Cleavage of yeast tRNA(phe) with Ni(III) and Co(III) complexes of bleomycin.

abstract：:When c-Src and v-Src were immunoprecipitated together from hamster fibroblasts transformed by Rous sarcoma virus containing v-src oncogene, the total Src activity was almost threefold higher compared to c-Src activity in the control cells. The activity of v-Src immunoprecipitated separately, however, accounting for on...

journal_title：Biochemical and biophysical research communications

authors： Tuhácková Z,Vojtechová M,Hlavácek J,Ruzzene M,Sovová V,Pinna LA

更新日期：2002-01-18 00:00:00

abstract：:Dexamethasone (DEX), a potent glucocorticoid, increased the expression of T-cell death associated gene 8 (TDAG8), a proton-sensing G protein-coupled receptor, which is associated with the enhancement of acidic pH-induced cAMP accumulation, in peritoneal macrophages. We explored the role of increased TDAG8 expression i...

journal_title：Biochemical and biophysical research communications

authors： He XD,Tobo M,Mogi C,Nakakura T,Komachi M,Murata N,Takano M,Tomura H,Sato K,Okajima F

更新日期：2011-12-02 00:00:00

abstract：:Kinetics of association--dissociation, competition and chromatography on two different resins, all revealed the presence of a new binding site which: specifically accepts 7-alpha-propyl spirolactone (3H-RU-26752), has little affinity for aldosterone, is present only in the target tissue (rat kidney), and is wanting in...

journal_title：Biochemical and biophysical research communications

authors： Lazar G,Agarwal MK

更新日期：1986-01-14 00:00:00

abstract：:In isolated rat pancreatic acini, protein expression of RhoA and Rho-associated kinase, ROCK-II, and the formation of immunocomplex of RhoA with ROCK-II were enhanced by CCK-8, carbachol, and the phorbol ester TPA. The ROCK-specific inhibitor, Y-27632, did not alter basal amylase secretion, whereas it potentiated CCK-...

journal_title：Biochemical and biophysical research communications

authors： Kusama K,Nozu F,Awai T,Tanaka S,Honma I,Tsunoda Y,Mitamura K

更新日期：2003-05-30 00:00:00

abstract：:We investigated the role of the 27-kDa heat shock protein (HSP27) in cardiac protection using Langendorff-perfused rat hearts. After preconditioning (a single episode of 5 min global ischemia followed by 5 min of reperfusion), HSP27 redistributed from the cytosol to the sarcomere and recovery of the contractile functi...

journal_title：Biochemical and biophysical research communications

authors： Sakamoto K,Urushidani T,Nagao T

更新日期：2000-03-05 00:00:00

abstract：:Xanthine oxidase (XO) was found to convert nitric oxide (NO* ) released from spermine-NONOate to nitroxyl (HNO), the one-electron reduction product of NO*, in the presence of its substrate hypoxanthine under anaerobic conditions. Under these conditions, XO lost its activity. Upon aerobic incubation of XO with its subs...

journal_title：Biochemical and biophysical research communications

authors： Saleem M,Ohshima H

更新日期：2004-03-05 00:00:00

abstract：:Fructosamine-3-kinase (FN3K) and the more recently discovered fructosamine-3-kinase related protein (FN3KRP) appear to protect proteins from nonenzymatic glycation. To elucidate the patterns of transcriptional regulation of these two genes, we performed in silico comparisons of their promoters along with real-time PCR...

journal_title：Biochemical and biophysical research communications

authors： Conner JR,Beisswenger PJ,Szwergold BS

更新日期：2004-10-22 00:00:00

abstract：:Thick filaments from some striated muscles are regulated by phosphorylation of myosin regulatory light chains (RLCs). A tarantula thick filament quasi-atomic model achieved by cryo-electron microscopy has advanced our understanding on how this regulation occurs. In native thick filaments, an asymmetric intramolecular ...

journal_title：Biochemical and biophysical research communications

authors： Sulbarán G,Biasutto A,Méndez F,Pinto A,Alamo L,Padrón R

更新日期：2020-03-26 00:00:00

abstract：:Methylglyoxal (MG) (pyruvaldehyde) is an endogenous metabolite which is present in increased concentrations in diabetics and implicated in formation of advanced glycosylation end-products (AGEs) and secondary diabetic complications. Carnosine (beta-alanyl-L-histidine) is normally present in long-lived tissues at conce...

journal_title：Biochemical and biophysical research communications

authors： Hipkiss AR,Chana H

更新日期：1998-07-09 00:00:00

abstract：:The gene III protein (pIII) from phi Lf, a filamentous phage of Xanthomonas campestris pv.campestris, was purified by gel filtration with FPLC. The gIII coding region was amplified by PCR, which was then cloned into pUC18 and expressed in Escherichia coli. The size of both pIII, purified from phage particle and expres...

journal_title：Biochemical and biophysical research communications

authors： Liu TJ,You BY,Lin NT,Yang MT,Tseng YH

更新日期：1998-01-06 00:00:00

abstract：:The very long chain fatty acids (VLCFA) incorporated into plant lipids are derived from the iterative addition of C2 units provided by malonyl-CoA to an acyl-CoA by the 3-ketoacyl-CoA synthase (KCS) component of a fatty acid elongase (FAE) complex. Mining of the Arabidopsis genome sequence database revealed 20 genes w...

