Abstract:
:Despite a dramatic decline in mortality over the past three decades, coronary heart disease is the leading cause of death and disability in the U.S. Importantly, recent advances in the field of cardiovascular medicine have not led to significant declines in case fatality rates for women when compared to the dramatic declines realized for men. The current review highlights gender-specific issues in ischemic heart disease presentation, evaluation, and outcomes with a special focus on the results published from the National Institutes of Health-National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study. We will present recent evidence on traditional and novel risk markers (e.g., high sensitivity C-reactive protein) as well as gender-specific differences in symptoms and diagnostic approaches. An overview of currently available diagnostic test evidence (including exercise electrocardiography and stress echocardiography and single-photon emission computed tomographic imaging) in symptomatic women will be presented as well as data using innovative imaging techniques such as magnetic resonance subendocardial perfusion, and spectroscopic imaging will also be discussed.
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Shaw LJ,Bairey Merz CN,Pepine CJ,Reis SE,Bittner V,Kelsey SF,Olson M,Johnson BD,Mankad S,Sharaf BL,Rogers WJ,Wessel TR,Arant CB,Pohost GM,Lerman A,Quyyumi AA,Sopko G,WISE Investigators.doi
10.1016/j.jacc.2005.01.072subject
Has Abstractpub_date
2006-02-07 00:00:00pages
S4-S20issue
3 Suppleissn
0735-1097issn
1558-3597pii
S0735-1097(05)02506-4journal_volume
47pub_type
杂志文章,评审abstract:OBJECTIVES:To assess whether 15-(p-[iodine-123] iodophenyl)-3-(R,S) methylpentadecanoic acid (BMIPP) imaging can identify previous ischemic areas, BMIPP SPECT was performed in patients with acute chest pain to compare its findings with those of technetium-99m-tetrofosmin (tetrofosmin) SPECT and coronary angiography. B...
journal_title:Journal of the American College of Cardiology
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abstract:OBJECTIVES:The aim of this study was to evaluate measurement accuracy of cardiac output in humans by comparing the indicator-dilution technique with geometric analysis by ultrafast computed tomography. BACKGROUND:Ultrafast computed tomography can be used to measure cardiac output by two methods. First, by scanning to ...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/0735-1097(93)90328-x
更新日期:1993-05-01 00:00:00
abstract::The prognostic value of radionuclide measures of left ventricular function at rest and exercise is well established. Some studies have suggested that the frequency and duration of silent ischemia during ambulatory monitoring provide similar prognostic information; however, studies comparing these two techniques have n...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(92)90279-v
更新日期:1992-04-01 00:00:00
abstract::A 68 year old man had a diaphragmatic myocardial infarction and 9 months later was admitted with severe congestive heart failure (functional class IV). Cardiac catheterization demonstrated a postinfarction pseudoaneurysm. Because of a massive left to right shunt (pulmonary to systemic flow ratio = 2.7), concomitant ru...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(85)80284-9
更新日期:1985-07-01 00:00:00
abstract:OBJECTIVES:This study investigated the incidence, predisposing factors and significance of the onset of atrial fibrillation (AF) in patients with chronic congestive heart failure (CHF). BACKGROUND:The association between CHF and AF is well documented, but the factors that predispose to the onset of the arrhythmia and ...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(98)00221-6
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVES:The purpose of the study is to identify the predictors of clinical outcome (mortality and survival without repeat septal reduction procedures) of alcohol septal ablation for the treatment of patients with hypertrophic obstructive cardiomyopathy. BACKGROUND:Alcohol septal ablation is used for treatment of me...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jacc.2011.06.073
更新日期:2011-11-22 00:00:00
abstract:OBJECTIVES:Our purpose was to quantify the frequency and distribution of suspected vulnerable lesions, defined as thin-capped fibroatheroma (TCFA) and ruptured plaque, in human coronary artery autopsy specimens. BACKGROUND:Most acute coronary events and sudden death are believed to arise from rupture of a TCFA followe...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/j.jacc.2007.04.086
更新日期:2007-09-04 00:00:00
abstract:OBJECTIVES:The goal of this study was to better characterize the young patient with aortic dissection (AoD). BACKGROUND:Aortic dissection is unusual in young patients, and frequently associated with unusual presentations. METHODS:Data were collected on 951 patients diagnosed with AoD between January 1996 and November...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/j.jacc.2003.08.054
更新日期:2004-02-18 00:00:00
abstract::Heart rate variability has been demonstrated both experimentally and clinically to be of prognostic importance in determining mortality after myocardial infarction. However, no paired studies have been reported to examine heart rate variability before and after myocardial infarction. The hypothesis was tested that low...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(10)80351-1
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVES:We investigated the acute effect of orally administered high-dose folic acid on coronary dilator function in humans. BACKGROUND:Folic acid and its active metabolite, 5-methyltetrahydrofolate, increase endothelium-dependent vasodilation in human peripheral circulation. However, the acute effect on coronary c...
journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2005-05-17 00:00:00
abstract:OBJECTIVES:In patients with atrial flutter (AFL) and postoperative right atrial incisional scars, we sought to assess if the use of additional ablative lesions that targeted all potential re-entrant circuits, regardless of the presenting type of flutter, would prevent long-term recurrence. BACKGROUND:Patients with AFL...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2004.04.045
更新日期:2004-07-21 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.jacc.2016.05.084
更新日期:2016-08-30 00:00:00
abstract:OBJECTIVES:The purpose of this study was to assess the value of cardiovascular magnetic resonance (CMR)-determined graft flow and flow reserve in differentiating significant from non-significant vein graft disease. BACKGROUND:In patients after coronary artery bypass grafting (CABG), non-invasive testing may be helpful...
journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0735-1097(02)02491-9
更新日期:2002-11-20 00:00:00
abstract::Although the use of oral anticoagulants (vitamin K antagonists) has been abandoned in primary cardiovascular prevention due to lack of a favorable benefit-to-risk ratio, the indications for aspirin use in this setting continue to be a source of major debate, with major international guidelines providing conflicting re...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jacc.2014.03.049
更新日期:2014-07-22 00:00:00
abstract:OBJECTIVES:The goal of this study was to identify genes upregulated in the heart in human patients with hypertrophic cardiomyopathy (HCM). BACKGROUND:Hypertrophic cardiomyopathy is a genetic disease caused by mutations in contractile sarcomeric proteins. The molecular basis of diverse clinical and pathologic phenotype...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(01)01509-1
更新日期:2001-10-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
doi:10.1016/s0735-1097(02)01749-7
更新日期:2002-04-03 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:2020-06-23 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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更新日期:2016-05-10 00:00:00
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journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(86)80460-0
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更新日期:1994-04-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(99)00028-5
更新日期:1999-03-01 00:00:00
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doi:10.1016/s0735-1097(00)01193-1
更新日期:2001-03-01 00:00:00
abstract::SCOT-HEART (Scottish COmputed Tomography of the HEART) and PROMISE (PROspective Multicenter Imaging Study for Evaluation of chest pain) represent the 2 largest and most comprehensive cardiovascular imaging outcome trials in patients with stable chest pain and provide significant insights into patient diagnosis, manage...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jacc.2015.11.055
更新日期:2016-02-23 00:00:00
abstract:OBJECTIVES:We tested the hypothesis that one health status measure, the Kansas City Cardiomyopathy Questionnaire (KCCQ), provides prognostic information independent of other clinical data in outpatients with heart failure (HF). BACKGROUND:Health status measures are used to describe a patient's clinical condition and h...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jacc.2005.11.021
更新日期:2006-02-21 00:00:00
abstract::Compared with recent advances in treatment of serious cardiovascular diseases, such as myocardial infarction and stroke, the treatment and outcome of acute pulmonary embolism (PE) have remained relatively unchanged over the last few decades. This has prompted several experts to call for the formation of multidisciplin...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jacc.2015.12.024
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:This retrospective study was designed to determine the six-month angiographic outcome after stenting of native coronary arteries in insulin-treated (ITDM) and non-ITDM patients with diabetes mellitus (DM) and compare the results with those in non-DM patients. BACKGROUND:The influence of the treatment modali...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(00)00574-x
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to explore post-myocardial infarction (MI) myocardial inflammation. BACKGROUND:Innate immune cells are centrally involved in infarct healing and are emerging therapeutic targets in cardiovascular disease; however, clinical tools to assess their presence in tissue are scarce. Furthe...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2011.08.066
更新日期:2012-01-10 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0735-1097(99)00542-2
更新日期:2000-02-01 00:00:00
abstract::Patients with portal hypertension of varying etiology may develop pulmonary artery hypertension. In the present autopsy study, pulmonary and hepatic tissue was studied in 12 patients in whom pulmonary and portal hypertension coexisted. Plexogenic pulmonary arteriopathy was present in 10 patients, 7 of whom had coexist...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(87)80123-7
更新日期:1987-12-01 00:00:00