Abstract:
BACKGROUND:Marfan syndrome (MFS) is a rare, heritable disorder that affects connective tissue. Men and women are equally affected. Clinical manifestations involve multiple sites, especially bones and ligaments and heart and blood vessels. OBJECTIVE:Authors sought to investigate quality of life (QoL) in MFS patients, assessing positive and negative sociodemographic factors and self-perceived well-being and functional status. METHOD:Thirty-six patients affected by MFS were interviewed and were administered the SF-36 psychometric questionnaire. RESULTS:Subjects affected by MFS reported an impaired quality of life in the psychological domain but not in the physical domain, as compared with a healthy population. Being male and older was significantly associated with a poorer perceived mental QoL. CONCLUSION:The authors found that MFS negatively influences QoL, increases psychological distress, and may be a possible risk for some psychiatric disorders.
journal_name
Psychosomaticsjournal_title
Psychosomaticsauthors
Fusar-Poli P,Klersy C,Stramesi F,Callegari A,Arbustini E,Politi Pdoi
10.1176/appi.psy.49.3.243subject
Has Abstractpub_date
2008-05-01 00:00:00pages
243-8issue
3eissn
0033-3182issn
1545-7206pii
49/3/243journal_volume
49pub_type
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