Abstract：
BACKGROUND:Cold air stimulates upper airway cold receptors causing a reflex depressive effect on respiratory activity. Menthol, in low concentrations can also stimulate these same cold receptors causing a depressive effect on respiratory activity. Menthol cigarettes when smoked, deliver enough menthol to stimulate cold receptors resulting in the smoker experiencing a "cool sensation." The "cool sensation" experienced by the menthol smoker can result in a reflex-depressive effect on respiratory activity. METHOD:Literature searches were done for the NLM databases (e.g., MEDLINE from 1966, TOXLINE, OLDMEDLINE (1985-1965), CANCERLIT, plus tobacco industry documents and hardcopy indices. The evidence was evaluated with application to mentholated cigarette smoking. RESULTS AND DISCUSSION:A logical progression is presented that develops the framework to prove that menthol found in mentholated cigarettes may cause respiratory depression resulting in greater exposure to the toxic substances found in tobacco smoke. CONCLUSION:As a result of breath holding that results from the stimulation of cold receptors there is a greater opportunity for exposure and transfer of the contents of the lungs to the pulmonary circulation. For the menthol smoker this results in a greater exposure to nicotine and the particulate matter (tar) of the smoked cigarette. This exposure can result in increased nicotine dependence and greater chance of tobacco-attributable disease.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Garten S,Falkner RVdoi
10.1016/j.ypmed.2004.01.019subject
Has Abstractpub_date
2004-06-01 00:00:00pages
793-8issue
6eissn
0091-7435issn
1096-0260pii
S0091743504000398journal_volume
38pub_type
杂志文章,评审abstract：:For good reason, there is increasing interest in assessing the clinical efficacy of dietary supplements, naturally occurring compounds, and nutraceuticals intended for improving health and reducing disease. This is also a pressing interest in mitigating the effects of age-dependent chronic diseases. This opportunity a...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ypmed.2012.04.001
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:The objective of the study is to evaluate cross-sectional and longitudinal changes in children's commuting to school in a representative sample of a Brazilian city. METHODS:Two school-based studies were carried out in 2002 (n=2936; 7-10 years old) and 2007 (n=1232; 7-15 years old) in Florianopolis, Brazil. C...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2012.06.023
更新日期：2012-09-01 00:00:00
abstract：:The Patient Protection and Affordable Care Act (ACA) has increased insurance coverage among underserved individuals, but the effect of ACA on cancer diagnosis is currently debated, particularly in Medicaid non-expansion states. Therefore, we aimed to assess the effect of ACA implementation on stage at diagnosis among ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2019.06.006
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Although extraordinary advances have been made in the management of advanced coronary artery disease, little progress has been made in its prevention. Traditional screening methods utilizing risk factor profiles and exercise treadmill tests have failed to identify populations who will subsequently have coron...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1006/pmed.2000.0813
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Previous studies have reported high interest in genetic testing for risk for colon or breast-ovarian cancer. These studies, however, have used samples which might be atypical with regard to level of interest evident among the general U.S. population. METHODS:As part of an annual statewide telephone health s...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1996.0086
更新日期：1996-09-01 00:00:00
abstract：:We aimed to assess the effectiveness of 'Paesaggi di Prevenzione', a school-based prevention program delivered by trained teachers and designed to tackle smoking, alcohol misuse, dietary risks, and physical inactivity in adolescence. We evaluated the program between 2010 and 2013 with a two-arm, parallel-group, multic...
journal_title：Preventive medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ypmed.2019.04.001
更新日期：2019-07-01 00:00:00
abstract：:The purpose of this study was to assess accuracy in predicting adolescent smoking status using attitude, knowledge, behavioral, and sociodemographic variables. A cohort of 4,641 schoolchildren was tested in 1975 (grades 4-6), in 1978 (grades 6-8), and, finally, in 1983 (grades 10-12). From 1978 to 1983, eight variable...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(87)90042-9
更新日期：1987-05-01 00:00:00
abstract：:Growing evidence reveals various neighborhood conditions are associated with the risk of developing type 2 diabetes. It is unknown, however, whether the effectiveness of diabetes prevention interventions is also influenced by neighborhood characteristics. The purpose of the current study is to examine the impact of ne...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2018.03.009
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:To investigate the psychometric properties of a new measure of barriers youth encounter while walking to specific destinations and to validate the measure with self-reported walking to these destinations. METHODS:In 2005 in Boston, Cincinnati and San Diego, parents of youth (n=289, aged 5-18) and adolescents...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2007.12.006
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND:This study examined the potential for tobacco use and other health risk behavior interventions in the context of an urban sexually transmitted diseases (STD) clinic. METHODS:A cross-sectional survey of two populations. Adolescents seen at an STD clinic or at the teen clinic of a community health center comp...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1998.0359
更新日期：1998-11-01 00:00:00
abstract：:Participation in recommended levels of physical activity promotes a healthy body weight and reduced chronic disease risk. To inform investment in prevention initiatives, we simulate the national implementation, impact on physical activity and childhood obesity and associated cost-effectiveness (versus the status quo) ...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ypmed.2016.10.017
更新日期：2017-02-01 00:00:00
abstract：:Tamoxifen citrate, the most extensively evaluated antiestrogen, acts primarily as a cytostatic agent by binding to the estrogen receptor. In rodent mammary model systems, when tamoxifen is given continuously after exposure to a carcinogen, the majority of expected tumors do not develop. In humans, adjuvant tamoxifen t...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1016/0091-7435(89)90037-6
更新日期：1989-09-01 00:00:00
