当前位置： SCI文献检索 > PHYSIOLOGY & BEHAVIOR期刊下所有文献 > GABA receptor agonists in the medial preoptic area and maternal behavior in lactating rats.

GABA receptor agonists in the medial preoptic area and maternal behavior in lactating rats.

Abstract：

:We studied the effects of injecting agonists of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) muscimol (GABA-A receptor agonist) and baclofen (GABA-B receptor agonist) in the medial preoptic area (MPOA) and neighboring brain regions, the bed nucleus of the stria terminalis (BNST), and lateral preoptic area (LPO) on maternal behavior. Lactating female rats were implanted with bilateral cannulae in the MPOA/BNST on day 1 postpartum. On day 5, a maternal behavior test was conducted in the home cage after females received injections of muscimol or baclofen (0, 12.5, 50 or 200 ng per side). On day 7, after MPOA/BNST injections, a second maternal behavior test was conducted with pups placed at the end of a T-runway projecting from the home cage. Finally, after injections on day 9 maternal aggression, olfaction, and locomotor behavior were tested. The GABA receptor agonists injected in the MPOA/BNST produced dose-dependent deficits in all components of maternal behavior, including maternal aggression, except licking. Muscimol produced deficits in the active component, nest building at lower doses than baclofen, both agonists produced deficits in retrieving, while baclofen produced deficits in passive components (hovering and crouching over pups) at lower doses than muscimol. Both GABA receptor agonists increased locomotor activity and reduced olfactory responsiveness but these were only correlated with deficits in retrieving and crouching in baclofen-treated females.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Arrati PG,Carmona C,Dominguez G,Beyer C,Rosenblatt JS

doi

10.1016/j.physbeh.2005.08.048

subject

Has Abstract

pub_date

2006-01-30 00:00:00

pages

51-65

issue

1

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(05)00376-8

journal_volume

87

pub_type

杂志文章

相关文献

PHYSIOLOGY & BEHAVIOR文献大全
  • Air righting: role of the NMDA receptor channel and hippocampal LTP.

    abstract：:Air righting results in an animal turning over when it is dropped from a height in an inverted position. In the rat, air righting is a complex set of movements that depends only on an intact labyrinth and the normal vestibular input. Visual modulation of air righting does not develop until adulthood; and the ability t...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/s0031-9384(00)00208-0

    authors： Wayner MJ,Tracy HA,Armstrong DL,Phelix CF

    更新日期：2000-06-01 00:00:00

  • A simple device for experimentally concussing the rat.

    abstract：:A device is described for eliciting acceleration concussion in the awake rat. Animals, which were manually restrained, were struck on the occipital crest by a rubber knob attached to the striker wire of a spring-loaded rat trap. This method produced concussion with survival in over 50% of animals tested. The remainder...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(85)90154-4

    authors： Shaw NA

    更新日期：1985-10-01 00:00:00

  • Mindfulness training disrupts Pavlovian conditioning.

    abstract：:Classical conditioning is a quintessential learning process; however, maladaptive forms of conditioning sustain many unhealthy behaviors (e.g., addiction). Mindfulness training is theorized to de-automatize conditioned behavior by decoupling stimulus and response. This study assessed the effect of mindfulness training...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2019.02.028

    authors： Hanley AW,Garland EL

    更新日期：2019-05-15 00:00:00

  • Repeated cocaine treatment activates flank marking in adolescent female hamsters.

    abstract：:Cocaine abuse during adolescence represents a significant health risk due to the potential for both acute and long-term negative physical and psychological sequelae, including increased aggressive behavior. This study examined the effect of adolescent cocaine treatment on flank marking (i.e., a stereotypic motor behav...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/s0031-9384(01)00478-4

    authors： Melloni RH Jr,Connor DF,Todtenkopf MS,DeLeon KR,Sanyal P,Harrison RJ

    更新日期：2001-07-01 00:00:00

  • There is no sweet escape from social pain: glucose does not attenuate the effects of ostracism.

    abstract：:Ostracism causes social pain and is known to activate regions of the brain that are involved in the representation of physical pain. Previous research has observed that acetominophen (a common pain reliever) can reduce the pain of exclusion. The taste and consumption of glucose can also relieve physical pain, and the ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.physbeh.2013.10.032

    authors： Miller HC,Bourrasseau C,Williams KD,Molet M

    更新日期：2014-01-30 00:00:00

  • Water deprivation produces an exercise-induced weight loss phenomenon in the rat.

