1992 National Clinical Pharmacy Services Study.

abstract：:We cared for a 4-year-old patient who had undergone orthotopic liver transplantation and was placed on a ventilator for respiratory distress associated with Pneumocystis carinii pneumonia. The neuromuscular blocking agent pancuronium bromide 1.0-1.2 mg every hour as needed was used to facilitate artificial ventilation...

journal_title：Pharmacotherapy

authors： Haas JL,Shaefer MS,Miwa LJ,Wood RP,Shaw BW Jr

更新日期：1989-01-01 00:00:00

abstract：:Serious gram-positive infections present an increasingly common therapeutic dilemma. Combination antimicrobial regimens (e.g., linezolid with rifampin) aimed at improving bacterial eradication and preventing resistance are often used; however, most data supporting this treatment strategy are not from randomized contro...

journal_title：Pharmacotherapy

authors： Gebhart BC,Barker BC,Markewitz BA

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:Vancomycin (VAN) is associated with an increased risk of acute kidney injury (AKI). Evidence is conflicting regarding the risk of AKI when VAN is combined with an antipseudomonal β-lactam. OBJECTIVES:To determine the comparative incidence of AKI when VAN is combined with piperacillin-tazobactam (PTZ) or m...

journal_title：Pharmacotherapy

authors： Robertson AD,Li C,Hammond DA,Dickey TA

更新日期：2018-12-01 00:00:00

abstract：:The objective of this study was to describe the postinduction clearance of carbamazepine (CBZ) in adult psychiatric patients by population pharmacokinetic analysis using the NONMEM program. Specifically, an estimate of CBZ clearance and insight into the effect of common patient characteristics on clearance were sought...

journal_title：Pharmacotherapy

authors： Martin ES 3rd,Crismon ML,Godley PJ

更新日期：1991-01-01 00:00:00

abstract：:Acute myeloid leukemia (AML), a clonal hematologic malignancy that results in bone marrow failure, is the most common acute leukemia in adults (median age of diagnosis 67 yrs), and treatment options, especially in the elderly population, are limited. Induction chemotherapy with 7 + 3, the combination of continuous-inf...

journal_title：Pharmacotherapy

authors： Stansfield LC,Pollyea DA

更新日期：2017-12-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the effects of mild-to-moderate induced hypothermia-a neuroprotectant and/or therapeutic strategy for the management of intracranial hypertension in neurologically injured patients-on the pharmacokinetics of aminoglycoside therapy. DESIGN:Pharmacokinetic analysis. SETTING:Critical care un...

journal_title：Pharmacotherapy

authors： Mercer JM,Neyens RR

更新日期：2010-07-01 00:00:00

abstract：:The use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) has significantly reduced morbidity and mortality across the continuum of vascular disease. The utilization of these agents, however, remains suboptimal. The drugs are not prescribed in many patients because of concerns ...

journal_title：Pharmacotherapy

authors： Epstein BJ

更新日期：2004-05-01 00:00:00

abstract：:Struvite calculi result from urinary tract infections secondary to urease-producing bacteria. To prevent recurrent infection and stone formation complete removal of struvite calculi is recommended. Two illustrative reports of patients with renal struvite calculi are presented in which 10% hemiacidrin (Renacidin) irrig...

journal_title：Pharmacotherapy

authors： Massaro FJ,Weiner B,Sant GR,Meares EM Jr

更新日期：1983-11-01 00:00:00

abstract：:An area of unidirectional conduction block is one requirement for reentrant arrhythmias to occur. Functional block caused by dispersion of repolarization and refractoriness is the most probable mechanism of drug-induced unidirectional conduction block. We assessed the effects of lidocaine on spatial dispersion of myoc...

journal_title：Pharmacotherapy

authors： Sims JJ,Winecoff AP,Ujhelyi MR

更新日期：1997-11-01 00:00:00

abstract：:Fluconazole is a commonly prescribed antifungal agent with a favorable safety profile. A patient experienced agranulocytosis and eosinophilia associated with the drug. Similar bone marrow-suppressive effect due to the azoles is rarely described in the English-language literature. ...

