Abstract：
:Activation and inhibition of the calcium release channel of rabbit skeletal muscle heavy sarcoplasmic reticulum (HSR) was investigated by various methods. The calcium release channel is activated by binding of calcium in the micromolar range and by binding of adenine nucleotides in the millimolar range. Ruthenium red and neomycin are potent inhibitors of the channel at nanomolar to micromolar concentrations. Dantrolene inhibits the rate of caffeine-induced calcium release. Several models of the calcium release channel were considered to explain the three-phasic calcium release from HSR vesicles. Simulation of calcium efflux data according to various models suggest that the calcium release channel has at least three states. The experimental results can be explained by assuming one open and two closed states of the calcium release channel, but not by assuming one open and one closed state.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Suko J,Wyskovsky W,Hohenegger M,Plank B,Bertel O,Klein S,Hellmann Gsubject
Has Abstractpub_date
1990-10-26 00:00:00pages
616-21issue
20eissn
0043-5325issn
1613-7671journal_volume
102pub_type
杂志文章abstract：:Idiopathic bronchiolitis obliterans organizing pneumonia (idiopathic BOOP) and idiopathic CD4+ T lymphocytopenia are syndromes of unknown origins which have been characterized in recent years. An important feature of both syndromes is the good prognosis. The clinical and histological features of idiopathic BOOP are un...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:The psychometric properties of an instrument, the Activity Scale for Kids-performance (ASKp), were assessed which was proposed to capture physical functioning after allogeneic hematopoietic stem cell transplantation (HSCT). Additionally, this multicenter observational prospective study investigated the influ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,多中心研究
doi：10.1007/s00508-020-01641-w
更新日期：2021-01-01 00:00:00
abstract：:On the occasion of the centenary of Prof. Dr. W. Denk's birth, a short survey is given of the advances in the surgical management of fractures in the region of the hip joint in the post-Denk era. It was Denk who encouraged his colleagues to undertake the first nailing of a collum femoris fracture according to Smith-Pe...
journal_title：Wiener klinische Wochenschrift
pub_type： 历史文章,杂志文章
doi：
更新日期：1982-04-02 00:00:00
abstract：:Chronic recurrent pulmonary embolism can lead to extensive pulmonary hypertension by obstruction of the pulmonary vessels. Pulmonary thrombendarteriectomy is a new approach to normalizing the elevated pulmonary vascular resistance by removal of the adsorbed thrombi. Between 1992 and 1994 we have operated on 8 patients...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:Down syndrome is the most commonly occurring chromosomal condition with a prevalence of 11.2-10000 life-births in Europe. The most important concern consists of various degrees of intellectual disability and sensory deficits. The overall prevalence of ophthalmologic abnormalities has been reported to be as h...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-015-0750-6
更新日期：2015-08-01 00:00:00
abstract：:The following parameters have been examined in twenty-one patients suffering from chronic renal failure (creatinine level between 4.5 and 18.8 mg/100 ml serum): maximum motor nerve conduction of the peroneal nerve, amplitude of the compound muscle action potential of the extensor digitorum brevis muscle, serum creatii...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1976-12-10 00:00:00
abstract：:From 1977 to 1982 a prospective randomized double-blind study comparing transfer-factor (TF) versus placebo was conducted in invasive cervical cancer patients after radical surgery and irradiation. The husbands of the cancer patients were selected as leukocyte donors for TF preparations. 60 patients entered the study;...
journal_title：Wiener klinische Wochenschrift
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1983-10-28 00:00:00
abstract：:The plasma levels of hydrocortisone, prednisolone and fluocortolone were studied in healthy males by a competitive protein-binding technique after separation by thin-layer chromatography. Cortisone showed a mean morning level of 440 nmol/l +/- 165 nmol/l and a half life of 4.8 hours. The half life of prednisolone was ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1981-11-13 00:00:00
abstract：:In the small and large intestine Na and Cl are absorbed via active transport systems, whereas K appears to distribute passively between the lumen and the blood side of the epithelium. Three types of Na influx mechanisms across the luminal cell membrane of the epithelium may be distinguished: 1. In the gall bladder and...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1980-10-10 00:00:00
abstract：:Within the framework of an experimentally introduced curriculum in Medical Physiology during the past three years, voluntary tests of the multiple-choice type were offered at the end of each term in order to provide students with feedback on their achievements. Positive results contribute to the final grade. Analysis ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1979-07-13 00:00:00
abstract：:Lymphangiomas are uncommon lesions of lymphatic channels that are often present at birth and diagnosed mostly (90%) before the age of two years. Lymphangiomas occur exceedingly rarely in adults and few cases are described in the literature. The treatment of choice is complete surgical removal; however, the tumor tends...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-008-0950-4
更新日期：2008-01-01 00:00:00
abstract：:Clear cell carcinoma arising in a cesarean section scar is extremely rare. Due to the rarity of the tumor, treatment strategies still need to be further elucidated. We report a case of a woman with a clear cell carcinoma of 10 cm outside the abdominal cavity in her cesarean section scar. Staging surgery revealed two l...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-014-0619-0
更新日期：2015-01-01 00:00:00
abstract：:A new fixed-dose combination drug, Minotensin (1 film-coated tablet contains 120 mg bupranolol, 2.5 mg bendroflumethiazide and 25 mg triamterene) was tested in a long-term study. 20 patients with mild to moderate primary hypertension were treated for 6 months. Items of investigation were: influence on low range serum ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1986-01-24 00:00:00
abstract：:Pompe disease is a storage disorder characterized by deficient or absent activity of the enzyme acid alpha-glucosidase. As a result of ineffective metabolism, glycogen accumulates in muscle tissues. Patients with a classic infantile-onset form present by the first few months of life with hypertrophic cardiomyopathy an...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-013-0475-3
