Abstract:
:5-(Hydroxymethyl)uracil, 5-formyluracil or 5-carboxyuracil can be formed in DNA upon exposure to ionizing radiations. We report the effect of the latter oxidative lesions on the in vitro transcription by T7 RNA polymerase using a single-stranded short model template. Kinetic experiments showed that the transcription yield was increased with the modified template. Due to the unforeseen presence of a hairpin structure within the transcribed RNA, we postulated that we are in the presence of a T7 RNA polymerase pausing signal and that the lesions within this critical DNA structure could interfere with normal regulation of RNA transcription.
journal_name
C R Bioljournal_title
Comptes rendus biologiesauthors
Guerniou V,Gasparutto D,Douki T,Cadet J,Sauvaigo Sdoi
10.1016/j.crvi.2005.07.003subject
Has Abstractpub_date
2005-09-01 00:00:00pages
794-801issue
9eissn
1631-0691issn
1768-3238pii
S1631-0691(05)00130-7journal_volume
328pub_type
杂志文章abstract::The evolutionary history of modern humans means much more than their demographic past. It includes the way in which humans have had to genetically adapt to the different environments they have encountered-nutritional, climatic or pathogenic-as well as the different epigenetic responses elicited by such environmental c...
journal_title:Comptes rendus biologies
pub_type: 杂志文章,评审
doi:10.1016/j.crvi.2016.04.005
更新日期:2016-07-01 00:00:00
abstract::Hardwood trees are able to reorient their axes owing to tension wood differentiation. Tension wood is characterised by important ultrastructural modifications, such as the occurrence in a number of species, of an extra secondary wall layer, named gelatinous layer or G-layer, mainly constituted of cellulose microfibril...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2004.07.006
更新日期:2004-09-01 00:00:00
abstract::The green birdmouth wrasse Gomphosus caeruleus is present all year round on the coral reefs of Reunion Island (Indian Ocean). A group of individuals was followed on one of these reefs with the objective of studying the reproduction mode of the species, the influence of environmental factors, and social behaviors on th...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2017.11.004
更新日期:2018-01-01 00:00:00
abstract::Only females were observed in Spasalus crenatus (Mac Leay 1819) in the Antilles, from Puerto Rico to Saint-Vincent, whereas both sexes are in Trinidad and on the continent. No difference in endo- and ectodermic female genitalia could be noticed between the two populations. Chromosomes of specimens from Guadeloupe reve...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2015.09.001
更新日期:2015-11-01 00:00:00
abstract::We test relationships between structure of acoustic signal used for individual recognition and nesting ecology among two gulls: the black-headed gull (Larus ridibundus), in which chicks remain in the nest, and the slender-billed gull (L. genei), in which chicks leave the nest after hatching to form crèches. A striking...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/s1631-0691(03)00072-6
更新日期:2003-03-01 00:00:00
abstract::Austronesians colonized the islands of Rapa Nui, Hawaii, the Marquesas and Madagascar. All of these islands have been found to harbor Austronesian artifacts and also, all of them are known nesting sites for marine turtles. Turtles are well known for their transoceanic migrations, sometimes totalling thousands of miles...
journal_title:Comptes rendus biologies
pub_type: 历史文章,杂志文章
doi:10.1016/j.crvi.2015.12.001
更新日期:2016-02-01 00:00:00
abstract::The effect of Phragmanthera capitata (Sprengel) Balle, an epiphytic Loranthaceae, on latex production of three clones of rubber tree, Hevea brasiliensis (Müll. Arg.), was studied in the industrial plantation of Mitzic, in Gabon. The 22-year-old trees, presenting the largest trunk circumference, were the most parasitiz...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2006.01.007
更新日期:2006-03-01 00:00:00
abstract::Two ground-dwelling couas species, Coquerel's Coua Coua coquereli and Giant Coua Coua gigas, live in sympatry in the dry forest of Madagascar. These birds are typically insectivorous and mainly feed at ground level. The two species differ by size but have the same morphology, suggesting they have the same physical att...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2009.01.005
更新日期:2009-06-01 00:00:00
abstract::Plectroctena minor workers have long mandibles that can snap and deliver a sharp blow to intruders or prey, stunning or killing them. Encounters between homocolonial P. minor workers separated for 24 h or 15 days never resulted in snapping, while this behaviour was always noted during encounters between heterocolonial...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/s1631-0691(02)01484-1
更新日期:2002-07-01 00:00:00
abstract::Aphids are among the few organisms capable of reproducing either sexually or asexually. This plasticity in reproductive mode is viewed as an adaptive response to cope with seasonal changes. Clonal reproduction occurs during the growing season allowing rapid population increase, while sexual reproduction occurs during ...
