Mast cell changes in experimental diabetes: focus on attenuation of allergic events.

abstract：:The biochemical and serological characteristics, virulence properties, and genetic relatedness of Shiga toxin-producing Escherichia coli (STEC) strains isolated in S o Paulo, from April 1989 through March 1990, were determined. This is also the first report on clinic findings of human STEC infections in Brazil. The on...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Guth BE,Ramos SR,Cerqueira AM,Andrade JR,Gomes TA

更新日期：2002-12-01 00:00:00

abstract：:Visceral leishmaniasis, or kala-azar, is recognised as a serious emerging public health problem in India. In this study, environmental parameters, such as land surface temperature (LST) and renormalised difference vegetation indices (RDVI), were used to delineate the association between environmental variables and Phl...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kesari S,Bhunia GS,Chatterjee N,Kumar V,Mandal R,Das P

更新日期：2013-04-01 00:00:00

abstract：:We present herein an improved assay for detecting the presence of extracellular proteases from microorganisms on agar plates. Using different substrates (gelatin, BSA, hemoglobin) incorporated into the agar and varying the culture medium composition, we were able to detect proteolytic activities from Pseudomonas aerug...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vermelho AB,Meirelles MN,Lopes A,Petinate SD,Chaia AA,Branquinha MH

更新日期：1996-11-01 00:00:00

abstract：:In this study, IgA1 levels in the milk and serum of puerperae were compared and a correlation was established between the levels of this immunoglobulin and the occurrence of parasitism. Eighty-three paired milk and serum samples were obtained from puerperal and IgA1 levels were analyzed. In addition, the presence of i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Manhani MN,Cruz JM,Ferreira DM,Abdallah VO,Souza MA

更新日期：2008-08-01 00:00:00

abstract：:We characterized the Plasmodium falciparum antigen 332 (Ag332) which is specifically expressed during the asexual intraerythrocytic cycle of the parasite. The corresponding Pf332 gene has been located in the subtelomeric region of chromosome 11. Furthermore, it is present in all strains so far analyzed and shows marke...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mattei D,Scherf A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The time of progression towards AIDS can vary greatly among seropositive patients, and may be associated with host genetic variation. The NR1I2 (PXR) gene, a ligand-activated transcription factor, regulates the transcription immune pathway genes and can therefore be targets of viral replication mechanisms in...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Medeiros RM,Menti CF,Benelli JL,Matte MC,Melo MG,Almeida SE,Fiegenbaum M

更新日期：2017-04-01 00:00:00

abstract：:Leishmania braziliensis is the etiological agent of American mucosal leishmaniasis, one of the most severe clinical forms of leishmaniasis. Here, we report the assembly of the L. braziliensis (M2904) genome into 35 continuous chromosomes. Also, the annotation of 8395 genes is provided. The public availability of this ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： González-de la Fuente S,Camacho E,Peiró-Pastor R,Rastrojo A,Carrasco-Ramiro F,Aguado B,Requena JM

更新日期：2018-12-10 00:00:00

abstract：:Two essential oils of Lippia alba (Mill.) N.E. Brown (Verbenacea), the carvone and citral chemotypes and 15 of their compounds were evaluated to determine cytotoxicity and antifungal activity. Cytotoxicity assays for both the citral and carvone chemotypes were carried out with tetrazolium-dye, which showed a dose-depe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mesa-Arango AC,Montiel-Ramos J,Zapata B,Durán C,Betancur-Galvis L,Stashenko E

更新日期：2009-09-01 00:00:00

abstract：:The population biology of three populations of Panstrongylus megistus was compared to determine possible influence on the behaviour and epidemiological importance of this species. The results demonstrated differences in terms of egg eclosion time, nymphal mortality and development rates, and feeding and defaecation ra...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barbosa SE,Soares RP,Pires HH,Diotaiuti L

更新日期：2001-08-01 00:00:00

abstract：:Helmintex is a sensitive method used for detecting Schistosoma mansoni eggs. Here, we describe the observed frequency of six proposed criteria associated with the identification of S. mansoni eggs prepared with the Helmintex method and stained with ninhydrin. The efficacy of these criteria in classifying S. mansoni eg...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Souza RP,Favero V,Pascoal VF,Lindholz C,Bittencourt HR,Graeff-Teixeira C

