Diurnal fluctuation of leukocyte G6PD activity. A possible explanation for the normal neutrophil bactericidal activity and the low incidence of pyogenic infections in patients with severe G6PD deficiency in Israel.

abstract：:We banded the trachea of 4-wk-old male rats and studied lung growth, lung morphometry, and static pulmonary mechanics 4 wk later. We compared the experimental animals to sham-operated male littermates of the same age, 8-wk-old normal male littermates, and weight-matched rats of a younger age. Tracheal banded animals w...

journal_title：Pediatric research

authors： Kida K,Thurlbeck WM

更新日期：1981-03-01 00:00:00

abstract：:We evaluated the hypothesis that increased endogenous opioid activity mediates part or all of the left ventricular contractile and pump dysfunction previously demonstrated in HCl-induced metabolic acidemia. Eighteen Western newborn lambs were catheterized and instrumented; pacing wires were sutured to the right atrial...

journal_title：Pediatric research

authors： Fisher DJ,Dreyer WJ,Tate C,Michael L,Smith EO,Entman M

更新日期：1988-06-01 00:00:00

abstract：:To delineate the role of growth hormone (GH) in the development and function of the immune system, immunological parameters including quantitative immunoglobulins, T and B lymphocytes, phytohemagglutinin lymphoproliferative response and delayed hypersensitivity skin tests were studied in nine GH-deficient children pri...

journal_title：Pediatric research

authors： Abbassi V,Bellanti JA

更新日期：1985-03-01 00:00:00

abstract：:The renal effects of endothelin-1 were investigated in 16 anesthetized and mechanically ventilated newborn rabbits. Renal blood flow and glomerular filtration rate were determined by the clearance of para-aminohippuric acid and inulin, respectively. Each animal acted as its own control. In eight newborn rabbits, a bol...

journal_title：Pediatric research

authors： Semama DS,Thonney M,Guignard JP,Gouyon JB

更新日期：1993-08-01 00:00:00

abstract：:Three members of a Virginia family with a bleeding disorder were found to have a serum defect in thromboplastin generation similar to the previously reported "Car. factor" deficiency. Sera from three members of the original Car. family did not correct the defect of affected members of the Virginia family. Partial thro...

journal_title：Pediatric research

authors： Komp DM

更新日期：1975-04-01 00:00:00

abstract：:Neurogenesis persists throughout life in the rodent subventricular zone (SVZ) and increases in the adult after brain injury. In this study, postnatal day 7 (P7) rats underwent right carotid artery ligation followed by 8% O2 exposure for 90 min, a lesioning protocol that resulted in ipsilateral forebrain hypoxic-ischem...

journal_title：Pediatric research

authors： Ong J,Plane JM,Parent JM,Silverstein FS

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Maternal exposure to pesticides during pregnancy may cause oxidative hemolysis leading to neonatal hyperbilirubinemia. This investigation examined for associations between maternal use of pesticides or repellents during pregnancy and neonatal hyperbilirubinemia requiring phototherapy. METHODS:We used the da...

journal_title：Pediatric research

authors： Shibazaki T,Motoki N,Misawa Y,Ohira S,Inaba Y,Kanai M,Kurita H,Nakazawa Y,Tsukahara T,Nomiyama T,Japan Environment & Children’s Study (JECS) Group.

更新日期：2020-08-05 00:00:00

abstract：BACKGROUND:Aminoglycoside exposure is a common cause of acute kidney injury (AKI). Delay in the diagnosis of AKI using conventional biomarkers has been one of the important obstacles in applying early effective interventions. We tested the hypothesis that urinary metabolomics could identify novel early biomarkers for t...

journal_title：Pediatric research

authors： Hanna MH,Segar JL,Teesch LM,Kasper DC,Schaefer FS,Brophy PD

更新日期：2013-05-01 00:00:00

abstract：:The uterus is unique among smooth muscular organs in that, during pregnancy, it undergoes profound, largely reversible, changes orchestrated by the ovarian hormones. These changes facilitate uterine adaptation to the stretch induced by the growing fetus such that a state of myometrial contractile quiescence can be mai...

journal_title：Pediatric research

authors： Riemer RK,Heymann MA

更新日期：1998-11-01 00:00:00

abstract：:We tested whether reoxygenation with 100% O(2) for 5 min after experimental asphyxia in newborn piglets was as efficient as 100% O(2) for 20 min compared with room air. Forty-one anesthetized piglets, 1-3 d old, were randomized to cerebral hypoxemia-ischemia-hypercapnia (HIH) or control (n = 5). HIH was achieved by ve...

