Follow-up and management of differentiated thyroid carcinoma: a European perspective in clinical practice.

Abstract:

:As differentiated (follicular and papillary) thyroid cancer (DTC) may recur years after initial treatment, follow-up of patients with DTC is long term. However, this population has changed, with more individuals being discovered at an earlier stage of disease, so that previous follow-up protocols based mostly on data from high-risk patients no longer apply. We have proposed, in a previous issue of this Journal, an improved protocol for the follow-up of low-risk patients with DTC based on the findings of recent studies. We report here the case of a paradigmatic patient with papillary thyroid carcinoma, with the goal of illustrating the benefits of applying this algorithm in routine clinical practice. We also offer expanded and additional comments on various issues in the management of DTC.

journal_name

Eur J Endocrinol

authors

Schlumberger M,Pacini F,Wiersinga WM,Toft A,Smit JW,Sanchez Franco F,Lind P,Limbert E,Jarzab B,Jamar F,Duntas L,Cohen O,Berg G

doi

10.1530/eje.0.1510539

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

539-48

issue

5

eissn

0804-4643

issn

1479-683X

journal_volume

151

pub_type

杂志文章
  • Sleep-wake and melatonin pattern in craniopharyngioma patients.

    abstract:OBJECTIVE:To assess the influence of craniopharyngioma or consequent surgery on melatonin secretion, and the association with fatigue, sleepiness, sleep pattern and sleep quality. DESIGN:Cross-sectional study. METHODS:A total of 15 craniopharyngioma patients were individually matched to healthy controls. In this stud...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-13-1025

    authors: Pickering L,Jennum P,Gammeltoft S,Poulsgaard L,Feldt-Rasmussen U,Klose M

    更新日期:2014-06-01 00:00:00

  • Effect of ovariectomy and steroid hormone replacement on the recovery of arterial blood pressure following haemorrhage in anaesthetized Brattleboro rats.

    abstract::There is increasing evidence that ovarian steroids inhibit vascular responsiveness to the neurohypophysial hormone vasopressin. The present study examined the recovery of the arterial blood pressure following a single (2 ml/100 g body weight) haemorrhage in ovariectomized (OVX) Brattleboro rats with hereditary hypotha...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.0.1360330

    authors: Morrissey SE,Edwards TJ,Wilson KJ,Whitehead SA,Laycock JF

    更新日期:1997-03-01 00:00:00

  • ENDOCRINE TUMOURS: Calcitonin in thyroid and extra-thyroid neuroendocrine neoplasms: the two-faced Janus.

    abstract::An increased calcitonin serum level is suggestive of a medullary thyroid cancer (MTC), but is not pathognomonic. The possibility of false positives or other calcitonin-secreting neuroendocrine neoplasms (NENs) should be considered. Serum calcitonin levels are generally assessed by immunoradiometric and chemiluminescen...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1530/EJE-20-0506

    authors: Giannetta E,Guarnotta V,Altieri B,Sciammarella C,Guadagno E,Malandrino P,Puliani G,Feola T,Isidori AM,Colao AAL,Faggiano A

    更新日期:2020-12-01 00:00:00

  • Androgen receptor gene GGN repeat length and reproductive characteristics in young Swedish men.

    abstract:BACKGROUND:The human androgen receptor (AR) gene contains two polymorphisms of CAG and GGN repeats respectively. The GGN repeat function is still largely unknown and to date there are no in vivo data on this segment with respect to the general population. METHODS:We investigated the impact of CAG and GGN repeats on ma...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.1.02204

    authors: Lundin KB,Giwercman YL,Rylander L,Hagmar L,Giwercman A

    更新日期:2006-08-01 00:00:00

  • The clinical, pathological, and genetic features of familial isolated pituitary adenomas.

