Abstract:
:Stimulus threshold and response latencies were measured for electrically elicited retinal ganglion cell responses in retina isolated from the eyes of normal and retinal degenerate (rd1) mice. Stimulation of the ganglion cell-side in normal retina yielded a significantly lower mean threshold and shorter latency when compared with stimulation of the photoreceptor side in normal retina. The latency of the ganglion cell-side stimulation in normal retina also proved to be significantly shorter than the latency for stimulation of the ganglion cell side in rd1 retina. Thus both the electrode positioning as well as the health of the retinal tissue play a role in the stimulating current required to elicit a retinal response.
journal_name
Vision Resjournal_title
Vision researchauthors
O'Hearn TM,Sadda SR,Weiland JD,Maia M,Margalit E,Humayun MSdoi
10.1016/j.visres.2006.03.031subject
Has Abstractpub_date
2006-10-01 00:00:00pages
3198-204issue
19eissn
0042-6989issn
1878-5646pii
S0042-6989(06)00190-8journal_volume
46pub_type
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