Focal glomerular sclerosis and sarcoidosis.

Abstract:

:Idiopathic nephrotic syndrome occurred in a patient with sarcoidosis. Typical features of focal segmental glomerulosclerosis were present on kidney biopsy. A unique finding was the occurrence of IgA in blood vessels of the skin and lymph node. Whereas the sarcoid hilar adenopathy responded to steroid therapy, the nephrotic syndrome was resistant to steroids and immunosuppression. Evaluation of humoral and cellular immune responsiveness showed no abnormalities except cutaneous anergy. Glomerulonephritis is uncommon in sarcoidosis, and a brief outline of this association is included. This patient is of importance in view of the unexplained relationship between idiopathic nephrotic syndrome and T lymphocyte abnormalities.

journal_name

Arch Pathol Lab Med

authors

Lee SM,Michael AF

subject

Has Abstract

pub_date

1978-11-01 00:00:00

pages

572-5

issue

11

eissn

0003-9985

issn

1543-2165

journal_volume

102

pub_type

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