    abstract::Pituitary adenomas occur in a familial setting in multiple endocrine neoplasia type 1 (MEN1) and Carney's complex (CNC), which occur due to mutations in the genes MEN1 and PRKAR1A respectively. Isolated familial somatotropinoma (IFS) is also a well-described clinical syndrome related only to patients with acrogigantis...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1530/EJE-07-0348

    authors: Beckers A,Daly AF

    更新日期:2007-10-01 00:00:00

  • Anthropometric factors have significant influence on the outcome of the GHRH-arginine test: establishment of normative data for an automated immunoassay specifically measuring 22 kDa human growth hormone.

    abstract:CONTEXT:Adult growth hormone (GH) deficiency (GHD) is diagnosed by provocative testing of GH secretion. OBJECTIVE:To improve the diagnostic accuracy of GH-releasing hormone (GHRH) plus arginine (GARG) testing, we evaluated the influence of age, BMI and sex and established normative data for an automatic immunoassay sp...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-16-0668

    authors: Deutschbein T,Bidlingmaier M,Schopohl J,Strasburger CJ,Petersenn S

    更新日期:2017-03-01 00:00:00

  • Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome.

    abstract:OBJECTIVE:The insulin-resistant state of the polycystic ovary syndrome (PCOS) was found to be associated with a decreased glucose transporter GLUT4 expression in the insulin target tissues. This study was performed to explore whether the well-known clinical, hormonal and metabolic efficacy of metformin or rosiglitazone...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,随机对照试验

    doi:10.1530/EJE-07-0857

    authors: Jensterle M,Janez A,Mlinar B,Marc J,Prezelj J,Pfeifer M

    更新日期:2008-06-01 00:00:00

  • PRE-TERM BIRTH IN WOMEN EXPOSED TO CUSHING'S DISEASE: THE BABY-CUSH STUDY.

    abstract::Design Hypercortisolism during pregnancy is a risk factor for prematurity. Long-term exposure to hypercortisolism may lead to permanent comorbidities, such as hypertension or diabetes, even after remission. Our aim was to determine whether women with a history of Cushing's disease (and being eu-, hypo- or hypercortiso...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-20-1224

    authors: Hochman C,Cristante J,Geslot A,Salenave S,Sonnet E,Briet C,Bachelot A,Chevalier N,Gilly O,Brue T,Hadjadj S,Kerlan V,Chanson P,Vezzosi D,Chabre O,Drui DD,Castinetti FF

    更新日期:2021-01-01 00:00:00

  • Inadequacies of glucocorticoid replacement and improvements by physiological circadian therapy.

    abstract::Patients with adrenal insufficiency need lifelong glucocorticoid replacement, but many suffer from poor quality of life, and overall there is increased mortality. Moreover, it appears that use of glucocorticoids at the higher end of the replacement dose range is associated with increased risk for cardiovascular and me...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1530/EJE-08-0874

    authors: Debono M,Ross RJ,Newell-Price J

    更新日期:2009-05-01 00:00:00

  • Etiology, baseline characteristics, and biochemical diagnosis of GH deficiency in the adult: are there regional variations?

    abstract::Previous work has examined potential links between the etiology of GH deficiency (GHD) and the baseline characteristics of the patients including biochemical and psychometric parameters. Using an update of the KIMS pharmaco-epidemiological database (Pfizer International Metabolic Database), we addressed the question h...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-09-0273

    authors: Brabant G,Poll EM,Jönsson P,Polydorou D,Kreitschmann-Andermahr I

    更新日期:2009-11-01 00:00:00

  • The impact of chronic in vivo glucocorticoid excess on the functional characteristics of human skin fibroblasts obtained from patients with endogenous Cushing's syndrome.

    abstract:OBJECTIVE:Chronic exposure to elevated glucocorticoid (GC) concentrations induces detrimental effects in several tissues. In the skin, GCs provoke intense alterations on various parameters of the physiology of fibroblasts, cumulatively leading to skin atrophy and impaired wound healing. As there are concerns that GCs m...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.1.01913

    authors: Zervolea I,Pratsinis H,Tsagarakis S,Karavitaki N,Stathakos D,Thalassinos N,Kletsas D