更新日期：2019-01-01 00:00:00

abstract：:In this study we compared two polymerase chain reaction (PCR) methods using either 16S ribosomal RNA (rRNA) or 23S rRNA gene primers for the detection of different Leptospira interrogans serovars. The performance of these two methods was assessed using DNA extracted from bovine tissues previously inoculated with sever...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： D'Andrea A,Martinez YZ,Alduina R,Monteverde V,Molina CF,Vitale M

更新日期：2012-02-01 00:00:00

abstract：:Cytidine deaminase (MtCDA), encoded by cdd gene (Rv3315c), is the only enzyme identified in nucleotide biosynthesis pathway of Mycobacterium tuberculosis that is able to recycle cytidine and deoxycytidine. An M. tuberculosis knockout strain for cdd gene was obtained by allelic replacement. Evaluation of mRNA expressio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Villela AD,Rodrigues-Junior VS,Pinto AFM,Falcão VCA,Sánchez-Quitian ZA,Eichler P,Bizarro CV,Basso LA,Santos DS

更新日期：2017-11-01 00:00:00

abstract：:Soluble antigens (Ag) from Paracoccidioides brasiliensis, Histoplasma capsulatum and Aspergillus fumigatus were prepared and standardized by double immunodiffusion (DID) and immunoelectroosmophoresis (IEOP). No difference in sensitivity was observed between the two techniques; 100% of standard patient sera were positi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira-da-Cruz MF,Galvão-Castro B,Wanke B

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Since the early 1990s, programs to control Chagas disease in South America have focused on eradicating domiciliary Triatoma infestans, the main vector. Seroprevalence studies of the chagasic infection are included as part of the vector control programs; they are essential to assess the impact of vector contr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Russomando G,Cousiño B,Sanchez Z,Franco LX,Nara EM,Chena L,Martínez M,Galeano ME,Benitez L

更新日期：2017-05-01 00:00:00

abstract：:To assess differentiation and relationships between Anopheles lesteri and Anopheles paraliae we established three and five iso-female lines of An. lesteri from Korea and An. paraliae from Thailand, respectively. These isolines were used to investigate the genetic relationships between the two taxa by crossing experime...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Taai K,Baimai V,Saeung A,Thongsahuan S,Min GS,Otsuka Y,Park MH,Fukuda M,Somboon P,Choochote W

更新日期：2013-05-01 00:00:00

abstract：:This study aimed to evaluate well-documented diagnostic antigens, named B13, 1F8 and JL7 recombinant proteins, as potential markers of seroconversion in treated chagasic patients. Prospective study, involving 203 patients treated with benznidazole, was conducted from endemic areas of northern Argentina. Follow-up was ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Niborski LL,Grippo V,Lafón SO,Levitus G,García-Bournissen F,Ramirez JC,Burgos JM,Bisio M,Juiz NA,Ayala V,Coppede M,Herrera V,López C,Contreras A,Gómez KA,Elean JC,Mujica HD,Schijman AG,Levin MJ,Longhi SA

更新日期：2016-05-24 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) was recognised as a zoonotic pathogen in Africa and southeastern Asia. Human infections were infrequently reported until 2007, when the first known epidemic occurred in Micronesia. After 2013, the Asian lineage of ZIKV spread along the Pacific Islands and Americas, causing severe outbreaks ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Freire CCM,Palmisano G,Braconi CT,Cugola FR,Russo FB,Beltrão-Braga PC,Iamarino A,Lima Neto DF,Sall AA,Rosa-Fernandes L,Larsen MR,Zanotto PMA

更新日期：2018-05-10 00:00:00

abstract：:Project Horizonte, an open cohort of homosexual and bisexual human immunodeficiency virus (HIV-1) negative men, is a component of the AIDS Vaccine Program, in Belo Horizonte, Minas Gerais, Brazil. The objective of this study was to compare volunteers testing HIV positive at cohort entry with a sample of those who test...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Carneiro M,Cardoso FA,Greco M,Oliveira E,Andrade J,Greco DB,Antunes CM

更新日期：2003-04-01 00:00:00

abstract：:Sandfly prevalence in the Kani tribe settlements of Western Ghats in India was investigated. A total of 1,279 sandflies comprising 17 species was obtained. Sandfly abundance showed a negative correlation (r = -0.97, p = 0.003) with increase in altitudinal ranges from 0-1,000 m. When sandfly samples were grouped accord...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ranganathan S,Swaminathan S

更新日期：2015-04-01 00:00:00

abstract：:Goats from the Venezuelan northern arid zones were found infested by the following nematodes: Haemonchus contortus, Trichostrongylus axei, T. colubriformis, Cooperia curticei, Oesophagostomum columbianum, Skrjabinema ovis y Trichuris globulosa. The Shannon-Weaver index of diversity values oscillated between 0.045 and ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Morales G,Pino LA,Aldana E,Perdomo L,Molina E