    abstract：:Rats given restricted feeding and allowed free access to activity wheels increase activity, decrease food intake, and lose body weight compared to nonexercised controls. The phenomenon is of interest because of the relationship between exercise and anorexia nervosa. This study determined if another factor that energiz...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(93)90161-8

    authors： Rieg TS,Doerries LE,O'Shea JG,Aravich PF

    更新日期：1993-03-01 00:00:00

  • Animal models for the study of the effect of prolonged stress on lactation in rats.

    abstract：:The suppressive effect of stress on lactation is well acknowledged. Animal models used to study this problem have used primarily acute stressors. As such, they are not adequate for the study of the effect of prolonged stress on lactation. This study aimed at developing a paradigm(s) in rats for the study of the effect...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2004.05.004

    authors： Lau C,Simpson C

    更新日期：2004-09-15 00:00:00

  • Conditioned avoidance behavior in pretrained rats intermittently treated with addictive drugs.

    abstract：:Rats pretrained in a conditioned avoidance (CAR) paradigm were put on eight potentially addictive drugs in drinking water at two dose levels each. Fluid intake and body weight, monitored during the drugged (addiction) and nondrugged (withdrawal) states, showed drug/dose-dependent fluctuations in most groups. Extinctio...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(75)90103-1

    authors： Banerjee U

    更新日期：1975-09-01 00:00:00

  • Scent-marking and sexual activity may reflect social hierarchy among group-living male Mongolian gerbils (Meriones unguiculatus).

    abstract：:Social hierarchy plays an important role in the lives of gregarious species. We investigated how social hierarchy between male Mongolian gerbils (Meriones unguiculatus) housed together before sexual maturity affected their scent-marking behavior, endocrine status and physical traits as adults. The social rank between ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2006.08.001

    authors： Shimozuru M,Kikusui T,Takeuchi Y,Mori Y

    更新日期：2006-12-30 00:00:00

  • Mate choice could be random in female rats (Rattus norvegicus).

    abstract：:Female mate choice is often investigated in terms of reproductive success in order to understand how male characteristics contribute to sexual attractiveness. Previous studies have found that females rats prefer mating with their first encounter rather than males visited subsequently, suggesting that the rewarding val...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2017.10.031

    authors： Le Moëne O,Snoeren EM

    更新日期：2018-02-01 00:00:00

  • Placental and fetal growth restriction, size at birth and neonatal growth alter cognitive function and behaviour in sheep in an age- and sex-specific manner.

    abstract：:Intrauterine growth restriction and slow neonatal growth in humans are each associated with poorer learning, memory and cognitive flexibility in childhood and adulthood. The relative contributions of pre- and post-natal growth to cognitive outcomes are unclear, however. We therefore compared performance in learning, m...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2015.08.042

    authors： Hunter DS,Hazel SJ,Kind KL,Liu H,Marini D,Giles LC,De Blasio MJ,Owens JA,Pitcher JB,Gatford KL

    更新日期：2015-12-01 00:00:00

  • Metabolic responses to intracerebroventricular leptin and restricted feeding.

    abstract：:Leptin is a hormone secreted by adipocytes, which plays an important role in the control of food intake and metabolic processes. In the current study, a dose-dependent relationship was shown between a bolus intracerebroventricular rat recombinant leptin administration and reductions in food intake and body weight in S...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/s0031-9384(98)00243-1

    authors： Wang T,Hartzell DL,Rose BS,Flatt WP,Hulsey MG,Menon NK,Makula RA,Baile CA

    更新日期：1999-01-01 00:00:00

  • Schisantherin A recovers Aβ-induced neurodegeneration with cognitive decline in mice.

    abstract：:Schisantherin A (STA) is a main bioactive lignan isolated from Schisandra chinensis (Turcz.) Baill., which has been widely used as a tonic in traditional Chinese medicine for many years. Lots of studies have reported that STA exhibited anti-inflammatory and antioxidant effects. This paper was designed to investigate t...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2014.04.046

    authors： Li X,Zhao X,Xu X,Mao X,Liu Z,Li H,Guo L,Bi K,Jia Y

    更新日期：2014-06-10 00:00:00

  • Effect of diet upon ventilation and effort perception during a physical stressor.

    abstract：:The present research explored the effects of a high and low carbohydrate diet on ratings of perceived exertion (RPE) during a 10 minute bicycle ergometer test at high physical work capacity (70% of maximum aerobic capacity). Twelve female student volunteers participated and were randomly assigned the order of diet tre...

