Persistence of rickettsiae in the partially viable gangrenous margins of amputated extremities 5 to 7 weeks after onset of Rocky Mountain spotted fever.

Abstract:

:A case of Rocky Mountain spotted fever complicated by gangrene of the extremities required amputation and showed persistent rickettsial infection in the margins of the gangrene at 5 and 7 weeks after onset of illness. Rickettsial organisms were demonstrated by immunoperoxidase staining in the viable endothelial cells in the ischemic margins of the gangrenous tissue. We conclude that the cellular, humoral, and pharmacologic components that lead to eradication of the rickettsiae were not delivered to the ischemic margins at effective antirickettsial concentrations.

journal_name

Arch Pathol Lab Med

authors

Hove MG,Walker DH

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

429-31

issue

5

eissn

0003-9985

issn

1543-2165

journal_volume

119

pub_type

杂志文章
  • Unexpected autopsy findings arising from postmortem ocular examination.

    abstract:BACKGROUND:A full autopsy at our institution includes removal of the eyes for pathologic examination. To our knowledge, the rate of ophthalmic findings at autopsy has not been documented previously. DESIGN:We retrospectively reviewed 277 consecutive autopsies conducted between 1995 and 1999 in which the eyes were remo...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2001)125<1193:UAFAFP>2.0.CO;2

    authors: Butnor KJ,Proia AD

    更新日期:2001-09-01 00:00:00

  • The Differential Diagnosis of Reparative Changes and Malignancy: Performance in the College of American Pathologists Pap Education and Proficiency Testing Programs.

    abstract:CONTEXT.—:Repair is a challenging diagnosis and a significant source of false-positive (FP) interpretations in cervical cytology. No large-scale study of performance of repair in the liquid-based era has been performed. OBJECTIVE.—:To evaluate the performance of repair in the College of American Pathologists Pap Educa...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2019-0298-CP

    authors: Staats PN,Souers RJ,Nunez AL,Li Z,Kurtycz DFI,Goodrich K,Witt BL,Davey DD,Booth CN

    更新日期:2019-11-22 00:00:00

  • Endocrine manifestations of von Hippel-Lindau disease.

    abstract::von Hippel-Lindau (VHL) disease is an autosomal dominant disorder caused by heterozygous mutations in the VHL tumor suppressor gene that is characterized by the occurrence of multiple endocrine and nonendocrine lesions. This review focuses on the endocrine manifestations of VHL disease. Pancreatic neuroendocrine proli...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/arpa.2013-0520-RS

    authors: Cassol C,Mete O

    更新日期:2015-02-01 00:00:00

  • Campylobacter fetus sepsis with mycotic aortic aneurysm.

    abstract::Campylobacter fetus is a fastidious, curved, Gram-negative bacillus that has been increasingly associated with human disease. To our knowledge, we are reporting the first documented case of C fetus sepsis associated with an aortic mycotic aneurysm. Typical of previously reported cases of infections caused by this orga...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: File TM Jr,Barnishan J,Fass RJ

    更新日期:1979-03-01 00:00:00

  • Cytology Smears in the Era of Molecular Biomarkers in Non-Small Cell Lung Cancer: Doing More With Less.

    abstract:CONTEXT:- The rapid advances in targeted therapies in non-small cell lung cancer (NSCLC) make the optimization and implementation of cytology specimens for molecular testing a priority. Up to 70% of patients with NSCLC are diagnosed at advanced stages and tissue biopsies often cannot be taken. Although cytology samples...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/arpa.2017-0208-RA

    authors: Lozano MD,Echeveste JI,Abengozar M,Mejías LD,Idoate MA,Calvo A,de Andrea CE

    更新日期:2018-03-01 00:00:00

  • Review of pediatric autopsies performed at a university hospital in Ribeirão Preto, Brazil.

    abstract:CONTEXT:Autopsy continues to provide important data for quality assurance, teaching, scientific purposes, and health planning, especially if performed according to a comprehensive protocol. OBJECTIVE:To describe and analyze data from all perinatal and pediatric autopsies performed at a university hospital in Brazil. ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2006)130[62:ROPAPA]2.0.CO;2

    authors: Peres LC

    更新日期:2006-01-01 00:00:00

  • Continuum of the thickness of surviving myocardial wall with single myocardial infarcts.

