Endogenous and exogenous glucocorticoids decrease plasma ghrelin in humans.

abstract：OBJECTIVES:HDLs have many diverse functions. The goal of this study was to determine the association of HDL cholesterol (HDL-C) and apolipoprotein A-I (apoA-I) with the development of type 2 diabetes (T2D). In particular, this study determined the association between the ratio of HDL-C to apoA-I (HA) and incident T2D. ...

journal_title：European journal of endocrinology

authors： Hwang YC,Ahn HY,Park SW,Park CY

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To characterise distinctive clinical features of giant prolactinomas in women. DESIGN:A multicentre, retrospective case series and literature review. METHODS:We collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 μg/l and identified 19 similar case...

journal_title：European journal of endocrinology

authors： Delgrange E,Raverot G,Bex M,Burman P,Decoudier B,Devuyst F,Feldt-Rasmussen U,Andersen M,Maiter D

更新日期：2013-11-22 00:00:00

abstract：:Puberty is the period during which we attain adult secondary sexual characteristics and reproductive capability. Its onset depends upon reactivation of pulsative GNRH, secretion from its relative quiescence during childhood, on the background of intact potential for pituitary-gonadal function. This review is intended:...

journal_title：European journal of endocrinology

authors： Dunkel L,Quinton R

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Pretibial myxedema (PM) is a manifestation of Graves' disease (GD). Currently, its diagnosis depends on physicians' observation and biopsy. No satisfactory, objective, and non-invasive tool is available to record and investigate lesions. Digital infrared thermal imaging (DITI) detects surface temperature, and...

journal_title：European journal of endocrinology

authors： Shih SR,Lin MS,Li HY,Yang HY,Hsiao YL,Chang MT,Chen CM,Chang TC

更新日期：2011-04-01 00:00:00

abstract：:The study was undertaken to investigate the interaction between the release of endothelin-1 (ET-1) and prolactin (PRL) from human decidualized endometrial cells, and the effects of transforming growth factor (TGF)-beta 1 on the release of ET-1 and PRL from human decidual cells in the early stage of pregnancy. Stromal ...

journal_title：European journal of endocrinology

authors： Kubota T,Taguchi M,Kobayashi K,Masuda M,Aso T

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:In type I diabetes mellitus, early markers of beta cell damage are needed in order to detect the infraclinical development of the disease. The reg protein may be a good candidate, as the reg gene has been proposed to play a role in the pancreatic beta cell destruction/regeneration process during diabetogenesi...

journal_title：European journal of endocrinology

authors： Christofilis MA,Carrere J,Atlan-Gepner C,Zevaco-Mattei C,Thivolet C,Baeza N,Figarella C,Vialettes B

更新日期：1999-10-01 00:00:00

abstract：:For patients with neuroendocrine tumours (NETs) of the gastrointestinal tract and pancreas (GEP) (GEP-NETs), excellent care should ideally be provided by a multidisciplinary team of skilled health care professionals. In these patients, a combination of nuclear medicine imaging and conventional radiological imaging tec...

journal_title：European journal of endocrinology

authors： de Herder WW

更新日期：2014-04-10 00:00:00

abstract：OBJECTIVE:Although fibroblast growth factor 23 (FGF23) has been implicated in the pathogenesis of cardiovascular disease, the relationship between FGF23 and cardiovascular disease has not been well characterized in the general population. The aim of this study was to determine whether serum FGF23 is independently assoc...

journal_title：European journal of endocrinology

authors： Dalal M,Sun K,Cappola AR,Ferrucci L,Crasto C,Fried LP,Semba RD

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies have shown that more than 50% of patients with congestive heart failure (CHF) have decreased bone mineral density (BMD). There is limited knowledge about the longitudinal changes of BMD and how to treat bone loss in patients with CHF. METHODS:The present study was a prospective, long...

journal_title：European journal of endocrinology

authors： Frost RJ,Sonne C,Wehr U,Stempfle HU

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Transient neonatal hyperthyrotropinemia (TNH) is defined as a neonatal abnormality of thyroid function, which reverts to normal at re-examination after 2 weeks of life. The thyroid function of these infants has not been sufficiently studied in terms of the risk of developing persistent hyperthyrotropinemia (P...

journal_title：European journal of endocrinology

authors： Cuestas E,Gaido MI,Capra RH

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Ghrelin is an orexigenic 28-amino acid peptide produced by the stomach. Circulating ghrelin levels rise shortly before and fall shortly after every meal. Peptide YY (PYY), an anorexigenic 36-amino acid peptide, is secreted primarily from the intestinal mucosa of the ileum and large intestine. Plasma...

