Surgical alternatives to the Fontan procedure incorporating a hypoplastic right ventricle.

abstract：BACKGROUND:Regional sympathetic denervation, such as that produced by a myocardial infarction, causes electrophysiological heterogeneity in the ventricles. The purpose of this study was to test the hypothesis that such denervation could cause drugs to exert heterogeneous myocardial effects. METHODS AND RESULTS:Sympath...

journal_title：Circulation

authors： Stanton MS,Zipes DP

更新日期：1991-10-01 00:00:00

abstract：:Mapping of blood velocities across the lumen of the ascending aorta was performed in eight patients during open-heart surgery. A Doppler ultrasound probe was constructed to measure velocities in 2 mm steps from the maximum convexity to the maximum concavity of aorta, 6 to 7 cm above the aortic valve. In five patients ...

journal_title：Circulation

authors： Segadal L,Matre K

更新日期：1987-07-01 00:00:00

abstract：:To compare angiographically-determined coronary artery disease in diabetic patients with controls, 1,653 patients coming to cardiac catheterization were reviewed retrospectively to find 37 diabetic and 79 control patients matched for sex, age (+/- 3 years), and risk factors (hypertension, hyperlipidemia, and smoking)....

journal_title：Circulation

authors： Dortimer AC,Shenoy PN,Shiroff RA,Leaman DM,Babb JD,Liedtke AJ,Zelis R

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Calcineurin is a calcium-regulated phosphatase that plays a major role in cardiac hypertrophy. We previously described that alternative splicing of the calcineurin Aβ (CnAβ) gene generates the CnAβ1 isoform, with a unique C-terminal region that is different from the autoinhibitory domain present in all other...

journal_title：Circulation

authors： Felkin LE,Narita T,Germack R,Shintani Y,Takahashi K,Sarathchandra P,López-Olañeta MM,Gómez-Salinero JM,Suzuki K,Barton PJ,Rosenthal N,Lara-Pezzi E

更新日期：2011-06-21 00:00:00

abstract：BACKGROUND:Long-term comparative data of first-generation drug-eluting stents are scarce. We investigated clinical and angiographic outcomes of sirolimus-eluting (SES) and paclitaxel-eluting stents (PES) at 5 years as part of the Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization (SIRTAX)...

journal_title：Circulation

authors： Räber L,Wohlwend L,Wigger M,Togni M,Wandel S,Wenaweser P,Cook S,Moschovitis A,Vogel R,Kalesan B,Seiler C,Eberli F,Lüscher TF,Meier B,Jüni P,Windecker S

更新日期：2011-06-21 00:00:00

abstract：BACKGROUND:Hutchinson-Gilford progeria syndrome is an ultrarare segmental premature aging disease resulting in early death from heart attack or stroke. There is no approved treatment, but starting in 2007, several recent single-arm clinical trials administered inhibitors of protein farnesylation aimed at reducing toxic...

journal_title：Circulation

authors： Gordon LB,Massaro J,D'Agostino RB Sr,Campbell SE,Brazier J,Brown WT,Kleinman ME,Kieran MW,Progeria Clinical Trials Collaborative.

更新日期：2014-07-01 00:00:00

abstract：:A longitudinal study was made of 62 patients with dextro-transposition of the great arteries. The patients were managed with balloon atrial septostomy (BAS), palliative surgery if any operation was needed in the first year of life, and Mustard intra-atrial baffle repair after one year of age. Of the 47 patients with i...

journal_title：Circulation

authors： Gutgesell HP,McNamara DG

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:There are no reported studies on the safety and efficacy of low-dose aspirin with low-intensity oral anticoagulation in patients with heart valve replacement. In this study, we compared the use of 100 mg/d aspirin with 650 mg/d aspirin in the prevention of systemic embolism and vascular death in patients wit...

journal_title：Circulation

authors： Altman R,Rouvier J,Gurfinkel E,Scazziota A,Turpie AG

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Apoptosis in human atherosclerotic coronary plaques possibly causes plaque destabilization by contributing to the weakening and breaking down of the fibrous cap. We tested the hypothesis that apoptosis is quantitatively increased in unstable atherosclerotic plaques. METHODS AND RESULTS:We analyzed the expre...

journal_title：Circulation

authors： Rossi ML,Marziliano N,Merlini PA,Bramucci E,Canosi U,Belli G,Parenti DZ,Mannucci PM,Ardissino D

更新日期：2004-09-28 00:00:00

abstract：BACKGROUND:For patients with acute dilated cardiomyopathy, definition of prognosis and of clinical features predictive of outcome is particularly important due to the availability of cardiac transplantation and other innovative treatment strategies. METHODS AND RESULTS:We reviewed our experience with 24 children under...

journal_title：Circulation

authors： Matitiau A,Perez-Atayde A,Sanders SP,Sluysmans T,Parness IA,Spevak PJ,Colan SD

