Contribution of functional neuroimaging to understanding neuropsychiatric side effects of interferon in hepatitis C.

Abstract:

:Patients with hepatitis C who are treated with interferon may develop neuropsychiatric symptoms, including fatigue and depression. The authors discuss the potential use of functional neuroimaging in the identification and treatment of these patients. The authors provide an overview of functional neuroimaging studies of fatigue and depressive symptoms in various medical and psychiatric conditions and suggest future directions for research that may increase understanding of the specific neural substrates of neuropsychiatric side effects associated with hepatitis C and interferon treatment. This knowledge may help consultation-liaison psychiatrists identify patients at high risk for developing side effects related to hepatitis C and interferon, which would allow for implementation of validated strategies for prophylactic treatment of these patients.

journal_name

Psychosomatics

journal_title

Psychosomatics

authors

Matthews SC,Paulus MP,Dimsdale JE

doi

10.1176/appi.psy.45.4.281

subject

Has Abstract

pub_date

2004-07-01 00:00:00

pages

281-6

issue

4

eissn

0033-3182

issn

1545-7206

pii

S0033-3182(04)70167-X

journal_volume

45

pub_type

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