Effects of general anaesthetics on second messenger systems.

abstract：BACKGROUND:Infants undergoing general anaesthesia have an increased risk of severe respiratory and cardiovascular critical events. Awake caudal anaesthesia is an alternative for small infants undergoing minor lower abdominal surgery. While clinical experience has shown stable intra-operative haemodynamic conditions, th...

journal_title：European journal of anaesthesiology

authors： Beck CE,Sümpelmann R,Nickel K,Keil O,Kuebler JF,Boethig D,Witt L,Dennhardt N

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We assessed the analgesic efficacy of postoperative epidural infusions of ropivacaine 0.1 and 0.2% combined with sufentanil 1 microg mL(-1) in a prospective, randomized, double-blinded study. METHODS:Twenty-two ASA I-III patients undergoing elective total-knee replacement were included. Lumbar...

journal_title：European journal of anaesthesiology

authors： Kampe S,Diefenbach C,Kanis B,Auweiler M,Kiencke P,Cranfield K

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Administration of calcium safely and effectively reverses many of the electrophysiological actions of hyperkalaemia, but it has not been studied for pretreatment. Based on cellular studies, magnesium also has been suggested to prevent the effects of potassium on the heart. As their mechanisms o...

journal_title：European journal of anaesthesiology

authors： Hollmann MW,Strümper D,Salmons VA,Washington JM,Durieux ME

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Continuous positive airways pressure (CPAP) with a CPAP machine and mask has been shown to be more effective at minimising hypoxaemia than other devices under deep sedation. However, the efficacy of a new and simple CPAP device for spontaneously breathing obese patients during colonoscopy is unknown. OBJECT...

journal_title：European journal of anaesthesiology

authors： Bai Y,Xu Z,Chandrashekar M,St Jacques PJ,Liang Y,Jiang Y,Kla K

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Laparoscopic and open surgery have been compared with conflicting results regarding their systemic responses. The sensitivity of biochemical markers that are used to discriminate between the stress responses to different types of surgery varies from study to study. We wanted to evaluate the str...

journal_title：European journal of anaesthesiology

authors： Rorarius MG,Kujansuu E,Baer GA,Suominen P,Teisala K,Miettinen A,Ylitalo P,Laippala P

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Flexible fibreoptic endoscopic (FFE) intubation is considered the 'gold-standard' when difficult airway management is anticipated. Several videolaryngoscopes have been developed to facilitate intubation by laryngoscopy. OBJECTIVE:The aim of the study was to compare the performance of the McGrath series 5 vi...

journal_title：European journal of anaesthesiology

authors： Jepsen CH,Gätke MR,Thøgersen B,Mollerup LT,Ruhnau B,Rewers M,Rosenstock CV

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Previous studies have shown that L-type voltage-sensitive Ca2+ channel blocking agents increased and the L-type Ca2+ channel activator Bay K 8644 reduced the general anaesthetic potency in animals. As the bispectral index correlates with the depth of sedation, we examined whether L-type Ca2+ ch...

journal_title：European journal of anaesthesiology

authors： Hirota K,Kabara S,Kushikata T,Kitayama M,Ishihara H,Matsuki A

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Post-anaesthetic shivering is one of the most common complications, occurring in 5-65% of patients recovering from general anaesthesia and 33% of patients receiving epidural anaesthesia. Our objective was to investigate the efficacy of intraoperative dexmedetomidine infusion on postoperative shivering. METH...

journal_title：European journal of anaesthesiology

authors： Elvan EG,Oç B,Uzun S,Karabulut E,Coşkun F,Aypar U

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Alpha-2 agonists offer useful effects that make these drugs an interesting alternative for pharmacological premedication. METHODS:In a randomized, double-blind study, effects of clonidine (150 microg orally), midazolam (7.5 mg orally) and placebo administered 60-90 min prior to estimated anae...

journal_title：European journal of anaesthesiology

authors： Paris A,Kaufmann M,Tonner PH,Renz P,Lemke T,Ledowski T,Scholz J,Bein B

更新日期：2009-07-01 00:00:00

abstract：:Thirty-six children (mean age 2.4 years) premedicated with oral chloral hydrate 70 mg kg-1 and atropine 0.03 mg kg-1 were anaesthetized with either 3.75% isoflurane or 2.5% halothane in 70% nitrous oxide in oxygen. The eyelash reflex disappeared in 39 +/- 7 s (mean +/- SD) with isoflurane and in 56 +/- 16 s with halot...