journal_title：Pharmacotherapy

authors： Wong-Beringer A,Shriner K

更新日期：2000-04-01 00:00:00

abstract：STUDY OBJECTIVE:To quantify the relative risk of cardiovascular events associated with microalbuminuria in patients with both diabetes mellitus and hypertension. DESIGN:A structured literature search from January 1990-December 2002 using MEDLINE, IPA, and CINAHL. MEASUREMENTS AND MAIN RESULTS:We identified original s...

journal_title：Pharmacotherapy

authors： Park HY,Schumock GT,Pickard AS,Akhras K

更新日期：2003-12-01 00:00:00

abstract：:A 32-year-old woman with a history of deep vein thrombosis (DVT), steroid-dependent ulcerative colitis, and osteoporosis was prescribed azathioprine for a steroid-sparing effect. Stable, therapeutic international normalized ratios (INRs) were obtained with warfarin 35 mg/week during a 6-week postpartum course to treat...

journal_title：Pharmacotherapy

authors： Havrda DE,Rathbun S,Scheid D

更新日期：2001-03-01 00:00:00

abstract：:Personalized medicine has been a mainstay and in practice in transplant pharmacotherapy since the advent of the field. Decisions pertaining to the diagnosis, selection, and monitoring of transplant pharmacotherapy are aimed toward the individual, the allograft, and the overall immunologic needs of the patient. Recent ...

journal_title：Pharmacotherapy

authors： Maldonado AQ,West-Thielke P,Joyal K,Marks CR

更新日期：2020-11-06 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) has become the most prevalent cause of acute hematogenous osteomyelitis (AHO) in pediatric patients. This increase in MRSA is due to the rise in community-acquired MRSA. Therefore, it is important that clinicians are aware of the various and upcoming therapies that co...

journal_title：Pharmacotherapy

authors： DeRonde KJ,Girotto JE,Nicolau DP

更新日期：2018-10-01 00:00:00

abstract：:Ongoing improvements in immunosuppression and posttransplantation care have dramatically improved patient and graft outcomes after transplantation. The frequency of graft loss due to acute rejection has declined considerably as a result of the availability of a variety of more potent immunosuppressive agents and proba...

journal_title：Pharmacotherapy

authors： Lo A,Alloway RR

更新日期：2002-03-01 00:00:00

abstract：:Limitations of traditional anticoagulants have led to the need for structured services to provide anticoagulation monitoring. Anticoagulation management services have historically filled this role. Novel antithrombotic agents currently in development have the potential to improve on the limitations of vitamin K antago...

journal_title：Pharmacotherapy

authors： Nutescu EA,Spinler SA,Dager WE,Bussey HI

更新日期：2004-10-01 00:00:00

abstract：:The U.S. population continues to experience an alarmingly high rate of unintended pregnancies that have an impact on individual families and society alike. Lack of effective contraception accounts for most unintended pregnancies, along with incorrect use of contraceptives. The most common reversible contraceptive meth...

journal_title：Pharmacotherapy

authors： Rafie S,McIntosh J,Shealy KM,Borgelt LM,Forinash A,Shrader SP,Koepf ER,McClendon KS,Griffin BL,Horlen C,Karaoui LR,Rowe EL,Lodise NM,Wigle PR

更新日期：2014-09-01 00:00:00

abstract：:It is well recognized that drug absorption from the gastrointestinal tract is influenced by gastric and intestinal motility, surface area available for absorption, and physicochemical properties of the drug. Disease and surgery have been shown to alter these factors. Consequently, drug absorption can be altered as wel...

journal_title：Pharmacotherapy

authors： Gubbins PO,Bertch KE

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To estimate the effect of a triplicate prescription policy on administration of benzodiazepines and possible substitute drugs in nursing home residents during 1994-1995. DESIGN:Retrospective cross-sectional study SETTING:Medicare- and Medicaid-certified nursing homes in five states: New York, which has a po...

journal_title：Pharmacotherapy

authors： VanHaaren AM,Lapane KL,Hughes CM

更新日期：2001-10-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the impact of having an antimicrobial allergy label in the medical record on clinical outcomes in hospitalized patients. DESIGN:Retrospective cohort study. SETTING:Urban academic teaching hospital. PATIENTS:A total of 11,872 adults admitted to nonsurgical patient care wards who received ...

journal_title：Pharmacotherapy

authors： Charneski L,Deshpande G,Smith SW

更新日期：2011-08-01 00:00:00

abstract：:Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (sALCL), which is a subtype of non-Hodgkin lymphoma, are relatively uncommon lymphoproliferative types of cancer. These malignancies are highly curable with initial treatment. Nonetheless, some patients are refractory to or relapse after first- and seco...

