Abstract:
:In a study of 80 patients who received 164 treatments with sleep deprivation, the following questions were addressed: Do depressive patients of different subgroups respond differently to sleep deprivation? what complications arise? does the same patient react in the same way to multiple treatments? are there differences between responders and nonresponders? Results indicate that: (1) Endogenous depressions (unipolar, bipolar, and involutional) and psychotic depressions in schizophrenic patients improve significantly the day after sleep deprivation. However, on the second day, after a night's recovery sleep, a significant improvement occurs in neurotic depressives, whereas the endogenous and psychotic depressions worsen again. (2) Schizophrenic patients with a postpsychotic depression respond as well to sleep deprivation as patients with bipolar depression. (3) Complications arise very rarely in sleep deprivation therapy. (4) Patients in all the diagnostic categories studied can respond very differently to multiple treatments with sleep deprivation. (5) Responders and nonresponders do not differ in age, sex, or psychopathological state before sleep deprivation, and psychotropic drugs have no apparent effect on the therapeutic response.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Fähndrich Edoi
10.1016/0165-1781(81)90074-3subject
Has Abstractpub_date
1981-12-01 00:00:00pages
277-85issue
3eissn
0165-1781issn
1872-7123pii
0165-1781(81)90074-3journal_volume
5pub_type
杂志文章abstract::Previous studies suggest that insulin-sensitizing agents could play a significant role in the treatment of major depression, particularly depression in patients with documented insulin resistance or those who are resistant to standard psychopharmacological approaches. This study aimed to assess the effects on depressi...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2015.10.013
更新日期:2015-12-30 00:00:00
abstract::A widespread assumption in research and clinical practice is that cognitive reappraisal is a healthy and successful emotion regulation strategy, while expressive suppression is ineffective and has non-favourable consequences (e.g., decreased positive affect, higher physiological arousal). However, little is known abou...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2012.05.034
更新日期:2012-12-30 00:00:00
abstract::The aim of this study was to assess social- perceptual Theory of Mind in bipolar disorder (BD). 112 euthymic participants with BD I or BD II (65 with BD I and 47 with BD II) were compared to a group of 112 persons with no psychiatric diagnosis and 43 with unipolar depression (UD). They completed the task of the "Readi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.09.039
更新日期:2018-04-01 00:00:00
abstract::Two different initial dosing regimens with clomipramine (CMI) were used to compare early response indicators and dose strategies. Thirty-two inpatients with major depressive disorder were randomized in a double-blind protocol. The pulse-loading group received 150 and 200 mg of CMI on 2 consecutive evenings and then re...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-1781(94)90004-3
更新日期:1994-11-01 00:00:00
abstract::Psychiatric symptoms have been reported for individuals who experience chronic exposure to low levels of organic solvents. However, it is not known what proportion of such individuals experience psychiatric disorder; which specific disorders may be characteristic of this population; or whether bioaccumulation of lead ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(00)00217-1
更新日期:2000-12-27 00:00:00
abstract::Specific patterns of cortical glucose metabolism disturbances and increased CSF phospho-tau (p-tau(181)) concentrations could be demonstrated to predict cognitive decline and shift to dementia in amnestic mild cognitive impairment (MCI). But comparisons of both diagnostic tools have not been undertaken so far. The aim...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2006.12.002
更新日期:2007-07-15 00:00:00
abstract::Reliability and validity of direct visual analogue scale (VAS) ratings of improvement were assessed in 162 patients with Seasonal Affective Disorder, Winter Depression type (W-SAD), after light treatment for 6 consecutive days. The patients were rated with the Montgomery-Asberg Depression Rating Scale (MADRS) and a sc...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(98)00119-x
更新日期:1998-12-14 00:00:00
abstract::The reliability and validity of the Toronto Structured Interview for Alexithymia (TSIA) have been demonstrated in previous studies with English-speaking community and psychiatric samples and a German-speaking psychiatric sample. The aim of this study was to evaluate the psychometric properties of the TSIA in a mixed c...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.02.015
