Abstract:
:A new test using incidence data is developed for testing whether two or more groups have the same seasonal pattern. The method fits sine waves to the data with a fundamental period of one cycle per year, and has the possibility of using higher harmonics, when necessary, to adequately model the data. The seasonal pattern can, therefore, have an arbitrary shape. The method allows for different length time intervals and different size populations at risk in the time intervals. Maximum likelihood estimation, based on the Poisson distribution, is used to determine the parameters of the model. Likelihood ratio tests and Akaike's information criterion (AIC) are used to determine the number of harmonics, and to test hypotheses. This method has been used to test for seasonal patterns in the incidence of insulin-dependent diabetes mellitus (IDDM) in Colorado among persons aged 0-17 years. Comparisons of seasonal patterns are made between males and females, and three age groups, each controlling for the other effect as in analysis of variance. Other potential applications of this approach are also discussed. A basic program is available for an IBM-PC to carry out these analyses.
journal_name
Biometricsjournal_title
Biometricsauthors
Jones RH,Ford PM,Hamman RFsubject
Has Abstractpub_date
1988-12-01 00:00:00pages
1131-44issue
4eissn
0006-341Xissn
1541-0420journal_volume
44pub_type
杂志文章相关文献
BIOMETRICS文献大全abstract::Stepped wedge designed trials are a type of cluster-randomized study in which the intervention is introduced to each cluster in a random order over time. This design is often used to assess the effect of a new intervention as it is rolled out across a series of clinics or communities. Based on a permutation argument, ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13106
更新日期:2020-03-01 00:00:00
abstract::In this article, we propose a new statistical method-MutRSeq-for detecting differentially expressed single nucleotide variants (SNVs) based on RNA-seq data. Specifically, we focus on nonsynonymous mutations and employ a hierarchical likelihood approach to jointly model observed mutation events as well as read count me...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12548
更新日期:2017-03-01 00:00:00
abstract::In this article, we describe a Bayesian approach to the calibration of a stochastic computer model of chemical kinetics. As with many applications in the biological sciences, the data available to calibrate the model come from different sources. Furthermore, these data appear to provide somewhat conflicting informatio...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2009.01245.x
更新日期:2010-03-01 00:00:00
abstract::Consider a collection of spatially clustered objects where the clusters are geographically rare. Of interest is estimation of the total number of objects on the site from a sample of plots of equal size. Under these spatial conditions, adaptive cluster sampling of plots is generally useful in improving efficiency in e...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2000.00503.x
更新日期:2000-06-01 00:00:00
abstract::Given a large number of t-statistics, we consider the problem of approximating the distribution of noncentrality parameters (NCPs) by a continuous density. This problem is closely related to the control of false discovery rates (FDR) in massive hypothesis testing applications, e.g., microarray gene expression analysis...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2012.01764.x
更新日期:2012-12-01 00:00:00
abstract::Logistic regression is a popular tool for risk analysis in medical and population health science. With continuous response data, it is common to create a dichotomous outcome for logistic regression analysis by specifying a threshold for positivity. Fitting a linear regression to the nondichotomized response variable a...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12007
更新日期:2013-06-01 00:00:00
abstract::A life table estimates probabilities of surviving and of dying as well as death rates, as these would apply in a stationary population with the same underlying continuous mortality curve as the observed population. We have derived approximations to the probability of surviving that require no iteration, do not depend ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1975-12-01 00:00:00
abstract::In epidemiologic studies of time to an event, mean lifetime is often of direct interest. We propose methods to estimate group- (e.g., treatment-) specific differences in restricted mean lifetime for studies where treatment is not randomized and lifetimes are subject to both dependent and independent censoring. The pro...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2010.01503.x
更新日期:2011-09-01 00:00:00
abstract::Large amounts of longitudinal health records are now available for dynamic monitoring of the underlying processes governing the observations. However, the health status progression across time is not typically observed directly: records are observed only when a subject interacts with the system, yielding irregular and...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13261
更新日期:2020-03-11 00:00:00
abstract::In many longitudinal clinical studies, the level and progression rate of repeatedly measured biomarkers on each subject quantify the severity of the disease and that subject's susceptibility to progression of the disease. It is of scientific and clinical interest to relate such quantities to a later time-to-event clin...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2008.01168.x
更新日期:2009-09-01 00:00:00
abstract::This article demonstrates semiparametric maximum likelihood estimation of a nonlinear growth model for fish lengths using imprecisely measured ages. Data on the species corvina reina, found in the Gulf of Nicoya, Costa Rica, consist of lengths and imprecise ages for 168 fish and precise ages for a subset of 16 fish. T...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2002.00448.x
更新日期:2002-06-01 00:00:00
abstract::Interference occurs when the treatment of one person affects the outcome of another. For example, in infectious diseases, whether one individual is vaccinated may affect whether another individual becomes infected or develops disease. Quantifying such indirect (or spillover) effects of vaccination could have important...