    更新日期:2005-06-01 00:00:00

  • Diagnostic and prognostic value of immunocytochemistry and BRAF mutation analysis on liquid-based biopsies of thyroid neoplasms suspicious for carcinoma.

    abstract:OBJECTIVE:In the field of fine-needle aspiration cytology, the category of suspicious for malignancy (SM) thyroid lesions, that bears 55-85% risk of malignant histology, is a challenging topic in which morphology alone is not always able to make a correct diagnosis. Recently, immunocytochemistry (ICC) has been referred...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-13-0023

    authors: Rossi ED,Martini M,Capodimonti S,Straccia P,Cenci T,Lombardi CP,Pontecorvi A,Larocca LM,Fadda G

    更新日期:2013-05-02 00:00:00

  • Anionic iodotyrosine residues are required for iodothyronine synthesis.

    abstract::Biosynthesis of iodothyronines in thyroglobulin occurs by oxidative coupling of two iodotyrosine residues catalyzed by thyroperoxidase. To study the mechanism of iodothyronine formation, iodine-free thyroglobulin was non-enzymatically iodinated and after removal of non-incorporated iodide, incubated with lactoperoxida...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.0.1380227

    authors: de Vijlder JJ,den Hartog MT

    更新日期:1998-02-01 00:00:00

  • Affective alterations in patients with Cushing's syndrome in remission are associated with decreased BDNF and cortisone levels.

    abstract:OBJECTIVE:Affective alterations and poorer quality of life often persist in patients with Cushing's syndrome (CS) in remission. Brain-derived neurotrophic factor (BDNF) regulates the hypothalamic-pituitary-adrenal axis (HPA) and is highly expressed in brain areas controlling mood and response to stress. Our aims were t...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-16-0779

    authors: Valassi E,Crespo I,Keevil BG,Aulinas A,Urgell E,Santos A,Trainer PJ,Webb SM

    更新日期:2017-02-01 00:00:00

  • Genetic variation in receptor protein tyrosine phosphatase sigma is associated with type 2 diabetes in Swedish Caucasians.

    abstract:OBJECTIVE:Previously, it has been demonstrated that receptor protein tyrosine phosphatase sigma (RPTPsigma) is involved in glucose homeostasis and insulin signaling in several animal models. The aim of this study was to evaluate whether polymorphisms in this gene influence the development of type 2 diabetes (T2D) in hu...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-07-0114

    authors: Långberg EC,Gu HF,Nordman S,Efendic S,Ostenson CG

    更新日期:2007-10-01 00:00:00

  • Regulation of neuropeptide Y mRNA expression in cultured human pheochromocytoma cells.

    abstract::The expression of the neuropeptide Y (NPY) gene varies considerably in human pheochromocytomas, but the mechanisms for this variation have not been clarified. To investigate the regulation pattern of the NPY gene in human pheochromocytomas, we screened 16 pheochromocytomas and 9 normal adrenal tissues with Northern bl...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.0.1410431

    authors: Liu J,Kahri AI,Heikkilä P,Voutilainen R

    更新日期:1999-10-01 00:00:00

  • Increased leptin, decreased adiponectin and FGF21 concentrations in adolescent offspring of women with gestational diabetes.

    abstract:Objective:Fetal exposure to gestational diabetes mellitus (GDM) increases the risk of metabolic diseases in the offspring. Leptin, adiponectin, and fibroblast growth factor 21 (FGF21) may play potential roles in the underlying disease mechanisms. We investigated the impact of fetal exposure to GDM on leptin, adiponecti...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-19-0658

    authors: Kampmann FB,Thuesen ACB,Hjort L,Bjerregaard AA,Chavarro JE,Frystyk J,Bjerre M,Tetens I,Olsen SF,Vaag AA,Damm P,Grunnet LG

    更新日期:2019-12-01 00:00:00

  • Amiodarone compared with iodine exhibits a potent and persistent inhibitory effect on TSH-stimulated cAMP production in vitro: a possible mechanism to explain amiodarone-induced hypothyroidism.