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:We hypothesized that 1) endogenous adenosine released during ischemia conferred an inherent cardioprotection, and 2) a pretreatment dose of adenosine before ischemia would provide additional protection independent of hemodynamic effects. METHODS AND RESULTS:Thirty-six anesthetized New Zealand White rabbits ...

journal_title：Circulation

authors： Toombs CF,McGee S,Johnston WE,Vinten-Johansen J

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Cardiac tamponade is associated with fatal outcomes for patients with acute type A aortic dissection, and the presence of cardiac tamponade should prompt urgent aortic repair. However, treatment of the patient with critical cardiac tamponade who cannot survive until surgery remains unclear. We analyzed our e...

journal_title：Circulation

authors： Hayashi T,Tsukube T,Yamashita T,Haraguchi T,Matsukawa R,Kozawa S,Ogawa K,Okita Y

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Atrial fibrillation is common in advanced heart failure, but its prognostic significance is controversial. METHODS AND RESULTS:We evaluated the relation of atrial rhythm to overall survival and sudden death in 390 consecutive advanced heart failure patients. Etiology of heart failure was coronary artery dis...

journal_title：Circulation

authors： Middlekauff HR,Stevenson WG,Stevenson LW

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Cerebral protection during surgery for acute aortic dissection type A relies on hypothermic circulatory arrest, either alone or in conjunction with cerebral perfusion. METHODS AND RESULTS:The perioperative and intraoperative conditions of 1558 patients submitted from 44 cardiac surgery centers in German-spe...

journal_title：Circulation

authors： Krüger T,Weigang E,Hoffmann I,Blettner M,Aebert H,GERAADA Investigators.

更新日期：2011-07-26 00:00:00

abstract：:Predictability of prognosis was analyzed in 630 patients who were alive 30 days after valve replacement (1965-1986) for aortic stenosis. Follow-up totaled 4,072 patient-years. During the operative periods of 1965-1971 (n = 62), 1972-1976 (n = 164), 1977-1981 (n = 158), and 1982-1986 (n = 246), decreases in cardiothora...

journal_title：Circulation

authors： Lund O

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:We sought to define the factors associated with the occurrence of stroke and systemic embolism in a large, international atrial fibrillation (AF) trial. METHODS AND RESULTS:In ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and...

journal_title：Circulation

authors： Piccini JP,Stevens SR,Chang Y,Singer DE,Lokhnygina Y,Go AS,Patel MR,Mahaffey KW,Halperin JL,Breithardt G,Hankey GJ,Hacke W,Becker RC,Nessel CC,Fox KA,Califf RM,ROCKET AF Steering Committee and Investigators.

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:This study evaluated the hypothesis that transendocardial injections of autologous mononuclear bone marrow cells in patients with end-stage ischemic heart disease could safely promote neovascularization and improve perfusion and myocardial contractility. METHODS AND RESULTS:Twenty-one patients were enrolled...

journal_title：Circulation

authors： Perin EC,Dohmann HF,Borojevic R,Silva SA,Sousa AL,Mesquita CT,Rossi MI,Carvalho AC,Dutra HS,Dohmann HJ,Silva GV,Belém L,Vivacqua R,Rangel FO,Esporcatte R,Geng YJ,Vaughn WK,Assad JA,Mesquita ET,Willerson JT

更新日期：2003-05-13 00:00:00

abstract：BACKGROUND:Proliferation of smooth muscle cells (SMCs) plays an important role in vascular pathobiology, being involved in the development of coronary restenosis and atherosclerosis. The activation of nuclear proto-oncogenes appears to be a final common pathway onto which various mitogenic signals coverage. Accordingly...

journal_title：Circulation

authors： Shi Y,Hutchinson HG,Hall DJ,Zalewski A

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Intravascular irradiation with beta-emitters has been proposed for inhibition of restenosis in coronary arteries after balloon angioplasty or stent implantation. Previous studies have shown the effectiveness of gamma-radiation to prevent recurrent restenosis, even in the presence of an implanted stent. The l...

journal_title：Circulation

authors： Amols HI,Trichter F,Weinberger J

更新日期：1998-11-10 00:00:00

abstract：:Preliminary clinical and laboratory observations suggest that nifedipine might prevent progression of threatened myocardial infarction by reversing coronary spasm or might limit necrosis during the course of acute myocardial infarction. We screened 3143 patients with ischemic pain of greater than 45 min duration and r...

journal_title：Circulation

authors： Muller JE,Morrison J,Stone PH,Rude RE,Rosner B,Roberts R,Pearle DL,Turi ZG,Schneider JF,Serfas DH

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Long QT syndrome (LQTS) is the first described and most common inherited arrhythmia. Over the last 25 years, multiple genes have been reported to cause this condition and are routinely tested in patients. Because of dramatic changes in our understanding of human genetic variation, reappraisal of reported gen...

