Decrease in anti-Proteus mirabilis but not anti-Escherichia coli antibody levels in rheumatoid arthritis patients treated with fasting and a one year vegetarian diet.

abstract：OBJECTIVE:To describe the associations between overweight measures in childhood and knee pain, stiffness and dysfunction among adults 25 years later. METHODS:Subjects broadly representative of the Australian population (n=449, aged 31-41 years, female 48%) were selected from the Australian Schools Health and Fitness S...

journal_title：Annals of the rheumatic diseases

authors： Antony B,Jones G,Venn A,Cicuttini F,March L,Blizzard L,Dwyer T,Cross M,Ding C

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:To develop evidence-based EULAR recommendations for cardiovascular (CV) risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA). METHODS:A multidisciplinary expert committee was convened as a task force of the EULAR Standing Committee for Clinica...

journal_title：Annals of the rheumatic diseases

authors： Peters MJ,Symmons DP,McCarey D,Dijkmans BA,Nicola P,Kvien TK,McInnes IB,Haentzschel H,Gonzalez-Gay MA,Provan S,Semb A,Sidiropoulos P,Kitas G,Smulders YM,Soubrier M,Szekanecz Z,Sattar N,Nurmohamed MT

更新日期：2010-02-01 00:00:00

abstract：:No consensus has previously been formed regarding the types and presentations of infectious pathogens to be considered as 'opportunistic infections' (OIs) within the setting of biologic therapy. We systematically reviewed published literature reporting OIs in the setting of biologic therapy for inflammatory diseases. ...

journal_title：Annals of the rheumatic diseases

authors： Winthrop KL,Novosad SA,Baddley JW,Calabrese L,Chiller T,Polgreen P,Bartalesi F,Lipman M,Mariette X,Lortholary O,Weinblatt ME,Saag M,Smolen J

更新日期：2015-12-01 00:00:00

abstract：:The effect of two gold(I) compounds on stability of lysosomes in vitro was studied. Lysosomes from homogenates of rat kidney cortex were isolated by differential centrifugation. These lysosomes were incubated at 37 degrees C with widely varied concentrations of sodium aurothiomalate and sodium aurothiosulphate for 5, ...

journal_title：Annals of the rheumatic diseases

authors： Graabaek PM,Pedersen SM

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:To assess associations between joint-specific hand symptoms and self-reported and performance-based functional status. METHODS:Participants were from the population-based Johnston County Osteoarthritis Project. Symptoms in the distal interphalangeal (DIP), proximal interphalangeal (PIP), first carpometacarpa...

journal_title：Annals of the rheumatic diseases

authors： Elliott AL,Kraus VB,Fang F,Renner JB,Schwartz TA,Salazar A,Huguenin T,Hochberg MC,Helmick CG,Jordan JM

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To evaluate radiographic features of osteoarthritis (OA) to determine which is more closely associated with knee pain and hence might be used as a radiographic definition of OA in the community. To evaluate joint space width in normal subjects. METHODS:452 subjects from a case-control community study of knee...

journal_title：Annals of the rheumatic diseases

authors： Lanyon P,O'Reilly S,Jones A,Doherty M

更新日期：1998-10-01 00:00:00

abstract：:Peripheral and axial bone mass and fracture incidence were studied in a group of 104 postmenopausal patients with rheumatoid arthritis (RA). Patients were divided into non-corticosteroid and low dose corticosteroid treated groups after elimination of patients with concomitant disease or therapy which might affect bone...

journal_title：Annals of the rheumatic diseases

authors： Verstraeten A,Dequeker J

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVES:Hyperplasia of synovial fibroblasts, infiltration with lymphocytes and tissue hypoxia are major characteristics of rheumatoid arthritis (RA). Extensive data support a key role for toll-like receptors (TLRs) in RA. Little is known regarding the impact of hypoxia on TLR-induced inflammation in RA. The aim of t...

journal_title：Annals of the rheumatic diseases

authors： Hu F,Mu R,Zhu J,Shi L,Li Y,Liu X,Shao W,Li G,Li M,Su Y,Cohen PL,Qiu X,Li Z

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:IKZF1 and IKZF3 (encoding transcription factors Ikaros and Aiolos) are susceptibility loci for systemic lupus erythematosus (SLE). The pharmacology of iberdomide (CC-220), a cereblon (CRBN) modulator targeting Ikaros and Aiolos, was studied in SLE patient cells and in a phase 1 healthy volunteer study. METH...

journal_title：Annals of the rheumatic diseases

authors： Schafer PH,Ye Y,Wu L,Kosek J,Ringheim G,Yang Z,Liu L,Thomas M,Palmisano M,Chopra R

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Several studies suggest a role of the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis in the pathophysiology of primary osteoarthritis (OA). A common polymorphism of the GH receptor (exon 3 deletion, d3-GHR) is associated with increased GH/IGF-1 activity. OBJECTIVE:To study associations betwee...

