An experimental and Monte Carlo investigation of the energy dependence of alanine/EPR dosimetry: I. Clinical x-ray beams.

abstract：:In this study, the quantitative accuracy of different attenuation correction strategies presently available for the High Resolution Research Tomograph (HRRT) was investigated. These attenuation correction methods differ in reconstruction and processing (segmentation) algorithms used for generating a micro-image from m...

journal_title：Physics in medicine and biology

authors： van Velden FH,Kloet RW,van Berckel BN,Molthoff CF,de Jong HW,Lammertsma AA,Boellaard R

更新日期：2008-01-07 00:00:00

abstract：:Many models exist for predicting toxicities based on dose-volume histograms (DVHs) or dose-surface histograms (DSHs). This approach has several drawbacks as firstly the reduction of the dose distribution to a histogram results in the loss of spatial information and secondly the bins of the histograms are highly correl...

journal_title：Physics in medicine and biology

authors： Buettner F,Gulliford SL,Webb S,Partridge M

更新日期：2011-04-07 00:00:00

abstract：:Monte Carlo methods have been applied to the study of the performance of antiscatter grids in radiography. Photon histories for imaging with a 20 cm thick water phantom irradiated with an 80 kV x-ray spectrum were generated by Monte Carlo simulation. The scattering and absorption of the photons transmitted from the ph...

journal_title：Physics in medicine and biology

authors： Chan HP,Doi K

更新日期：1982-06-01 00:00:00

abstract：:Two detectors for fast two-dimensional (2D) and quasi-three-dimensional (quasi-3D) verification of the dose delivered by radiotherapy beams have been developed at University and Istituto Nazionale di Fisica Nucleare (INFN) of Torino. The Magic Cube is a stack of strip-segmented ionization chambers interleaved with wat...

journal_title：Physics in medicine and biology

authors： Cirio R,Garelli E,Schulte R,Amerio S,Boriano A,Bourhaleb F,Coutrakon G,Donetti M,Giordanengo S,Koss P,Madon E,Marchetto F,Nastasi U,Peroni C,Santuari D,Sardo A,Scielzo G,Stasi M,Trevisiol E

更新日期：2004-08-21 00:00:00

abstract：:In robotic radiosurgery, it is necessary to compensate for systematic latencies arising from target tracking and mechanical constraints. This compensation is usually achieved by means of an algorithm which computes the future target position. In most scientific works on respiratory motion prediction, only one or two a...

journal_title：Physics in medicine and biology

authors： Ernst F,Dürichen R,Schlaefer A,Schweikard A

更新日期：2013-06-07 00:00:00

abstract：:Range verification in proton therapy is a critical quality assurance task. We studied the feasibility of online range verification based on proton-induced acoustic signals, using a bidirectional long-short-term-memory recurrent neural network and various signal processing techniques. Dose distribution of 1D pencil pro...

journal_title：Physics in medicine and biology

authors： Yao S,Hu Z,Zhang X,Lou E,Liang Z,Wang Y,Peng H

更新日期：2020-11-05 00:00:00

abstract：:Mean glandular dose (MGD) is the figure of merit to assess breast dose after a mammographic acquisition. The use of normalized MGD obtained from Monte Carlo computations with measured incident air kerma determines the MGD delivered to patients. The Geant4 Application for Tomographic Emission (GATE) toolkit is a modern...

journal_title：Physics in medicine and biology

authors： Myronakis ME,Zvelebil M,Darambara DG

更新日期：2013-04-07 00:00:00

abstract：:This study investigated the temperature elevation in the eye of anatomically based human head models for plane-wave exposures. The finite-difference time-domain method is used for analyzing electromagnetic absorption and temperature elevation. The eyes in the anatomic models have average dimensions and weight. Computa...

journal_title：Physics in medicine and biology

authors： Hirata A,Watanabe S,Fujiwara O,Kojima M,Sasaki K,Shiozawa T

更新日期：2007-11-07 00:00:00

abstract：:This paper presents a method to obtain the pencil-beam kernels that characterize a megavoltage photon beam generated in a flattening filter free (FFF) linear accelerator (linac) by deconvolution from experimental measurements at different depths. The formalism is applied to perform independent dose calculations in mod...

