Abstract:
:The venoarteriolar vasoconstriction reflex plays a major role in the prevention of leg oedema in the upright position in man. We studied the venoarteriolar vasoconstriction reflex with laser Doppler flowmetry in young (21 subjects, age 17-27) and very old (20 subjects, age 75-100) healthy volunteers. In the group of young volunteers, after lowering of the lower extremity 50 cm below the heart level, cutaneous blood flux decreased to 16.6% of the baseline, whereas in the group of old persons the venoarteriolar reflex was impaired and the flux decreased only to 29.2%. The difference between the two groups was statistically significant (p < 0.001). These results may explain the increased prevalence of postural oedema in old people.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Gniadecka M,Gniadecki R,Serup J,Søndergaard Jdoi
10.2340/0001555574194196subject
Has Abstractpub_date
1994-05-01 00:00:00pages
194-6issue
3eissn
0001-5555issn
1651-2057journal_volume
74pub_type
杂志文章abstract::Blood glutathione-peroxidase (GSH-Px) was determined in 61 healthy subjects and 506 patients with various skin disorders. Depressed levels were observed in patients with psoriasis, eczema, atopic dermatitis, vasculitis, mycosis fungoides and dermatitis herpetiformis. Low values of GSH-Px were also found in some patien...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Using the mouse, photoallergy to the antiarrhythmic agent quinidine could be induced following systemic administration. After pretreatment with cyclophosphamide 150 mg/kg, groups of 5-10 mice were injected i.p. with quinidine chloride 100 mg/kg on 2 consecutive days, followed by exposure of shaved abdominal skin to UV...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Remission of psoriatic lesions was induced when the lesions were firmly pressed with a plastic cap held in place by an elastic bandage for 24 h or stretched with a negative pressure of 200 mmHg for 2 h. Seven out of 10 patients showed a clinical improvement of the treated psoriatic lesions. These lesions cleared withi...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:102340/0001555570176179
更新日期:1990-01-01 00:00:00
abstract::The area of UV erythema produced by a small beam head was found to increase with increasing doses. The aim was to investigate whether measurement of the area could be a more useful indicator of UV-induced damage than classic visual grading. Topical pretreatment with all-trans retinoic acid (tretinoin) and betamethason...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555573273275
更新日期:1993-08-01 00:00:00
abstract::32 women complaining of diffuse alopecia were assessed by a psychiatrist, and daily hair loss and root counts were measured and compared with control women. Seven of the 32 women had severe marital difficulties, and 2 of these were overtly depressed. In these 7 women, daily hair loss and telogen counts did not differ ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::One of the prepolymers used in Ultraviolet (UV) curing ink formulations is acrylated polyester. The prepolymer investigated is a dimethacrylated polyester, thus a saturated polyester terminated with methacrylic groups. In conventional UV-curing coatings the prepolymer commonly used is an unsaturated polyester. Three o...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Familial progressive hyperpigmentation is rarely described in the literature. We report on five patients from three different families presenting with a peculiar progressive pigmentary disorder. The patients show a progressive diffuse, partly blotchy, hyperpigmentation, intermixed with scattered small hypopigmented ma...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/00015550310005780
更新日期:2004-01-01 00:00:00
abstract::We describe here 4 patients with Sézary syndrome masquerading as adult-onset atopic dermatitis. The patients presented with a clinical picture compatible with wide-spread atopic dermatitis and did not fulfil the criteria for Sézary syndrome (lack of lymphoadenopathy and blood involvement, skin histology without presen...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-1149
更新日期:2011-09-01 00:00:00
abstract::The aromatic retinoids etretinate and acitretin are widely used in the systemic treatment of severe psoriasis. The purpose of the present investigation was to further elucidate the mode of action of acitretin on abnormal keratinization and epidermal hyperproliferation in an in vivo model. Studies on the interference o...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/000155557669
更新日期:1996-01-01 00:00:00
abstract::Abnormal expression of cell adhesion molecules and related proteins has been observed in various carcinoma cells. We compared expression patterns of desmosomal cadherins, E-cadherin, and cytoplasmic plaque proteins of four different human squamous cell carcinoma cell lines and in vivo squamous cell carcinoma cells wit...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555576417420
更新日期:1996-11-01 00:00:00
abstract::The principles behind the primary localization of lesions in fixed drug eruption are still unknown. Studies investigating the predilection areas indicated drug-related, trauma-related or inflammation-related specific site involvement in fixed drug eruption. This study presents new findings of primary site involvement ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0307
更新日期:2007-01-01 00:00:00
abstract::The possibility that topically-applied minoxidil might affect the growth cycle of hair follicles was studied in inbred Herston white mice and HRA/Skh1 hairless mice. In the normal follicular cycle, the anagen or growth phase can be followed by autoradiographic demonstration of [3H]thymidine uptake in proliferating mat...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Data regarding the efficacy and safety of methotrexate (MTX) in adults with localized scleroderma (LoS) is scarce. This study gathered data from a retrospective cohort of adult patients with LoS (n?=?107), treated with MTX (1993-2015). MTX drug survival and predictors thereof were analysed. After 1 and 2 years, 26% an...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2411
更新日期:2016-11-02 00:00:00
abstract::Atopic dermatitis (AD) and impetigo are skin conditions where bacterial colonisation and infection, especially with Staphylococcus aureus play an important role. We compared skin bacterial population, resistance patterns and choice of antimicrobial agents in patients diagnosed with AD and impetigo during 2005 and 2011...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-1996
