Cytotoxicity and aryl hydrocarbon receptor-mediated activity of n-heterocyclic polycyclic aromatic hydrocarbons: structure-activity relationships.

abstract：:Vitellogenin (VTG) induction has proved to be a valuable biomarker for assessing exposure to environmental estrogens in fish. The widespread use of VTG in this regard has lead to the need for standardized assays to quantify VTG, and monoclonal antibodies have the potential to help accomplish this. A VTG enzyme-linked ...

journal_title：Environmental toxicology and chemistry

authors： Tyler CR,van Aerle R,Nilsen MV,Blackwell R,Maddix S,Nilsen BM,Berg K,Hutchinson TH,Goksøyr A

更新日期：2002-01-01 00:00:00

abstract：:We examined the subcellular partitioning of zinc (Zn) in Daphnia magna both under acute and chronic exposures. In the acute Zn toxicity tests, the daphnids were exposed to different Zn concentrations for 48 h or to one lethal concentration (1,000 microg/L) for different durations (time to death for up to 47 h). Signif...

journal_title：Environmental toxicology and chemistry

authors： Wang WX,Guan R

更新日期：2010-08-01 00:00:00

abstract：:Herbicides are commonly used in agriculture and silviculture to reduce interspecific competition among plants and thereby enhance crop growth, quality, and volume. Internationally, glyphosate-based herbicides are the most widely used herbicides in both of these sectors. Laboratory and mesocosm studies have demonstrate...

journal_title：Environmental toxicology and chemistry

authors： Edge CB,Thompson DG,Hao C,Houlahan JE

更新日期：2012-10-01 00:00:00

abstract：:Uptake and membrane transport of cadmium (Cd) in roots of the hyperaccumulator Sedum plumbizincicola X.H. Guo et S.B. Zhou ex L.H. Wu was characterized by assessing the impact of various inhibitors and ion channel blockers on Cd accumulation as well as the real-time net Cd2+ flux at the roots with application of the s...

journal_title：Environmental toxicology and chemistry

authors： Li LZ,Tu C,Wu LH,Peijnenburg WJ,Ebbs S,Luo YM

更新日期：2017-04-01 00:00:00

abstract：:A hybrid model based on the positive matrix factorization (PMF) model and the health risk assessment model for assessing risks associated with sources of perfluoroalkyl substances (PFASs) in water was established and applied at Dianchi Lake to test its applicability. The new method contains 2 stages: 1) the sources of...

journal_title：Environmental toxicology and chemistry

authors： Xu J,Shi GL,Guo CS,Wang HT,Tian YZ,Huangfu YQ,Zhang Y,Feng YC,Xu J

更新日期：2018-01-01 00:00:00

abstract：:The dissolved uptake rate constant (k(u)), dietary assimilation efficiency (AE), and efflux rate constant (k(e)) of cadmium (Cd) and zinc (Zn) were quantified in a freshwater zooplankton Daphnia magna cultured at different ambient calcium (Ca) concentrations. The animals were first acclimated to different ambient Ca l...

journal_title：Environmental toxicology and chemistry

authors： Tan QG,Wang WX

更新日期：2008-07-01 00:00:00

abstract：:Liver and kidneys from grey seals (Halichoerus grypus) in their natural habitats in Norwegian waters contain high levels of Cd and Hg as well as metallothionein (MT). The data show significant placental transfer of heavy metals in seals. The MT concentrations were higher in fetus liver and kidneys than in the liver an...

journal_title：Environmental toxicology and chemistry

authors： Teigen SW,Andersen RA,Daae HL,Skaare JU

更新日期：1999-10-01 00:00:00

abstract：:A suite of mechanistic atmospheric and mercury (Hg) cycling and bioaccumulation models is applied to simulate atmospheric Hg deposition and Hg concentrations in the water column and in fish in a Hg-impaired freshwater lake located in the northeastern United States that receives its Hg loading primarily through deposit...

journal_title：Environmental toxicology and chemistry

authors： Vijayaraghavan K,Levin L,Parker L,Yarwood G,Streets D

更新日期：2014-06-01 00:00:00

abstract：:The sublethal effects of lead (Pb) on the earthworm Eisenia fetida were evaluated in the laboratory using freshly spiked soil and soil collected from Canadian prairie skeet ranges. After a four-week exposure to soil spiked with lead acetate, earthworm neutral red retention time (NRRT). soil Pb concentrations, and eart...

journal_title：Environmental toxicology and chemistry

authors： Booth L,Palasz F,Darling C,Lanno R,Wickstrom M

更新日期：2003-10-01 00:00:00

abstract：:The increased application of nanoparticles (NPs) is increasing the risk of their release into the environment. Although many toxicity studies have been conducted, the environmental risk is difficult to estimate, because uptake mechanisms are often not determined in toxicity studies. In the present study, the authors r...