journal_title：Physics in medicine and biology

authors： Azcona JD,Barbés B,Wang L,Burguete J

更新日期：2016-01-07 00:00:00

abstract：:Measurement of the dielectric properties of ocular tissues up to 110 GHz was performed by the coaxial probe method. A coaxial sensor was fabricated to allow the measurement of small amounts of biological tissues. Four-standard calibration was applied in the dielectric property measurement to obtain more accurate data ...

journal_title：Physics in medicine and biology

authors： Sasaki K,Isimura Y,Fujii K,Wake K,Watanabe S,Kojima M,Suga R,Hashimoto O

更新日期：2015-08-21 00:00:00

abstract：:We show how the spectral imaging framework should be modified to account for a high fraction of Compton interactions in low Z detector materials such as silicon. Using this framework, where deposited energies differ from actual photon energies, we compare the performance of a silicon strip detector, including the infl...

journal_title：Physics in medicine and biology

authors： Bornefalk H,Danielsson M

更新日期：2010-04-07 00:00:00

abstract：:Burst-tone focused ultrasound exposure in the presence of microbubbles has been demonstrated to be effective at inducing temporal and local opening of the blood-brain barrier (BBB), which promises significant clinical potential to deliver therapeutic molecules into the central nervous system (CNS). Traditional contras...

journal_title：Physics in medicine and biology

authors： Tsai CH,Zhang JW,Liao YY,Liu HL

更新日期：2016-04-07 00:00:00

abstract：:This work applies a previously developed analytical algorithm to the reconstruction problem in a rotating multi-segment slant-hole (RMSSH) SPECT system. The RMSSH collimator has greater detection efficiency than the parallel-hole collimator with comparable spatial resolution at the expense of limited common volume-of-...

journal_title：Physics in medicine and biology

authors： Huang Q,Xu J,Tsui BM,Gullberg GT

更新日期：2009-07-07 00:00:00

abstract：:Noise equivalent count rate (NECR) and image noise are two different but related metrics that have been used to predict and assess image quality, respectively. The aim of this study is to investigate, using patient studies, the relationships between injected dose (ID), body mass index (BMI) and scanner type on NECR an...

journal_title：Physics in medicine and biology

authors： Chang T,Chang G,Kohlmyer S,Clark JW,Rohren E,Mawlawi OR

更新日期：2011-08-21 00:00:00

abstract：:In this note a technique is described for direct aperture optimization of components deliverable by a variable aperture collimator (VAC) for intensity-modulated radiation therapy. The first key result found was that, provided a large number of VAC components were selected for optimization, the resulting fluence profil...

journal_title：Physics in medicine and biology

authors： Webb S

更新日期：2004-03-07 00:00:00

abstract：:Dose calculation for radiotherapy with protons and heavier ions deals with a large volume of path integrals involving a scattering power of body tissue. This work provides a simple model for such demanding applications. There is an approximate linearity between RMS end-point displacement and range of incident particle...

journal_title：Physics in medicine and biology

authors： Kanematsu N

更新日期：2009-03-07 00:00:00

abstract：:The analysis of (x-ray) mammograms remains qualitative, relying on the judgement of clinicians. We present a novel method to compute a quantitative, normalized measure of tissue radiodensity traversed by the primary beam incident on each pixel of a mammogram, a measure we term the standard attenuation rate (SAR). SAR ...

journal_title：Physics in medicine and biology

authors： Tromans CE,Cocker MR,Brady SM

更新日期：2012-10-21 00:00:00

abstract：:The probability of a photon (x-ray, gamma-ray, bremsstrahlung, etc) of a given energy E undergoing absorption or scattering when traversing a layer of material Z can be expressed quantitatively in terms of a linear attenuation coefficient mu (cm(-1)). Since mu is dependent on the material's density, rho (g cm(-3)), wh...

journal_title：Physics in medicine and biology

authors： Hubbell JH

更新日期：1999-01-01 00:00:00

abstract：:A phantom study was performed in full-field digital mammography to investigate the opportunity and the magnitude of a possible dose reduction that would leave the image quality above the accepted thresholds associated with some classical phantoms. This preliminary work is intended to lay the groundwork for a future cl...

journal_title：Physics in medicine and biology

authors： Gennaro G,Katz L,Souchay H,Alberelli C,di Maggio C

更新日期：2005-04-21 00:00:00

abstract：:Temperature distributions resulting from hyperthermia treatments on isolated perfused bovine tongues were compared with simulations by a treatment planning system. The aim was to test whether the discrete vessel model used for the treatment planning is able to predict correct generic temperature distributions. Tongues...