journal_title：Biochemical and biophysical research communications

authors： Blacklock BJ,Jaworski JG

更新日期：2006-07-28 00:00:00

abstract：:Membrane-type 1 matrix metalloproteinase (MT1-MMP) localized on the plasma membrane plays a central role in various normal biological responses including tissue remodeling, wound heeling, and angiogenesis and in cancer cell invasion and metastasis, by functioning as a collagenase and activating other matrix metallopro...

journal_title：Biochemical and biophysical research communications

authors： Miyata T,Ohnishi H,Suzuki J,Yoshikumi Y,Ohno H,Mashima H,Yasuda H,Ishijima T,Osawa H,Satoh K,Sunada K,Kita H,Yamamoto H,Sugano K

更新日期：2004-10-08 00:00:00

abstract：:Recently, the truncated TrkB receptor, T1, has been reported to be involved in the control of cell morphology via the regulation of Rho proteins, through which T1 binds Rho guanine nucleotide dissociation inhibitor (Rho GDI) 1 and dissociates it in a brain-derived neurotrophic factor (BDNF)-dependent manner. However, ...

journal_title：Biochemical and biophysical research communications

authors： Ohira K,Homma KJ,Hirai H,Nakamura S,Hayashi M

更新日期：2006-04-14 00:00:00

abstract：:The endoplasmic reticulum (ER) is an organelle in which most membrane and secretory proteins are synthesized. If these proteins are not folded correctly, unfolded proteins accumulate in the ER lumen, causing a cellular situation known as ER stress. Recently, many studies on the relationship between ER stress and disea...

journal_title：Biochemical and biophysical research communications

authors： Hosoda A,Maruyama A,Oikawa D,Oshima Y,Komachi Y,Kanai G,Sato H,Iwawaki T

更新日期：2011-02-04 00:00:00

abstract：OBJECTIVE:We have recently identified an activation site on (Na+ + K+)-ATPase and found that binding of antibody SSA412 to this specific site of the enzyme markedly augments (Na+ + K+)-ATPase catalytic activity. Demonstration of whether activation of (Na+ + K+)-ATPase affects heart function in animal in vivo was the ob...

journal_title：Biochemical and biophysical research communications

authors： Xu KY,Takimoto E,Fedarko NS

更新日期：2006-10-20 00:00:00

abstract：:Our previous studies demonstrated that intravenous administration of staphylococcal enterotoxin B (SEB) to BALB/c mice resulted in thymocyte apoptosis. In the present study, we evaluated the role of protein kinase C (PKC) in thymocyte apoptosis induced by SEB. Our results showed that the level of protein phosphorylati...

journal_title：Biochemical and biophysical research communications

authors： Lin YS,Kao SF,Jan MS,Cheng ML,Wing LY,Chang WC,Lei HY,Lin MT

更新日期：1995-08-24 00:00:00

abstract：:Kallikrein 7 (hK7), a chymostatin-like serine protease, is overexpressed in pancreatic adenocarcinomas as well as other human cancers. Although it has been demonstrated to participate in normal desquamation by facilitating cell shedding at the skin surface, its role in human malignancies remains unclear. To investigat...

journal_title：Biochemical and biophysical research communications

authors： Ramani VC,Haun RS

更新日期：2008-05-16 00:00:00

abstract：:Activity of thalamic neurons has been shown to be modulated via type-1 metabotropic glutamate receptor (mGluR1) activation, which initiates an intracellular Ca signaling cascade involving phospholipase Cbeta4 (PLCbeta4) and leading to the activation of conventional protein kinase C (cPKC). In the present study, we inv...

journal_title：Biochemical and biophysical research communications

authors： Kameyama M,Yamaguchi I,Ichikawa K,Sugiyama T,Hirono M,Hori H,Ikeda M,Kuwahata Y,Eguchi N,Urade Y,Yoshioka T

更新日期：2003-04-25 00:00:00

abstract：:Spin-trapping of superoxide ion, O2-, which is produced from two different sources (OH(-)-DMSO and xanthine-xanthine oxidase systems), was investigated by use of a water-soluble, notroso-aromatic spin trap, sodium 3,5-dibromo-4-nitrosobenzene-sulfonate (DBNBS). It was found that O2- from all sources was easily trapped...

journal_title：Biochemical and biophysical research communications

authors： Ozawa T,Hanaki A

更新日期：1986-04-29 00:00:00

abstract：:The pregnant hog ovary is a rich source of a novel exopeptidase that catalyzes the release, at pH 5.0, of collagen-related (P3-P2-P1) "triplets" such as Gly-Pro-Met, Gly-Pro-Arg, and Gly-Pro-Ala from arylamide derivatives, provided the N termini are unsubstituted. Corresponding derivatives of related (P2-P1) dipeptide...

