Elastin fibers in the sputum of patients with necrotizing pneumonia.

Abstract:

:We have observed five patients for whom the presence of fibers of elastin in potassium hydroxide (KOH) preparations of sputum represented the first evidence of necrotizing pulmonary disease. In four cases, the discovery of elastin fibers in sputum provided additional evidence supporting initiation or modification of antibiotic therapy. Necrotizing disease was confirmed in all cases by autopsy or by the development of cavitation on chest x-ray film. Cytochemical staining, electron microscopy, and elastase digestion all suggest that the refractile fibers seen on KOH wet mount of sputum are elastin. The test, first described in 1846, is simple to perform, requires little experience to read, and may be a valuable adjunct to the chest roentgenogram in the diagnosis of pulmonary parenchymal destruction.

journal_name

Chest

journal_title

Chest

authors

Shlaes DM,Lederman M,Chmielewski R,Tweardy D,Wolinsky E

doi

10.1378/chest.83.6.885

subject

Has Abstract

pub_date

1983-06-01 00:00:00

pages

885-9

issue

6

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)33929-5

journal_volume

83

pub_type

杂志文章

相关文献

CHEST文献大全
  • Retrieval of embolized central venous catheters by a Dormia ureteral stone dislodger with straight filiform tip.

    abstract::Two cases are presented in which a Dormia ureteral stone dislodger with straight filiform tip was used to retrieve broken central venous pressure catheters from the right side of the heart and vena cavae. It should be emphasized that this particular model is more easily passed into the vascular system and more easily ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.69.3.435

    authors: Drabinsky M

    更新日期:1976-03-01 00:00:00

  • Comparing cost of indwelling pleural catheter vs talc pleurodesis for malignant pleural effusion.

    abstract:BACKGROUND:Malignant pleural effusion is associated with short life expectancy and significant morbidity. A randomized controlled trial comparing indwelling pleural catheters (IPCs) with talc pleurodesis found that IPCs reduced in-hospital time and the need for additional procedures but were associated with excess adve...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.13-2481

    authors: Penz ED,Mishra EK,Davies HE,Manns BJ,Miller RF,Rahman NM

    更新日期:2014-10-01 00:00:00

  • Exercise outcomes after pulmonary rehabilitation depend on the initial mechanism of exercise limitation among non-oxygen-dependent COPD patients.

    abstract:STUDY OBJECTIVES:Pulmonary rehabilitation (PR) that includes exercise training can improve exercise tolerance and quality of life for patients with COPD. However, the degree of benefit from PR is variable. We hypothesized that the exercise response to PR varies depending on the initial factors that limit exercise. DES...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.127.1.110

    authors: Plankeel JF,McMullen B,MacIntyre NR

    更新日期:2005-01-01 00:00:00

  • Residual volume in a general population. Effects of body size, age, cigarette smoking, and respiratory symptoms.

    abstract::Residual volume (RV) was obtained by subtracting vital capacity from total lung capacity determined by the single breath helium dilution (TLCsb) to measure CO diffusing capacity in 2,680 subjects (8 to 64 years old) of a general population sample. There were 712 normal subjects (243 male and 469 female subjects) selec...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.4.1209

    authors: Paoletti P,Viegi G,Carrozzi L,Di Pede F,Modena P,Ballerin L,Baldacci S,Pedreschi M,Pistelli G,Giuntini C

    更新日期:1992-10-01 00:00:00

  • Cost analyses of community-acquired pneumonia from the hospital perspective.

    abstract:STUDY OBJECTIVES:Community-acquired pneumonia (CAP) is a widespread disease with important implications for health-care systems worldwide. This study investigated direct costs, treatment patterns, and outcomes associated with two patient cohorts hospitalized with CAP. DESIGN:The study design was naturalistic, prospect...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.128.4.2238

    authors: Bauer TT,Welte T,Ernen C,Schlosser BM,Thate-Waschke I,de Zeeuw J,Schultze-Werninghaus G

    更新日期:2005-10-01 00:00:00

  • Sleep medicine training across the spectrum.

    abstract::There is now a new pathway and examination for sleep medicine, sponsored by the American Board of Internal Medicine, and a number of accredited sleep medicine fellowship programs through the Accreditation Council for Graduate Medical Education. This review takes an historical approach to discuss the process of educati...

    journal_title:Chest

    pub_type: 历史文章,杂志文章,评审

    doi:10.1378/chest.10-0783

    authors: Strohl KP

    更新日期:2011-05-01 00:00:00

  • Transesophageal echocardiographic diagnosis of anomalous left coronary artery from the right aortic sinus.

