Abstract：
:An adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations. The test statistic is a direct statistical analogue of the popular "funnel-graph." The number of component studies in the meta-analysis, the nature of the selection mechanism, the range of variances of the effect size estimates, and the true underlying effect size are all observed to be influential in determining the power of the test. The test is fairly powerful for large meta-analyses with 75 component studies, but has only moderate power for meta-analyses with 25 component studies. However, in many of the configurations in which there is low power, there is also relatively little bias in the summary effect size estimate. Nonetheless, the test must be interpreted with caution in small meta-analyses. In particular, bias cannot be ruled out if the test is not significant. The proposed technique has potential utility as an exploratory tool for meta-analysts, as a formal procedure to complement the funnel-graph.
journal_name
Biometricsjournal_title
Biometricsauthors
Begg CB,Mazumdar Msubject
Has Abstractpub_date
1994-12-01 00:00:00pages
1088-101issue
4eissn
0006-341Xissn
1541-0420journal_volume
50pub_type
杂志文章相关文献
BIOMETRICS文献大全abstract：:Tag loss in mark-recapture experiments is a violation of one of the Jolly-Seber model assumptions. It causes bias in parameter estimates and has only been dealt with in an ad hoc manner. We develop methodology to estimate tag retention and abundance in double-tagging mark-recapture experiments. We apply this methodolo...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.1541-0420.2006.00523.x
更新日期：2006-09-01 00:00:00
abstract：:A method is presented for choosing an additive constant c when transforming data x to y = log(x + c). The method preserves Type I error probability and power in ANOVA under the assumption that the x + c for some c are log-normally distributed. The method has advantages similar to those of rank transformations--namely,...
journal_title：Biometrics
pub_type： 临床试验,杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：:A new test using incidence data is developed for testing whether two or more groups have the same seasonal pattern. The method fits sine waves to the data with a fundamental period of one cycle per year, and has the possibility of using higher harmonics, when necessary, to adequately model the data. The seasonal patte...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：:In genetic family studies, ages at onset of diseases are routinely collected. Often one is interested in assessing the familial association of ages at the onset of a certain disease type. However, when a competing risk is present and is related to the disease of interest, the usual measure of association by treating t...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.1541-0420.2009.01372.x
更新日期：2010-12-01 00:00:00
abstract：:We consider methods for estimating the treatment effect and/or the covariate by treatment interaction effect in a randomized clinical trial under noncompliance with time-to-event outcome. As in Cuzick et al. (2007), assuming that the patient population consists of three (possibly latent) subgroups based on treatment p...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/biom.12472
更新日期：2016-09-01 00:00:00
abstract：:Adaptive line transect sampling offers the potential of improved population density estimation efficiency over conventional line transect sampling when populations are spatially clustered. In adaptive sampling, survey effort is increased when areas of high animal density are located, thereby increasing the number of o...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.0006-341x.2002.00862.x
更新日期：2002-12-01 00:00:00
abstract：:We consider a capture-recapture model in which capture probabilities vary with time and with behavioral response. Two inference procedures are developed under the assumption that recapture probabilities bear a constant relationship to initial capture probabilities. These two procedures are the maximum likelihood metho...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.0006-341x.2000.00427.x
更新日期：2000-06-01 00:00:00
abstract：:To evaluate diagnostic tests, one would ideally like to verify, for example, with a biopsy, the disease state of all subjects in a study. Often, however, no all subjects are verified. Previous methods for evaluation assume that the decision to verify depends only on recorded variables. Sometimes, particularly if the d...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:We consider modeling correlated survival data when cluster sizes may be informative to the outcome of interest based on a within-cluster resampling (WCR) approach and a weighted score function (WSF) method. We derive the large sample properties for the WCR estimators under the Cox proportional hazards model. We establ...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.1541-0420.2006.00730.x
更新日期：2007-09-01 00:00:00
abstract：:Estimating the number of clusters in a data set is a crucial step in cluster analysis. In this article, motivated by the gap method (Tibshirani, Walther, and Hastie, 2001, Journal of the Royal Statistical Society B63, 411-423), we propose the weighted gap and the difference of difference-weighted (DD-weighted) gap met...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.1541-0420.2007.00784.x
更新日期：2007-12-01 00:00:00
abstract：:In this paper, a Markov process is developed as a mathematical model to study the general problem of quality control monitoring. This approach was previously used by Arnold (1970) in development of sampling plans to study the water quality monitoring of streams. Arnold considered the expected sample size required for ...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1977-03-01 00:00:00
abstract：:A general theory for estimating the size of a closed population from multiple-recapture data is presented. This theory is easily extended to open population models for multiple-recapture data. Estimation is based on a log-linear model developed for modeling dependent capture-recapture data when capture probabilities v...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:With the prevalence of gene expression studies and the relatively low reproducibility caused by insufficient sample sizes, it is natural to consider joint analysis that could combine data from different experiments effectively to achieve improved accuracy. We present in this article a model-based approach for better i...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.1541-0420.2011.01602.x
更新日期：2011-12-01 00:00:00