journal_title：European journal of endocrinology

authors： Bizzarri C,Rigamonti AE,Luce A,Cappa M,Cella SG,Berini J,Sartorio A,Müller EE,Salvatoni A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Sleep behavior is changing toward shorter sleep duration and a later chronotype. It results in a sleep debt that is acquitted on work-free days, inducing a small but recurrent sleep misalignment each week, referred to as "social jetlag". These sleep habits could affect health through misalignment with circad...

journal_title：European journal of endocrinology

authors： Larcher S,Gauchez AS,Lablanche S,Pépin JL,Benhamou PY,Borel AL

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To identify chromosomal gains and losses in sporadic parathyroid adenomas (PAs). METHODS:Fourteen sporadic PAs were studied by comparative genomic hybridization (CGH). RESULTS:The fourteen studied PAs showed chromosomal imbalances. All cases except one exhibited two or more abnormalities. Chromosomal gains ...

journal_title：European journal of endocrinology

authors： Garcia JL,Tardio JC,Gutierrez NC,Gonzalez MB,Polo JR,Hernandez JM,Menarguez J

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:Local 5'-deiodination of l-thyroxine (T(4)) to active thyroid hormone 3,3',5-tri-iodothyronine (T(3)) catalyzed by the two 5'-deiodinase enzymes (D1 and D2) regulates various T(3)-dependent functions in the anterior pituitary and has been well studied in rodents. Only limited information about deiodinase expr...

journal_title：European journal of endocrinology

authors： Baur A,Buchfelder M,Köhrle J

更新日期：2002-08-01 00:00:00

abstract：AIM:It is widely known that inflammation is related to type 2 diabetes (T2D), but few studies have shown a direct relationship between the immune system and T2D using a reliable biomarker. Neutrophil:lymphocyte ratio (NLR) is an easy-to-analyze inflammation biomarker, but few studies have assessed the relationship betw...

journal_title：European journal of endocrinology

authors： Guo X,Zhang S,Zhang Q,Liu L,Wu H,Du H,Shi H,Wang C,Xia Y,Liu X,Li C,Sun S,Wang X,Zhou M,Huang G,Jia Q,Zhao H,Song K,Niu K

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To test further the hypothesis that autosomal dominant neurohypophyseal diabetes insipidus (adFNDI) is caused by heterozygous mutations in the vasopressin-neurophysin II (AVP-NPII) gene that exert a dominant negative effect by producing a precursor that misfolds, accumulates and eventually destroys the neuros...

journal_title：European journal of endocrinology

authors： Rutishauser J,Kopp P,Gaskill MB,Kotlar TJ,Robertson GL

更新日期：2002-05-01 00:00:00

abstract：:Human growth hormone (GH) exists in a variety of isoforms. In the pituitary, the most abundant isoform is 22-kD GH (22 K GH), while other isoforms (non-22 K GH) are present in variable amounts. In human plasma, the GH heterogeneity contributes to the wide variability in GH levels measured by different immunoassays. Th...

journal_title：European journal of endocrinology

authors： Boguszewski CL,Hynsjö L,Johannsson G,Bengtsson BA,Carlsson LM

更新日期：1996-11-01 00:00:00

abstract：:Approximately 15 million babies are born preterm across the world every year, with less than 37 completed weeks of gestation. Survival rates increased during the last decades with the improvement of neonatal care. With premature birth, babies are deprived of the intense intrauterine growth phase, and postnatal growth ...

journal_title：European journal of endocrinology

authors： Boguszewski MCDS,Cardoso-Demartini AA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Adult height deficit seen in Turner syndrome (TS) originates, in part, from growth retardation in utero and throughout the first 3 years of life. Earlier diagnosis enables earlier therapeutic intervention, such as with recombinant human GH (r-hGH), which may help to prevent growth retardation. In this open-la...

journal_title：European journal of endocrinology

authors： Linglart A,Cabrol S,Berlier P,Stuckens C,Wagner K,de Kerdanet M,Limoni C,Carel JC,Chaussain JL,French Collaborative Young Turner Study Group.

更新日期：2011-06-01 00:00:00

abstract：INTRODUCTION:In an animal model of acromegaly (PEPCK-hGH transgenic mice), low systemic levels of ghrelin have been observed compared with normal mice. We hypothesized that systemic circulating ghrelin levels are also decreased in humans with active acromegaly and that the contribution of central ghrelin production to ...

journal_title：European journal of endocrinology

authors： van der Toorn FM,Janssen JA,de Herder WW,Broglio F,Ghigo E,van der Lely AJ

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To assess the individuals' thyroid volume changes after the mandatory nationwide iodine fortification (IF) program in two Danish areas with different iodine intake at baseline (Copenhagen, mild iodine deficiency (ID) and Aalborg, moderate ID). DESIGN:A longitudinal population-based study (DanThyr). METHODS:...

journal_title：European journal of endocrinology

authors： Krejbjerg A,Bjergved L,Pedersen IB,Carlé A,Jørgensen T,Perrild H,Ovesen L,Rasmussen LB,Knudsen N,Laurberg P