journal_title：Environmental toxicology and chemistry

authors： Kettler K,Veltman K,van de Meent D,van Wezel A,Hendriks AJ

更新日期：2014-03-01 00:00:00

abstract：:A method is presented for extending the target lipid model (TLM) of narcotic toxicity to polar narcotic chemicals. The proposed polyparameter TLM extends the applicability of the TLM by including polar compounds and removing explicit chemical class corrections. The validity of the model is tested using a data set of 1...

journal_title：Environmental toxicology and chemistry

authors： Kipka U,Di Toro DM

更新日期：2009-07-01 00:00:00

abstract：:In this study, we assessed and compared the suitability of three in vitro screening tools for the measurement of estrogenic activity in sewage treatment plant effluents (STPEs). These assays were the yeast estrogen screen (YES), production of zona radiata proteins (ZRPs) in trout hepatocytes, and the induction of repo...

journal_title：Environmental toxicology and chemistry

authors： Rutishauser BV,Pesonen M,Escher BI,Ackermann GE,Aerni HR,Suter MJ,Eggen RI

更新日期：2004-04-01 00:00:00

abstract：:Most toxicity tests investigate constant concentrations of a chemical. Concentrations of many compounds in the environment are dynamic, however, and individuals may be more sensitive to pulses of a chemical initiated at specific points during development. Realistic toxicity tests are important to accurately assess the...

journal_title：Environmental toxicology and chemistry

authors： Earl JE,Whiteman HH

更新日期：2009-06-01 00:00:00

abstract：:Contaminants have been associated with population declines of several amphibian species in California (USA). Pesticides from the Central Valley of California are transported by winds into the Sierra Nevada Mountains and precipitate into wet meadows where amphibians breed. The present study examined the chronic toxicit...

journal_title：Environmental toxicology and chemistry

authors： Sparling DW,Fellers GM

更新日期：2009-08-01 00:00:00

abstract：:Rate constant bioaccumulation models are applied to simulate the flow of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in the coastal marine food web of Frierfjorden, a contaminated fjord in southern Norway. We apply two different ways to parameterize the rate constants in the model, global sensitivity...

journal_title：Environmental toxicology and chemistry

authors： Saloranta TM,Andersen T,Naes K

更新日期：2006-01-01 00:00:00

abstract：:Paralytic shellfish toxins are secondary metabolites produced by several species of dinoflagellates and cyanobacteria. Known targets of these toxins, which typically occur at detrimental concentrations during harmful algal blooms, include voltage-gated ion channels in humans and other mammals. However, the effects of ...

journal_title：Environmental toxicology and chemistry

authors： Cusick KD,Wetzel RK,Minkin SC Jr,Dodani SC,Wilhelm SW,Sayler GS

更新日期：2013-06-01 00:00:00

abstract：:Freshwater organisms are increasingly exposed to combinations of stressors. However, because it is time-consuming and costly, research on the interaction of stressors, such as compound toxicity and global warming on vertebrates, is scarce. Studies on multigenerational effects of these combined stressors are almost non...

journal_title：Environmental toxicology and chemistry

authors： Philippe C,Hautekiet P,Grégoir AF,Thoré ESJ,Pinceel T,Stoks R,Brendonck L,Boeck G

更新日期：2018-09-01 00:00:00

abstract：:Spatio-temporal factors strongly influence the population dynamics of animals; thus there have been calls to integrate these factors in environmental impact assessment of toxic compounds. To date, methodological difficulties have probably prevented this union. However, new modeling techniques that could help are avail...

journal_title：Environmental toxicology and chemistry

authors： Topping CJ,Odderskaer P

更新日期：2004-02-01 00:00:00

abstract：:Ionic silver is toxic to aquatic organisms at low concentrations. However, complexation to binding sites on natural organic matter has been shown to reduce silver toxicity. Research indicates that there is a need to develop reliable methods for characterizing silver binding at very low silver ion concentrations where ...

journal_title：Environmental toxicology and chemistry

authors： Rader KJ,Shadi TS,Mahony JD,Di Toro DM

更新日期：2005-11-01 00:00:00

abstract：:Northern bobwhite (quail) (Colinus virginianus) and scaled quail (Callipepla squamata) populations have declined dramatically in the Rolling Plains ecoregion of Texas and Oklahoma (USA). There is rising concern about potential toxicity of neonicotinoids to birds. To investigate this concern, the authors examined crops...

journal_title：Environmental toxicology and chemistry

authors： Turaga U,Peper ST,Dunham NR,Kumar N,Kistler W,Almas S,Presley SM,Kendall RJ