更新日期：1986-04-01 00:00:00

abstract：:Sm8 is a major tegumental antigen of Schistosoma mansoni. The partial cDNA was isolated and analyzed. Sequence analysis revealed transmembrane compatible hydrophobic domains and a putative leucine zipper pattern. The mRNA and the protein are predominantly expressed in adult worms. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abath FG,Xavier EM,Montenegro SM,Werkhauser RP

更新日期：2002-01-01 00:00:00

abstract：:To analyze whether electrocardiographic alterations (ECGA) in patients with antibodies to Trypanosoma cruzi showed a pattern of familial aggregation, a sample of 379 young adults (166 men and 213 women) distributed in sibships, were assessed for the presence of anti-T. cruzi antibodies, and subjected to a complete cli...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Morini JC,Berra H,Dávila HO,Pividori JF,Bottasso OA

更新日期：1994-07-01 00:00:00

abstract：:Sixteen species of ectoparasites were collected from 50 wild rodents, from August 1990 to August 1991, in an area of Araucaria augustifolia forest, in the municipality of Tijucas do Sul, State of Paraná, Brazil. Ectoparasites infested 98% of the rodents, with the highest indices of infestation found in the drycool sea...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barros-Battesti DM,Arzua M,Linardi PM,Botelho JR,Sbalqueiro IJ

更新日期：1998-11-01 00:00:00

abstract：:This report describes the development of a SYBR Green I based real time polymerase chain reaction (PCR) protocol for detection on the ABI Prism 7000 instrument. Primers targeting the gene encoding the SSU rRNA were designed to amplify with high specificity DNA from Schistosoma mansoni, in a real time quantitative PCR ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gomes AL,Melo FL,Werkhauser RP,Abath FG

更新日期：2006-09-01 00:00:00

abstract：:The vaccine Bacillus of Calmette Guérin (BCG) was originally developed in France as an oral vaccine against tuberculosis. The oral use of this vaccine was replaced by the parenteral route in almost all countries after the Lubeck disaster. In contrast, Brazil retained the oral delivery of the vaccine until the mid-seve...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Benévolo-de-Andrade TC,Monteiro-Maia R,Cosgrove C,Castello-Branco LR

更新日期：2005-08-01 00:00:00

abstract：:This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and Plasmodium falciparum trophozoites. All of the extracts and compounds...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Claudino VD,da Silva KC,Cechinel Filho V,Yunes RA,Delle Monache F,Giménez A,Salamanca E,Gutierrez-Yapu D,Malheiros A

更新日期：2013-04-01 00:00:00

abstract：:Schistosoma mansoni was introduced in the Senegal basin around 1988, due to man-made ecological changes. Since 1991, we investigate a recent but very intense focus, Ndombo, a village near the city of Richard Toll where the outbreak was first described. Four cohorts, each a random sample (+/- 400 subjects each) from th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gryseels B,Stelma F,Talla I,Polman K,Van Dam G,Sow S,Diaw M,Sturrock RF,Decam C,Niang M

更新日期：1995-03-01 00:00:00

abstract：:A preliminary study of the pharmacokinetic parameters of t-Butylaminoethanethiol (TBAESH) was performed after administration of a single dose (35 mg/kg) either orally or intravenously. Plasma or blood samples were treated with dithiothreitol, perchloric acid and, after filtration, submitted to further purification wit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Andrade MH,Freire AC,Nelson DL

更新日期：1990-07-01 00:00:00

abstract：:Trypanosoma cruzi acute infections often go unperceived, but one third of chronically infected individuals die of Chagas disease, showing diverse manifestations affecting the heart, intestines, and nervous systems. A common denominator of pathology in Chagas disease is the minimal rejection unit, whereby parasite-free...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teixeira AR,Nascimento RJ,Sturm NR

更新日期：2006-08-01 00:00:00

abstract：:The association between pyogenic liver abscesses and schistosomiasis has been confirmed by clinical and experimental studies. In this retrospective study of 78 patients with pyogenic liver abscesses the association with schistosomiasis has been investigated. Pyodermitis, a known focus of bacteremia, was observed in 19...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teixeira R,Pfeilsticker FJ,Santa Cecília GD,Nobre V,Fonseca LP,Serufo JC,Coelho PM,Lambertucci JR

更新日期：2001-01-01 00:00:00