    abstract::Patients with anomalous left main coronary artery arising from the right sinus of Valsalva and coursing posteriorly between the aorta and the pulmonary artery are prone to sudden death. We present a patient with this entity in whom the diagnosis was made by transesophageal two-dimensional echocardiography and coronary...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.5.1617

    authors: Alam M,Brymer J,Smith S

    更新日期:1993-05-01 00:00:00

  • The physiologic evaluation of patients with lung cancer being considered for resectional surgery.

    abstract::The preoperative physiologic assessment of a patient being considered for surgical resection of lung cancer must consider the immediate perioperative risks from comorbid cardiopulmonary disease, the long-term risks of pulmonary disability, and the threat to survival due to inadequately treated lung cancer. As with any...

    journal_title:Chest

    pub_type: 指南,杂志文章,实务指引

    doi:10.1378/chest.123.1_suppl.105s

    authors: Beckles MA,Spiro SG,Colice GL,Rudd RM,American College of Chest Physicians.

    更新日期:2003-01-01 00:00:00

  • The clinician's perspective on parapneumonic effusions and empyema.

    abstract::Respondents at an interactive symposium on pleural space infections (n = 339) at the 1991 American College of Chest Physicians Annual Scientific Assembly recorded their personal management preferences for hypothetical patients with empyema. The group's preference was to treat pleural sepsis from an anaerobic multilocu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.1.259

    authors: Strange C,Sahn SA

    更新日期:1993-01-01 00:00:00

  • The impact of associated diabetic retinopathy on stroke and severe bleeding risk in diabetic patients with atrial fibrillation: the loire valley atrial fibrillation project.

    abstract:BACKGROUND:Diabetes mellitus is recognized as a stroke risk factor in atrial fibrillation (AF). Patients with diabetes with retinopathy have an increased risk for systemic cardiovascular complications, and severe diabetic retinopathy predisposes to ocular bleeding. We hypothesized that patients with diabetes, retinopat...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.14-2096

    authors: Lip GYH,Clementy N,Pierre B,Boyer M,Fauchier L

    更新日期:2015-04-01 00:00:00

  • Left subclavian steal, interrupted aortic arch, complete transposition of the great vessels and single left ventricle.

    abstract::Congenital subclavian steal consists of atresia of the proximal end of the subclavian artery, while the blood supply to the distal portion of the subclavian artery originates from the circle of Willis. It should be suspected in complicated malformations of the heart associated with marked hypoplasia or interruption of...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.67.3.352

    authors: Garcia O,Wilkins R,Cunha D,Jesse MJ

    更新日期:1975-03-01 00:00:00

  • Expression of the atypical chemokine receptor D6 in human alveolar macrophages in COPD.

    abstract:BACKGROUND:D6 is an atypical chemokine receptor involved in chemokine degradation and resolution of acute inflammatory responses in mice. Emerging evidence suggests that D6 might behave differently in human chronic inflammatory conditions. We, therefore, investigated the involvement of D6 in the immune responses in COP...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-3220

    authors: Bazzan E,Saetta M,Turato G,Borroni EM,Cancellieri C,Baraldo S,Savino B,Calabrese F,Ballarin A,Balestro E,Mantovani A,Cosio MG,Bonecchi R,Locati M

    更新日期:2013-01-01 00:00:00

  • Management of primary mediastinal seminoma.

    abstract::Radiation therapy has been the usual initial treatment for mediastinal seminoma in the past. However, 25 to 40 percent of patients are not cured by this therapy, and other therapy is needed. Review of case reports show that vinblastine, bleomycin, and cis-platinum are effective therapy for metastatic disease, advanced...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.83.2.263

    authors: Clamon GH

    更新日期:1983-02-01 00:00:00

  • Usefulness of fine-needle aspiration biopsy of spleen in diagnosis of sarcoidosis.

    abstract::Fine-needle aspiration biopsy of the spleen was carried out in 557 patients. In 381 cases, the aspiration was performed because of suspected sarcoidosis. The sensitivity of the technique was 59 percent and the specificity 97 percent. The cytologic picture of the spleen was abnormal in 184 patients with sarcoidosis and...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.83.2.193

    authors: Selroos O,Koivunen E

    更新日期:1983-02-01 00:00:00

  • Pulmonary emboli in patients receiving chemotherapy for non-Hodgkin's lymphoma.