journal_title:Comptes rendus biologies
pub_type: 杂志文章,评审
doi:10.1016/j.crvi.2010.03.003
更新日期:2010-06-01 00:00:00
abstract::Why was sexual selection so important to Darwin? And why was it de-emphasized by almost all of Darwin's followers until the second half of the 20th century? These two questions shed light on the complexity of the scientific tradition named "Darwinism". Darwin's interest in sexual selection was almost as old as his dis...
journal_title:Comptes rendus biologies
pub_type: 传,历史文章,杂志文章
doi:10.1016/j.crvi.2009.12.001
更新日期:2010-02-01 00:00:00
abstract::The genus Pseudouroplectes Lourenço, 1995 (Buthidae) remains among the less speciose Malagasy genera and all the known species are extremely rare. A new species is described from the dry forests in the Tsingy formations of the National Park Bemaraha, extending the distribution of the genus further north. Once again, t...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2015.11.001
更新日期:2016-01-01 00:00:00
abstract::Nonessential metal cadmium is widely used and released in the environment, causing cell toxicity and posing a severe threat to wildlife. Zebrafish (Danio rerio) is one of the most commonly used animals in the investigation of environmental cadmium toxicity in vertebrates. In this study, we identified two cadmium-respo...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2017.03.004
更新日期:2017-04-01 00:00:00
abstract::To add to our understanding of dendrocoelid spermatozoa and to describe additional phylogenetic characters, the ultrastructure of the testis was investigated in the subterranean freshwater planarian Dendrocoelum constrictum. This is the first study investigating spermatogenesis and spermatozoon ultrastructure in a sub...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2014.07.004
更新日期:2014-09-01 00:00:00
abstract::Exploiting the annotation of the western clawed frog Silurana tropicalis genome, we identified a new metallothionein (MT) gene, exhibiting all the features to be considered an active gene, but with an atypical coding region, showing only 17 cysteine residues instead of the canonical 20 cysteines of vertebrate metallot...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2015.03.011
更新日期:2015-05-01 00:00:00
abstract::Rhizomania is one of serious threat to sugar beet production in Morocco and in several parts of the world. This disease led to a statistically significant decrease in the quality and yield of sugar beet plantations. Therefore, this study aimed at comparing the efficacy of six commonly used RNA extraction methods for t...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2018.06.003
更新日期:2018-01-01 00:00:00
abstract::Bacterial blight (BB) is caused by Xanthomonas oryzae pv. oryzae (Xoo), a most destructive disease of rice, mostly in Asia, including Bangladesh. Altogether 96 isolates of Xoo were collected from 19 rice-growing districts of Bangladesh in both the rain-fed and irrigated seasons of 2014 to assess their pathotypic and g...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2016.06.002
更新日期:2016-09-01 00:00:00
abstract::Although there are many types of epilepsy of both genetic and acquired forms, temporal lobe epilepsy (TLE) with hippocampal sclerosis is probably the single most common human epilepsy, and the one most intensely studied. Despite a wealth of descriptive data obtained from patient histories, imaging techniques, electroe...
journal_title:Comptes rendus biologies
pub_type: 杂志文章,评审
doi:10.1016/j.crvi.2004.10.010
更新日期:2005-02-01 00:00:00
abstract::This note presents a mechanistic explanation of the transition between the morphology of cephalochordates to that of amniotes. By a careful study of the morphogenetic movements which occur during the early stages of development of a typical amniote (a chicken embryo), we are able to show that the formation of a verteb...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2010.11.009
更新日期:2011-02-01 00:00:00
abstract::This article presents the floristic, structural, and syntaxonomical features of plant assemblages in temporary wetlands and the pattern of the corresponding habitat types; according to the Habitats Directive. Nine pristine temporary wetlands covering a wide range of shapes, elevations and substrates were monitored. Th...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2010.06.006
更新日期:2010-09-01 00:00:00
abstract::Cattle, sheep and goats were domesticated about 10,000 years ago, spread out of the domestication centers in Europe, Asia, and Africa during the next few thousands years, and gave many populations locally adapted. After a very long period of soft selection, the situation changed dramatically 200 years ago with the eme...