journal_title：Physics in medicine and biology

authors： Raaymakers BW,Crezee J,Lagendijk JJ

更新日期：1998-05-01 00:00:00

abstract：:Positron emission tomography (PET) iterative 3D reconstruction is a very computational demanding task. One of the main issues of the iterative reconstruction concerns the management of the system response matrix (SRM). The SRM models the relationship between the projection and the voxel space and its memory footprint ...

journal_title：Physics in medicine and biology

authors： Camarlinghi N,Sportelli G,Guerra AD,Belcari N

更新日期：2018-09-28 00:00:00

abstract：:A reader study was conducted to tune the parameters of an observer model used to predict the detectability index (dʹ ) of test objects as a task-based quality control (QC) metric for digital mammography. A simple test phantom was imaged to measure the model parameters, namely, noise power spectrum,modulation transfer ...

journal_title：Physics in medicine and biology

authors： Bloomquist AK,Mainprize JG,Mawdsley GE,Yaffe MJ

更新日期：2014-11-07 00:00:00

abstract：:In brachytherapy, plans are routinely calculated using the AAPM TG43 formalism which considers the patient as a simple water object. An accurate modeling of the physical processes considering patient heterogeneity using Monte Carlo simulation (MCS) methods is currently too time-consuming and computationally demanding ...

journal_title：Physics in medicine and biology

authors： Lemaréchal Y,Bert J,Falconnet C,Després P,Valeri A,Schick U,Pradier O,Garcia MP,Boussion N,Visvikis D

更新日期：2015-07-07 00:00:00

abstract：:This is a proof of principle study on an algorithm for optimizing external beam radiotherapy in terms of both photon beamlet energy and fluence. This simultaneous beamlet energy and fluence optimization is denoted modulated photon radiotherapy (XMRT). XMRT is compared with single-energy intensity modulated radiotherap...

journal_title：Physics in medicine and biology

authors： McGeachy P,Villarreal-Barajas JE,Zinchenko Y,Khan R

更新日期：2016-02-21 00:00:00

abstract：:A parametric model for the x-ray linear attenuation coefficient is used to describe the compositional dependence of Hounsfield numbers measured by medical CT scanners. Measurements with materials of known density and composition, that span and evenly sample the compositional range of tissues, are written as linear sim...

journal_title：Physics in medicine and biology

authors： Midgley SM

更新日期：2014-12-07 00:00:00

abstract：:During image-guided cancer radiation treatment, three-dimensional (3D) tumor volumetric information is important for treatment success. However, it is typically not feasible to image a patient's 3D tumor continuously in real time during treatment due to concern over excessive patient radiation dose. We present a new i...

journal_title：Physics in medicine and biology

authors： Mao S,Wu H,Sandison G,Fang S

更新日期：2017-02-21 00:00:00

abstract：:Dynamic positron emission tomography (PET) imaging can provide information about metabolic changes over time, used for kinetic analysis and auxiliary diagnosis. Existing deep learning-based reconstruction methods have too many trainable parameters and poor generalization, and require mass data to train the neural netw...

journal_title：Physics in medicine and biology

authors： Wang B,Liu H

更新日期：2020-10-13 00:00:00

abstract：:The purpose of this paper for four-dimensional (4D) computed tomography (CT) is threefold. (1) A new spatiotemporal model is presented from the matrix perspective with the row dimension in space and the column dimension in time, namely the robust PCA (principal component analysis)-based 4D CT model. That is, instead o...

journal_title：Physics in medicine and biology

authors： Gao H,Cai JF,Shen Z,Zhao H

更新日期：2011-06-07 00:00:00

abstract：:In external beam radiation therapy, radioactive beams offer the best clinical solution to simultaneously treat and in vivo monitor the dose delivery and tumor response using PET or PET-CT imaging. However, difficulties mainly linked to the low production efficiency have so far limited their use. This study is devoted ...

journal_title：Physics in medicine and biology

authors： Lazzeroni M,Brahme A

更新日期：2011-03-21 00:00:00

abstract：:Picking geometrically relevant atlases from the whole training set is crucial to multi-atlas based image segmentation, especially with extensive data of heterogeneous quality in the Big Data era. Unfortunately, there is very limited understanding of how currently used image similarity criteria reveal geometric relevan...

journal_title：Physics in medicine and biology

authors： Zhao T,Ruan D

更新日期：2016-06-07 00:00:00