    abstract::Combination chemotherapy has dramatically improved the prognosis of patients with intermediate and high grade histologic subtypes of non-Hodgkin's lymphomas. Treatment-related complications, however, are considerable, and a common problem encountered is respiratory distress or respiratory insufficiency. Usually these ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.94.3.589

    authors: Glenn LD,Armitage JO,Goldsmith JC,Sorensen S,Howe D,Weisenberger DD

    更新日期:1988-09-01 00:00:00

  • Transition from epoprostenol and treprostinil to the oral endothelin receptor antagonist bosentan in patients with pulmonary hypertension.

    abstract:STUDY OBJECTIVES:Prior to the availability of the oral endothelin antagonist bosentan, most patients with pulmonary arterial hypertension (PAH) were treated with continuously infused prostacyclins. Many patients receiving prostacyclins would have received bosentan if it had been available at the time of their diagnosis...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.126.3.808

    authors: Suleman N,Frost AE

    更新日期:2004-09-01 00:00:00

  • Disseminated histoplasmosis followed by disseminated coccidioidomycosis.

    abstract::A case of disseminated histoplasmosis followed later by disseminated coccidioidomycosis is described. The clinical illness and immunologic studies suggest subtle defects that may have existed antecedent to infection and, thus, provided an opportunity for widespread dissemination by these normally nonopportunistic orga...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.72.2.238

    authors: Kaplan P,Graybill JR,Thor D

    更新日期:1977-08-01 00:00:00

  • Tetralogy of Fallot with discrete fibrous subaortic stenosis.

    abstract::This is the first reported case of discrete fibrous subaortic stenosis in tetralogy of Fallot. Transaortic excision of the subaortic membrane was readily accomplished. To detect this and other forms of left ventricular outflow-tract obstruction in tetralogy of Fallot before surgery, routine selective left ventriculogr...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.69.4.543

    authors: Sanders JH,Van Praagh R,Sade RM

    更新日期:1976-04-01 00:00:00

  • Factors related to diagnostic sensitivity using an ultrathin bronchoscope under CT guidance.

    abstract:BACKGROUND:We investigated factors related to the diagnostic sensitivity of CT-guided transbronchial biopsy (TBB) using an ultrathin bronchoscope and virtual bronchoscopy (VB) navigation for small peripheral pulmonary lesions. METHOD:We have performed this procedure on 83 patients with 85 small peripheral pulmonary le...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.06-0786

    authors: Shinagawa N,Yamazaki K,Onodera Y,Asahina H,Kikuchi E,Asano F,Miyasaka K,Nishimura M

    更新日期:2007-02-01 00:00:00

  • Serial exercise testing in pulmonary embolism.

    abstract::A patient underwent exercise testing during evaluation for unexplained dyspnea. Evidence of ventilation-perfusion mismatch was noted and subsequent testing revealed multiple pulmonary emboli. Ventilation perfusion parameters by serial exercise testing progressively improved during the course of the patient's illness b...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.94.3.517

    authors: Helmers RA,Zavala DC

    更新日期:1988-09-01 00:00:00

  • Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders.

    abstract::Transforming growth factor (TGF)-beta is a multifunctional protein that initiates its diverse cellular responses by binding to and activating specific type I and type II serine/threonine kinase receptors. TGF-beta can act as a regulator of proliferation, migration, survival, differentiation, and extracellular matrix s...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.128.6_suppl.585S

    authors: Bertolino P,Deckers M,Lebrin F,ten Dijke P

    更新日期:2005-12-01 00:00:00

  • Cross-sectional echocardiographic observations on the mechanism of preservation of the opening snap in calcific mitral stenosis.

    abstract::Cross-sectional echocardiography (CSE) was performed on 19 patients with mitral stenosis (MS). Nine patients (group 1) had little or no mitral valve (MV) calcification; ten patients (group 2) had heavy MV calcification. An opening snap was present in each of the patients in group 1. Of the group 2 patients, five (grou...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.78.6.822

    authors: Chandraratna PA,Aronow WS,Lurie M

    更新日期:1980-12-01 00:00:00

  • Pharmacodynamics of levofloxacin in patients with acute exacerbation of chronic bronchitis.

