Abstract:
:Mild to moderate hypertension is usually asymptomatic and therefore the impact on quality of life and side-effects of the antihypertensive treatment can have a negative effect on treatment compliance. A number of comparative studies have addressed quality of life issues with various antihypertensive agents, and the results of these studies are summarised in this article with particular reference to ACE inhibitors.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Os Isubject
Has Abstractpub_date
1994-09-01 00:00:00pages
S27-30eissn
0950-9240issn
1476-5527journal_volume
8 Suppl 1pub_type
杂志文章abstract::Syst. China Trial aimed to determine whether titrated antihypertensive treatment could reduce the risk of stroke incidence and other cardiovascular complications among 2,298 older Chinese patients (> or = 60) with isolated systolic hypertension. The data from 3 years follow-up showed that the blood pressure reduction ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:1996-02-01 00:00:00
abstract::Sudden death has been shown to be due in the majority of cases to ventricular arrhythmia. Left ventricular hypertrophy (LVH) may be implicated in the aetiology of some arrhythmia and sudden death. Recent evidence suggests that the relationship between LVH and arrhythmia may be complex and that there may be an interact...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::An association of obesity and hypertension is well recognised and there is a direct positive relationship between body weight or body mass index (BMI) and blood pressure (BP), although the mechanisms responsible for weight-related increases of BP are still unknown. Obesity does appear to be an independent risk factor ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Hypertension prevalence rates remain comparatively low in Nigeria, although the associated morbidity and mortality including that due to malignant hypertension (MHT) is considerable. To determine the factors that may be associated with the development of MHT we compared 74 patients with essential MHT (age 48 +/- 9 yea...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1000963
更新日期:2000-03-01 00:00:00
abstract::Cardiovascular risk is subject to circadian variation, with peak morning incidence of myocardial infarction and stroke correlating with the early morning blood pressure (BP) surge (EMBPS). Ideally, antihypertensive therapy should maintain control of BP throughout the 24-h dosing cycle. In two sister studies, Prospecti...
journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
doi:10.1038/jhh.2009.4
更新日期:2009-09-01 00:00:00
abstract::The study evaluated the extent to which high normal blood pressure (HNBP), elevated BP, and Stage 1 hypertension predict 10-year incidence of cardiovascular disease (CVD). A population-based, prospective cohort study was conducted among 3042 randomly selected Greek adults, aged 18-89 years. Following 10-years follow-u...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-019-0169-z
更新日期:2019-04-01 00:00:00
abstract::High leptin levels are often observed in human obesity and are implicated in obesity-related hypertension. Leptin levels have been found to be higher in hypertensive obese African-American women compared to normotensive African-American women, but a direct association between leptin and blood pressure could not be obt...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001856
更新日期:2005-07-01 00:00:00
abstract::Hypertension is a known risk factor in the genesis of coronary artery disease. However, the effect of pre-existing hypertension on the long-term mortality in patients with established coronary heart disease is not clear. The present cohort study analysed the influence of baseline mild to moderate treated hypertension ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract::Non-modulating is a highly reproducible type of sodium-sensitive hypertension. The aim of this study was to evaluate in non-modulating individuals the erythrocyte sodium-lithium countertransport (SLC) abnormalities, which have been mentioned as a marker of non-modulation, and the association with increased microalbumi...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001358
更新日期:2002-03-01 00:00:00
abstract::We have investigated 59 patients with mild-to-moderate uncomplicated essential hypertension in order to estimate whether salt sensitivity is associated with greater urinary albumin excretion. Patients whose average mean blood pressure (BP) value on day 5 of the high-sodium regimen (300 mmol/l NaCl) exceeded 10 mm Hg o...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::This study aimed to test the role of family social support, depression, anxiety and self-efficacy on specific self-care behaviours. In a local community health center, 318 patients with hypertension completed a questionnaire assessing self-care, family social support, depression, anxiety and self-efficacy in 2012. Eac...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2014.58
更新日期:2015-03-01 00:00:00
abstract::The reasons why women and men are treated with different antihypertensive drugs are not clear. Whether socioeconomic factors influence prescription patterns and blood pressure control differently in women and men has not been investigated. This cross-sectional study performed in a cohort of hypertensive patients from ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2014.100
更新日期:2015-06-01 00:00:00
abstract::To evaluate the correlation between endothelial dysfunction and multiple target organ damage (TOD), we measured endothelial function using high-resolution ultrasonography in hypertensive patients with or without TOD. Two hundred and eighty patients with hypertension were divided into four groups as follows: no TOD (Gr...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2009.10
更新日期:2009-11-01 00:00:00
abstract::A large proportion of hypertensive men and women in Europe and North America are overweight. In obesity, the expanded blood volume increases cardiopulmonary volume, cardiac filling, left ventricular preload, stroke volume and, thereby, left ventricular work. Given enough exposure time, it is probable that all obese pe...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:
更新日期:1990-08-01 00:00:00
abstract::This study recruited 85 healthy children and adolescents, aged 6-18 years, from a school-based blood pressure (BP) screening study and performed office BP measurements, 24-h ambulatory blood pressure monitoring (24-h ABPM) and 24-h pulse wave analysis. Prevalence of BP phenotypes was assessed, factors that may predict...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-020-0318-4
更新日期:2021-01-01 00:00:00
abstract::The prognostic value of ambulatory blood pressure (BP) monitoring for long-term prognosis varies in recent studies. The study aimed to investigate the role of ambulatory BP parameters in mortality and cardiovascular (CV) events in hypertensive patients. A series of 412 participants (59.3 ± 4.0 years) who received ambu...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2010.80
更新日期:2011-07-01 00:00:00
abstract::We tested the utility of qualitative microalbuminuria (MAU) screening in an office practice setting, in assessing the response of MAU to drug treatment. We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and routine laboratory values as clinically indicated on > 6000 n...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::Hypertension is strongly influenced by genetic factors. Although hypertension prevalence in some Hispanic sub-populations is greater than in non-Hispanic whites, genetic studies on hypertension have focused primarily on samples of European descent. A recent meta-analysis of 200 000 individuals of European descent iden...