    abstract::Amiodarone (AMD) is a powerful anti-arrhythmic drug used for the treatment of a wide variety of cardiac arrhythmias and its most striking feature is its high iodine content. Thyroid dysfunction is a limiting side-effect of the drug and both AMD-induced hypothyroidism (AIH) and AMD-induced thyrotoxicosis (AIT) are repo...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.0.1400241

    authors: Pitsiavas V,Smerdely P,Boyages SC

    更新日期:1999-03-01 00:00:00

  • Gamma knife radiosurgery is a successful adjunctive treatment in Cushing's disease.

    abstract:OBJECTIVE:Though transsphenoidal surgery remains the first-line treatment of Cushing's disease, recurrence occurs frequently. Conventional radiotherapy and anticortisolic drugs both have adverse effects. Stereotactic radiosurgery needs to be evaluated more precisely. The aim of this study was to determine long-term hor...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.1.02323

    authors: Castinetti F,Nagai M,Dufour H,Kuhn JM,Morange I,Jaquet P,Conte-Devolx B,Regis J,Brue T

    更新日期:2007-01-01 00:00:00

  • Birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults.

    abstract:OBJECTIVE:To investigate the association between birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults. RESEARCH METHODS AND PROCEDURES:Nine hundred and seventy-three individuals from a population-based cross-sectional survey for the prevalence of type 2 diabetes conducted i...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.1.02265

    authors: Tian JY,Cheng Q,Song XM,Li G,Jiang GX,Gu YY,Luo M

    更新日期:2006-10-01 00:00:00

  • Minimal impact of excess iodate intake on thyroid hormones and selenium status in older New Zealanders.

    abstract:OBJECTIVE:Iodine deficiency has re-emerged in New Zealand, while selenium status has improved. The aim of this study was to investigate the effects of excess iodine intake as iodate on thyroid and selenium status. METHODS:In a randomized controlled trial on older people (mean±s.d. 73±4.8 years; n=143), two groups rece...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,随机对照试验

    doi:10.1530/EJE-11-0575

    authors: Thomson CD,Campbell JM,Miller J,Skeaff SA

    更新日期:2011-11-01 00:00:00

  • Downregulation of long-form prolactin receptor mRNA during prolactin-induced luteal regression.

    abstract:OBJECTIVE:Prolactin is capable of both trophic and lytic actions in rat corpora lutea. In corpora lutea responding to a trophic prolactin signal, the long form of the prolactin receptor is the dominant form and is upregulated by prolactin. We investigated whether mRNA for the short form of the prolactin receptor was do...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.0.1430285

    authors: Bowen JM,Telleria CM,Towns R,Keyes PL

    更新日期:2000-08-01 00:00:00

  • Iodine fortification may influence the age-related change in thyroid volume: a longitudinal population-based study (DanThyr).

    abstract:OBJECTIVE:To assess the individuals' thyroid volume changes after the mandatory nationwide iodine fortification (IF) program in two Danish areas with different iodine intake at baseline (Copenhagen, mild iodine deficiency (ID) and Aalborg, moderate ID). DESIGN:A longitudinal population-based study (DanThyr). METHODS:...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-13-0918

    authors: Krejbjerg A,Bjergved L,Pedersen IB,Carlé A,Jørgensen T,Perrild H,Ovesen L,Rasmussen LB,Knudsen N,Laurberg P

    更新日期:2014-03-08 00:00:00

  • MANAGEMENT OF ENDOCRINE DISEASE: Diagnostic and therapeutic approach of tall stature.

    abstract::Tall stature is defined as a height of more than 2 standard deviations (s.d.) above average for same sex and age. Tall individuals are usually referred to endocrinologists so that hormonal disorders leading to abnormal growth are excluded. However, the majority of these patients have familial tall stature or constitut...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1530/EJE-16-1054

    authors: Albuquerque EVA,Scalco RC,Jorge AAL

    更新日期:2017-06-01 00:00:00

  • Relationship of serum fibroblast growth factor 23 with cardiovascular disease in older community-dwelling women.