journal_title:Biometrics
pub_type: 杂志文章,随机对照试验
doi:10.1111/biom.12184
更新日期:2014-09-01 00:00:00
abstract:SUMMARY:A trend test is often employed to analyze ordered categorical data, in which a set of increasing scores is assigned a priori. There is a drawback in this approach, because how to choose a set of scores is not clear. There have been debates on which scores should be used (e.g., Graubard and Korn, 1987, Biometric...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2008.00992.x
更新日期:2008-12-01 00:00:00
abstract::The paper here presented was motivated by a case study involving high-dimensional and high-frequency tidal volume traces measured during induced panic attacks. The focus was to develop a procedure to determine the significance of whether a mean curve dominates another one. The key idea of the suggested method relies o...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2007.00959.x
更新日期:2008-09-01 00:00:00
abstract::Jolliffe and Jolliffe (1997, Biometrics 53, 1136-1142) proposed various models for data from an experiment on memory in coal tits. This article describes an alternative model, which fits equally well and which may be simpler to interpret. ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.1999.00660.x
更新日期:1999-06-01 00:00:00
abstract::A full-likelihood procedure is proposed for analyzing correlated binary data under the assumption of exchangeability. The binomial and beta-binomial models are shown to occur as special cases correspondingly, respectively, to the choice of degenerate and beta-mixing distributions. For a finite exchangeable binary sequ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::Consider two independent random variables X and Y. The functional R = Pr(X less than Y) [or gamma = Pr(X less than Y) - Pr(Y less than X)] is of practical importance in many situations, including clinical trials, genetics, and reliability. In this paper several approaches to estimation of gamma when X and Y are presen...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1986-12-01 00:00:00
abstract::We consider inference for the reaction rates in discretely observed networks such as those found in models for systems biology, population ecology, and epidemics. Most such networks are neither slow enough nor small enough for inference via the true state-dependent Markov jump process to be feasible. Typically, infere...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12152
更新日期:2014-06-01 00:00:00
abstract::Laska and Meisner (1989, Biometrics 45, 1139-1151) dealt with the problem of testing whether an identified treatment belonging to a set of k + 1 treatments is better than each of the other k treatments. They calculated sample size tables for k = 2 when using multiple t-tests or Wilcoxon-Mann-Whitney tests, both under ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2000.00879.x
更新日期:2000-09-01 00:00:00
abstract::We propose optimal choice of the design parameters for random discontinuation designs (RDD) using a Bayesian decision-theoretic approach. We consider applications of RDDs to oncology phase II studies evaluating activity of cytostatic agents. The design consists of two stages. The preliminary open-label stage treats al...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2011.01623.x
更新日期:2012-03-01 00:00:00
abstract::Covariate-specific receiver operating characteristic (ROC) curves are often used to evaluate the classification accuracy of a medical diagnostic test or a biomarker, when the accuracy of the test is associated with certain covariates. In many large-scale screening tests, the gold standard is subject to missingness due...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2011.01562.x
更新日期:2011-09-01 00:00:00
abstract::In practice, when analyzing data from a capture-recapture experiment it is tempting to apply modern advanced statistical methods to the observed capture histories. However, unless the analysis takes into account that the data have only been collected from individuals who have been captured at least once, the results m...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2011.01596.x
更新日期:2011-12-01 00:00:00
abstract::In the calibration problem, the need to construct a confidence interval to estimate the unknown chi 0 arises when the null hypothesis of zero slope is rejected. Otherwise, the resulting confidence interval will be infinite to reflect the fact that the slope of the regression line may be zero. Under the condition of re...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::Quantitative traits analyzed in Genome-Wide Association Studies (GWAS) are often nonnormally distributed. For such traits, association tests based on standard linear regression are subject to reduced power and inflated type I error in finite samples. Applying the rank-based inverse normal transformation (INT) to nonno...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13214
更新日期:2020-12-01 00:00:00
abstract::We propose a likelihood-based test for comparing the means of two or more log-normal distributions, with possibly unequal variances. A modification to the likelihood ratio test is needed when sample sizes are small. The performance of the proposed procedures is compared with the F-ratio test using Monte Carlo simulati...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341X.2004.00199.x
更新日期:2004-06-01 00:00:00
abstract::In a presentation of various methods for assessing the sensitivity of regression results to unmeasured confounding, Lin, Psaty, and Kronmal (1998, Biometrics54, 948-963) use a conditional independence assumption to derive algebraic relationships between the true exposure effect and the apparent exposure effect in a re...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2008.01024.x
更新日期:2008-06-01 00:00:00
abstract::The estimation of maternal genetic variances by a multivariate maximum likelihood method is discussed. As an illustration the method is applied to data on Tribolium using a model based on partitioning the maternal genetic effect into additive and dominance components. An alternative model due to Falconer (1965) is als...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1976-12-01 00:00:00
abstract::Often with data from immunoassays, the concentration-response relationship is nonlinear and intra-assay response variance is heterogeneous. Estimation of the standard curve is usually based on a nonlinear heteroscedastic regression model for concentration-response, where variance is modeled as a function of mean respo...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::Patients who were previously treated for prostate cancer with radiation therapy are monitored at regular intervals using a laboratory test called Prostate Specific Antigen (PSA). If the value of the PSA test starts to rise, this is an indication that the prostate cancer is more likely to recur, and the patient may wis...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2012.01823.x
更新日期:2013-03-01 00:00:00
abstract::The "biometric school" founded by K. Pearson, F. Galton, and W. F. R. Weldon was concerned especially with heredity and variation, and between the wars "biometry" was not widely used as a general term for quantitative biology. The foundation of the Biometric Society encouraged this wider usage, and medical and biologi...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00