Abstract:
:Depression is the major psychiatric complication of Parkinson's disease, and it occurs in approximately one-third of all cases. Diagnosis of depression is complicated by the overlap of depressive and parkinsonian symptoms. Its etiology is not fully understood but involves changes in dopamine and serotonin. Depression has significant clinical impact; depressed patients are more disabled (less independent). The depressive symptoms respond to treatment with antidepressants and electroconvulsive therapy.
journal_name
Psychosomaticsjournal_title
Psychosomaticsauthors
Guze BH,Barrio JCdoi
10.1016/S0033-3182(91)72039-2subject
Has Abstractpub_date
1991-10-01 00:00:00pages
390-5issue
4eissn
0033-3182issn
1545-7206pii
S0033-3182(91)72039-2journal_volume
32pub_type
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