更新日期:2011-05-30 00:00:00
abstract::One inhalation of 35% CO2 in oxygen was administered to 36 patients with anxiety disorders and 14 healthy controls. Eighteen patients had a diagnosis of panic disorder (PD) and 18 of obsessive-compulsive disorder (OCD). As a placebo control for CO2, compressed air was administered in a double-blind design. Immediately...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(90)90121-k
更新日期:1990-02-01 00:00:00
abstract::In the current cross-sectional study, we aimed to investigate the presence and severity of "male" depressive symptoms and suicidal behaviors in psychiatric patients with and without a history of child abuse and neglect, as measured by the Childhood Trauma Questionnaire (CTQ), as well as to explore the associations amo...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.07.056
更新日期:2014-12-15 00:00:00
abstract::An epidemiological survey on anorexia nervosa was performed in Japanese hospitals in 1985 and 1992 using a questionnaire. The reported number of patients with anorexia nervosa was 2391 from 732 institutions. From these data, the total number of anorexia nervosa patients treated in 1985 in Japanese hospitals was estima...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/0165-1781(96)02988-5
更新日期:1996-04-16 00:00:00
abstract::Pediatric Bipolar Disorder (PBD) is a highly heritable condition responsible for 18% of all pediatric mental health hospitalizations. Despite the heritability of this disorder, few studies have assessed potential differences in the clinical manifestation of PBD among patients with a clear parental history of BD. Addit...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.112501
更新日期:2019-10-01 00:00:00
abstract::Falls are common in older adults with psychiatric disorders, but the epidemiological findings have been inconsistent. This meta-analysis examined the prevalence of falls in older psychiatric patients and its moderating factors. PubMed, EMBASE, Web of Science and PsycINFO databases were independently searched by three ...
journal_title:Psychiatry research
pub_type: 杂志文章,meta分析
doi:10.1016/j.psychres.2018.12.165
更新日期:2019-03-01 00:00:00
abstract::Mental disorders and sleep dysfunction are common among Chinese university students. This study aimed to evaluate a low cost scalable mindfulness intervention program to improve psychological health and sleep quality among Chinese university students. A randomized controlled trial with 101 university students (mean ag...
journal_title:Psychiatry research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psychres.2018.09.060
更新日期:2018-12-01 00:00:00
abstract::The neurocircuitries subserving affective and olfactory processes overlap, are sexually dimorphic, and show disruptions in schizophrenia, suggesting their intersection may be a window on the core process producing psychosis. This study investigated diagnostic and sex differences in hedonic judgments of odors and smell...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.058
更新日期:2018-11-01 00:00:00
abstract::Posttraumatic stress disorder (PTSD) is an anxiety- and memory-based disorder. The hippocampus and amygdala are key areas in mood regulation. Fluoxetine was found to improve the anxiety-related symptoms of PTSD patients. However, little work has directly examined the effects of fluoxetine on the hippocampus and the am...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.02.011
更新日期:2015-05-30 00:00:00
abstract::The utility of non-invasive brain stimulation techniques to alleviate resistant delusions in schizophrenia is an under-researched area. In this study, we report the effectiveness of alpha transcranial alternating current stimulation (tACS) targeting the medial prefrontal cortex in ameliorating persistent delusions. Tw...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113106
更新日期:2020-08-01 00:00:00
abstract::The tryptophan catabolite (TRYCAT) pathway is induced by indoleamine 2,3-dioxygenase (IDO), which upon activation depletes plasma tryptophan (TRP) and increases the synthesis of TRYCATs. Both phenomena are associated with somatization and depression. The aims of this study are to examine whether disorders in the TRYCA...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.09.029
更新日期:2012-04-30 00:00:00
abstract::High rates of psychiatric impairment in adults with 22q11 deletion syndrome (22q11DS, also referred to as DiGeorge or velocardiofacial syndrome) suggest that behavioral trajectories of children with 22q11DS may provide critical etiologic insights. Past findings that report Diagnostic and Statistical Manual (DSM) diagn...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.03.023
