovsky AA,Yarovaya EB

    更新日期:2018-11-15 00:00:00

  • [The long-term prognosis of the course of different forms of ischemic heart disease and a scale for assessing its risk of death].

    abstract::The data obtained in a prospective study made it possible, using Markov's analysis, to assess different forms of coronary heart disease (CHD) of long duration and to elaborate an unsophisticated scale for estimating individual risk of death from that disease. The Markov's analysis demonstrated a high enough probabilit...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Plavinskaia SI,Shestov DB

    更新日期:1990-01-01 00:00:00

  • [The cough variant asthma].

    abstract::Cough variant asthma (CVA) was first described by W. Corrao. CVA was described as the isolated chronic cough as the only presenting symptom responsive to bronchodilator therapy.This phenotype of asthma is present with airway hyperresponsiveness, eosinophilic inflammation airways and bronchodilator responsive coughing ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/00403660.2020.03.000404

    authors: Uryasjev MO,Ponomareva IV,Bhar M,Glotov SI

    更新日期:2020-04-27 00:00:00

  • [Characteristics of lipid profile in blood plasma of patients with metabolic syndrome and manifest disorder of carbohydrate metabolism].

    abstract:AIM:To study specific features of lipid plasm profile in patients with metabolic syndrome (MS) and manifest disorder of carbohydrate metabolism (CM) as well as their relationships with clinical symptoms of MS. MATERIALS AND METHODS:Contents of lipids and apolipoproteins of plasm was measured on an empty stomach in 30 ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Medvedeva IV,Dorodneva EF,Pugacheva TA,Bel'chikova LN,Zhuravleva TD

    更新日期:2003-01-01 00:00:00

  • [Effects of long-acting calcium antagonists--amlodipine and diltiazem in patients with stable angina of effort: comparative randomized controlled trial].

    abstract:AIM:To compare effectiveness of two long-acting calcium antagonists--amlodipin and diltiazem--in patients with ischemic heart disease (IHD) and stable angina of effort (SAE). MATERIAL AND METHODS:31 IHD patients with SAE entered the double blind randomized trial. The patients received either amlodipin (5-10 mg once a ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Martsevich SIu,Sementsov DP,Kutishenko NP,Alimova EV

    更新日期:2001-01-01 00:00:00

  • [Chronic viral infection in patients with alcoholic liver involvement].

    abstract:AIM:Detection of viral hepatitides markers in patients with alcoholic damage to the liver. MATERIALS AND METHODS:Virological, immunological and histochemical tests were performed in 36 chronic alcoholics who had enlarged liver and/or abnormal hepatic characteristics. RESULTS:60% of the examinees carried chronic HBV, ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Nikitin IG,Storozhakov GI,Volynkina VM,Uskov IuI,Kisliakov VA,Shilo VIu

    更新日期:1998-01-01 00:00:00

  • [Efficiency of using cycloferon as part of combined therapy for chronic hepatitis C (a review of multicenter clinical trials)].

    abstract::The results of a study of the efficiency of treatment in patients with chronic hepatitis C conducted in a complex of multicenter clinical trials of the impact of various antiviral therapy regimens including the interferon genesis inductor cycloferon are reviewed. Four hundred and seventy-eight patients with hepatitis ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Sologub TV,Romantsev MG,Shul'diakov AA,Lin'kova IuN,Radchenko VG,Kovalenko AL

    更新日期:2010-01-01 00:00:00

  • [Anxiety disorders as psychological personality characteristics in patients with rheumatoid arthritis].

    abstract:AIM:To study types of anxious disorders (AD) in patients with rheumatoid arthritis (RA) and AD correlations with clinicolaboratory indices. MATERIAL AND METHODS:80 RA patients and 38 healthy subjects have undergone MMPI test. RESULTS:95% of the examinees were found to have AD which seem to form in active participatio...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ulanova EA,Grigor'ev IV,Novikova IA

    更新日期:2000-01-01 00:00:00

  • [Relationship between the intima-media complex thickness, the risk factors of cardiovascular diseases, and the level of C-reactive protein in gouty patients].

    abstract:AIM:To estimate a relationship between the intima-media thickness (TIM), cardiovascular risk (CVR) factors, and the level of C-reactive protein (CRP) in gouty patients. SUBJECTS AND METHODS:Eighty-nine patients at an interattack interval were examined. The patients' mean age was 46.0 +/- 11.4 years; the duration of th...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Il'ina AE,Varfolomeeva EI,Volkov AV,Mach ES,Aleksandrova EN,Novikov AA,Il'inykh EV,Barskova VG,Nasonov EL

    更新日期:2009-01-01 00:00:00

  • [Hepatitis B virus infection and glomerulonephritis].

    abstract::HBsAg was detected in the blood serum of patients with glomerulonephritis (GN) in 21.1% of cases. During examination of patients with other diseases of the kidneys HBsAg was detected in the blood serum much less frequently (8.3%). In patients with systemic autoimmune diseases it was found in 12.1%, in patients with py...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Filimonova RG,Tareeva IE,Mikhailov MI,Aprosina ZG,Nevraeva EG

