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The survival and value of liver transplantation for liver carcinoma: a single-center experience.

Abstract：

UNLABELLED:Liver transplantation for liver carcinoma with cirrhosis is a treatment still in dispute. The objectives were to summarize the survival and cost of 50 liver transplant cases performed for liver carcinoma over nearly 3 years. METHODS:We performed 138 liver transplants from January 1999 to February 2002. There were 50 cases (36.2%) of liver carcinoma with HBV cirrhosis, which were divided into three stages based on the tumor pathology: Stage 1 cases showed a single mass (< or = 5 cm), 4 cases; Stage 2, a single mass > 5 cm or intrahepatic multiple masses without PV cancer embolus, 32 cases; and Stage 3: tumor invasion of the PV or perihepatic lymph nodes or organs, 14 cases. All patients received three to six courses of chemotherapy postoperatively. RESULTS:All four cases of stage 1 survived > 1 year; one of them is at 3 years with good liver function and tumor free. The mean half-year medical cost was $27.100 +/- 108 in stage 1. The half-year survival and medical costs were 62.5% and $31,500 +/- 260 in stage 2 and 15.0% and $35,500 +/- 134 in stage 3. CONCLUSION:Liver transplantation is an effective treatment for early-stage liver carcinoma, that achieves good medical and economic results, but should be limited to advanced liver cancer.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Chen ZS,Zeng FJ,Ming CS,Lin ZB,Zhang WJ,Wei L,Zhu XH,Jiang JP,Chen ZK

doi

10.1016/j.transproceed.2004.08.047

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

2284-6

issue

8

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(04)00917-0

journal_volume

36

pub_type

杂志文章

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