    abstract::The pathologic correlate of the clinical terms subendocardial and transmural applied to myocardial infarcts is uncertain. To examine this question, we reviewed the morphology of 204 hearts with single myocardial infarcts studied at autopsy after coronary arteriography and fixation in distention. The thickness of survi...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Pirolo JS,Moore GW,Hutchins GM

    更新日期:1986-05-01 00:00:00

  • Granulomatous dermatitis due to Malassezia sympodialis.

    abstract::A 67-year-old man, with multiple skin lesions that appeared over 2 years, had biopsies that disclosed granulomatous dermatitis with associated small yeasts. The urinary antigen test results were negative for Histoplasma infection; cultures from the biopsies did not grow any fungi or other potential pathogens. The ches...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/2010-0588-CRR.1

    authors: Desai HB,Perkins PL,Procop GW

    更新日期:2011-09-01 00:00:00

  • Low-grade B-cell lymphoma and concomitant extensive sarcoidlike granulomas: a case report and review of the literature.

    abstract::Sarcoidlike granulomas may occur in association with Hodgkin lymphoma and non-Hodgkin lymphoma. The granulomas may be concomitant and so extensive that they obscure the malignant process. In addition, a sarcoidosis-lymphoma syndrome has been described in which there appears to be a relationship between sarcoidosis and...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/0003-9985(2000)124<0152:LGBCLA>2.0.CO;2

    authors: Dunphy CH,Panella MJ,Grosso LE

    更新日期:2000-01-01 00:00:00

  • Cytosine arabinoside substitution decreases transcription factor-DNA binding element complex formation.

    abstract:CONTEXT:The pyrimidine nucleoside analog, cytosine arabinoside (Ara-C), is an effective therapeutic agent for acute leukemia. The phosphorylated triphosphate, cytosine arabinoside triphosphate, competes with deoxycytosine triphosphate as a substrate for incorporation into DNA. Once incorporated into DNA, it inhibits DN...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2004)128<1364:CASDTF>2.0.CO;2

    authors: Zhang X,Kiechle FL

    更新日期:2004-12-01 00:00:00

  • Cutaneous angiosarcoma complicating morbid obesity.

    abstract::Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a m...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2001)125<0531:CACMO>2.0.CO;2

    authors: Azam M,Saboorian H,Bieligk S,Smith T,Molberg K

    更新日期:2001-04-01 00:00:00

  • A Historical Perspective and Exposé on Serrated Polyps of the Colorectum.

    abstract::This article offers a historical perspective on the discovery of 3 types of serrated colorectal polyps recognized in the past 60 years. The first to be discovered was the hyperplastic polyp, which is still the most commonly encountered serrated polyp. In the past 20 years, the carcinoma-associated sessile serrated ade...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.5858/arpa.2016-0278-RA

    authors: Choi EY,Appelman HD

    更新日期:2016-10-01 00:00:00

  • Umbilical cord lesions in early intrauterine fetal demise.

    abstract:CONTEXT:The cause for intrauterine fetal demise (IUFD) occurring in early gestation in a high percentage of spontaneous abortions is unknown. OBJECTIVE:To determine the association, if any, of umbilical cord abnormalities with early IUFD. DESIGN:All cases of IUFD occurring within 16 weeks of gestation that presented ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2003)127<850:UCLIEI>2.0.CO;2

    authors: Singh V,Khanum S,Singh M

    更新日期:2003-07-01 00:00:00

  • Sclerosing hyaline necrosis of the liver in Bloom syndrome.

    abstract::Bloom syndrome is a rare autosomal recessive disorder characterized by normally proportioned but strikingly small body size, a characteristic facies and photosensitive facial skin lesion, immunodeficiency, and a marked predisposition to development of a variety of cancers. We describe here, we believe for the first ti...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(1999)123<0346:SHNOTL>2.0.CO;2

    authors: Wang J,Cornford ME,German J,French SW

    更新日期:1999-04-01 00:00:00

  • Effective management of hepatitis C molecular testing improves test use without compromising patient management.

