Abstract:
OBJECTIVES:The aim of this study was to evaluate measurement accuracy of cardiac output in humans by comparing the indicator-dilution technique with geometric analysis by ultrafast computed tomography. BACKGROUND:Ultrafast computed tomography can be used to measure cardiac output by two methods. First, by scanning to obtain end-systolic and end-diastolic short-axis images of the ventricular cavities at sequential tomographic levels, the stroke volume and therefore the cardiac output can be calculated. Second, indicator-dilution theory (the Stewart-Hamilton equation) can be applied to measurements of the concentration of radiographic contrast in the blood pool after a bolus injection. The latter method has not been validated in humans. METHODS:The accuracy of the geometric method itself was first established by comparing left and right ventricular stroke volumes in 29 patients without valvular regurgitation or an intracardiac shunt, whose left and right ventricular stroke volumes should have been identical (group A). In a subset of 17 patients, the geometric method was compared with the indicator-dilution method (group B). RESULTS:Geometric analysis showed that the mean difference between left and right ventricular stroke volume was 1.8 +/- 7.3 ml, with a percentage SD of the differences of 9.3% (r = 0.9). Comparison wih indicator dilution-calculated cardiac output showed a mean difference of 0.079 +/- 1.22 liters/min, with a percent SD of the differences of 23.7% (r = 0.6). There was no improvement in this comparison with individual calibration of the scanner for each patient. CONCLUSIONS:The disparity found between data obtained with the geometric and indicator-dilution methods may be a result of the hemodynamic effects of contrast medium or it may suggest the possibility that some assumptions of indicator-dilution theory are not valid.
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Ludman PF,Coats AJ,Poole-Wilson PA,Rees RSdoi
10.1016/0735-1097(93)90328-xsubject
Has Abstractpub_date
1993-05-01 00:00:00pages
1482-9issue
6eissn
0735-1097issn
1558-3597pii
0735-1097(93)90328-Xjournal_volume
21pub_type
杂志文章abstract:BACKGROUND:Enterococcal endocarditis (EE) is a growing entity in Western countries. However, quality data from large studies is lacking. OBJECTIVES:The purpose of this study was to describe the characteristics and analyze the prognostic factors of EE in the GAMES cohort. METHODS:This was a post hoc analysis of a pros...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jacc.2019.11.047
更新日期:2020-02-11 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine whether patients with ventricular arrhythmias in the absence of coronary artery disease also have abnormalities in sympathetic innervation. BACKGROUND:We have previously shown by cardiac sympathetic scintigraphy using iodine-123-metaiodobenzylguanidine (I-123-MIBG) tha...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/0735-1097(93)90541-8
更新日期:1993-11-01 00:00:00
abstract::Thirty patients with stable exertional angina undergoing percutaneous transluminal coronary angioplasty of an isolated obstructive lesion of the proximal left anterior descending artery were prospectively evaluated to investigate the relation between angina induced by balloon inflation and the quantity and severity of...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(87)80189-4
更新日期:1987-09-01 00:00:00
abstract::Although transient increases in heart rate typically occur, bradycardia has infrequently been noted in association with partial seizures. Five patients with temporal lobe epilepsy are described in whom sinus bradyarrhythmias and syncope were prominent manifestations of seizure activity. Partial improvement occurred in...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(90)90290-6
更新日期:1990-03-15 00:00:00
abstract::The efficacy of truncated exponential waveform shocks using a cardioverter-defibrillator catheter with and without a 13.9 cm2 subcutaneous thoracic patch electrode was examined in 10 pentobarbital-anesthetized dogs. The cardioverter-defibrillator catheter was positioned through the external jugular vein with the dista...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(87)80025-6
更新日期:1987-08-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(95)80012-6
更新日期:1995-08-01 00:00:00
abstract::Arginine vasopressin, a potent vasoconstrictor and regulator of body water, is frequently increased in the plasma of patients with congestive heart failure. Other neurohumoral control networks, such as the sympathetic nervous system and the renin-angiotensin system, also demonstrate increased activity in congestive he...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(83)80333-7
更新日期:1983-12-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2006.09.054
更新日期:2007-03-13 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2008-07-08 00:00:00
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更新日期:1998-07-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
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更新日期:1992-08-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-08-01 00:00:00
abstract:OBJECTIVES:We attempted to determine whether continuous wave Doppler backscatter power could be used to quantify mitral regurgitation. BACKGROUND:The power of a Doppler backscatter signal is proportional to the number of scatterers insonated and, hence, to the moving volume of blood. The relative power of the continuo...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(94)90016-7
更新日期:1994-09-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2017-06-27 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
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更新日期:1994-02-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(95)00262-2
更新日期:1995-10-01 00:00:00
abstract::The American College of Cardiology Adult Congenital and Pediatric Cardiology (ACPC) Section had attempted to create quality metrics (QM) for ambulatory pediatric practice, but limited evidence made the process difficult. The ACPC sought to develop QMs for ambulatory pediatric cardiology practice. Five areas of interes...
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pub_type: 杂志文章,评审
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更新日期:2017-02-07 00:00:00
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更新日期:2009-09-15 00:00:00
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更新日期:2009-08-04 00:00:00
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更新日期:2011-08-09 00:00:00
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doi:10.1016/s0735-1097(87)80301-7
更新日期:1987-05-01 00:00:00
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doi:10.1016/j.jacc.2012.03.071
更新日期:2012-08-28 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:1997-07-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
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更新日期:1999-09-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:1992-07-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:1995-03-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章
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更新日期:1985-09-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(00)00549-0
更新日期:2000-04-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:2001-11-01 00:00:00
abstract::The current study determined the effectiveness of nicardipine, a 1,4-dihydropyridine calcium antagonist, in preserving reperfused myocardium in a cat model of temporary coronary occlusion and ascertained if replenishment of myocardial phosphate stores during reperfusion as defined by phosphorus-31 nuclear magnetic res...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(90)90328-m
更新日期:1990-12-01 00:00:00