更新日期：2014-03-08 00:00:00

abstract：BACKGROUND:Betaglycan is a membrane-anchored proteoglycan involved in mediating the passage of transforming growth factor-beta (TGF-beta), inhibin and activin activities into cells. TGF-beta and inhibin-related proteins are growth factors that are expressed by several tIssues and in pregnancy. They have a function in m...

journal_title：European journal of endocrinology

authors： Ciarmela P,Florio P,Toti P,Grasso D,Santopietro R,Tosi P,Petraglia F

更新日期：2003-11-01 00:00:00

abstract：:The mineralocorticoid receptor (MR), a member of the steroid receptor family, acts as a transcription factor and mediates both aldosterone and cortisol effects. Aldosterone specificity in some tissues results from the inactivation of competing cortisol into cortisone by 11beta-hydroxysteroid dehydrogenase. In other ti...

journal_title：European journal of endocrinology

authors： Wickert L,Watzka M,Bolkenius U,Bidlingmaier F,Ludwig M

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:The role of preoperative localisation of abnormal parathyroid glands remains controversial but is particularly relevant to the management of patients with recurrent or persistent hyperparathyroidism and familial syndromes. We report our experience of the use of selective parathyroid venous sampling (PVS) in t...

journal_title：European journal of endocrinology

authors： Ogilvie CM,Brown PL,Matson M,Dacie J,Reznek RH,Britton K,Carpenter R,Berney D,Drake WM,Jenkins PJ,Chew SL,Monson JP

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Polycystic ovarian syndrome (PCOS) is associated with skeletal muscle insulin resistance (IR), which has been linked to decreased mitochondrial function. We measured mitochondrial respiration in lean and obese women with and without PCOS using high-resolution respirometry. METHODS:Hyperinsulinemic-euglycemic...

journal_title：European journal of endocrinology

authors： Rabøl R,Svendsen PF,Skovbro M,Boushel R,Schjerling P,Nilas L,Madsbad S,Dela F

更新日期：2011-10-01 00:00:00

abstract：UNLABELLED:Chronic exposure to hypercortisolism has significant impact on patient's health and health-related quality of life (HRQoL), as demonstrated with generic questionnaires. We have developed a disease-generated questionnaire to evaluate HRQoL in patients with Cushing's syndrome (CS; CushingQoL). OBJECTIVE:Valid...

journal_title：European journal of endocrinology

authors： Webb SM,Badia X,Barahona MJ,Colao A,Strasburger CJ,Tabarin A,van Aken MO,Pivonello R,Stalla G,Lamberts SW,Glusman JE

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Hypochondroplasia (HCH) is a skeletal dysplasia inherited in an autosomal dominant manner due, in most cases, to mutations in the fibroblast growth factor receptor 3 (FGFR3). Acanthosis nigricans (AN) is a velvety and papillomatous pigmented hyperkeratosis of the skin, which has been recognized in some genet...

journal_title：European journal of endocrinology

authors： Castro-Feijóo L,Loidi L,Vidal A,Parajes S,Rosón E,Alvarez A,Cabanas P,Barreiro J,Alonso A,Domínguez F,Pombo M

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To estimate morbidity in Denmark in all patients with GH deficiency (GHD). DESIGN:Morbidity was analyzed in 1794 GHD patients and 8014 controls matched on age and gender. All records in the GHD patients were studied and additional morbidity noted. Diagnoses and dates of admissions were identified in the Nati...

journal_title：European journal of endocrinology

authors： Stochholm K,Laursen T,Green A,Laurberg P,Andersen M,Kristensen LØ,Feldt-Rasmussen U,Christiansen JS,Frydenberg M,Gravholt CH

更新日期：2008-04-01 00:00:00

abstract：:X-linked adrenoleucodystrophy (ALD) has been shown to be one of the most frequent causes of Addison's disease in men. It is characterized by an impaired peroxisomal beta-oxidation of very long chain fatty acids and is associated with mutations of the ALD gene resulting in a defective peroxisomal membrane transport pro...

journal_title：European journal of endocrinology

authors： Korenke GC,Roth C,Krasemann E,Hüfner M,Hunneman DH,Hanefeld F

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:Patients with type 2 diabetes mellitus (T2DM) have an increased risk of fractures and thiazolidinediones (TZDs) increase this risk. TZDs stimulate the expression of sclerostin, a negative regulator of bone formation, in vitro. Abnormal sclerostin production may, therefore, be involved in the pathogenesis of i...

journal_title：European journal of endocrinology

authors： van Lierop AH,Hamdy NA,van der Meer RW,Jonker JT,Lamb HJ,Rijzewijk LJ,Diamant M,Romijn JA,Smit JW,Papapoulos SE

更新日期：2012-04-01 00:00:00