journal_title：Circulation

authors： Adler A,Novelli V,Amin AS,Abiusi E,Care M,Nannenberg EA,Feilotter H,Amenta S,Mazza D,Bikker H,Sturm AC,Garcia J,Ackerman MJ,Hershberger RE,Perez MV,Zareba W,Ware JS,Wilde AAM,Gollob MH

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:The aim of this study was to prospectively test whether the risk of bleeding complications in 212 consecutive outpatients treated with oral anticoagulants could be predicted by levels of endothelium-derived hemostatic variables. METHODS AND RESULTS:All bleeding complications were recorded during 5 years of ...

journal_title：Circulation

authors： Jansson JH,Boman K,Brännström M,Nilsson TK

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:In patients with atrial fibrillation (AF), the risk of thromboembolic events (TEs) is variable and is influenced by the presence and number of comorbid conditions. The effect of percutaneous left atrial radiofrequency ablation (LARFA) of AF on the risk of TEs is unclear. METHODS AND RESULTS:LARFA was perfor...

journal_title：Circulation

authors： Oral H,Chugh A,Ozaydin M,Good E,Fortino J,Sankaran S,Reich S,Igic P,Elmouchi D,Tschopp D,Wimmer A,Dey S,Crawford T,Pelosi F Jr,Jongnarangsin K,Bogun F,Morady F

更新日期：2006-08-22 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) or idiopathic hypertrophic subaortic stenosis (IHSS) has been defined as an autosomal dominant myocardial disease characterized by specific physical findings, echocardiographic features, asymmetric septal hypertrophy and disordered myocardial architecture. Echocardiographic and scinti...

journal_title：Circulation

authors： Come PC,Bulkley BH,Goodman ZD,Hutchins GM,Pitt B,Fortuin NJ

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:No information is available on the long-term results of radial artery (RA) grafts used as coronary artery bypass conduits. METHODS AND RESULTS:In this report, we describe the long-term (105+/-9 months) angiographic results of a series of 90 consecutive patients in whom the RA was used as a coronary artery b...

journal_title：Circulation

authors： Possati G,Gaudino M,Prati F,Alessandrini F,Trani C,Glieca F,Mazzari MA,Luciani N,Schiavoni G

更新日期：2003-09-16 00:00:00

abstract：:We compared the effects of a cardioselective beta-adrenergic blocking drug, metoprolol, with a nonselective beta-adrenergic blocker, propranolol, on the response of 10 normal men to dynamic treadmill exercise. The volunteers underwent a standard graded exercise test to exhaustion while receiving placebo; propranolol, ...

journal_title：Circulation

authors： Sklar J,Johnston GD,Overlie P,Gerber JG,Brammell HL,Gal J,Nies AS

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:The mechanisms responsible for the association between advanced age and atherosclerotic diseases are not clear. Because atherosclerosis develops in response to local endothelial injuries, we investigated the effect of aging on vascular healing and reendothelialization. METHODS AND RESULTS:Endothelium denuda...

journal_title：Circulation

authors： Gennaro G,Ménard C,Michaud SE,Rivard A

更新日期：2003-01-21 00:00:00

abstract：BACKGROUND:There is no published randomized study comparing amiodarone therapy and radiofrequency catheter ablation (RFA) after only 1 episode of symptomatic atrial flutter (AFL). The aim of the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) Trial of Atrial Flutter was 2-fold: (1) to prospectively compare first-line RFA...

journal_title：Circulation

authors： Da Costa A,Thévenin J,Roche F,Romeyer-Bouchard C,Abdellaoui L,Messier M,Denis L,Faure E,Gonthier R,Kruszynski G,Pages JM,Bonijoly S,Lamaison D,Defaye P,Barthélemy JC,Gouttard T,Isaaz K,Loire-Ardèche-Drôme-Isère-Puy-de-D

更新日期：2006-10-17 00:00:00

abstract：:Audible atrial sounds were noted in a patient with congestive cardiomyopathy and atrial fibrillation with slow ventricular rate. Oscillatory motion of similar periodicity as fibrillation waves in the ECG and the sounds in the phonocardiogram was demonstrated in aortic and left ventricular walls, mitral, tricuspid and ...

journal_title：Circulation

authors： Bamrah VS,Hughes CV,Tristani FE

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Perivascular adipose tissue (PVAT) surrounds most vessels and shares common features with brown adipose tissue (BAT). Although adaptive thermogenesis in BAT increases energy expenditure and is beneficial for metabolic diseases, little is known about the role of PVAT in vascular diseases such as atheroscleros...

journal_title：Circulation

authors： Chang L,Villacorta L,Li R,Hamblin M,Xu W,Dou C,Zhang J,Wu J,Zeng R,Chen YE

更新日期：2012-08-28 00:00:00