Acetaldehyde inhibits the formation of retinoic acid from retinal in the rat esophagus.

abstract：OBJECTIVE:Sofosbuvir and simeprevir in combination with standard therapy are now available for the treatment of patients chronically infected with hepatitis C virus (HCV) genotype 1. With boceprevir and telaprevir, four treatment options are, therefore, now available to clinicians. Phase 3 studies conducted with simepr...

journal_title：Scandinavian journal of gastroenterology

authors： Brochot E,Helle F,François C,Castelain S,Capron D,Nguyen-Khac E,Duverlie G

更新日期：2015-04-01 00:00:00

abstract：:Background: Neuroendocrine tumours (NETs) in the ileum grow slowly but metastasise to the liver at an early stage. After resection of the primary tumour and mesenteric lymph nodes, selected patients with liver metastases have been operated with curative intention. Recurrence-free survival seems low, suggesting that mi...

journal_title：Scandinavian journal of gastroenterology

authors： Fossmark R,Balto TM,Martinsen TC,Grønbech JE,Munkvold B,Mjønes PG,Waldum HL

更新日期：2019-08-01 00:00:00

abstract：:In a Swedish-Norwegian multicentre study patients with endoscopically verified duodenal ulcers (greater than 5 mm) were randomized to 2 or 4 weeks of treatment with either 20 mg omeprazole once daily or 300 mg ranitidine once daily. The aim was to evaluate 2 and 4 weeks' treatment with regard to symptomatic improvemen...

journal_title：Scandinavian journal of gastroenterology

authors： Glise H,Martinson J,Solhaug JH,Carling L,Unge P,Engström G,Hallerbäck B

更新日期：1991-02-01 00:00:00

abstract：:In a study comprising 100 patients referred to a surgical clinic with symptoms suggestive of gastro-oesophageal reflux disease the value of different diagnostic procedures was investigated. Positive acid perfusion and 24-h pH tests were the commonest findings. Forty-nine per cent showed a normal oesophageal mucosa or ...

journal_title：Scandinavian journal of gastroenterology

authors： Johansson KE,Ask P,Boeryd B,Fransson SG,Tibbling L

更新日期：1986-09-01 00:00:00

abstract：:Alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), alkaline phosphatase (ALP) and gamma-glutamyltranspeptidase (GT) were determined in three groups of patients: 21 with primary liver carcinoma (PLC), 106 with metastatic liver disease, and 110 with various degrees of alcoholic liver diseases. AFP was elevated in ...

journal_title：Scandinavian journal of gastroenterology

authors： Bell H

更新日期：1982-10-01 00:00:00

abstract：OBJECTIVE:Diarrhoeal relapses in patients with ulcerative colitis (UC) may be associated with enteric infections and its diagnosis may lessen avoidable exposure to corticosteroids and/or immunosuppressants. The purpose of this study was to assess the frequency of stool pathogens (parasitic and viral) in patients with a...

journal_title：Scandinavian journal of gastroenterology

authors： Banerjee D,Deb R,Dar L,Mirdha BR,Pati SK,Thareja S,Falodia S,Ahuja V

更新日期：2009-01-01 00:00:00

abstract：:BACKGROUND. Adalimumab (ADA), an antitumor necrosis factor (anti-TNF) monoclonal antibody, is effective in treating moderate-to-severely active Crohn's disease (CD). ADA has been associated with a variety of adverse events (AE). The purpose of this study is to determine the safety and efficacy of ADA in CD patients in...

journal_title：Scandinavian journal of gastroenterology

authors： Teriaky A,Gregor J,Yan B,Ponich T,Chande N,Mosli M

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Bilirubin is the main component of most common bile duct stones. Normally, almost all bilirubin in bile is conjugated to glucuronic acid or some other sugar moiety. These conjugates are unstable and liable to deconjugation. Unconjugated bilirubin is insoluble and may precipitate as the calcium salt found in ...

journal_title：Scandinavian journal of gastroenterology

authors： Sandstad O,Osnes T,Urdal P,Skar V,Osnes M

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Patients who become anergic after surgery have a very high death rate, mainly due to infectious complications. It has earlier been shown that preoperative skin testing has predictive value for the clinical outcome in gastrointestinal surgery. This study investigated the effect of early postoperative enteral ...

journal_title：Scandinavian journal of gastroenterology

authors： Beier-Holgersen R,Brandstrup B

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The scope of self-medication is increasing in many countries, and drugs for dyspepsia are a popular group for deregulative activities. This study investigated what kind of upper gastrointestinal symptoms people self-medicate and how appropriate this self-medication is. METHODS:An anonymous questionnaire was...