更新日期:2015-05-01 00:00:00
abstract::It has been suggested that prolonged antigenic stimulation contributes to the development of epidermotropic cutaneous T cell lymphoma (CTCL), mycosis fungoides and Sézary syndrome, characterized by a cutaneous infiltration of proliferating helper T cells. Since Epstein-Barr virus (EBV) antibodies were increased in CTC...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555574355357
更新日期:1994-09-01 00:00:00
abstract::Balanoposthitis is an inflammatory disorder of the prepuce and glans penis. Microbes involved in balanoposthitis have been investigated, but no single study has covered the growth of both bacteria, Candida and Malassezia. We report here the prevalence of these microbes in 100 patients with balanoposthitis and in 26 co...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0478
更新日期:2008-01-01 00:00:00
abstract::Sensitive skin is a clinical syndrome characterized by the occurrence of unpleasant sensations, such as pruritus, burning or pain, in response to various factors, including skincare products, water, cold, heat, or other physical and/or chemical factors. Although these symptoms suggest inflammation and the activation o...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2235
更新日期:2016-03-01 00:00:00
abstract::Biopsies obtained from both the perilesional areas and clinically uninvolved skin of patients with pemphigus vulgaris (PV) were studied for antigen-presenting cell and lymphocyte phenotype and/or activation phenotype using monoclonal antibodies in avidin-biotin-peroxidase complex staining. Perilesional PV skin contain...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::In order to establish whether or not here is an association between cancer and intense growth of seborrheic keratosis, the so-called Leser-Trelat sign, we conducted a case control study in which the number and features of seborrheic keratosis in 82 patients with recent solid tumours, were compared with 82 age- and sex...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Systemic contact dermatitis may occur in contact-sensitized individuals when they are exposed to haptens orally, transcutaneously, intravenously or by inhalation. We report the case of a woman developing a diffuse skin eruption after the topical use of Rhus toxicodendron alcoholic extract and the oral introduction of ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/00015550410023293
更新日期:2004-01-01 00:00:00
abstract::In this prospective study, 51 patients suffering from psoriasis and ichthyosis were treated with acitretin for 2 years. The average dose was 0.5 mg/kg/day. We have evaluated the efficacy and side effects, focusing on skeletal side effects. X-ray examinations were done before treatment and after 1 and 2 years. Forty-fi...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:102340/0001555572445448
更新日期:1992-11-01 00:00:00
abstract::Two female patients suffering from progressive systemic sclerosis (PSS) of generalized type were treated with estriol for 10 months. Although complete cure was not achieved, considerable beneficial effects were observed in these patients, but no serious side effects. Thus, skin softening was observed on all involved p...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The ultrastructural localization of copper and zinc superoxide dismutase (Cu,Zn-SOD) and manganese superoxide dismutase (Mn-SOD) was investigated in normal human skin by the post-embedding immunogold staining method. Epidermal keratinocytes were positive for both Cu,Zn-SOD and Mn-SOD. The Cu,Zn-SOD was predominantly l...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555734145
更新日期:1993-02-01 00:00:00
abstract::The expression of the transglutaminase I in human anagen hair follicles was studied by an immunohistochemical staining. In the bulbar and suprabulbar portions of anagen hair follicles, transglutaminase I was detected on the hair cuticle and the three layers of the inner root sheath. Subsequently, the positive staining...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555575190192
更新日期:1995-05-01 00:00:00
abstract::The releasability of arachidonic acid-derived inflammatory mediators (eicosanoids) from peripheral blood leukocytes has been tested in patients with atopic eczema and healthy, non-atopic controls. Spontaneous and stimulated release of prostaglandin E2 (PGE2), leukotriene B4 (LTB4) and leukotriene C4 (LTC4) has been me...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Papillon-Lefèvre syndrome is an autosomal recessive disorder characterized by palmoplantar hyperkeratosis and aggressive periodontitis. The aim of the study was to identify underlying cathepsin C mutations in 39 subjects with Papillon-Lefèvre syndrome and to explore any phenotypic associations. Genotyping and mutation...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/00015550510011619
更新日期:2006-01-01 00:00:00
abstract::Scalp psoriasis is associated with hair loss and an increased telogen/anagen ratio. Topical treatment of scalp psoriasis (with corticosteroids, dithranol or tar) results in decreased scaling, induration and erythema of the plaques. Calcipotriol is effective in the treatment of psoriasis vulgaris. However, the potent g...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2340/0001555575388390
更新日期:1995-09-01 00:00:00
abstract::A simple non-radioactive technique is described. The corneal layers were stained with 5% dansyl chloride ointment during 24-48 h of occlusion. The number of newly formed corneal layers were counted on sections from punch biopsies obtained at various intervals after the staining. The rate of formation is given as layer...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::We set out to show that the assumption is incorrect that continuous treatment with cyclosporin is necessary in psoriasis, as this tenet forms a basis for current recommended treatment regimens. Sixty patients with mild to moderate plaque psoriasis were allocated at random to treatment with oral cyclosporin 5 mg/kg/day...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2340/00015555756569
更新日期:1995-01-01 00:00:00
abstract::Becker's naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder. Immunohistochemistry showed that epidermal expression of androgen receptors, oestrogen receptors (α, β) and progesterone receptors was higher in skin lesions of Be...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-2986
更新日期:2018-10-10 00:00:00