更新日期：2014-02-01 00:00:00
abstract：:The National Lung Screening Trial (NLST) could demonstrate, for the first time, in a prospective randomized trial, that low-dose CT screening (LD-CT) may decrease lung cancer mortality. At the moment, it is unclear how these results will be applicable to Austria. Specifically, the definition of the population at an in...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-013-0356-9
更新日期：2013-06-01 00:00:00
abstract：:Feinstein's opinion that diseases overlap does not stand up to professional criticism. Different diseases can certainly present very similarly, but they cannot overlap, in the same way as specialties cannot overlap. The specialties are separated from each other according to their different connections with the disease...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1989-03-17 00:00:00
abstract：:Because pulmonary embolism (PE) and its treatment carry substantial risk of morbidity and mortality, accurate diagnosis is essential. We report two cases with allergic reactions, in which PE was suggested by routine ECG and D-dimer elevation and strengthened by spiral CT. Therapy with low-molecular-weight heparin was ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/BF03040891
更新日期：2003-10-31 00:00:00
abstract：:This article undertakes a critical evaluation of Adlerian dream theory. The main weakness of the theory is found to be its lack of an inherent instance of truth that shows the dreamer the way to a better and more feasible life style. Contemporary Adlerians' treatment of the master's dream dogmas and their practical us...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：
更新日期：1988-05-13 00:00:00
abstract：:48 patients with nonseminomatous testicular tumours were treated between 1980 and 1984. 19 patients had bulky stage II c or disseminated disease; according the Royal Marsden staging classification 5 patients had stage II c, 2 patients III and 12 patients stage IV. The pT stage of the primary tumour showed no correlati...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1986-08-08 00:00:00
abstract：BACKGROUND:Oxidative stress is well believed to play a role in the pathogenesis of acute ischemic stroke. Reports on antioxidant enzyme activities in patients with stroke are conflicting. Therefore, the aim of this study was to investigate serum antioxidant enzyme activities and oxidative stress levels in patients with...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-015-0742-6
更新日期：2016-03-01 00:00:00
abstract：:We report on a 64-year-old patient with a recurrent endometrial carcinoma which was associated with disseminated intravascular coagulation (DIC) and excessive hyperfibrinolysis. The patient presented with severe bleeding due to hypofibrinogenemia. Fibrin degradation products were excessively elevated and there were al...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1998-01-30 00:00:00
abstract：:Despite the administration of antimalarial treatment, severe malaria still has a high mortality rate. Since overall survival is associated with total parasite biomass, whole blood exchange (e.g. blood exchange transfusions) has been proposed as a potential method to rapidly reduce peripheral parasitaemia. Automated re...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章,评审
doi：10.1007/s00508-012-0238-6
更新日期：2012-11-01 00:00:00
abstract：:Mucopolysaccharidosis V (Scheie's syndrome, MPS-IS) is a very rare, autosomal recessively inherited metabolic disease. The degradation of dermatan sulphate and heparan sulphate is disturbed due to alpha-L-iduronidase deficiency, leading to intracellular storage and excessive urinary secretion of these substances. The ...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1978-12-08 00:00:00
abstract：BACKGROUND:The 6 min pegboard and ring test (6PBRT) is a valid and reproducible test of unsupported arm exercise endurance. The aim of this study was to determine the associations between the 6PBRT, activities of daily living (ADL) and hemoglobin levels in chronic obstructive pulmonary disease (COPD). METHODS:This stu...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-020-01635-8
更新日期：2020-03-25 00:00:00
abstract：:Antibodies to HHV-6 were detected by immunofluorescence in 8.04% of 460 healthy blood donors in West Austria. Testing sera from patients with acute or reactivated infections with other herpesviruses, such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus (HSV) and varicella zoster virus (VZV) we...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1989-06-23 00:00:00
abstract：:97 chronic alcoholic patients were investigated with regard to exocrine pancreatic function. Chronic calcifying pancreatitis was radiologically established in 7.2% of the cases. Secretin-pancreozymin tests were performed in 30 patients. Pancreatic insufficiency was found in 8 patients, while 8 patients showed marked h...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1977-06-24 00:00:00
abstract：:The serum HPL level was studied in normal and high-risk pregnancies. 30 patients with premature labour showed significantly decreased levels. In 24 patients with monosymptomatic toxaemia, HPL patterns showed a statistically significant deviation from the normal standard curve; a highly significant decrease was observe...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1975-09-05 00:00:00
abstract：:Heparin-induced thrombocytopenia is an immuno-mediated life-threatening side effect of heparin therapy which poses difficulties in diagnosis and major therapeutic problems. Heparin must be instantly discontinued. We describe the case of a 60-year-old male patient with type II heparin-induced thrombocytopenia, complica...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：
更新日期：1997-02-28 00:00:00
abstract：AIM:Sleep disordered breathing (SDB) is an inevitable complication of progressive neuromuscular disorders (NMD). Aim of the study was to prospectively investigate the impact of three months of non-invasive ventilation (NIV) on sleep and SDB-associated symptoms in children and adolescents with advanced NMD. METHODS:Twe...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/BF03040405
更新日期：2003-12-30 00:00:00
abstract：PURPOSE:The aim of this systematic review is to provide an update on the effects of resistance exercise (RE) in patients with prostate cancer (PCa), with special attention to the effects on sexual health. METHODS:A systematic search of the literature was conducted in March 2020 using the databases PubMed, MEDLINE, EMB...
journal_title：Wiener klinische Wochenschrift
pub_type： 杂志文章
doi：10.1007/s00508-020-01713-x
更新日期：2020-08-01 00:00:00
