Reye's syndrome; diagnosis by muscle biopsy?

Abstract:

:Three children with Reye's syndrome are described. One child died, the second had mild and transient illness, and the third had recurrent episodes. In all 3 children a muscle biopsy showed pronounced infiltration of the myofibres with fat microdroplets as shown by the oil red O stain and by electron microscopical examination. We suggest that needle biopsy of muscle may be a quick and safe aid to the diagnosis of Reye's syndrome, and may be preferable to liver biopsy in view of the pronounced tendency to bleed in Reye's syndrome.

journal_name

Arch Dis Child

authors

Shapira Y,Deckelbaum R,Statter M,Tennenbaum A,Aker M,Yarom R

doi

10.1136/adc.56.4.287

subject

Has Abstract

pub_date

1981-04-01 00:00:00

pages

287-91

issue

4

eissn

0003-9888

issn

1468-2044

journal_volume

56

pub_type

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