Memory in coal tits: an alternative model.

abstract：:The clinical trial design in which the endpoint is measured both at baseline and at the end of the study is used in a variety of situations. For two-group designs, test such as the t test or analysis of covariance are commonly used to evaluate treatment efficacy. Often such pretest-posttest trials restrict participati...

journal_title：Biometrics

authors： Follmann DA

更新日期：1991-06-01 00:00:00

abstract：:The validation of surrogate endpoints has been studied by Prentice (1989, Statistics in Medicine 8, 431-440) and Freedman, Graubard, and Schatzkin (1992, Statistics in Medicine 11, 167-178). We extended their proposals in the cases where the surrogate and the final endpoints are both binary or normally distributed. Le...

journal_title：Biometrics

authors： Buyse M,Molenberghs G

更新日期：1998-09-01 00:00:00

abstract：:The estimation of maternal genetic variances by a multivariate maximum likelihood method is discussed. As an illustration the method is applied to data on Tribolium using a model based on partitioning the maternal genetic effect into additive and dominance components. An alternative model due to Falconer (1965) is als...

journal_title：Biometrics

authors： Thompson R

更新日期：1976-12-01 00:00:00

abstract：:Epidemiological studies of related individuals are often complicated by the fact that follow-up on the event type of interest is incomplete due to the occurrence of other events. We suggest a class of frailty models with cause-specific hazards for correlated competing events in related individuals. The frailties are b...

journal_title：Biometrics

authors： Eriksson F,Scheike T

更新日期：2015-09-01 00:00:00

abstract：:Multivariate current status data, consist of indicators of whether each of several events occur by the time of a single examination. Our interest focuses on inferences about the joint distribution of the event times. Conventional methods for analysis of multiple event-time data cannot be used because all of the event ...

journal_title：Biometrics

authors： Dunson DB,Dinse GE

更新日期：2002-03-01 00:00:00

abstract：:We propose a nonparametric Bayesian approach to estimate the natural direct and indirect effects through a mediator in the setting of a continuous mediator and a binary response. Several conditional independence assumptions are introduced (with corresponding sensitivity parameters) to make these effects identifiable f...

journal_title：Biometrics

authors： Daniels MJ,Roy JA,Kim C,Hogan JW,Perri MG

更新日期：2012-12-01 00:00:00

abstract：:Inference for continuous time multi-state models presents considerable computational difficulties when the process is only observed at discrete time points with no additional information about the state transitions. In fact, for general multi-state Markov model, evaluation of the likelihood function is possible only v...

journal_title：Biometrics

authors： Tancredi A

更新日期：2019-09-01 00:00:00

abstract：:With increasing frequency, epidemiologic studies are addressing hypotheses regarding gene-environment interaction. In many well-studied candidate genes and for standard dietary and behavioral epidemiologic exposures, there is often substantial prior information available that may be used to analyze current data as wel...

journal_title：Biometrics

authors： Mukherjee B,Ahn J,Gruber SB,Ghosh M,Chatterjee N

更新日期：2010-09-01 00:00:00

abstract：:The concentration of carbon monoxide in the blood of a cigarette smoker varies in response to the frequency and dose of CO delivered by the cigarettes he smokes and by the rate at which CO washes out of his blood. Moments of first passage times or exit times above a nominal threshold can be calculated using a stochast...

journal_title：Biometrics

authors： Marcus AH,Czajkowski S Jr

更新日期：1979-09-01 00:00:00

abstract：:In diagnostic medicine, estimating the diagnostic accuracy of a group of raters or medical tests relative to the gold standard is often the primary goal. When a gold standard is absent, latent class models where the unknown gold standard test is treated as a latent variable are often used. However, these models have b...

journal_title：Biometrics

authors： Zhang B,Chen Z,Albert PS

更新日期：2012-12-01 00:00:00

abstract：:Geographic disease surveillance methods identify regions that have higher disease rates than expected. These approaches are generally applied to incident or prevalent cases of disease. In some contexts, disease-related events rather than individuals are the appropriate units of analysis for geographic surveillance. We...

journal_title：Biometrics

authors： Rosychuk RJ,Huston C,Prasad NG

更新日期：2006-06-01 00:00:00

abstract：:In this article, we describe a Bayesian approach to the calibration of a stochastic computer model of chemical kinetics. As with many applications in the biological sciences, the data available to calibrate the model come from different sources. Furthermore, these data appear to provide somewhat conflicting informatio...

journal_title：Biometrics

authors： Henderson DA,Boys RJ,Wilkinson DJ

更新日期：2010-03-01 00:00:00

abstract：:The distribution of ventilation-perfusion ratio over the lung is a useful indicator of the efficiency of lung function. Information about this distribution can be obtained by observing the retention in blood of inert gases passed through the lung. These retentions are related to the ventilation-perfusion distribution ...

journal_title：Biometrics

authors： Lim LL,Whitehead J

更新日期：1992-03-01 00:00:00

abstract：:We consider inference for the reaction rates in discretely observed networks such as those found in models for systems biology, population ecology, and epidemics. Most such networks are neither slow enough nor small enough for inference via the true state-dependent Markov jump process to be feasible. Typically, infere...

journal_title：Biometrics

authors： Fearnhead P,Giagos V,Sherlock C

更新日期：2014-06-01 00:00:00

abstract：:A life table estimates probabilities of surviving and of dying as well as death rates, as these would apply in a stationary population with the same underlying continuous mortality curve as the observed population. We have derived approximations to the probability of surviving that require no iteration, do not depend ...