journal_title：Annals of the rheumatic diseases

authors： Claessen KM,Kloppenburg M,Kroon HM,Bijsterbosch J,Pereira AM,Romijn JA,van der Straaten T,Nelissen RG,Hofman A,Uitterlinden AG,Duijnisveld BJ,Lakenberg N,Beekman M,van Meurs JB,Slagboom PE,Biermasz NR,Meulenbelt I

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:To assess the effect of an intra-articular presentation of stress (heat shock) proteins (hsp) on joint inflammation. METHODS:Wistar rats were sensitised with a suspension of heat killed Mycobacterium tuberculosis in oil in the scruff of the neck and challenged intra-articularly with stress protein or M tube...

journal_title：Annals of the rheumatic diseases

authors： Winrow VR,Ragno S,Morris CJ,Colston MJ,Mascagni P,Leoni F,Gromo G,Coates AR,Blake DR

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Individuals with psoriasis have increased blood levels of uric acid. However, there is no prospective data on the association between psoriasis and uric acid levels and subsequent development of gout. In this study, we examined the risk of gout among individuals with psoriasis and psoriatic art...

journal_title：Annals of the rheumatic diseases

authors： Merola JF,Wu S,Han J,Choi HK,Qureshi AA

更新日期：2015-08-01 00:00:00

abstract：:Results are reported from the first prospective study of gout in New Zealand Maoris based on a sample of 388 males and 378 females. At baseline, high mean levels of serum uric acid (SUA) were found, 0.422 +/- 0.092 mmol/1 (7.05 +/- 1.54 mg/100 ml) in males and 0.350 +/- 0.091 mmol/1 (5.85 +/- 1.52 mg/100 ml) in female...

journal_title：Annals of the rheumatic diseases

authors： Brauer GW,Prior IA

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Qualitative differences in synovitis between the cartilage-pannus junction (CPJ) region and the adjoining suprapatellar pouch (SPP) have been reported in rheumatoid arthritis and the spondyloarthropathies. OBJECTIVE:To determine if the distribution of synovitis is the same in osteoarthritis (OA) using sensi...

journal_title：Annals of the rheumatic diseases

authors： Rhodes LA,Conaghan PG,Radjenovic A,Grainger AJ,Emery P,McGonagle D

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The 2010 ACR/EULAR classification criteria for rheumatoid arthritis (RA) were developed to improve the identification of individuals for studies of RA. We aimed to summarise the performance of the criteria based on the published literature. METHODS:We performed a systematic literature search to identify all...

journal_title：Annals of the rheumatic diseases

authors： Radner H,Neogi T,Smolen JS,Aletaha D

更新日期：2014-01-01 00:00:00

abstract：:In a multicentre study patients with rheumatoid arthritis judged by prevailing criteria to be suitable for synovectomy of the knee or metacarpophalangeal (MCP) joints were randomly allocated to one of two groups. One group had the operation, the other was observed without operation from a notional corresponding date. ...

journal_title：Annals of the rheumatic diseases

authors：

更新日期：1975-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether type II collagen (CII) is recognised by oligoclonally expanded synovial T cells of patients with rheumatoid arthritis (RA). METHODS:Peripheral blood mononuclear cells (PBMC) from 15 RA patients were stimulated with CII in vitro. T cell clones expanded by such stimulation were compared ...

journal_title：Annals of the rheumatic diseases

authors： Sekine T,Kato T,Masuko-Hongo K,Nakamura H,Yoshino S,Nishioka K,Yamamoto K

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:Notch signalling pathways are critical for angiogenesis and endothelial cell (EC) fate; however the mechanisms regulating these processes in the inflamed joint remain to be elucidated. Here, we examine whether Notch signalling mediates vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang2)-induce...

journal_title：Annals of the rheumatic diseases

authors： Gao W,Sweeney C,Walsh C,Rooney P,McCormick J,Veale DJ,Fearon U

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To determine whether continued methotrexate treatment increases the risk of postoperative infections or of surgical complications in patients with rheumatoid arthritis (RA) within one year of elective orthopaedic surgery. DESIGN:A prospective randomised study of postoperative infection or surgical complicat...

journal_title：Annals of the rheumatic diseases

authors： Grennan DM,Gray J,Loudon J,Fear S

更新日期：2001-03-01 00:00:00

abstract：:One of the proposed mechanisms of vascular damage in connective tissue disease is the direct action of a cytotoxic serum factor inducing endothelial cell damage. The nature of this serum factor is unclear, but has been suggested to be a lipoprotein. Sera from patients with (1) systemic necrotising arteritis (polyarter...