更新日期:2009-03-31 00:00:00
abstract::To date, there are no data on quality of life (QOL) and its correlates in homeless Chinese patients with psychiatric disorders. This study aimed to compare QOL between homeless and non-homeless patients with psychiatric disorders in China. A total of 278 homeless and 222 non-homeless patients matched in age and gender...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.016
更新日期:2017-03-01 00:00:00
abstract::Wells's (2009) metacognitive theory suggests that inflexible and recurrent styles of thinking in response to negative thoughts, feelings, and beliefs underlie mood and anxiety symptoms. Wells termed such styles of thinking as the cognitive attentional syndrome (CAS). Using a clinical sample (N=132) of patients with ei...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.04.020
更新日期:2013-11-30 00:00:00
abstract::To test the clinical efficacy of low dose fluphenazine decanoate (1.25 mg to 5.0 mg biweekly), we carried out two separate experiments: (1) an open trial in 57 schizophrenic outpatients, lasting 6 months; (2) a double-blind, placebo-controlled discontinuation study in a subgroup of patients who maintained good remissi...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/0165-1781(79)90016-7
更新日期:1979-12-01 00:00:00
abstract::The back-to-back (BTB) acquisition of MP-RAGE MRI scans of the Alzheimer׳s Disease Neuroimaging Initiative (ADNI1) provides an excellent data set with which to check the reproducibility of brain atrophy measures. As part of ADNI1, 131 subjects received BTB MP-RAGEs at multiple time points and two field strengths of 3T...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2014.07.002
更新日期:2014-10-30 00:00:00
abstract::Alcohol misuse is associated with negative mental and physical health outcomes, which presents a public health concern in veterans. However, less is known regarding outcomes among veterans with low to moderate alcohol consumption. This study included veterans with military service in Iraq and/or Afghanistan (N = 1083)...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.09.067
更新日期:2018-01-01 00:00:00
abstract::Previous studies that operationalized reactive aggression using behavioral observations in general populations have not taken into account the type of stimulus that elicits reactive aggression. In the present study we define a specific form of reactive aggression, i.e., reactive aggression in response to neutral behav...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.08.006
更新日期:2010-04-30 00:00:00
abstract::Kynurenine pathway (KP) activation is associated with many neuropsychiatric diseases, such as major depressive disorder (MDD) and Alzheimer's disease (AD). Investigations conducted on MDD seldom shed light on KP changes in late-life depression (LLD), though memory deficit (MD) in patients with LLD is a predictable sig...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.08.041
更新日期:2018-11-01 00:00:00
abstract::Over the years, schizophrenia is speculated to be associated with immune or inflammatory reactions mediated by cytokines. It is proposed that chronic inflammation might damage the micro-vascular system of brain and hamper cerebral blood flow. Scientific evidence suggests that an increase of stress hormone like norepin...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2014.02.004
更新日期:2014-05-15 00:00:00
abstract::Comorbid depression is frequent in obsessive-compulsive disorder (OCD) and is acknowledged as a major confound in biological and neurocognitive investigations in OCD. The aim of the present study was to assess the distribution of depressive symptoms in a large OCD sample (n=162) and to analyze the dimensional structur...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2003.11.003
更新日期:2004-02-15 00:00:00
abstract::Posttraumatic stress disorder (PTSD) research has focused largely on fear processing. However, interpersonal trauma exposure can also impact interpersonal functioning and the perception of the trustworthiness of others. The present study examined facial perceptions of fearfulness and trustworthiness in individuals wit...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2016.01.056
更新日期:2016-03-30 00:00:00
abstract::As the serotonin transporter gene (SLC6A4 or 5-HTT) is a key regulator of central serotonergic activity, several association studies between Antisocial Personality Disorder (APD) and the SLC6A4 polymorphisms have been conducted in the last decade. In the present study, the role of both 5-HTTLPR and 5-HTTVNTR polymorph...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2008.12.018
更新日期:2010-05-15 00:00:00