journal_title：Scandinavian journal of gastroenterology

authors： Sihvo S,Hemminki E

更新日期：1997-09-01 00:00:00

abstract：:The long-acting somatostatin analogue SMS 201-995, also called Sandostatin, is used in the treatment of acromegaly and peptide-secreting tumors. Little is known about its effect on gut motility, although such an effect might be expected considering the spectrum of activities of its parent molecule, somatostatin. We ha...

journal_title：Scandinavian journal of gastroenterology

authors： Peeters TL,Romanski KW,Janssens J,Vantrappen G

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:We investigated whether individuals with positive coeliac disease antibodies but without small-bowel villous atrophy have mucosal inflammation implicating gluten-sensitivity. METHODS:Small-bowel mucosal morphology; CD3+, alphabeta+, and gammadelta+ T-cell receptor-bearing intraepithelial lymphocytes; and mu...

journal_title：Scandinavian journal of gastroenterology

authors： Kaukinen K,Collin P,Holm K,Karvonen AL,Pikkarainen P,Mäki M

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Prompt and long-standing acid control following once-daily administration of antisecretory drugs is desirable. The objective of this study was to determine whether co-administration of a well-characterized H2-receptor antagonist, famotidine, can be combined with the proton-pump inhibitor omeprazole. MATERIAL...

journal_title：Scandinavian journal of gastroenterology

authors： Fändriks L,Lönroth H,Pettersson A,Vakil N

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of ADH and ALDH gene polymorphism on the development of alcoholism, alcohol liver cirrhosis and alcohol chronic pancreatitis among Polish individuals. MATERIAL AND METHODS:We determined the allele and genotype of ADH2, ADH3 and ALDH2 in 198 subjects: 57 with alcohol cirrhosis, 44 w...

journal_title：Scandinavian journal of gastroenterology

authors： Cichoz-Lach H,Partycka J,Nesina I,Celinski K,Slomka M,Wojcierowski J

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:To compare cumulative ionizing radiation in patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) for the years 2001-2011. To study how radiation exposure change over time in patients with newly diagnosed IBD and factors associated with radiation exposure. MATERIAL AND METHODS:Al...

journal_title：Scandinavian journal of gastroenterology

authors： Englund H,Lidén K K,Lind T,Sundström T,Karling P

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Ammonia, one of the pathogenic factors in Helicobacter pylori-induced mucosal injury, induces acute mucosal lesions in the rat glandular stomach. METHODS:The effect of ammonia administered intragastrically on gastric peptides was investigated in urethane-anesthetized rats. RESULTS:Gastric mucosal lesions w...

journal_title：Scandinavian journal of gastroenterology

authors： Mori S,Kaneko H,Mitsuma T,Hayakawa T,Yamaguchi C,Uruma M

更新日期：1998-04-01 00:00:00

abstract：:Ten healthy young male subjects took part in a double-blind, placebo-controlled, crossover trial to assess the effect of colloidal bismuth subcitrate (De-No) on prostaglandin (PG) E2 generation and mucosal integrity in an aspirin (ASA)-treated stomach. After administration of ASA (2.5 g) plus placebo, a marked reducti...

journal_title：Scandinavian journal of gastroenterology

authors： Konturek SJ,Kwiecień N,Obtułowicz W,Hebzda Z,Oleksy J

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:In neurophysiological studies, P300, is well known for reflecting early cognitive impairment in minimal hepatic encephalopathy (MHE). Although P300 is investigated extensively, other early event-related potential (ERP) parameters have not been studied in MHE. METHODS:The subjects were 21 adult cirrhotic pat...

journal_title：Scandinavian journal of gastroenterology

authors： Moon JH,Jun DW,Yum MK,Lee KN,Lee HL,Lee OY,Yoon BC,Choi HS,Hahm JS,Seol IJ,Oh JW,Kim CR

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:We have examined the suitability of microdialysis probes for examining nitrosative chemistry within localized regions of the lumen of the gastrointestinal tract. Chemical nitrosation occurs maximally at pH 2.5 in the presence of nitrite and thiocyanate and absence of ascorbic acid. Nitrite and thiocyanate ar...

journal_title：Scandinavian journal of gastroenterology

authors： Suzuki H,Moriya A,Iijima K,McElroy K,Fyfe VE,McColl KE

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:There has been an impression from published work that Crohn's disease is less common in southern than in northern Europe. A low incidence of Crohn's disease has been observed in Greece, but conclusive data are still lacking. METHOD:A 5-year prospective and population-based epidemiologic study of Crohn's dis...