journal_title：Pediatric research

authors： Solas AB,Munkeby BH,Saugstad OD

更新日期：2004-07-01 00:00:00

abstract：:Progress has been made in the reduction of morbidity and mortality from neonatal sepsis. However, diagnosis continues to rely primarily on conventional microbiologic techniques, which can be inaccurate. The objective of this review is to provide the clinician with an overview of the current information available on di...

journal_title：Pediatric research

authors： Iroh Tam PY,Bendel CM

更新日期：2017-10-01 00:00:00

abstract：:This study aimed to characterize early neonatal microvascular function after preeclamptic pregnancy with respect to infant sex and in utero growth. Peripheral microvascular blood flow was examined prospectively from 6 to 72 h of age using laser Doppler flowmetry in a cohort of term infants of normotensive women and wo...

journal_title：Pediatric research

authors： Stark MJ,Clifton VL,Wright IM

更新日期：2009-03-01 00:00:00

abstract：:Inasmuch as taurine biosynthesis is decreased during early postnatal life, an efficient mechanism for taurine uptake by the liver must be present to maintain intracellular stores of this beta-amino acid. Therefore, basolateral liver plasma vesicles prepared from 14-day and adult rats were used to examine taurine trans...

journal_title：Pediatric research

authors： Bucuvalas JC,Goodrich AL,Suchy FJ

更新日期：1988-02-01 00:00:00

abstract：:Clinical studies have suggested that the early stages of bilirubin encephalopathy are reversible. These phenomena are investigated at the cellular level using the neuroblastoma cell line N-115 as a model system. To determine whether the cell line N-115 can recover from bilirubin toxicity, and whether the cellular func...

journal_title：Pediatric research

authors： Amit Y,Poznansky MJ,Schiff D

更新日期：1989-04-01 00:00:00

abstract：:The microbiome, of which the bacterial component alone (microbiota), is estimated to include 10 times more cells than human cells of the body, blooms immediately after birth and evolves in composition and complexity throughout childhood. The gut microbiome has a profound impact on gastrointestinal tract development, m...

journal_title：Pediatric research

authors： Unger S,Stintzi A,Shah P,Mack D,O'Connor DL

更新日期：2015-01-01 00:00:00

abstract：:The ventricular epicardial activation sequence (VEAS) in 15 anesthetized lambs (near term fetus to 3.5 months of age) was determined using 40 simultaneously recorded bipolar electrograms for each animal. Isochrone maps were drawn by hand using relative activation times determined from the maximum first derivative of m...

journal_title：Pediatric research

authors： Mathewson JW,Riemenschneider TA,Ruttenberg HD

更新日期：1977-01-01 00:00:00

abstract：:It is customary to estimate the uteroplacental function in singletons by defining appropriateness of birth weight by gestational age. Such a measure, however, is not available for the entire multiple pregnancy set. We evaluate a new index, total triplet birth weight, expressed as multiples of the median (MOM) birth we...

journal_title：Pediatric research

authors： Blickstein I,Salihu HM,Keith LG,Alexander GR

更新日期：2006-04-01 00:00:00

abstract：:The purpose of this investigation was to determine whether maximal oxygen consumption (VO2max) differed between two selected groups of black and white children and whether a difference existed to determine whether it was related to hematologic profiles, body composition, and/or physical activity/inactivity level. Fort...

journal_title：Pediatric research

authors： Andreacci JL,Robertson RJ,Dubé JJ,Aaron DJ,Balasekaran G,Arslanian SA

更新日期：2004-11-01 00:00:00

abstract：:Low IGF-I levels are found in patients with chronic liver disease, but it is not known whether these reductions in IGF-I are secondary to hepatic dysfunction or to malnutrition. To determine whether malnutrition associated with hepatic dysfunction causes the decrease in these levels, serum and liver IGF-I concentratio...

journal_title：Pediatric research

authors： Descos BP,Berry SA,Sharp HL,Gross CR,Weisdorf SA,Pescovitz OH

更新日期：1989-11-01 00:00:00

abstract：:The role of plasma glucose concentration in the regulation of endogenous glucose production in the human newborn was examined by infusing glucose at 2.6-4.6 mg/kg . min as a continuous infusion to eight normal term appropriate for gestational age infants, five preterm, and six small for gestational age infants. All in...

journal_title：Pediatric research

authors： Kalhan SC,Oliven A,King KC,Lucero C

更新日期：1986-01-01 00:00:00

abstract：:All enzymes of the urea cycle are demonstrable in circulating leukocytes. They show the same relative activities as those in liver except for argininosuccinate synthetase + lyase (combined) which seems to be disproportionately active. To see whether leukocytes reflect liver activity, blood from patients with three hep...

