Abstract:
:The aim of this investigation was to examine the effects of threatening (the sight and barking of the dog) or "Neutral" (flash and tone) stimuli on the emotional-aversive response evoked by direct intracerebral application of carbachol in cats. Unilateral microinjections of carbachol in 10 microgram doses and 2 mu1 volume into anterior hypothalamic/preoptic area caused a full-blown emotional response with marked vocalization. All stimuli which might be threatening for cats caused a significant increase of vocalization. "Neutral" stimuli of comparable intensity were without effect. To investigate the effects of stimulation intensity two clocks: low and loud (difference of 27 dB), were used. The loud click significantly increased vocalization level while the low click of the same intensity as a dog's barking had no significant influence on the carbachol-induced response. Cholinergic stimulation of the anterior hypothalamic/preoptic area seems to be specifically responsible for the obtained change of perception towards increased sensitivity to any potentially threatening alteration of the environment.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Brudzyński SM,Kiełczykowska E,Romaniuk Adoi
10.1016/0166-4328(82)90162-0subject
Has Abstractpub_date
1982-01-01 00:00:00pages
33-43issue
1eissn
0166-4328issn
1872-7549pii
0166-4328(82)90162-0journal_volume
4pub_type
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