journal_title：European journal of anaesthesiology

authors： Lindgren L,Randell T,Saarnivaara L

更新日期：1991-01-01 00:00:00

abstract：:Ringer's solution expands blood volume by between 20% and 25% in awake volunteers, but little is known about its volume effect during general anaesthesia. In 35 men with a mean age of 70 years, the power of various intra-operative factors to change blood volume as estimated by the haemoglobin dilution method were anal...

journal_title：European journal of anaesthesiology

authors： Hahn RG

更新日期：1998-07-01 00:00:00

abstract：:Intra-operative segmental wall motion abnormalities (SWMA) detected by transoesophageal echocardiography (TOE) have been shown to be a sensitive indicator of myocardial ischaemia. To determine the incidence and characteristics of segmental wall motion abnormalities and to relate these changes to perioperative myocardi...

journal_title：European journal of anaesthesiology

authors： Kolev N,Ihra G,Swanevelder J,Spiss CK,Hartmann T,Zimpfer M

更新日期：1997-07-01 00:00:00

abstract：:Two groups of 25 patients were sedated during neuroradiological investigation. The first group was sedated with fentanyl and midazolam while the other was given fentanyl and a two-stage infusion of propofol in a subanaesthetic dose. Both techniques resulted in satisfactory sedation and recovery, although those who rec...

journal_title：European journal of anaesthesiology

authors： Allan MW,Laurence AS,Gunawardena WJ

更新日期：1989-09-01 00:00:00

abstract：:The time profile of the neuromuscular block produced by a single bolus administration of vecuronium was simulated by a new model for the access of the relaxant to the receptors on the motor end plates. The receptors were assumed to be kinetically a part of the interstitial space of the muscle. The time course of the n...

journal_title：European journal of anaesthesiology

authors： Nigrovic V

更新日期：1994-03-01 00:00:00

abstract：:A 72-year-old woman had a minitracheostomy inserted for sputum retention. This was undertaken by a relatively junior resident who opted to use an early model minitracheostomy kit Minitrach II. The following day the patients condition deteriorated and intubation was warranted, at which time it was apparent to senior st...

journal_title：European journal of anaesthesiology

authors： Browne J,McShane D,Donnelly M

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In isolated-perfused lungs of lipopolysaccharide (LPS)-challenged rats, vasodilatation to inhaled nitric oxide (NO) is impaired. Inhibition of nitric oxide synthase 2 (NOS2) by aminoguanidine (AG) prevented hyporesponsiveness to inhaled NO. Here, we investigated whether NOS2-mediated nitrite/n...

journal_title：European journal of anaesthesiology

authors： Bopp Ch,Gust R,Taut F,Gries A,Martin E,Klein A

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Recent evidence indicates that platelet function may recover more rapidly after cessation of aspirin therapy than previously thought. The present study evaluated the effect of aspirin on platelet function using platelet aggregometry in healthy individuals and in aspirin-treated patients schedul...

journal_title：European journal of anaesthesiology

authors： Zisman E,Erport A,Kohanovsky E,Ballagulah M,Cassel A,Quitt M,Pizov R

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:While videolaryngoscopes help in the management of difficult airways, they remain too expensive for those with limited resources. We have developed a robust, re-usable, low-cost videolaryngoscope at United Mission Hospital Tansen, Nepal, by combining a smartphone-compatible endoscope capable of capturing sti...

journal_title：European journal of anaesthesiology

authors： Lambert CT,John SC,John AV

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Sedation is commonly used to facilitate diagnostic procedures in children. The aim of our study was to investigate sedation in children using propofol alone or combined with fentanyl or midazolam with regard to efficacy, adverse reactions or side-effects related to the drugs, ease of operation ...

journal_title：European journal of anaesthesiology

authors： Disma N,Astuto M,Rizzo G,Rosano G,Naso P,Aprile G,Bonanno G,Russo A

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:For more than 50 yr, uncuffed tracheal tubes have been the gold standard for intubation in children under the age of 8 yr. However, recently there has been interest in the use of cuffed tubes in paediatric practice. This survey aimed to benchmark UK practice with regard to tracheal intubation w...