journal_title：Annals of the rheumatic diseases

authors： Blake DR,Winyard P,Scott DG,Brailsford S,Blann A,Lunec J

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVES:To measure hyaluronic acid (HA) levels, which are raised in active rheumatoid arthritis (RA), in patients with early RA, and to assess the correlation with clinical and laboratory indices of disease activity and with subsequent radiographic erosive status. PATIENTS AND METHODS:Patients fulfilling ACR criter...

journal_title：Annals of the rheumatic diseases

authors： Majeed M,McQueen F,Yeoman S,McLean L

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Increased subchondral bone turnover may contribute to pain in osteoarthritis (OA). OBJECTIVES:To investigate the analgesic potential of a modified version of osteoprotegerin (osteoprotegerin-Fc (OPG-Fc)) in the monosodium iodoacetate (MIA) model of OA pain. METHODS:Male Sprague Dawley rats (140-260 g) were...

journal_title：Annals of the rheumatic diseases

authors： Sagar DR,Ashraf S,Xu L,Burston JJ,Menhinick MR,Poulter CL,Bennett AJ,Walsh DA,Chapman V

更新日期：2014-08-01 00:00:00

abstract：:Two cases of bilateral shoulder-hand syndrome and symmetrical arthralgia are described in patients with tubo-ovarian carcinoma. Swelling and contracture of the hands continued to develop despite oral corticosteroid therapy, and one patient underwent surgery in an attempt to prevent the development of further deformity...

journal_title：Annals of the rheumatic diseases

authors： Taggart AJ,Iveson JM,Wright V

更新日期：1984-06-01 00:00:00

abstract：:A 17-year-old female patient with systemic lupus erythematosus (SLE) developed chronic tophaceous gout, chondrocalcinosis and articular capsule calcification in several joints. Analysis of synovial fluid and tophi revealed the coexistence of monosodium urate, calcium pyrophosphate, hydroxyapatite, and cholesterol crys...

journal_title：Annals of the rheumatic diseases

authors： Rodríguez MA,Paul H,Abadí I,Bravo JR,Armas P

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVES:Previous evidence suggests the role of psychological stress in triggering the onset of autoimmunity. We aimed to investigate whether stress following major and minor life events could precede the onset of primary Sjögren's syndrome (pSS). The role of coping strategies and social support, as compensating buff...

journal_title：Annals of the rheumatic diseases

authors： Karaiskos D,Mavragani CP,Makaroni S,Zinzaras E,Voulgarelis M,Rabavilas A,Moutsopoulos HM

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:With the tools available currently, confirming the diagnosis of inclusion body myositis (IBM) can be difficult. Many patients are initially misdiagnosed with polymyositis (PM). In this observational study at a UK adult neuromuscular centre, we investigated whether amyloid positron emission tomography could d...

journal_title：Annals of the rheumatic diseases

authors： Lilleker JB,Hodgson R,Roberts M,Herholz K,Howard J,Hinz R,Chinoy H

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of a switch from oral methotrexate (MTX) to subcutaneous MTX (scMTX) or adding ciclosporin to oral MTX with a simultaneous reduction of the MTX dose, in case of adverse events (AE) or insufficient effect (IE) in rheumatoid arthritis (RA). METHODS:The tight control treatment arm of ...

journal_title：Annals of the rheumatic diseases

authors： Bakker MF,Jacobs JW,Welsing PM,van der Werf JH,Linn-Rasker SP,van der Veen MJ,Lafeber FP,Bijlsma JW,Utrecht Arthritis Cohort Study Group.

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:To estimate the prevalence and incidence of systemic sclerosis (SSc) in southern Sweden. METHODS:In Skåne, the southernmost region of Sweden (total population 1.2 million), healthcare provided is registered in the Skåne Healthcare Register. We identified all Skåne residents who had received an International...

journal_title：Annals of the rheumatic diseases

authors： Andréasson K,Saxne T,Bergknut C,Hesselstrand R,Englund M

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:To analyse the association between chondrocalcinosis and osteoarthritis (OA) of the hands and knees in an unselected elderly rural population. METHODS:A community based cross sectional study was performed in individuals randomly selected from a previous epidemiological survey on the prevalence of chondrocal...

journal_title：Annals of the rheumatic diseases

authors： Sanmarti R,Kanterewicz E,Pladevall M,Pañella D,Tarradellas JB,Gomez JM

更新日期：1996-01-01 00:00:00

abstract：:Of 29 524 hospitalised medical patients monitored in a drug surveillance programme 1835 (6.2%) received the xanthine oxidase inhibitor allopurinol. After the exclusion of skin reactions adverse effects were attributed to this drug in 33 (1.8%) patients, the most frequent being haematological abnormalities (11 patients...

journal_title：Annals of the rheumatic diseases

authors： McInnes GT,Lawson DH,Jick H

更新日期：1981-06-01 00:00:00