journal_title：Pharmacotherapy

authors： Newland AM,Li JX,Wasco LE,Aziz MT,Lowe DK

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Neurocritically ill patients have clinically significant alterations in pharmacokinetic parameters of renally eliminated medications that may result in subtherapeutic plasma and cerebrospinal fluid antibiotic concentrations. METHODS:We conducted a prospective randomized open-label study of adult neurocriticall...

journal_title：Pharmacotherapy

authors： Kassel LE,Van Matre ET,Foster CJ,Fish DN,Mueller SW,Sherman DS,Wempe MF,MacLaren R,Neumann RT,Kiser TH

更新日期：2018-09-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the efficacy, safety, and costs of rabbit antithymocyte globulin (TMG) induction in patients who received kidney transplants from living unrelated donors. DESIGN:Retrospective cohort study. SETTING:Large academic medical center. PATIENTS:Eighty-seven patients who received kidney transplan...

journal_title：Pharmacotherapy

authors： Miller JT,Collins CD,Stuckey LJ,Luan FL,Englesbe MJ,Magee JC,Park JM

更新日期：2009-10-01 00:00:00

abstract：:Hyponatremia is the most common electrolyte disorder encountered in clinical practice and is associated with significant morbidity and mortality. Clinical consequences of hyponatremia include neurologic dysfunction, decreased mental function, cerebral edema, gait disturbances and falls, osteoporosis, and fractures. Hy...

journal_title：Pharmacotherapy

authors： Patterson JH

更新日期：2011-05-01 00:00:00

abstract：:The frequency of type 2 diabetes mellitus is increasing at an alarming rate. Prediabetes, also referred to as impaired glucose tolerance (IGT) and/or impaired fasting glucose, is a major risk factor for development of type 2 diabetes mellitus. In addition, IGT has been associated with an increased risk of cardiovascul...

journal_title：Pharmacotherapy

authors： Irons BK,Mazzolini TA,Greene RS

更新日期：2004-03-01 00:00:00

abstract：STUDY OBJECTIVES:To determine changes in bone mineral density (BMD) and T scores of patients after 2 years of teriparatide therapy, and to determine the number of fractures that occurred during therapy. DESIGN:Prospective, observational study. SETTING:Pharmacist-run teriparatide clinic in a private-practice endocrino...

journal_title：Pharmacotherapy

authors： Stroup JS,Rivers SM,Abu-Baker AM,Kane MP

更新日期：2007-06-01 00:00:00

abstract：:To determine salary and selected fringe benefits of members of the Ambulatory Care Practice and Research Network of the American College of Clinical Pharmacy, we developed a self-administered questionnaire that surveyed demographic information, schooling and training, academic appointments, yearly salary (as of Februa...

journal_title：Pharmacotherapy

authors： Anastasio GD,Shaughnessy AF

更新日期：1997-05-01 00:00:00

abstract：:Clinicians are increasingly faced with the need to identify, treat, and counsel patients regarding psychotropic drug-induced sexual dysfunction. Antipsychotic and antidepressant drugs have both rational mechanisms to explain their effects on sexual function and established literature documenting these effects. The age...

journal_title：Pharmacotherapy

authors： Gutierrez MA,Stimmel GL

更新日期：1999-07-01 00:00:00

abstract：:Aortic stenosis (AS) is the most common form of valvular heart disease. A detailed diagnostic workup is necessary to promptly stage and classify disease severity to determine optimal management. Medical therapy and valvuloplasty are options that fail to delay or reverse disease progression. Surgical aortic valve repla...

journal_title：Pharmacotherapy

authors： Kalich BA,Allender JE,Hollis IB

更新日期：2018-01-01 00:00:00

abstract：:The effect of treatment for hepatitis C viral infection on hemoglobin A(1c) (A1C) levels is not well described in the literature. We describe a 59-year-old man with type 2 diabetes mellitus whose A1C level became falsely low when ribavirin and peginterferon alfa-2b therapy were started for treatment of hepatitis C. Af...

journal_title：Pharmacotherapy

authors： Gross BN,Cross LB,Foard JC,Wood YA

更新日期：2009-01-01 00:00:00