    更新日期:1987-01-01 00:00:00

  • [Efficacy of one combined inhaled drug in the treatment of patients with bronchial asthma depending on the disease duration].

    abstract:AIM:To assess an effect of long-term administration of one combined inhaled drug containing glucocorticosteroids (GCS) and long-acting beta2-agonists (LABA) on patient compliance. MATERIAL AND METHODS:The trial included 47 patients (14 males and 33 females, mean age 48.8 +/- 13.2 years) with bronchial asthma (BA) of d...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ovcharenko SI,Akulova MN

    更新日期:2009-01-01 00:00:00

  • [Social stress as a risk factor for ischemic heart disease].

    abstract:AIM:To study dynamics of ischemic heart disease in exposure of the population of an industrial city to social-economic stress. MATERIAL AND METHODS:Official annual records of Saratov city Health Administration for 1989-1998. In public health evaluation, cardiovascular morbidity is the index rapidly reacting to social-...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Denisova TP,Shkoda AS,Malinova LI,Astaf'eva NG

    更新日期:2005-01-01 00:00:00

  • [Clinico-immunological characteristics of systemic lupus erythematosus with Raynaud and Sjögren's syndromes (report I)].

    abstract::Forty-one patients suffering from chronic systemic lupus erythematosus with Raynaud and Sjögren's syndromes and 18 patients with an acute and subacute disease course were examined. It was established that chronic SLE was marked by a high frequency of antibodies to ribonucleoprotein, an increase in the concentration of...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Nasonova VA,Poverennyĭ AM,Nasonov EL,Lekakh IV,Tachmuradova MD

    更新日期:1985-01-01 00:00:00

  • [Treatment for dyslipidemias in patients with arterial hypertension].

    abstract:AIM:To evaluate a combination of the effects of non-drug measures and rozuvastatin on the lipid spectrum and blood pressure (BP) in patients with treated arterial hypertension (AH) concurrent with dyslipidemia. MATERIALS AND METHODS:The multicenter open-labeled prospective program included 299 patients from 19 cities ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Chazova IE,Kukharchuk VV,Ratova LG,Kaminnaia VI

    更新日期:2007-01-01 00:00:00

  • [Acute Ph-negative lymphoblastic leukemias in adults: Risk factors in the use of the ALL-2009 protocol].

    abstract:AIM:to analyze well-known risk factors (RFs), such as age, immunophenotype, baseline leukocytosis, enhanced lactate dehydrogenase (LDH) activity, time to achieve complete remission, a risk group, and cytogenetic abnormalities) in patients with acute lymphoblastic leukemia (ALL) in the use of the ALL-2009 protocol. SUB...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh201688715-24

    authors: Parovichnikova EN,Sokolov AN,Troitskaya VV,Klyasova GA,Rusinov MA,Akhmerzaeva ZK,Kuzmina LA,Bondarenko SN,Baranova OY,Kaporskaya TS,Zotina EN,Zinina EE,Samoilova OS,Gavrilova LV,Kaplanov KD,Konstantinova TS,Lapin VA,Kra

    更新日期:2016-01-01 00:00:00

  • [The early form of arteriosclerosis obliterans of the arteries of the lower extremities].

    abstract::The analysis of literature and data obtained by the authors validate the necessity to recognize early atherosclerosis as a specific form of low limb vascular lesions. The latter are characterized by the presence of autoimmune inflammation in the vascular wall. The authors believe peripheral nonspecific aortic arteriti...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Koshkin VM,Sergeeva NA

    更新日期:1994-01-01 00:00:00

  • [The potentials of intestinoscopy and guided biopsy in the diagnosis of diseases of the small intestine].

    abstract:AIM:To ascertain the role of intestinoscopy in diagnosis of small intestinal diseases. MATERIALS AND METHODS:Intestinoscopy with multiple topographic biopsies was made with SIF-10 device (Olympus) in 92 patients. RESULTS:Of 60 patients with absorption disorders, the diagnosis of gluten enteropathy (GEP), Whipple's di...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Loginov AS,Parfenov AI,Vasil'ev IuV,Chikunova BZ,Parfenov DA

    更新日期:1999-01-01 00:00:00

  • [Impact of pharmacogenetic testing on the risk of bleedings and excessive hypocoagulation episodes in the use of warfarin: the first meta-analysis of Russian prospective studies].

    abstract:AIM:To perform a meta-analysis of Russian prospective studies comparing the pharmacogenetic versus conventional warfarin dosing procedures. MATERIALS AND METHODS:Publications were sought in the PubMed and eLibrary through September 30, 2013. Seven prospective studies comparing the pharmacogenetic method of warfarin do...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,meta分析

    doi:

    authors: Sychev DA,Ivashchenko DV,Rusin IV

    更新日期:2014-01-01 00:00:00

  • [Clinical significance of intravital morphological investigation of the liver].

    abstract:AIM:To demonstrate great importance of intravital morphological examination of the liver for differential diagnosis of chronic diffuse diseases (CDD) of the liver. MATERIAL AND METHODS:A complete clinical examination, needle or intraoperative biopsy of the liver were made in 1045 patients with chronic diseases of the ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Khomeriki SG,Iakhimchuk GN,Golovanova EV

