Abstract:
:In rats we studied the effects of lactoferrin on experimental acute pancreatitis caused by a single subcutaneous injection of 100 micrograms/kg body weight of caerulein. Lactoferrin isolated from human milk was given intraperitoneally to rats immediately after the injection of caerulein. The injection of 100 mg/kg body weight of lactoferrin significantly reduced the elevation of the serum amylase level and pancreatic wet weight; histological alterations of the pancreas were markedly suppressed. These results suggested that lactoferrin had a protective effect on the biochemical and histological alterations in this model.
journal_name
Digestionjournal_title
Digestionauthors
Koike D,Makino Idoi
10.1159/000201018subject
Has Abstractpub_date
1993-01-01 00:00:00pages
84-90issue
2eissn
0012-2823issn
1421-9867journal_volume
54pub_type
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