journal_title：European journal of anaesthesiology

authors： Flynn PE,Black AE,Mitchell V

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We explored the effects of morphine administration during reperfusion period after an index ischaemia as well as potential molecular mechanisms underlying this response. This is of important clinical value, as morphine is used routinely in cardiovascular anaesthesia and in the emergency manage...

journal_title：European journal of anaesthesiology

authors： Mourouzis I,Saranteas T,Perimenis P,Tesseromatis C,Kostopanagiotou G,Pantos C,Cokkinos DV

更新日期：2009-07-01 00:00:00

abstract：:Quantitative assessment of myocardial ischaemia during incremental spinal, single-dose spinal and general anaesthesia may provide guidelines for the choice of anaesthetic technique for osteosynthesis of hip fractures in the elderly atherosclerotic individual. Forty-three patients with coronary artery disease were allo...

journal_title：European journal of anaesthesiology

authors： Juelsgaard P,Sand NP,Felsby S,Dalsgaard J,Jakobsen KB,Brink O,Carlsson PS,Thygesen K

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The quality of combined spinal-epidural anaesthesia mainly depends on accurate identification of the epidural space. The real-time ultrasound control of the procedure for puncture was therefore evaluated. METHODS:Thirty parturients scheduled for Caesarean section were randomized to three equal...

journal_title：European journal of anaesthesiology

authors： Grau T,Leipold RW,Fatehi S,Martin E,Motsch J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this prospective, randomized, double-blind investigation was to assess the dose-effect characteristics of postoperative nausea and vomiting after intrathecal administration of small doses of morphine (from 0.015 to 0.25 mg) in opioid-naïve, non-surgical patients. METHODS:With Ethic ...

journal_title：European journal of anaesthesiology

authors： Raffaeli W,Marconi G,Fanelli G,Taddei S,Borghi GB,Casati A

更新日期：2006-07-01 00:00:00

abstract：:In anaesthetized dogs, stellate ganglion blockade led to a moderate disturbance in left ventricular diastolic function. We investigated the effect of a left-sided block, following injection of 10 mL bupivacaine 0.5%, on echocardiographic variables of ventricular function in eight otherwise healthy patients with sympat...

journal_title：European journal of anaesthesiology

authors： Schlack W,Dinter W

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Many trauma centres have adopted the administration of fixed ratios of packed red blood cells (PRBCs), platelet concentrates and fresh frozen plasma (FFP) for bleeding patients. However, the haemostatic efficacy of this concept is not well proven. OBJECTIVE:Our objective was to characterise the haemostatic ...

journal_title：European journal of anaesthesiology

authors： Gratz J,Ponschab M,Iapichino GE,Schlimp CJ,Cadamuro J,Grottke O,Zipperle J,Oberladstätter D,Gabriel C,Ziegler B,Schöchl H

更新日期：2020-10-01 00:00:00

abstract：:A 36-year-old female presented with seizures and transient dysphasia in her 31 week of pregnancy. Neuroradiological investigations revealed a large falx meningioma. A decision was taken to deliver the infant and excise the tumor before term because of the risk of an increase in the size of the tumour and the risk of s...

journal_title：European journal of anaesthesiology

authors： Ismail K,Coakham HB,Walters FJ

更新日期：1998-01-01 00:00:00

abstract：:The post-operative period is particularly dangerous for obese patients. The aim of this study was to compare the immediate post-operative course after either laparoscopic or open gastroplasty. We studied retrospectively 20 and 14 consecutive patients who underwent laparoscopic or open adjustable silicone gastric bandi...

journal_title：European journal of anaesthesiology

authors： Juvin P,Marmuse JP,Delerme S,Lecomte P,Mantz J,Demetriou M,Desmonts JM

更新日期：1999-06-01 00:00:00

abstract：:In this review paper, the authors critically analyse the use of a number of depth of anaesthesia monitors in light of the most recent literature and their own clinical experience. There appears to be increasing evidence that anaesthesia depth monitors reduce the incidence of unexpected intraoperative awareness and als...

journal_title：European journal of anaesthesiology

authors： Bonhomme V,Hans P

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Infraclavicular plexus block has many advantages of particular interest in the emergency setting. However, the number of nerve stimulations needed to optimize the technique remains unclear. We evaluated both the local anaesthetic requirement and the success rate of Sim's derived infraclavicula...

journal_title：European journal of anaesthesiology

authors： Fuzier R,Fourcade O,Fuzier V,Albert N,Samii K,Olivier M

更新日期：2006-04-01 00:00:00