    更新日期:2011-01-01 00:00:00

  • [A comparative analysis of normodipin and spirapril effects on intravascular activity of platelets in patients with metabolic syndrome].

    abstract:AIM:To study effects of two hypotensive drugs--normodipin and spirapril--on intravascular activity of platelets in patients with metabolic syndrome (MS). MATERIAL AND METHODS:Normodipin was given to 25 patients with MS for 3 months, spirapril--to 20 patients for 3 months. The effect was evaluated by changes in lipid p...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Medvedev IN

    更新日期:2007-01-01 00:00:00

  • [A case of myocardial infarction of anatomically right but functionally left ventricle in a middle-aged male patient with isolated corrected transposition of the major vessels].

    abstract::The article is devoted to a rare congenital heart disease--corrected transposition of the major vessels. A hemodynamic scheme of the disease, its probable prognosis, possible development of arrhythmia, impairment of conduction and cardiac failure are described. A case is reported of myocardial infarction of anatomical...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:2011-01-01 00:00:00

  • [Mortality and risk factors for non-communicable diseases in Russia: Specific features, trends, and prognosis].

    abstract::In the Russian Federation, the increase in all-cause and cardiovascular disease mortality began in the 1960s and lasted almost continuously until 2003. In our country, the characteristics of mortality are its substantially higher rates among men and a large regional variability, which is associated with economic, clim...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:10.17116/terarkh20178915-13

    authors: Boytsov SA,Deev AD,Shalnova SA

    更新日期:2017-01-01 00:00:00

  • [Efficacy of combined treatment of patients with severe obstructive sleep apnea and arterial hypertension of the second and third degree].

    abstract:AIM:To assess efficacy of two- and three-component antihypertensive treatment (AHT) in patients with severe sleep apnea and arterial hypertension (AH) of the second and third degree in combination with CPAP therapy (continuous positive air pressure) and without it. MATERIAL AND METHODS:A total of 58 patients aged 55.5...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Sukmarova ZN,Litvin AIu,Chazova IE,Rogoza AN

    更新日期:2011-01-01 00:00:00

  • [The value of bone mineral density assessment by dual-energy x-ray absorptiometry for prediction of cardiovascular mortality in patients treated with hemodialysis].

    abstract:AIM:Determine whether bone mineral density (BMD) assessed by dual-energy x-ray absorptiometry can be used as predictor of increased risk of death in hemodialysis patients. MATERIALS AND METHODS:A prospective study was performed of 516 patients with chronic kidney disease treated with hemodialysis (men 265, women 251, ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/00403660.2020.06.000277

    authors: Mazurenko SO,Nakatis YA,Enkin AA,Staroselsky KG,Vasiliev AN,Mazurenko OG,Soin PV,Ermolaeva LG,Ivanov IG

    更新日期:2020-07-09 00:00:00

  • Structure and significance of cytogenetic abnormalities in adult patients with Ph-negative acute lymphoblastic leukemia.

    abstract:AIM:To evaluate occurrence, variety, structural peculiarities and prognostic meaning of cytogenetic abnormalities in adult patients with Ph-negative acute lymphoblastic leukemia (ALL) receiving therapy according to ALL-2009 protocol. MATERIALS AND METHODS:The study included 115 adult patients with firstly diagnosed Ph...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.26442/terarkh201890730-37

    authors: Piskunova IS,Obukhova TN,Parovichnikova EN,Kulikov SM,Troitskaya VV,Gavrilina OA,Savchenko VG

    更新日期:2018-08-17 00:00:00

  • [Cardiac changes in hereditary spinocerebellar degenerations].

    abstract::Echocardiographic alterations were compared with the clinical picture in 32 patients with different forms of hereditary spinocerebellar degenerations (HSCD). Three groups of patients were examined. Group I included patients with Friedreich's ataxia (FA), group II consisted of patients with familial cerebellar degenera...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Illarioshkin SN,Borisenko VV,Ivanova-Smolenskaia IA

    更新日期:1990-01-01 00:00:00

  • [Clinical aspects of typhoid fever epidemic in migrants].

    abstract:AIM:To study clinical features of typhoid fever (TF) in migrants (subjects in military service in Tadjikistan). MATERIAL AND METHODS:In chronic water epidemic TF symptoms were studied in 547 young soldiers and officers serving in Tadjikistan with incomplete biological and/or professional adaptation. RESULTS:In most c...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Makhnev MV

    更新日期:2001-01-01 00:00:00

  • [Enzyme clearance in intermittent hemofiltration in patients with acute renal failure].

    abstract:AIM:To characterize elimination of some enzymes in intermittent hemofiltration (HF) in patients with acute renal failure (ARF). MATERIAL AND METHODS:22 patients with oliguric ARF have undergone 52 procedures of intermittent HF. Before the procedure and after it the activity of enzymes (AA, AP, ACE, LAP, GGT, GDG, AlAT...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Timokhov VS,Kazakov IV,Selezneva SN,Komissarova IV,Smirnova LM

    更新日期:2000-01-01 00:00:00