Abstract:
:Twenty five patients with encephalitis were studied prospectively, and their clinical and virological features compared with outcome. Among 22 patients with laboratory confirmation of virus infection, evidence of direct effect on the central nervous system by the virus occurred significantly more often both in those with a monophasic illness compared with those with a biphasic illness, and in those with focal neurological signs localising in the cerebral hemispheres compared with those without such signs. Young age at presentation, low score on the Glasgow coma scale, disruption of oculocephalic responses, and laboratory evidence of virus infection within the central nervous system were significantly associated with poor outcome. Computed tomography results, concentrations of creatine phosphokinase BB isoenzyme in cerebrospinal fluid, and procoagulant activity in cerebrospinal fluid were not predictive of outcome.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Kennedy CR,Duffy SW,Smith R,Robinson ROdoi
10.1136/adc.62.11.1156subject
Has Abstractpub_date
1987-11-01 00:00:00pages
1156-62issue
11eissn
0003-9888issn
1468-2044journal_volume
62pub_type
杂志文章abstract::In a study of 256 families, among whom were twins, midparent-adult son correlations for height, weight, and combined skinfold measurements were 0.67, 0.47, and 0.23 respectively. The corresponding midparent-adult daughter correlations were 0.63, 0.42, and 0.24. Midparent-growing offspring correlations were highest for...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.11.877
更新日期:1979-11-01 00:00:00
abstract::Two patients with raised intracranial pressure responding to ventriculoperitoneal shunting are described in whom ultrasound failed to show dilated ventricles. The importance of not equating absence of ventricular dilatation with normal pressure and ventricular dilatation with high pressure is emphasised. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.6.581
更新日期:1985-06-01 00:00:00
abstract::Persistent daytime incontinence is a fairly uncommon but important problem. Videourodynamic studies were carried out in 215 children presenting with this problem in whom there were no neurological signs and who had not responded to simple measures. Over 90% of symptomatic children were shown to have an abnormality, of...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.2.128
更新日期:1987-02-01 00:00:00
abstract::General practice records of 1058 children were studied to determine the incidence, prevalence, natural history, diagnosis, and treatment of wheezing presenting in the first 21 years of life. Up to 7 years of age, boys were more likely to present with wheeze and to have recurrent episodes. Later there was a higher inci...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.5.457
更新日期:1985-05-01 00:00:00
abstract::Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug substance, the necessary dose and the age-appropriateness of the formulation. Generally, the younger the child, the more the attention that is required. For decades, there has been a general lack of (authorised) formulations ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2015-308227
更新日期:2016-07-01 00:00:00
abstract::The association between current micturition habits and previous urinary tract infection was analysed among 3553 school entrants aged 7 years by means of a questionnaire. A high incidence of urinary infection, confirmed by urine culture, was found (145 (8.4%) in the 1719 girls and 32 (1.7%) in the 1834 boys). There was...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.2.232
更新日期:1991-02-01 00:00:00
abstract::Trigeminal neuralgia (TN) is a frequent cause of paroxysmal facial pain and headache in adults. Glossopharyngeal neuralgia (GPN) is less common, but can cause severe episodic pain in the ear and throat. Neurovascular compression of the appropriate cranial nerve as it leaves the brain stem is responsible for the sympto...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.82.4.311
更新日期:2000-04-01 00:00:00
abstract::The term Ehlers-Danlos syndrome (EDS) encompasses a group of inherited connective tissue disorders. The manifestations of EDS can be seen in skin, joints, blood vessels and internal organs and vary from mild to severe and life threatening. Each subtype is a separate and different condition. The genetic basis of many s...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2013-304822
更新日期:2015-01-01 00:00:00
abstract::Lipofuscin develops in cells when peroxidation damage occurs. Its development in the liver of patients receiving prolonged parenteral nutrition suggests that peroxidation damage by free radicals has occurred. Deficiencies in antioxidants such as vitamin E may be an important contributing factor. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.8.774
更新日期:1985-08-01 00:00:00
abstract::Dubowitz et al. have offered a scoring system for estimating the gestational age of newborn babies. If the system is applied to twin pairs, the heavier twin is generally estimated to have a greater gestational age than the lighter one. Previously this has been interpreted as a flaw in the scoring system. However, it m...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.55.4.281
更新日期:1980-04-01 00:00:00
abstract::Bilateral staghorn renal calculi in a 7-year-old girl with cystinuria were dissolved over a period of 6 months, using a high fluid intake, urinary alkalinisation, and D-penicillamine. Even in children with extensive cystine urolithiasis, medical management may avert the need for surgery. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.10.795
更新日期:1979-10-01 00:00:00
abstract:BACKGROUND:Rectal measurement is considered a gold standard in many healthcare systems for body temperature measurement in children. Although this method has several disadvantages, an ideal alternative thermometer has not yet been introduced. However tympanic and infrared skin thermometers are potential alternatives. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2010.185801
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:A subnormal cortisol response (30 min level (C30min)<550 nmol/L) to synthetic adrenocorticotrophic hormone/Synacthen test (SDST) in all infants does not necessarily indicate underlying or persistent hypothalamic-pituitary-adrenal axis pathology. METHODS:We retrospectively evaluated the diagnoses and outcome...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2017-313819
更新日期:2018-10-01 00:00:00
abstract::All 212 neonates undergoing cardiac surgery at this hospital during the 5-year period from 1976 to 1980 inclusive were reviewed. Forty required open heart surgery with 23 (57%) deaths. One hundred and seventy-four neonates underwent non-bypass procedures and could be divided into three groups: group 1 (82 patients) ha...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.58.2.137