journal_title：Pediatric research

authors： Wolfe DM,Gatfield PD

更新日期：1975-06-01 00:00:00

abstract：:Newborn human infants, particularly those born prematurely, are susceptible to infection with a variety of microorganisms. We questioned whether limitations in the T cell repertoire contribute to the neonatal immunocompromised state. To describe developmental changes of the T cell repertoire, cDNA segments correspondi...

journal_title：Pediatric research

authors： Schelonka RL,Raaphorst FM,Infante D,Kraig E,Teale JM,Infante AJ

更新日期：1998-03-01 00:00:00

abstract：:Twenty-four samples of breast milk from nine mothers of infants suffering from breast milk jaundice were studied. Eight samples of milk from mothers of nonjaundiced infants, along with five formula milks enriched with polyunsaturated fatty acids, served as controls. Milks from mothers with jaundiced infants had no inh...

journal_title：Pediatric research

authors： Foliot A,Ploussard JP,Housset E,Christoforov

更新日期：1976-06-01 00:00:00

abstract：:Basal and pentagastrin-stimulated gastric acid secretion was measured in 26 healthy newborn infants on the 1st and 2nd days of life. Basal acid outputs (BAO) on day 1 (0.378 mEq/hr) and day 2 (0.388 mEq/hr) were similar and not significantly different from the maximal acid outputs (MAO) on day 1 (0.413 mEq/hr) and day...

journal_title：Pediatric research

authors： Euler AR,Byrne WJ,Meis PJ,Leake RD,Ament ME

更新日期：1979-01-01 00:00:00

abstract：:Treatment with phototherapy or with the lipase inhibitor orlistat decreases plasma unconjugated bilirubin (UCB) concentrations in hyperbilirubinemic Gunn rats. We investigated the mechanism(s) underlying the effects of orlistat, phototherapy, and combined treatment, using steady-state 3H-UCB kinetics. After three week...

journal_title：Pediatric research

authors： Hafkamp AM,Havinga R,Ostrow JD,Tiribelli C,Pascolo L,Sinaasappel M,Verkade HJ

更新日期：2006-04-01 00:00:00

abstract：:Indomethacin, because of its prostaglandin inhibition, may cause constriction of the ductus arteriosus and affect the pulmonary circulation. To study this possibility, we gave indomethacin daily by gavage to two groups of pregnant rats from the 17th day of pregnancy through delivery (group 1, 2 mg/kg/day; group 2, 4 m...

journal_title：Pediatric research

authors： Harker LC,Kirkpatrick SE,Friedman WF,Bloor CM

更新日期：1981-02-01 00:00:00

abstract：:The diagnosis of transient renal tubular acidosis was made in a 16 months old boy. Bicarbonate titration studies revealed that the acidification defect consisted of an association of proximal and distal tubular acidosis. The effect of experimentally induced potassium depletion revealed that hyperkalemia contributed to...

journal_title：Pediatric research

authors： Donckerwolcke RA,Valk C,van Wijngaarden-Penterman MJ,van Stekelenburg GJ

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Fetal hypoxia-ischemia (H-I) results in significant morbidity and mortality. Little is known about the timing of death in human stillbirths. The vulnerability of the fetus varies with age at the time of insult, but it is unknown what happens to the timing of fetal death in relation to a fetal insult. We aske...

journal_title：Pediatric research

authors： Derrick M,Englof I,Drobyshevsky A,Luo K,Yu L,Tan S

更新日期：2012-08-01 00:00:00

abstract：:We determined the inhibitory effects of concentrations of tin- and zinc protoporphyrin (1-100 microM) and mesoporphyrin (0.1-10 microM) on the in vitro heme oxygenase (HO) (E.C.1.14.99.3) activity in liver, spleen, and intestine 13,000 x g tissue supernatants from fasted adult male Wistar rats through measurement of c...

journal_title：Pediatric research

authors： Vreman HJ,Gillman MJ,Stevenson DK

更新日期：1989-10-01 00:00:00

abstract：:Serial plasma concentrations of immunoreactive 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), the stable hydration product of prostacyclin (PGI2), were measured with radioimmunoassay during the first month of life in 25 preterm infants with idiopathic respiratory distress syndrome (IRDS) and 38 preterm controls wi...

journal_title：Pediatric research

authors： Kääpä P,Koivisto M,Viinikka L,Ylikorkala O

更新日期：1982-10-01 00:00:00