journal_title：Scandinavian journal of gastroenterology

authors： Manousos ON,Koutroubakis I,Potamianos S,Roussomoustakaki M,Gourtsoyiannis N,Vlachonikolis IG

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Lacunae exist on the identity of specific environmental risk factors that associate with Crohn's disease (CD). We hypothesized that indirect exposures acquired via the parents' occupation may confer susceptibility. METHODS:A case-control study based on children diagnosed with CD (prior to age...

journal_title：Scandinavian journal of gastroenterology

authors： Eslahpazir J,Kumar R,Lalavi A,Amre DK

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Morbidity and mortality following perforated peptic ulcer (PPU) remain substantial. In the recently published PULP trial, 30-day mortality in patients surgically treated for PPU decreased from 27% to 17% following the implementation of a perioperative care protocol based on The Surviving Sepsis Guidelines. Th...

journal_title：Scandinavian journal of gastroenterology

authors： Møller MH,Vester-Andersen M,Thomsen RW

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Serum leptin levels are elevated in alcoholic liver cirrhosis and thus might be involved in the anorexia and hypermetabolism often seen in those patients. We hypothesized that the leptin system is modulated in patients with hepatitis C and might be affected by antiviral therapy. The aim of this study was to ...

journal_title：Scandinavian journal of gastroenterology

authors： Widjaja A,Wedemeyer H,Tillmann HL,Horn R,Ockenga J,Jaeckel E,von zur Mühlen A,Manns MP,Brabant G

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Atrophic gastritis (AG) is a risk condition for gastric cancer and type I gastric carcinoids. Recent studies assessing the overall risk of gastric cancer and carcinoids in AG at long-term follow up are lacking. This study aimed to investigate in a prospective cohort of AG patients the occurrence of gastric ca...

journal_title：Scandinavian journal of gastroenterology

authors： Lahner E,Esposito G,Pilozzi E,Purchiaroni F,Corleto VD,Di Giulio E,Annibale B

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Infection rates are high in patients with ulcer disease, but even non-ulcer dyspepsia (NUD) patients have Helicobacter pylori infection. The Notodden Helicobacter study is an 'outcome study' of clinical practice in a local hospital. The study may identify factors associated with infection and evaluate whethe...

journal_title：Scandinavian journal of gastroenterology

authors： Thürmer HL,Flaaten B,Erichsen KE,Lid NO,Solheim SB

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:To compare the effect of combination therapy with interferon-alpha (INF-alpha) and granulocyte-macrophage colony-stimulating factor (GM-CSF) to monotherapy with INF-alpha in patients with chronic hepatitis C infection. METHODS:Forty-five consecutive patients with chronic hepatitis C, all presenting with ele...

journal_title：Scandinavian journal of gastroenterology

authors： Grønbaek K,Krarup HB,Ring-Larsen H,Schaffalitzky de Muckadell O,Møller A,Schlichting P,Vyberg M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Beneficial effects of lactobacilli have been reported in experimental colitis. On the other hand, despite the controversial role of nitric oxide (NO) in the inflammatory gut process, a protective action of exogenous NO in inflammation has been suggested. Consequently, this study aimed to determine the effect...

journal_title：Scandinavian journal of gastroenterology

authors： Lamine F,Fioramonti J,Bueno L,Nepveu F,Cauquil E,Lobysheva I,Eutamène H,Théodorou V

更新日期：2004-01-01 00:00:00

abstract：:The effect of intravenous administration of adrenaline, noradrenaline, and isoprenaline on gastric mucosal flow, measured by hydrogen clearance techniques, showed that small doses of adrenaline induced slight mucosal vasodilatation in anaesthetized cats. In both anaesthetized and conscious animals both noradrenaline a...

journal_title：Scandinavian journal of gastroenterology

authors： Semb BK

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVE:In celiac disease (CD), enteropathy of the small bowel results from a T-cell-mediated reaction to gluten in the diet. In addition to gluten, other environmental and genetic factors participate in the disease pathogenesis. We have recently reported the finding of a significantly different short-chain fatty aci...

journal_title：Scandinavian journal of gastroenterology

authors： Tjellström B,Stenhammar L,Högberg L,Fälth-Magnusson K,Magnusson KE,Midtvedt T,Sundqvist T,Houlston R,Popat S,Norin E

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The functional role of the intracellular diacylglycerol/protein kinase C second-messenger pathway in the regulation of gastric acid secretion and the effects on the involved inositotrisphosphate/Ca2+/calmodulin system are not well understood, and contradictory data have been reported. We therefore evaluated ...

journal_title：Scandinavian journal of gastroenterology

authors： Kopp R,Pfeiffer A

更新日期：2000-07-01 00:00:00