Living donor transplant: wider selection criteria.

Abstract:

:The availability of cadaveric donor organs is insufficient for actual needs. The organ demand increases by 20% per year. Living donor transplant (LDT) may be a valid therapeutical alternative provided one uses proper criteria. LDT provides many advantages, like improved patient and organ survival, short waiting time, and the possibility to carefully plan the procedure. Potential risks include perioperative mortality and renal dysfunction in the kidney donor. At present, kidney LDTs in Italy represent 8% of the total, with an organ survival rate of 97% after 1 year (vs 93% for cadaveric transplants) and donors mortality rate of almost null. Most LDTs are performed from kinsmen. Presently, law no. 458, 26 June 1967, is in force in Italy for kidney LDT and law no. 453, 16 December 1999, for liver LDT. The foundations of LDT are, of course, the recipient's condition, the donor's motivation, and the altruism of the donation. It is desirable that in the future an increasing number of LDT be performed, supported by a careful, widespread health education regarding organ donation from living subjects and by the possibility to obtain insurance for the donor, which has been considered but never provided by actual laws.

journal_name

Transplant Proc

authors

Splendiani G,Cipriani S,Valeri M,Torlone N,Vega A,Tullio T,Condò S,Dominijanni S,Casciani CU

doi

10.1016/j.transproceed.2004.02.003

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

470-2

issue

3

eissn

0041-1345

issn

1873-2623

pii

S0041134504001472

journal_volume

36

pub_type

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