journal_title:Comptes rendus biologies
pub_type: 杂志文章,评审
doi:10.1016/j.crvi.2010.12.007
更新日期:2011-03-01 00:00:00
abstract::Domestication is the process of organism evolution under selection by humans, and as such has been a model for studying adaptation since Charles Darwin. Here we review recent studies on the genomics of adaptation and domestication syndrome in two cheese-making fungal lineages, Penicillium roqueforti used for maturing ...
journal_title:Comptes rendus biologies
pub_type: 杂志文章,评审
doi:10.5802/crbiol.15
更新日期:2020-10-09 00:00:00
abstract::Eutypa dieback (dying arm disease, eutypiosis) is a very devastating disease in many grape-producing areas around the world. This vascular disease is induced by the ascomycete Eutypa lata Pers. Fr. Tul & C. Tul. invading the trunk by pruning wounds. The environmental factors and the nutritional requirements regulating...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2005.01.006
更新日期:2005-03-01 00:00:00
abstract::Using protein loci and DNA markers, we show by a multilocus genetic analysis that certain populations of the two sympatric mouse species Mus musculus domesticus and Mus spretus show clear signs of partial introgression. Given the sterility of F1 males and the known partial genetic incompatibilities between the genomes...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/s1631-0691(02)01413-0
更新日期:2002-02-01 00:00:00
abstract::Few proteins have had such a strong impact on a field as the lac repressor has had in Molecular Biology. Over 40 years ago, Jacob and Monod [Genetic regulatory mechanisms in the synthesis of proteins, J. Mol. Biol. 3 (1961) 318] proposed a model for gene regulation, which survives essentially unchanged in contemporary...
journal_title:Comptes rendus biologies
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.crvi.2005.04.004
更新日期:2005-06-01 00:00:00
abstract::Alloscorpiops (Laoscorpiops) calmonti subgen. n., sp. n., belonging to the family Euscorpiidae Laurie, is described on the basis of single female specimen collected in the Pathoumphone District of southern Laos. This new scorpion taxon may represent yet another endemic element for the fauna of Laos. The new subgenus i...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2013.01.001
更新日期:2013-01-01 00:00:00
abstract::Male infertility is the cause in half of all childless partnerships. Numerous factors contribute to male infertility, including chromosomal aberrations and gene defects. Few data exist regarding the association of these chromosomal aberrations with male infertility in Arab and North African populations. We therefore a...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2014.02.006
更新日期:2014-04-01 00:00:00
abstract::An efficient method of regeneration for antidiabetic plant (Stevia rebaudiana) has been established for healthy biomass and main steviol glycosides (SGs) production, using different PGRs and agar concentrations. Higher callus induction (93.3%) was recorded when leaf explants were placed on an MS medium supplemented wi...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2013.10.002
更新日期:2013-10-01 00:00:00
abstract::To determine if a type of unicoloniality exists in the fire ant Solenopsis saevissima in its native range, we conducted intraspecific aggressiveness tests in French Guiana between workers originating from 15 human-disturbed sites. We identified two "colonial groups" spread over 54 km and 12.5 km, respectively. Workers...
journal_title:Comptes rendus biologies
pub_type: 杂志文章
doi:10.1016/j.crvi.2011.01.007
更新日期:2011-04-01 00:00:00
abstract::Two aspects of psychology and physiology of time are dealt with in this paper: the way time perception was increasingly studied during the 19th century by scientists, including many physicists, and the way the temporal properties of the nervous system were discovered and explored by physiologists. The neurophysiologic...
journal_title:Comptes rendus biologies
pub_type: 历史文章,杂志文章
doi:10.1016/j.crvi.2006.03.004
更新日期:2006-05-01 00:00:00