Abstract:
:A study was conducted on a group of chronically hospitalized, brain-damaged male patients to assess the effectiveness of treatment with pindolol on behavioral problems. The study was conducted in two parts. The first was a double-blind, placebo-controlled analysis of the effect of pindolol on assaultive behavior, both verbal and physical. The second part was open and sought to determine whether pindolol would diminish such behaviors as resistance to care, sexual preoccupation, or provocation of others, which were sufficient to preclude placement at a lower level of care. These target behaviors and nursing interventions were monitored and clinical global assessments of improvement in behavior and of suitability for lower levels of care were developed. Eight of 13 patients were considered improved. Those with significant premorbid personality disorders showed little benefit. Pindolol appears to ameliorate some management problems and, by inference, improve the quality of life in many patients with behavioral pathology due to organic brain disease.
journal_name
Psychosomaticsjournal_title
Psychosomaticsauthors
Greendyke RM,Berkner JP,Webster JC,Gulya Adoi
10.1016/S0033-3182(89)72297-0subject
Has Abstractpub_date
1989-04-01 00:00:00pages
161-5issue
2eissn
0033-3182issn
1545-7206pii
S0033-3182(89)72297-0journal_volume
30pub_type
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