journal_title:Journal of human hypertension
pub_type: 杂志文章,meta分析,多中心研究
doi:10.1038/jhh.2016.29
更新日期:2016-12-01 00:00:00
abstract::Results of an analysis of the cost-effectiveness of hypertension treatment in Sweden are presented. The cost per life-year gained decreases with age for both men and women and is relatively low for middle-aged and older men and women even in the blood pressure range 90-94 mmHg. The results indicate that it is in gener...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract::Haemorrhagic diathesis develops in chronic renal failure, in which calcium antagonists are used widely as antihypertensive agents. Although calcium antagonists are reported to impair platelet function, it has not been examined whether calcium antagonists alter bleeding time. The present study was conducted to clarify ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.jhh.1001327
更新日期:2002-03-01 00:00:00
abstract::Erythrocyte Na/K flux ratio was examined in relation to a family history of essential hypertension (FH-HT) and plasma and urine electrolytes in 84 normotensive children (13-15 yrs old), and in relation to sodium intake in six children with acute glomerulonephritis or IgA nephropathy who had normal renal function (6-13...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::This study evaluated insulin secretion and insulin sensitivity before and after short-term oral administration of doxazosin in patients with essential hypertension. The hypertensive group consisted of 11 nonobese subjects (aged 41.0 +/- 2.5 years (mean +/- SEM), body mass index 24.0 +/- 0.53 kg/m2). The normotensive g...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
abstract::Riley Day syndrome, commonly referred to as familial dysautonomia (FD), is a genetic disease with extremely labile blood pressure owing to baroreflex deafferenation. Chronic renal disease is very frequent in these patients and was attributed to recurrent arterial hypotension and renal hypoperfusion. Aggressive treatme...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2011.107
更新日期:2013-01-01 00:00:00
abstract::We have investigated the use of captopril as a screening test for renovascular hypertension and compared the effects of captopril on renal function in patients with renovascular hypertension and those without renovascular hypertension. The captopril test and kidney gamma scintigraphy were carried out in 50 hypertensiv...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract::High dietary salt is a major contributor to increased blood pressure, the leading risk for death worldwide. In several countries, national programmes to reduce dietary salt have been implemented with leadership and involvement of hypertension experts. Other hypertension experts may be interested in assisting or leadin...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/jhh.2011.25
更新日期:2011-12-01 00:00:00
abstract::Resistant hypertension (RHTN) includes both patients whose blood pressure (BP) is uncontrolled on three or more medications (uncontrolled RHTN (UCRH)) and patients whose BP is controlled with use of four or more drugs (controlled RHTN (CRH)). It is unknown whether endothelial function and nocturnal drop demonstrate a ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2011.43
更新日期:2011-11-01 00:00:00
abstract::To assess the suitability of therapy with an angiotensin-converting enzyme inhibitor for older hypertensives, a randomised double blind two group comparison of enalapril (10 to 40 mg daily) with hydrochlorothiazide (25 to 100 mg daily) was carried out in 32 untreated and independently living subjects aged 63 to 82 yea...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-04-01 00:00:00
abstract::Determining blood pressure (BP) values at different daily time periods is a well recognised measure to assess the risk of end-organ damage. However, the use of various definitions of these periods, eg, day vs night, sleep vs wake or arbitrary definitions, makes clinical decisions based on available data difficult. In ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1000910
更新日期:1999-11-01 00:00:00
abstract::In phaeochromocytoma, sudden hypertensive or arrhythmic episodes are believed to be associated with excessive free catecholamine excretion. However, lack of correlation between blood pressure (BP) and plasma catecholamine levels has been reported. Therefore an attempt was made to assess the sympathovagal balance befor...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The C(-344)T promoter polymorphism of the human aldosterone synthase (CYP11B2) gene has been associated with hypertension and cardiac hypertrophy, but there were contrasting data. We analysed the genotype/phenotype associations between this polymorphism and cardiovascular variables in a young adult population, where i...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001619
更新日期:2003-12-01 00:00:00