    abstract:OBJECTIVE:Although fibroblast growth factor 23 (FGF23) has been implicated in the pathogenesis of cardiovascular disease, the relationship between FGF23 and cardiovascular disease has not been well characterized in the general population. The aim of this study was to determine whether serum FGF23 is independently assoc...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,随机对照试验

    doi:10.1530/EJE-11-0577

    authors: Dalal M,Sun K,Cappola AR,Ferrucci L,Crasto C,Fried LP,Semba RD

    更新日期:2011-11-01 00:00:00

  • Pegvisomant and Pasireotide LAR as second line therapy in acromegaly: clinical effectiveness and predictors of response.

    abstract:Background:The treatment of acromegaly resistant to first-generation somatostatin receptor ligands (SRLs) is often difficult. Pegvisomant and Pasireotide LAR are mostly used in these subset of patients, as second line therapies. Choice of the type of second line therapies is difficult, since predictors of response are ...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-20-0767

    authors: Chiloiro S,Giampietro A,Mirra F,Donfrancesco F,Tartaglione T,Mattogno PP,Angelini F,Liverana L,Gessi M,Carmelo A,Rindi G,Giustina A,Fleseriu M,Pontecorvi A,De Marinis L,Bianchi A

    更新日期:2021-02-01 00:00:00

  • Dexamethasone impairs insulin signalling and glucose transport by depletion of insulin receptor substrate-1, phosphatidylinositol 3-kinase and protein kinase B in primary cultured rat adipocytes.

    abstract:OBJECTIVE:Glucocorticoid excess leads to insulin resistance. This study explores the effects of glucocorticoids on the glucose transport system and insulin signalling in rat adipocytes. The interaction between glucocorticoids and high levels of insulin and glucose is also addressed. DESIGN AND METHODS:Isolated rat adi...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.0.1460419

    authors: Burén J,Liu HX,Jensen J,Eriksson JW

    更新日期:2002-03-01 00:00:00

  • Identification of a deletion variant in the gene encoding the human alpha(2A)-adrenergic receptor.

    abstract:OBJECTIVE:The alpha(2)-adrenergic receptors are involved in the effects of catecholamines on energy metabolism. Of three known subtypes with differential expression, alpha(2A)-adrenergic receptors are also localized in adipose tissue where they counteract the lipolytic activity of beta-adrenergic receptors. This study ...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/eje.0.1440291

    authors: Hamann A,Brieske C,Tafel J,Buttron P,Schwarzloh B,Münzberg H,Hinney A,Mayer H,Siegfried W,Hebebrand J,Greten H,Algenstaedt P,Ziegler R

    更新日期:2001-03-01 00:00:00

  • Osteogenesis imperfecta: an update on clinical features and therapies.

    abstract::Osteogenesis imperfecta (OI) is an inherited skeletal dysplasia characterized by bone fragility and skeletal deformities. While the majority of cases are associated with pathogenic variants in COL1A1 and COL1A2, the genes encoding type I collagen, up to 25% of cases are associated with other genes that function within...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,评审

    doi:10.1530/EJE-20-0299

    authors: Marom R,Rabenhorst BM,Morello R

    更新日期:2020-10-01 00:00:00

  • Impaired quality of life and sexual function in overweight and obese men: the European Male Ageing Study.

    abstract:BACKGROUND:Few published data link overweight and obesity with measures of quality of life (QoL) including sexual health in men. OBJECTIVE:To assess the association of overweight/obesity with impairment of physical and psychological QoL and sexual functions in men. DESIGN AND SETTING:Cross-sectional, multicentre surv...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章

    doi:10.1530/EJE-10-1129

    authors: Han TS,Tajar A,O'Neill TW,Jiang M,Bartfai G,Boonen S,Casanueva F,Finn JD,Forti G,Giwercman A,Huhtaniemi IT,Kula K,Pendleton N,Punab M,Silman AJ,Vanderschueren D,Lean ME,Wu FC,EMAS group.

    更新日期:2011-06-01 00:00:00