更新日期:1983-02-01 00:00:00
abstract::Three babies said to have had 'meconium stained liquor' were subsequently found never to have passed meconium. The green discoloured liquor was the result of bilious vomiting in utero secondary to intestinal obstruction. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.63.2.201
更新日期:1988-02-01 00:00:00
abstract::The neurodevelopmental state of 41 children with congenital cytomegalovirus infection and their controls was assessed at 2 years using the Griffiths scale. The scores achieved by children with congenital cytomegalovirus but with no associated neurological abnormality (asymptomatic) were similar to those of the control...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.4.323
更新日期:1986-04-01 00:00:00
abstract::The duration of symptoms before diagnosis (lag time) was defined for 184 of 236 children diagnosed as having a malignancy at the Royal Hospital for Sick Children, Edinburgh for the time period January 1982 until December 1990. The natural logarithm of the lag time was correlated with age, gender, diagnostic group, whi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.6.771
更新日期:1993-06-01 00:00:00
abstract::A questionnaire study regarding airway morbidity in children and environmental factors was performed in April 1985. The parents of 5301 children, aged 6 months to 16 years, from different rural areas in mid Sweden were sent a validated questionnaire and 4990 (94%) responded. The cumulative prevalence of bronchial hype...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.63.5.473
更新日期:1988-05-01 00:00:00
abstract:OBJECTIVE:To compare dual therapy (omeprazole and amoxicillin) with triple therapy (omeprazole, amoxicillin, and clarithromycin) in the treatment of Helicobacter pylori infection. The efficacy of 1 mg/kg/day omeprazole was randomly compared with 2 mg/kg/day. STUDY DESIGN:252 patients (median age, 11.0 years; range, 3-...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1136/adc.81.1.68
更新日期:1999-07-01 00:00:00
abstract::A child with chronic diarrhoea since birth responded to the prostaglandin synthetase inhibitors aspirin and indomethacin. During a period without treatment, raised levels of prostaglandins F2alpha and E2 were observed. No source for these raised prostaglandins was shown, and it is suggested that she may have an inborn...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.10.800
更新日期:1977-10-01 00:00:00
abstract::Samples of saliva and nasal secretions were collected sequentially from 15 breast fed and 15 bottle fed infants on five occasions between 6 days and 9 months of age. Total immunoglobulin concentrations of G, M, and A classes, and class specific antibodies to tetanus toxoid and a pool of commensal strains of Escherichi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.3.263
更新日期:1986-03-01 00:00:00
abstract::The communication development in 11 children with Angelman's syndrome is described. The clinical observation that these children appear to have a greater ability with receptive rather than expressive language is investigated and these skills assessed using published communication schedules. In addition the understandi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.69.1.148
更新日期:1993-07-01 00:00:00
abstract::The status of 732 children suffering from cerebral palsy from the South East Thames region (births from 1970-9) was ascertained at the end of 1989, and copies of death certificates of the 73 children who have died, aged 4 weeks to nearly 16 years, were obtained. Infantile cerebral palsy (ICD Code 343-) was coded as th...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.3.325
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:In a national study of Australian children aged 11-12 years old, we examined the (1) prevalence and characteristics of hearing loss, (2) its demographic risk factors and (3) evidence for secular increases since 1990. METHODS:This is a cross-sectional CheckPoint wave within the Longitudinal Study of Australia...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2017-313505
更新日期:2018-06-01 00:00:00
abstract::The concentrations of immunoglobulins (Ig) G.A.M. and E were determined in paired umbilical cord and maternal sera in 50 twin pregnancies. Mean IgG levels were higher in cord than maternal sera and in most cases the cord IgG level related more closely to that of the other twin than to either maternal level or birthwei...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.5.354
更新日期:1976-05-01 00:00:00
abstract::Hospital clowning is a programme in healthcare facilities involving visits from specially trained actors. In the paediatric intensive care unit (PICU), clowning may appear inappropriate and less intuitive. The patient could appear too ill and/or sedated, the environment too crowded or chaotic and the parents too stres...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2016-311583
更新日期:2017-07-01 00:00:00
abstract::A retrospective analysis was made of the incidence and severity of the idiopathic respiratory distress syndrome (RDS) in babies of less than 35 weeks' gestation born at this hospital from January 1967-December 1974. There was a lower incidence of RDS in babies born after pregnancies complicated only by prolonged ruptu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.9.674
更新日期:1976-09-01 00:00:00
abstract::In a 4-year period the neonatal survival rate for 26 infants weighing 501-750 g was 42% and for 81 infants weighing 751-1000 g it was 61%. All 59 surviving infants have been assessed at follow-up; 39 were at least 2 years old (corrected for prematurity) and data from the remaining 20 were derived from assessment at 1 ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.57.11.823
更新日期:1982-11-01 00:00:00
abstract:BACKGROUND:Morbidity and mortality remain high following infant cardiac arrest. Optimal cardiopulmonary resuscitation (CPR) is therefore imperative. OBJECTIVE:Comparison of two-thumb (TT) and two-finger (TF) infant chest compression technique compliance with international recommendations. DESIGN:Randomised cross-over...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,随机对照试验
doi:10.1136/archdischild-2012-302583
更新日期:2013-08-01 00:00:00
abstract:UNLABELLED:One hundred and seventy three children, including 93 with biliary atresia, received liver grafts at Addenbrooke's Hospital between 1983 and 1993. Of these, only seven developed cyanosis due to intrapulmonary shunting as a complication of their liver disease, and all seven of these had the biliary atresia/pol...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.70.6.501
更新日期:1994-06-01 00:00:00