    abstract:CONTEXT:The availability of effective antiviral therapy for hepatitis C has increased the need for molecular detection and quantification of circulating hepatitis C viral particles. The limits of detection differ for the quantitative and qualitative reverse transcriptase polymerase chain reaction (RT-PCR) assays; furth...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/0003-9985(2002)126<0100:EMOHCM>2.0.CO;2

    authors: Kukuczka S,Grosso LE

    更新日期:2002-01-01 00:00:00

  • North American pretransfusion testing practices, 2001-2004: results from the College of American Pathologists Interlaboratory Comparison Program survey data, 2001-2004.

    abstract:CONTEXT:Pretransfusion testing of whole blood and red blood cell recipients is regulated by the federal government under the authority of the Clinical Laboratory Improvement Amendments of 1988. Regulated tests include determination of ABO group, Rh D type, antibody detection, antibody identification, and crossmatching....

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1043/1543-2165(2005)129[984:NAPTPR]2.0.CO;2

    authors: Shulman IA,Maffei LM,Downes KA

    更新日期:2005-08-01 00:00:00

  • Latent membrane protein 1, tumor necrosis factor receptor-associated factor (TRAF) 1, TRAF-2, TRAF-3, and nuclear factor kappa B expression in posttransplantation lymphoproliferative disorders.

    abstract:CONTEXT:Most posttransplantation lymphoproliferative disorders (PTLDs) are associated with Epstein-Barr virus (EBV) infection. The EBV latent membrane protein 1 (LMP-1) is important in the transformation of B lymphocytes through its interaction with intracellular tumor necrosis factor receptor-associated factors (TRAFs...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2003)127<1335:LMPTNF>2.0.CO;2

    authors: Ramalingam P,Chu WS,Tubbs R,Rybicki L,Pettay J,Hsi ED

    更新日期:2003-10-01 00:00:00

  • Disseminated toxoplasmosis in the acquired immunodeficiency syndrome.

    abstract::Fourteen cases of toxoplasmosis in subjects at autopsy with acquired immunodeficiency syndrome are reviewed. Death was related to toxoplasmosis in four cases: in three from central nervous system complications and in one case from myocarditis. In six cases the infection was identified outside of the central nervous sy...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Tschirhart D,Klatt EC

    更新日期:1988-12-01 00:00:00

  • Histochemical classification of systemic amyloid fibril proteins. Alkaline guanidine method.

    abstract::The alkaline guanidine method facilitates differentiation between different types of amyloid fibril proteins in formaldehyde-fixed, paraffin-embedded tissue sections. Systemic AA-type amyloids lost Congophilia (affinity of Congo red) after incubation with alkaline guanidine for one minute. Systemic AL-type amyloids lo...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Tashima T,Kitamoto T,Tateishi J

    更新日期:1986-10-01 00:00:00

  • Practice guidelines for autopsy pathology. Autopsy performance. Autopsy Committee of the College of American Pathologists.

    abstract::The Autopsy Committee of the College of American Pathologists has prepared this guideline in conjunction with representatives of other organizations to assist pathologists in the performance of autopsies. The guideline is to be regarded as being primarily an educational tool. Application of these recommendations on au...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 指南,杂志文章

    doi:

    authors: Hutchins GM

    更新日期:1994-01-01 00:00:00

  • Detection of adenocarcinoma in situ of the cervix in Papanicolaou tests: comparison of diagnostic accuracy with other high-grade lesions.

    abstract:CONTEXT:Adenocarcinoma in situ of the cervix is a recently recognized interpretation in the Bethesda 2001 system. Although specific morphologic criteria have been published, recognizing this entity is still difficult. OBJECTIVE:To compare pathologists' ability to correctly identify and categorize adenocarcinoma in sit...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2004)128<153:DOAISO>2.0.CO;2

    authors: Renshaw AA,Mody DR,Lozano RL,Volk EE,Walsh MK,Davey DD,Birdsong GG

    更新日期:2004-02-01 00:00:00

  • Antithrombin deficiency: issues in laboratory diagnosis.

    abstract:OBJECTIVE:To review the current understanding of the pathophysiology of antithrombin deficiency and its role in congenital thrombophilia. Recommendations for diagnostic testing of antithrombin function and concentration, derived from the medical literature and consensus opinions of recognized experts in the field, are ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章,评审

    doi:10.1043/0003-9985(2002)126<1326:AD>2.0.CO;2

    authors: Kottke-Marchant K,Duncan A

    更新日期:2002-11-01 00:00:00

  • Recent studies on 'hyalinized' glomeruli.