journal_title：Biometrics

authors： Keyfitz N,Frauenthal J

更新日期：1975-12-01 00:00:00

abstract：:Brain evoked potential (EP) data consist of a true response ("signal") and random background activity ("noise"), which are observed over repeated stimulus presentations ("trials"). A signal that changes slowly from trial to trial can be estimated by smoothing across trials and over time within trials. We present a met...

journal_title：Biometrics

authors： Raz J,Turetsky B,Fein G

更新日期：1989-09-01 00:00:00

abstract：:Estimating the number of clusters in a data set is a crucial step in cluster analysis. In this article, motivated by the gap method (Tibshirani, Walther, and Hastie, 2001, Journal of the Royal Statistical Society B63, 411-423), we propose the weighted gap and the difference of difference-weighted (DD-weighted) gap met...

journal_title：Biometrics

authors： Yan M,Ye K

更新日期：2007-12-01 00:00:00

abstract：:Traditional paradigms for clinical translation are challenged in settings where multiple contemporaneous therapeutic strategies have been identified as potentially beneficial. Platform trials have emerged as an approach for sequentially comparing multiple trials using a single protocol. The Ebola virus disease outbrea...

journal_title：Biometrics

authors： Kaizer AM,Hobbs BP,Koopmeiners JS

更新日期：2018-09-01 00:00:00

abstract：:In multivariate failure time data analysis, a marginal regression modeling approach is often preferred to avoid assumptions on the dependence structure among correlated failure times. In this paper, a marginal mixed baseline hazards model is introduced. Estimating equations are proposed for the estimation of the margi...

journal_title：Biometrics

authors： Clegg LX,Cai J,Sen PK

更新日期：1999-09-01 00:00:00

abstract：:Patients who were previously treated for prostate cancer with radiation therapy are monitored at regular intervals using a laboratory test called Prostate Specific Antigen (PSA). If the value of the PSA test starts to rise, this is an indication that the prostate cancer is more likely to recur, and the patient may wis...

journal_title：Biometrics

authors： Taylor JM,Park Y,Ankerst DP,Proust-Lima C,Williams S,Kestin L,Bae K,Pickles T,Sandler H

更新日期：2013-03-01 00:00:00

abstract：:We introduce a nearly automatic procedure to locate and count the quantum dots in images of kinesin motor assays. Our procedure employs an approximate likelihood estimator based on a two-component mixture model for the image data; the first component has a normal distribution, and the other component is distributed as...

journal_title：Biometrics

authors： Hughes J,Fricks J

更新日期：2011-06-01 00:00:00

abstract：:Given data from bilateral visual assessments on N subjects at k occasions, we consider inference for contralateral correlations (C) between fellow eyes and lateral correlations (L) among p different assessments of the same eye. Under permutation symmetric dependence structure between observations from fellow eyes and ...

journal_title：Biometrics

authors： Viana M,Olkin I

更新日期：2000-12-01 00:00:00

abstract：:A simple method for comparing independent groups of clustered binary data with group-specific covariates is proposed. It is based on the concepts of design effect and effective sample size widely used in sample surveys, and assumes no specific models for the intracluster correlations. It can be implemented using any s...

journal_title：Biometrics

authors： Rao JN,Scott AJ

更新日期：1992-06-01 00:00:00

abstract：:The objective of this article is to develop a hypothesis-testing procedure to determine whether a common source outbreak has ended. We consider the case when neither the calendar date of exposure to the pathogen nor the exact incubation period distribution is known. The hypothesis-testing procedure is based on the spa...

journal_title：Biometrics

authors： Brookmeyer R,You X

更新日期：2006-03-01 00:00:00

abstract：:Procedures for estimating the genetic parameters of plant populations frequently employ progeny testing to ascertain the genotype of maternal plants. However, when experimental resources are limited (e.g., electrophoretic markers), the large progeny sizes required for accurate typing severely restricts the numbers of ...

journal_title：Biometrics

authors： Brown AH

更新日期：1975-03-01 00:00:00

abstract：:A full-likelihood procedure is proposed for analyzing correlated binary data under the assumption of exchangeability. The binomial and beta-binomial models are shown to occur as special cases correspondingly, respectively, to the choice of degenerate and beta-mixing distributions. For a finite exchangeable binary sequ...

journal_title：Biometrics

authors： George EO,Bowman D

更新日期：1995-06-01 00:00:00

abstract：:In longitudinal studies and in clustered situations often binary and continuous response variables are observed and need to be modeled together. In a recent publication Dunson, Chen, and Harry (2003, Biometrics 59, 521-530) (DCH) propose a Bayesian approach for joint modeling of cluster size and binary and continuous ...

journal_title：Biometrics

authors： Gueorguieva RV

更新日期：2005-09-01 00:00:00

abstract：:In clinical trials and other investigations of survival time, information is often available on a time-dependent event other than survival. An example of such an auxiliary event in cancer studies is objective progression of disease. While some patients expire without experiencing objective disease progression, others ...

journal_title：Biometrics

authors： Lagakos SW

更新日期：1976-09-01 00:00:00

abstract：:Many statistical tests have been proposed for case-control data to detect disease association with multiple single nucleotide polymorphisms (SNPs) in linkage disequilibrium. The main reason for the existence of so many tests is that each test aims to detect one or two aspects of many possible distributional difference...

journal_title：Biometrics

authors： Han F,Pan W

更新日期：2012-03-01 00:00:00

abstract：:Matched case-control designs are commonly used in epidemiologic studies for increased efficiency. These designs have recently been introduced to the setting of modern imaging and genomic studies, which are characterized by high-dimensional covariates. However, appropriate statistical analyses that adjust for the match...

journal_title：Biometrics

authors： Qian J,Payabvash S,Kemmling A,Lev MH,Schwamm LH,Betensky RA

更新日期：2014-03-01 00:00:00