    journal_title：Physiology & behavior

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0031-9384(85)90140-4

    authors： Demeersman R,Schaefer DC,Miller WW

    更新日期：1985-10-01 00:00:00

  • REM sleep deprivation affects extinction of cued but not contextual fear conditioning.

    abstract：:Previous research has demonstrated that rapid eye movement (REM), or paradoxical, sleep deprivation can interfere with the retention of certain types of learning tasks, particularly spatial learning. The present study investigated the effects of 6 h of REM sleep deprivation on the retention and extinction of both cued...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2004.11.011

    authors： Silvestri AJ

    更新日期：2005-03-16 00:00:00

  • Food marketing to children in the United States: Can industry voluntarily do the right thing for children's health?

    abstract：:Food marketing is a major contributor to high rates of obesity and diet-related disease among children. Researchers, advocates, and policymakers have called for improvements in the nutrition quality of foods marketed to children to improve children's health. In the United States, for over 10 years, the food and bevera...

    journal_title：Physiology & behavior

    pub_type： 杂志文章,评审

    doi：10.1016/j.physbeh.2020.113139

    authors： Fleming-Milici F,Harris JL

    更新日期：2020-12-01 00:00:00

  • Effects of single and repeated restraint on the social behavior of male rats.

    abstract：:The effects of a mild, nonpainful stressor (restraint, RT) on the social behavior of male rats were explored. Twenty-four hours after single or repeated RT, experimental subjects were confronted in a neutral cage with unfamiliar and naive opponents of the same sex and strain, matched for age and body weight. Introduct...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(93)90272-h

    authors： Albonetti ME,Farabollini F

    更新日期：1993-05-01 00:00:00

  • Effects of repeated stress on plasma arginine levels in young and old rats.

    abstract：:The effect of age and recurring stress responses on endogenous plasma arginine (ARG) concentrations were determined. Blood from catheterized young (3 months) and old (24 months) were used to ascertain the plasma concentrations of ARG under baseline conditions, during a 30-min immobilization experience and during a 3.5...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(93)90083-r

    authors： Milakofsky L,Harris N,Vogel WH

    更新日期：1993-10-01 00:00:00

  • Effect of brain lesions on rat shuttle behavior in four different tests.

    abstract：:Rats were trained to perform shuttle responses to a buzzer in four different situations: pseudoconditioning or D test (buzzers and footshocks presented at random), classical conditioning or DP test (buzzers and footshocks paired on every trial), avoidance without stimulus pairing or DC test (buzzer-shock intervals var...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(79)90128-8

    authors： Schütz RA,Izquierdo I

    更新日期：1979-07-01 00:00:00

  • Acute effects of light and darkness on the activity and temperature rhythms of a subterranean rodent, the Anillaco tuco-tuco.

    abstract：:Tuco-tucos from Anillaco (Ctenomys aff. knighti), are subterranean rodents that run vigorously on laboratory wheels during the night but are active during the day in semi-natural enclosures, where they surface for foraging and burrow maintenance, under intense sunlight. Several studies have shown that light causes opp...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2019.112645

    authors： Yassumoto TI,Tachinardi P,Oda GA,Valentinuzzi VS

    更新日期：2019-10-15 00:00:00

  • Beta-thioglucose inhibits gold thioglucose lesions in the ventromedial hypothalamus.

    abstract：:Gold thioglucose (GTG) has been known to be an obesity causing agent for over 40 years. GTG works by affecting dendrites in the mouse ventromedial hypothalamus (VMH) producing a permanent VMH lesion and subsequent hyperphagia and obesity. We have investigated the effect of beta-thioglucose (BTG), a glucose antimetabol...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(89)90005-x

    authors： Brown DF,McGuirk JP,Larsen SP,Minter SD

    更新日期：1989-09-01 00:00:00

  • Sexual experience with a known male modulates c-Fos expression in response to mating and male pheromone exposure in female mice.

    abstract：:Sexually naïve female mice are not sexually receptive in their first mating opportunity. Four to five sexual encounters are needed to display high sexual receptivity as assessed by the lordosis reflex. The neuronal changes induced by sexual experience are not well understood. In this study, we evaluated if repeated se...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2020.112906

    authors： Marco-Manclus P,Paredes RG,Portillo W

    更新日期：2020-08-01 00:00:00

  • Effects of postweaning undernutrition on exploratory behavior, memory and sensory reactivity in rats: implication of the dopaminergic system.