更新日期：2016-06-01 00:00:00

abstract：:Triclosan (TCS; 5-chloro-2-(2,4-dichlorophenoxy)phenol), a common antimicrobial agent, may react with residual chlorine in tap water during transport to wastewater treatment plants or during chlorine disinfection of wastewater, generating chlorinated TCS derivatives (CTDs): 4,5-dichloro-2-(2,4-dichlorophenoxy)phenol (...

journal_title：Environmental toxicology and chemistry

authors： Buth JM,Grandbois M,Vikesland PJ,McNeill K,Arnold WA

更新日期：2009-12-01 00:00:00

abstract：:On release into surface waters, engineered silver nanoparticles (AgNPs) tend to settle to sediments and, consequently, epibenthic fauna will be exposed to them through diet. We established Ag uptake and accumulation profiles over time in the hemolymph of a marine amphipod fed with a formulated feed containing AgNPs or...

journal_title：Environmental toxicology and chemistry

authors： Vannuci-Silva M,Cadore S,Henry TB,Umbuzeiro G

更新日期：2019-04-01 00:00:00

abstract：:Temperature is an important factor affecting toxicity, determining chemical toxicokinetics and toxicodynamics in poikilothermic organisms. Because metabolic rates are also affected by temperature, interactions between the emergence of toxic effects and time are very likely. The aim of the present study was to investig...

journal_title：Environmental toxicology and chemistry

authors： Nørhave NJ,Spurgeon D,Svendsen C,Cedergreen N

更新日期：2014-06-01 00:00:00

abstract：:The influence of dissolved organic carbon (DOC) and water composition on the toxicity of copper to juvenile freshwater mussels (fatmucket, Lampsilis siliquoidea) were evaluated in natural and reconstituted waters. Acute 96-h copper toxicity tests werec onducted at four nominal DOC concentrations (0, 2.5, 5, and 10 mg/...

journal_title：Environmental toxicology and chemistry

authors： Wang N,Mebane CA,Kunz JL,Ingersoll CG,May TW,Arnold WR,Santore RC,Augspurger T,Dwyer J,Barnhart MC

更新日期：2009-11-01 00:00:00

abstract：:Kidney samples of 224 roe deer (113 males, 111 females) aged three months to approximately nine years were collected in eastern Austria. Cadmium contents were examined and histological examinations were performed considering 11 different pathomorphological parameters. Cadmium burden was relatively high (range: 0.010-2...

journal_title：Environmental toxicology and chemistry

authors： Beiglböck C,Steineck T,Tataruch F,Ruf T

更新日期：2002-09-01 00:00:00

abstract：:The degradation of plasticizers by the yeast Rhodotorula rubra J-96-1 (American Type Culture Collection 9449) in the presence of glucose was studied. The plasticizers included the commonly used bis-2-ethylhexyl adipate (B(EH)A), dioctyl phthalate (DOP), and dioctyl terephthalate (DOTP), and the less commonly used dipr...

journal_title：Environmental toxicology and chemistry

authors： Gartshore J,Cooper DG,Nicell JA

更新日期：2003-06-01 00:00:00

abstract：:Nineteen adjuvants, many used as surfactants for aquatic herbicide applications, were applied in static bioassay to bluegill sunfish (Lepomis macrochirus) for 96 h to determine median lethal concentrations (LC50). Surfactants are added to the tank mix as a percentage (v/v) of the total volume, in contrast to herbicide...

journal_title：Environmental toxicology and chemistry

authors： Haller WT,Stocker RK

更新日期：2003-03-01 00:00:00

abstract：:Sulfonamides are a widely used class of antibiotics; however, there are few toxicological data available with which to conduct environmental risk assessments for these compounds. Therefore, the toxicity of four sulfonamides (sulfaguanidine, sulfathiazole, sulfamerazine, and sulfasalazine) to Hyalella azteca was assess...

journal_title：Environmental toxicology and chemistry

authors： Bartlett AJ,Balakrishnan VK,Toito J,Brown LR

更新日期：2013-04-01 00:00:00

abstract：:Monte Carlo simulations were used to evaluate statistical methods for estimating 95% upper confidence limits of mean constituent concentrations for left-censored data with nonuniform detection limits. Two primary scenarios were evaluated: data sets with 15 to 50% nondetected samples and data sets with 51 to 80% nondet...

journal_title：Environmental toxicology and chemistry

authors： Sinha P,Lambert MB,Trumbull VL

更新日期：2006-09-01 00:00:00

abstract：:Field-related influences on polychlorinated biphenyl (PCB) exposure were evaluated by employing caged deposit-feeders, Neanthes arenaceodentata, along with polyoxymethylene (POM) samplers using parallel in situ and ex situ bioassays with homogenized untreated or activated carbon (AC) amended sediment. The AC amendment...

journal_title：Environmental toxicology and chemistry

authors： Janssen EM,Oen AM,Luoma SN,Luthy RG

更新日期：2011-01-01 00:00:00