Impairment of the postural venoarteriolar reflex in aged individuals.

Abstract:

:The venoarteriolar vasoconstriction reflex plays a major role in the prevention of leg oedema in the upright position in man. We studied the venoarteriolar vasoconstriction reflex with laser Doppler flowmetry in young (21 subjects, age 17-27) and very old (20 subjects, age 75-100) healthy volunteers. In the group of young volunteers, after lowering of the lower extremity 50 cm below the heart level, cutaneous blood flux decreased to 16.6% of the baseline, whereas in the group of old persons the venoarteriolar reflex was impaired and the flux decreased only to 29.2%. The difference between the two groups was statistically significant (p < 0.001). These results may explain the increased prevalence of postural oedema in old people.

journal_name

Acta Derm Venereol

authors

Gniadecka M,Gniadecki R,Serup J,Søndergaard J

doi

10.2340/0001555574194196

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

194-6

issue

3

eissn

0001-5555

issn

1651-2057

journal_volume

74

pub_type

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