abstract：:Mixed longitudinal growth data consists of several observations on a characteristic over a limited age range for each individual in a study. This data is then combined to model growth over the total age range of all individuals in the study. The limited data collected on each individual precludes a subject-specific ap...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：:Identifying factors associated with increased medical cost is important for many micro- and macro-institutions, including the national economy and public health, insurers and the insured. However, assembling comprehensive national databases that include both the cost and individual-level predictors can prove challengi...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/biom.12464
更新日期：2016-09-01 00:00:00
abstract：:An important objective in biomedical and environmental risk assessment is estimation of minimum exposure levels that induce a pre-specified adverse response in a target population. The exposure points in such settings are typically referred to as benchmark doses (BMDs). Parametric Bayesian estimation for finding BMDs ...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/biom.12340
更新日期：2015-12-01 00:00:00
abstract：:In this article, we present an estimation approach for solving nonlinear constrained generalized estimating equations that can be implemented using object-oriented software for nonlinear programming, such as nlminb in Splus or fmincon and lsqnonlin in Matlab. We show how standard estimating equation theory includes th...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.0006-341x.2000.01268.x
更新日期：2000-12-01 00:00:00
abstract：:Analysis of longitudinal studies is often complicated through differences amongst individuals in the number and spacing of observations. Laird and Ware (1982, Biometrics 38, 963-974) proposed a linear random-effects model to deal with this problem. We propose a generalisation of this model to accommodate multiple rand...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Three properties of interest in bioavailability studies using compartmental models are the area under the concentration curve, the maximum concentration, and the time to maximum concentration. Methods are described for finding designs that minimize the variance of the estimates of these quantities in such a model. The...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:The estimation of maternal genetic variances by a multivariate maximum likelihood method is discussed. As an illustration the method is applied to data on Tribolium using a model based on partitioning the maternal genetic effect into additive and dominance components. An alternative model due to Falconer (1965) is als...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1976-12-01 00:00:00
abstract：:In a study designed to assess the relationship between a dichotomous exposure and the eventual occurrence of a dichotomous outcome, frequency matching has been proposed as a way to balance the exposure cohorts with respect to the sampling distribution of potential confounding factors. This paper discusses the pooled e...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:In an epidemiological study of risk factors in breast cancer, data are available on confirmed cases from a diagnostic clinic and on controls from a screening clinic that sampled the general population. Relative risk estimation is complicated by differences in the interviewing environment and in the wording and order o...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1983-09-01 00:00:00
abstract：:Recurrent events data are commonly encountered in medical studies. In many applications, only the number of events during the follow-up period rather than the recurrent event times is available. Two important challenges arise in such studies: (a) a substantial portion of subjects may not experience the event, and (b) ...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/biom.13085
更新日期：2019-12-01 00:00:00
abstract：:In many medical experiments, data are collected across time, over a number of similar trials, or over a number of experimental units. As is the case of neuron spike train studies, these data may be in the form of counts of events per unit of time. These counts may be correlated within each trial. It is often of intere...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:This paper describes methodology for analyzing data from cluster randomized trials with count outcomes, taking indirect effects as well spatial effects into account. Indirect effects are modeled using a novel application of a measure of depth within the intervention arm. Both direct and indirect effects can be estimat...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/biom.13316
更新日期：2020-06-18 00:00:00
abstract：:The class of admissible tests for Hardy-Weinberg equilibrium in a multi-allelic system is characterized. The standard goodness-of-fit chi-square tests is shown to be admissible for systems of two or more alleles. The conditional probability distribution required to determine the exact significance level of this test i...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：:Given data from bilateral visual assessments on N subjects at k occasions, we consider inference for contralateral correlations (C) between fellow eyes and lateral correlations (L) among p different assessments of the same eye. Under permutation symmetric dependence structure between observations from fellow eyes and ...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.0006-341x.2000.01188.x
更新日期：2000-12-01 00:00:00
abstract：:This paper establishes a framework for understanding the complex relationships between HIV-1 genotypic markers of resistance to antiretroviral drugs and clinical measures of disease progression. A new classification scheme based on the probabilities of how new patients will respond to antiretroviral therapy given the ...
journal_title：Biometrics
pub_type： 杂志文章
doi：10.1111/j.0006-341x.2002.00145.x
更新日期：2002-03-01 00:00:00
abstract：:The risks of conception, due to sexual intercourse at various times before and after the periovulatory rise in the woman's basal body temperature, are evaluated. In general, the risk is small nine or more days before, and two or more days after, the first day of elevated temperature. The model for the conception proba...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1982-06-01 00:00:00
abstract：:Brownie, Boos, and Hughes-Oliver (1990, Biometrics 46, 259-266) suggested a modification to the fixed-effects analysis of variance (ANOVA) F test for use in situations where treatments are likely to affect mean response while simultaneously increasing between-subject variability. These authors suggest that the modifie...
journal_title：Biometrics
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