    abstract:STUDY OBJECTIVES:Levofloxacin is a fluoroquinolone antimicrobial agent for which pharmacodynamic relationships between the maximum serum antibiotic concentration (Cmax)/minimum inhibitory concentration (MIC) ratio and/or the area under the serum concentration-time curve during a 24-h dosing period (AUC(0-24))/MIC ratio...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.128.4.2093

    authors: Cazzola M,Matera MG,Donnarumma G,Tufano MA,Sanduzzi A,Marchetti F,Blasi F

    更新日期:2005-10-01 00:00:00

  • Hydrofluoroalkane-134a beclomethasone dipropionate, 400 microg, is as effective as chlorofluorocarbon beclomethasone dipropionate, 800 microg, for the treatment of moderate asthma.

    abstract:OBJECTIVE:The improved lung deposition of hydrofluoroalkane-134a beclomethasone dipropionate (HFA-BDP) extrafine aerosol compared with chlorofluorocarbon beclomethasone dipropionate (CFC-BDP) suggests that lower doses of HFA-BDP may be required to provide equivalent asthma control. The present study was undertaken to t...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.115.2.343

    authors: Gross G,Thompson PJ,Chervinsky P,Vanden Burgt J

    更新日期:1999-02-01 00:00:00

  • Validation of the Exhaled Breath Temperature Measure: Reference Values in Healthy Subjects.

    abstract:BACKGROUND:Exhaled breath temperature (EBT) is a new noninvasive method for the study of inflammatory respiratory diseases with a potential to reach clinical practice. However, few studies are available regarding the validation of this method, and they were mainly derived from small, pediatric populations; thus, the ra...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2016.11.013

    authors: Carpagnano GE,Foschino-Barbaro MP,Crocetta C,Lacedonia D,Saliani V,Zoppo LD,Barnes PJ

    更新日期:2017-04-01 00:00:00

  • Usual interstitial pneumonia associated with primary Sjögren's syndrome.

    abstract::We describe the first case, to our knowledge, of usual interstitial pneumonia (UIP) as the pulmonary manifestation in primary Sjögren's syndrome (SjS). A 45-year-old woman was admitted to our hospital because of a dry cough and an interstitial shadow on a chest roentgenogram. Labial biopsy and sialogram confirmed a di...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.6.1756

    authors: Kadota J,Kusano S,Kawakami K,Morikawa T,Kohno S

    更新日期:1995-12-01 00:00:00

  • Catamenial hemoptysis. New methods of diagnosis and therapy.

    abstract::Bronchopulmonary endometriosis is a rare cause of hemoptysis. We describe a woman with catamenial hemoptysis which was localized with chest CAT scanning and treated successfully with danazol. The proposed pathogenesis and manifestations of thoracic endometriosis are reviewed, and the use of new diagnostic and therapeu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.87.5.687

    authors: Elliot DL,Barker AF,Dixon LM

    更新日期:1985-05-01 00:00:00

  • Legionnaires' disease. Association with severe bronchospasm and hypoventilation.

    abstract::A 31-year-old man with legionnaires' disease, who presented with severe pneumonia and hypoxemia, later developed severe bronchospasm and marked hypercapnia, a complication not previously reported in Legionella infection. He responded to therapy with erythromycin and a bronchodilator. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.82.3.382

    authors: Rosenberg DM,Martin L,Lerner P,Parker DM

    更新日期:1982-09-01 00:00:00

  • Patterns of Use of Adjunctive Therapies in Patients With Early Moderate to Severe ARDS: Insights From the LUNG SAFE Study.

    abstract:BACKGROUND:Adjunctive strategies are an important part of the management of ARDS. However, their application in clinical practice remains inconsistent. RESEARCH QUESTION:We wished to determine the frequency and patterns of use of adjunctive strategies in patients with moderate to severe ARDS (Pao2/Fio2 [P/F ratio] < 1...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.01.041

    authors: Duggal A,Rezoagli E,Pham T,McNicholas BA,Fan E,Bellani G,Rubenfeld G,Pesenti AM,Laffey JG,LUNG SAFE Investigators and the ESICM Trials Group.

    更新日期:2020-06-01 00:00:00

  • International trends in asthma mortality rates in the 5- to 34-year age group: a call for closer surveillance.

    abstract:BACKGROUND:International time trends in asthma mortality have played an important sentinel role in the identification of two epidemics of asthma mortality in some countries in the 1960s and the 1970s and 1980s. Since then, little attention has been paid to the ongoing international time trends. METHODS:Country-specifi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-2082

    authors: Wijesinghe M,Weatherall M,Perrin K,Crane J,Beasley R

    更新日期:2009-04-01 00:00:00