journal_title：Biochemical and biophysical research communications

authors： McDonald JK,Hoisington AR,Eisenhauer DA

更新日期：1985-01-16 00:00:00

abstract：:While mutation of alpha-synuclein is a cause of autosomal-dominant Parkinson's disease (PD), it is still elusive as to how alpha-synuclein is involved in the pathogenesis of PD. Here, we show that dopamine-dependent accumulation of alpha-synuclein in cultured cells results in apoptosis. Furthermore, activation of insu...

journal_title：Biochemical and biophysical research communications

authors： Kao SY

更新日期：2009-07-31 00:00:00

abstract：:The present study has focused on the role of the 42- and 44-kDa mitogen-activated protein kinases (p42/44 MAPKs) and the 38-kDa mitogen-activated protein kinase (p38 MAPK) in the proliferation of the pancreatic beta-cell line MIN6. MIN6 beta-cell proliferation was assessed by measuring 5-bromo-2'-deoxyuridine (BrdU) i...

journal_title：Biochemical and biophysical research communications

authors： Burns CJ,Squires PE,Persaud SJ

更新日期：2000-02-16 00:00:00

abstract：:We present here further evidence supporting that histone H1 contains a nucleotide binding site interacting e.g. with ADP, ATP, GDP and GTP. The finding is in accordance with the previous observation that nucleotides modulate recognition of DNA by H1. Most interestingly, H1 appears to be capable of hydrolyzing NTPs and...

journal_title：Biochemical and biophysical research communications

authors： Mannermaa RM,Oikarinen J

更新日期：1992-01-15 00:00:00

abstract：:The 3' untranslated region (UTR) of the hepatitis C virus (HCV) is believed to function in the initiation and regulation of viral RNA replication and protein translation by interacting with the viral and host components. To examine host proteins interacting with the HCV 3'UTR, biotinylated 3'(+)UTR, and its reverse co...

journal_title：Biochemical and biophysical research communications

authors： Tingting P,Caiyun F,Zhigang Y,Pengyuan Y,Zhenghong Y

更新日期：2006-09-01 00:00:00

abstract：:We previously described the identification of the 3'end of an unknown gene CDK7 using differential display which appeared to be up-regulated in diabetic kidneys [R.A. Page, C.A. Morris, J.D. Williams, C.J. von Ruhland, A.N. Malik, Isolation of diabetes-associated kidney genes using differential display, Biochem. Bioph...

journal_title：Biochemical and biophysical research communications

authors： Malik AN,Rossios C,Al-Kafaji G,Shah A,Page RA

更新日期：2007-05-25 00:00:00

abstract：:Examination of human follicular fluid revealed the presence of polychlorinated dibenzodioxins (PCDDs) and dibenzofurans (PCDFs) at concentrations of approximately 1 pg/ml (0.01 pg TEQ/ml). To study their possible action, two-cell mouse embryos were cultured in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)...

journal_title：Biochemical and biophysical research communications

authors： Tsutsumi O,Uechi H,Sone H,Yonemoto J,Takai Y,Momoeda M,Tohyama C,Hashimoto S,Morita M,Taketani Y

更新日期：1998-09-18 00:00:00

abstract：:A murine interferon gene (MuIFN alpha) has been isolated from a cosmid library. The sequence of a 1.2-kb HindIII-PstI fragment revealed a new MuIFN alpha gene which has not yet been described and which was termed MuIFN alpha 7. The coding sequence produced biologically active IFN when expressed in monkey cells under t...

journal_title：Biochemical and biophysical research communications

authors： Dion M,Vodjdani G,Doly J

更新日期：1986-07-31 00:00:00

abstract：:In T lymphocyte, activation of Kv1.3 channel, the major voltage-dependent K(+) channel, is an essential step for cell proliferation in immune responses. Here, effects of anti-CD3 and anti-CD28 antibodies on Kv1.3 current were examined in three types of human T lymphocyte derived cell lines, Jurkat E6-1, p56lck-kinase ...

journal_title：Biochemical and biophysical research communications

authors： Matsushita Y,Ohya S,Itoda H,Kimura T,Suzuki Y,Yamamura H,Imaizumi Y

更新日期：2008-09-12 00:00:00

abstract：:Quercetin is one of the most prominent dietary antioxidants. During its antioxidant activity, quercetin becomes oxidized into its o-quinone/quinone methide QQ. QQ is toxic since it instantaneously reacts with thiols of, e.g., proteins. In cells, QQ will initially form an adduct with glutathione (GSH), giving GSQ. We h...

journal_title：Biochemical and biophysical research communications

authors： Boots AW,Balk JM,Bast A,Haenen GR

更新日期：2005-12-16 00:00:00

abstract：:The IGF/IGF-1R system, which includes the IGF, IGF-1R, and IGFBPs proteins, plays an important role in the development and growth of colorectal cancer. We previously reported that in the HT29 human colon cancer cell line EGCG, the major biologically active component of green tea, inhibits activation of the RTKs EGFR, ...

journal_title：Biochemical and biophysical research communications

authors： Shimizu M,Deguchi A,Hara Y,Moriwaki H,Weinstein IB

更新日期：2005-09-02 00:00:00