    abstract::Hyalinized glomeruli in tissue sections those isolated from kidneys of subjected with end-stage and diabetic nephropathies and from aged persons (older than 75 years) were studied by histochemical, immunohistochemical, electron microscopic, and chemical methods. Our purposes were as follows: (1) to clarify the pathoge...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Misra RP

    更新日期:1981-11-01 00:00:00

  • Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling.

    abstract:CONTEXT:The differential diagnosis of eosinophilic renal tumors can be difficult by light microscopy. In particular, chromophobe renal cell carcinoma (RCC) is difficult to distinguish from oncocytoma. This differential diagnosis is important because chromophobe RCC is malignant, whereas oncocytoma is benign. Furthermor...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2007)131[1541:CIIRTA]2.0.CO;2

    authors: Hornsby CD,Cohen C,Amin MB,Picken MM,Lawson D,Yin-Goen Q,Young AN

    更新日期:2007-10-01 00:00:00

  • Concomitant Epstein-Barr virus-negative large B-cell lymphoma (Richter syndrome) and Epstein-Barr virus- positive B-cell lymphoproliferation after treatment with fludarabine and cyclophosphamide in a patient with B-cell chronic lymphocytic leukemia.

    abstract::We report the case of a patient treated with a combination of fludarabine and cyclophosphamide after suffering from B-cell chronic lymphocytic leukemia for 10 years. Three months after treatment, the patient presented with an unusual association, not previously reported in the literature: Richter syndrome (monotypic E...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165(2006)130[1227:CEVLBL]2.0.CO;2

    authors: Compérat E,Delmer A,Le Tourneau A,Molina TJ,Diebold J,Audouin J

    更新日期:2006-08-01 00:00:00

  • Frozen section and the surgical pathologist: a point of view.

    abstract::Frozen section is a prominent point of intersection between surgeons and pathologists. It is regarded as the most definitive--but not the sole--form of intraoperative consultation. Its role in tissue triage, diagnosis, and intraoperative management should not be misconstrued as a shortcut to a definitive diagnosis. Al...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.1043/1543-2165-133.7.1135

    authors: Taxy JB

    更新日期:2009-07-01 00:00:00

  • Dialysis enhances renal epithelial proliferations.

    abstract::Study of 115 kidneys from 60 patients with chronic renal failure maintained by dialysis for two months to five years revealed an unexpected number and variety of epithelial proliferative processes, several types of which are hitherto unreported. Proliferative activity was defined either by the presence of epithelial s...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: McManus JF,Hughson MD,Hennigar GR,Fitts CT,Rajagopalan PR,Williams AV

    更新日期:1980-04-01 00:00:00

  • Antithrombin levels are unaffected by warfarin use.

    abstract:CONTEXT:The results of studies among patients with antithrombin deficiency have suggested that the use of warfarin will increase the level of antithrombin. OBJECTIVE:To reevaluate the effect of warfarin on antithrombin levels using an automated amidolytic method in current use. DESIGN:Antithrombin levels were measure...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:10.5858/arpa.2013-0065-OA

    authors: Sanfelippo MJ,Engel JM,Onitilo AA

    更新日期:2014-07-01 00:00:00

  • Light microscopy techniques for the demonstration of silicone gel.

    abstract::Because of the difficulty in identifying silicone gel in histologic and cytologic specimens by means of conventional light microscopy, we investigated alternative light microscopy techniques, as well as specimen staining and preparation. Specimens from six periprosthetic capsules, one silicone granuloma specimen, and ...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Raso DS,Greene WB,Vesely JJ,Willingham MC

    更新日期:1994-10-01 00:00:00

  • Focal glomerular sclerosis and sarcoidosis.

    abstract::Idiopathic nephrotic syndrome occurred in a patient with sarcoidosis. Typical features of focal segmental glomerulosclerosis were present on kidney biopsy. A unique finding was the occurrence of IgA in blood vessels of the skin and lymph node. Whereas the sarcoid hilar adenopathy responded to steroid therapy, the neph...

    journal_title:Archives of pathology & laboratory medicine

    pub_type: 杂志文章

    doi:

    authors: Lee SM,Michael AF

    更新日期:1978-11-01 00:00:00