abstract：BACKGROUND:Nutrition education tailored to individual characteristics of people might be more effective than general nutrition education. Nowadays, the use of computers makes individualized feedback available for larger groups. METHODS:The impact of tailored nutrition information on changes in fat, vegetable, and frui...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/pmed.1996.0052
更新日期：1996-05-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to identify patterns of mammogram and Papanicolaou (Pap) screenings among Mexican American women ages 67 and over. METHODS:Data on 1,403 Mexican American women from the Hispanic Established Population for the Epidemiological Study of the Elderly, a cohort study of community-dwellin...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.2001.0880
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:The benefits of childhood physical activity include fitness, weight control, and exercise habits that may carry over into adulthood. School physical education is the primary program responsible for training the nation's youth to be physically active and national objectives call for students to be engaged in ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1994.1059
更新日期：1994-07-01 00:00:00
abstract：BACKGROUND:Smokers who identified smoking cessation as the primary activity they could undertake to improve their health were compared with smokers who did not identify smoking cessation. Examined factors included personal characteristics, health status, smoking attitudes and behaviors, and social factors. METHODS:Sub...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1995.1063
更新日期：1995-07-01 00:00:00
abstract：:While several cross-sectional studies have shown that self-efficacy, self-esteem and optimism are associated with the use of routine health check-ups, little is known about this relationship based on longitudinal studies. Consequently, the purpose of this study was to examine whether these factors are associated with ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2017.08.030
更新日期：2017-12-01 00:00:00
abstract：:This study aimed to assess the impact of coronavirus disease (COVID-19) prevalence in the United States in the week leading to the relaxation of the stay-at-home orders (SAH) on future prevalence across states that implemented different SAH policies. We used data on the number of confirmed COVID-19 cases as of August ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2021.106435
更新日期：2021-01-22 00:00:00
abstract：METHODS:Serum lipoprotein profiles in 4,231 individuals, ages 5-26 years, were studied cross-sectionally in a biracial community to describe the race- and gender-specific changes from adolescence into young adulthood. RESULTS:White children and adolescents of both genders showed significantly higher covariates--adjust...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(91)90063-a
更新日期：1991-11-01 00:00:00
abstract：:The purpose of this research is to investigate peer-to-peer sexual violence victimization and perpetration among male and female adolescents in a large, racially and economically diverse, community-based sample. Using cross-sectional data over a four-year period (2009-2013) from a regional sample of middle school and ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2018.08.032
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:5 a Day for Better Health is a simple message encouraging people to eat more fruits and vegetables. The Seattle 5 a Day worksite investigators designed and evaluated an intervention, organized on stages of behavioral change, to increase worksitewide fruit and vegetable consumption. METHODS:We recruited 28 w...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/pmed.2000.0806
更新日期：2001-03-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(87)90065-x
更新日期：1987-07-01 00:00:00
abstract：:The dramatic increase in youth use of electronic nicotine delivery systems (ENDS; e.g., e-cigarettes) in the United States has focused regulatory efforts to address this concern while still encouraging smokers to switch completely to lower risk products or quit all tobacco product use. Increases in the minimum age for...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2020.106145
更新日期：2020-11-01 00:00:00
abstract：:Long-term prescription opioid use is associated both with new-onset and recurrence of depression. Whether chronic opioid use interferes with depression management has not been reported, therefore we determined whether patients' longer duration of opioid use and higher opioid dose are associated with new-onset treatmen...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2016.08.003
更新日期：2016-10-01 00:00:00
abstract：:The analysis of cancer prevention trials necessitates specialized procedures. Differences in the analysis plan between cancer prevention and therapy trials are emphasized. Discussion is focused upon (a) how trial conduct influences the analysis, (b) how noncompliance affects the analysis and the considerations this ra...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(91)90011-r
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Adequate care for patients with cardiovascular risks requires an adequate practice organization. Educational outreach visits are a promising approach to modifying professional behavior. We aimed to assess whether the quality of cardiovascular preventive care in general practice can be improved through a comp...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1006/pmed.2002.1095
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:This study seeks to measure exposure to secondhand smoke and to evaluate potential differences in knowledge, attitudes, and tolerance of secondhand smoke among subgroups of Asian Americans in the Delaware Valley region of Pennsylvania and New Jersey. METHODS:A cross-sectional study was conducted among 1374 ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.11.022
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVE:We estimated uptake of seasonal and 2009 influenza A(H1N1) vaccine among U.S. adults and assessed their perceptions of the seriousness of both types of influenza and corresponding attitudes toward vaccination during the 2009-2010 influenza season. We further documented how vaccine uptake and attitudes varied ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2010.05.008
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:The epidemiologic observation that physical activity reduces the risk for hypertension has only been made for white men who self-reported hypertension. This study examined physical activity and clinically determined incident hypertension in black and white men and women of the Atherosclerosis Risk in Communi...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1998.0431
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:In a population-based sample of smokers in early motivational stages, we found a high acceptance of smoking cessation groups. METHODS:Inter99 is a randomized population-based intervention study, in Copenhagen, Denmark. Smokers in all motivational stages were included. All participants underwent a lifestyle ...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ypmed.2004.06.011
更新日期：2005-03-01 00:00:00