    abstract：:The effects of early undernutrition on behavior and brain biochemistry were examined in rats. At weaning, rats were provided either an ad lib diet (control group) or maintained at 80% of the weight of their control littermates (undernourished group). Three weeks into the diet they were tested in an open field. After 6...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2005.07.008

    authors： Alamy M,Errami M,Taghzouti K,Saddiki-Traki F,Bengelloun WA

    更新日期：2005-09-15 00:00:00

  • Plasma catecholamine responses during a personalized physical stress as a dynamic characterization of essential hypertension.

    abstract：:High performance liquid chromatography (HPLC) with electrochemical detection proves to be a reliable method for determination of plasma catecholamines (CA) to assess the possible role of the sympathetic nervous system (SNS) in essential hypertension (EH). The present investigation in a group of 15 normotensive (N) and...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(91)90302-5

    authors： Tosti-Croce C,Lucarelli C,Betto P,Floridi A,Rinaldi R,Salvati A,Taggi F,Sciarra F

    更新日期：1991-04-01 00:00:00

  • Visual unit, EEG and sustained potential shift responses in the brains of toads (Bufo bufo) during alert and defensive behavior.

    abstract：:Cranially mounted differential preamplifiers allowed visual unit activity, EEGs and sustained potential shifts to be monitored from the tectum of freely moving toads (Bufo bufo). Alert behavior was elicited by a moving visual stimulus. Movement of the stimulus in the receptive field of a unit elicited its activity and...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(84)90264-6

    authors： Laming PR,Borchers HW,Ewert JP

    更新日期：1984-03-01 00:00:00

  • Gustatory reaction time under variable stimulus parameters in human adults.

    abstract：:Reaction times and perceived intensities for NaCl solutions were measured in sixteen human adults. Stimulus delivery was by means of a circular piece of solution-soaked filter paper held with forceps. The reaction time (T) decreased and the perceived intensity (S) increased with increasing the concentration (C) of NaC...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(82)90369-9

    authors： Yamamoto T,Kato T,Matsuo R,Araie N,Azuma S,Kawamura Y

    更新日期：1982-07-01 00:00:00

  • Cold water stress analgesia in rats: differential effects of naltrexone.

    abstract：:Cold water swim (CWS, 2 degrees C, 3.5 min) decreases the responsiveness to nociceptive stimuli in rats. The influence of various parameters of the CWS condition on stress-induced analgesia were evaluated by means of naltrexone effects. Naltrexone dose-dependently (but significantly only at high doses--21 mg/kg) parti...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(84)90308-1

    authors： Girardot MN,Holloway FA

    更新日期：1984-04-01 00:00:00

  • The effects of long-term isolation on physiology and behavior in male guinea pigs.

    abstract：:Studied were isolation induced effects in guinea pigs. Males (CM) living in two colonies (12 males, 12 females, each) were compared to males (IM) born in the colonies and kept isolated from their 2nd month of age. The findings were: At 19 months of age CM showed higher testosterone and cortisol titers, higher adrenal ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(86)90129-0

    authors： Sachser N

    更新日期：1986-01-01 00:00:00

  • Magnetic field effects on pineal N-acetyltransferase activity and melatonin content in the gerbil--role of pigmentation and sex.

    abstract：:The ambient geomagnetic field influences a variety of biological phenomena. Electrical and biochemical parameters of the rodent pineal gland are influenced by the alteration of weak magnetic fields (MF), the magnetic receptor probably residing in the retina. However, open questions concern the role of retinal pigmenta...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(88)90350-2

    authors： Stehle J,Reuss S,Schröder H,Henschel M,Vollrath L

    更新日期：1988-01-01 00:00:00

  • Chronic salt-loading reduces basal excitatory input to CRH neurons in the paraventricular nucleus and accelerates recovery from restraint stress in male mice.

    abstract：:Neurons synthesizing corticotrophin-releasing hormone (CRH) in the paraventricular nucleus of the hypothalamus (PVN) are activated during acute stress and act via the hypothalamic-pituitary-adrenal (HPA) axis to increase systemic levels of corticosterone (CORT). Recent data indicates that CRH neurons in the PVN are in...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2017.03.038

    authors： Krause EG,Pati D,Frazier CJ

    更新日期：2017-07-01 00:00:00